Invasive Fungal Infections

Also known as: Invasive Mycosis / Infection, Invasive Fungal / Invasive Fungal Infection / Invasive Infection, Fungal / Systemic fungal infection NOS / Disseminated mycosis / Systemic mycosis

DrugDrug NameDrug Description
DB00681Amphotericin BAmphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. The antibiotic is without effect on bacteria, rickettsiae, and viruses.
DrugDrug NamePhaseStatusCount
DB00362Anidulafungin1Completed1
DB01141Micafungin2Completed1
DB15245Olorofim2Recruiting1
DB00681Amphotericin B3Completed1
DB11633Isavuconazole3Completed2
DB06636Isavuconazonium3Completed2
DB01141Micafungin3Terminated1
DB01263Posaconazole3Completed1
DB00582Voriconazole3Completed2
DB01167Itraconazole4Completed1
DB00582Voriconazole4Completed1
DB00520CaspofunginNot AvailableCompleted1
DB00520CaspofunginNot AvailableEnrolling by Invitation1
DB06636IsavuconazoniumNot AvailableActive Not Recruiting1
DB01141MicafunginNot AvailableCompleted3
DB01263PosaconazoleNot AvailableActive Not Recruiting1
DB00582VoriconazoleNot AvailableActive Not Recruiting1
DB00582VoriconazoleNot AvailableCompleted1
DB00582VoriconazoleNot AvailableTerminated1