Syncope

Also known as: Fainting / [D]Syncope and collapse NOS / Swooning / Syncopal attack / Syncope and collapse / Faintness / Faint / Passed out / Falling out / Collapse transient / Collapse fleeting / Blackout

DrugDrug NameDrug Description
DB00668EpinephrineEpinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new products/biosimilars and dosage routes have been approved under various names over the last several decades [L4355], [L4356], [L4358]. On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. Dosage delivery routes for epinephrine include intravenous, inhalation, nebulization, intramuscular injection, and subcutaneous injection. In general, the most common uses of parenteral epinephrine are to relieve respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity (anaphylactic or anaphylactoid) reactions to drugs, animal serums and other allergens, and to prolong the action of infiltration anesthetics [F2136]. In addition to the above functions, epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest [A37697], [A37699]. It can be used in severe cases of croup [L4824].
DrugDrug NamePhaseStatusCount
DB00284Acarbose2Recruiting1
DB06262Droxidopa2Recruiting1
DB00571Propranolol2Completed1
DB00626Bacitracin3Recruiting1
DB01190Clindamycin3Recruiting1
DB01137Levofloxacin3Recruiting1
DB09153Sodium chloride3Recruiting1
DB00211MidodrineNot AvailableCompleted1
DB04899NesiritideNot AvailableCompleted1
DB00277TheophyllineNot AvailableRecruiting1