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Displaying drugs 1 - 25 of 13768 in total
Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Approved
Investigational
Matched Synonyms: … Indium In 111 Pentreotide ... Indium In 111 pentetreotide ... Indium In-111 pentetreotide …
Matched Name: … Indium In-111 pentetreotide …
Matched Iupac: … (111In)indium(3+) ion 2-{[2-({[(1-{[10-(4-aminobutyl)-16-benzyl-4-[(1,3-dihydroxybutan-2-yl)-C-hydroxycarbonimidoyl ... oxido-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaen-19-yl]-C-hydroxycarbonimidoyl}-2- …
Matched Description: … Indium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS …
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Synonyms: … Exon 53 specific antisense morpholino oligonucleotide …
Matched Description: … mutations allows for exon skipping, which retains a productive reading frame and results in the production ... [A218171, A218176, A218191] The application of antisense oligonucleotides in DMD patients with specific ... dystrophin levels in skeletal muscle of patients treated with viltolarsen; this approval is contingent …
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Synonyms: … Pkr-in-1 …
Matched Description: … Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy ... It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival ... of red blood cells. …
Matched Categories: … combinations of sulfonamides ... Heterocyclic Compounds, 2-Ring …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B Surface Antigen (rDNA) …
Matched Description: … In Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their ... 6 to14 years following a nationwide hepatitis B vaccination in Taiwan. ... The incubation period may be as long as 6 months, followed by a very complex clinical course of an acute …
Matched Products: … HEPAVAX-GENE TF INJ. ... วัคซีนป้องกันโรคตับอักเสบบี (rDNA) สำหรับเด็ก ... SII Hepatitis-B Vaccine (rDNA)(Adult)-Single Dose 1ml …
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe ... Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent ... [A232955] Other types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase …
Secretin porcine stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.
Approved
Matched Synonyms: … Secretin (swine) …
Matched Description: … Secretin porcine stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine ... dysfunction and the diagnosis of gastrinoma. …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, EC=3.5.4.4)-(1-356)-PEPTIDE PRODUCED IN ... ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES ... COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN …
Matched Description: … can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in ... cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … editing consisting of a guide RNA (gRNA) ... Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene
Matched Description: … [L49231] It is the first CRISPR-based gene editing therapy to be approved in the United States. ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease ... It was approved by the FDA in December 2023 for the treatment of patients with SCD with recurrent vaso-occlusive …
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Synonyms: … Milk of magnesia …
Matched Iupac: … magnesium(2+) dihydroxide …
Matched Description: … It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). ... Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable …
Matched Mixtures name: … Maalox oral suspension in sachet ... ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADET ... Milk Of Magnesia Mineral Oil Emulsion …
Matched Products: … Milk of Magnesia ... Milk Of Magnesia ... Milk of Magnesia Mint …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Synonyms: … Acetate of lime ... Brown acetate of lime ... Gray acetate of lime …
Matched Description: … It has been commonly referred to as the acetate of lime. ... The chemical compound calcium acetate is the calcium salt of acetic acid. …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Compounds used in a research, industrial, or household setting …
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Synonyms: … Chloride of potash ... Muriate of potash …
Matched Description: … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia ... , in buffer solutions, and in fertilizers and explosives. ... forms and those products formulated for preparation of solution prior to ingestion. …
Matched Mixtures name: … Volulyte 6 % Infusionslösung ... VOLULYTE 6% SOLUTION FOR INFUSION ... Volulyte Solution for Infusion 6% …
Matched Products: … CLORURO DE POTASIO 2 MEQ/ML ... TURKTIPSAN POTASYUM KLORÜR 10 MG/2 ML AMPUL, 10 ADET ... TURKTIPSAN POTASYUM KLORÜR 10 MG/2 ML AMPUL, 100 ADET …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... the virus) which results in an immunological defense against future exposure to the virus, or "antigen ... A seasonally-specific component of the influenza vaccine. …
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Synonyms: … Spirits of gum turpentine …
Matched Description: … It is used as a solvent and base material in organic synthesis reactions. ... Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted ... amounts of carene, camphene, dipentene, and terpinolene. …
Matched Salts cas: … 8006-64-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … Parathyroid hormone (rDNA) …
Matched Description: … Preotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic ... fractures and is marketed in Europe by Nycomed. ... Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. …
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … Lenograstim rDNA
Esculin is found in barley. Vitamin C2 is generally considered a bioflavanoid, related to vitamin P esculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum), California Buckeye (Aesculus californica) and in daphnin (the dark green resin of Daphne mezereum). Esculin belongs to the family of Glycosyl...
Approved
Matched Synonyms: … 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one ... Esculetin 6-O-glucoside ... esculetin 6-β-D-glucoside …
Matched Iupac: … 7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Description: … (the dark green resin of Daphne mezereum). ... Esculin belongs to the family of Glycosyl Compounds. ... Esculin is found in barley. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Approved
Experimental
Matched Synonyms: … Oil of cade ... Oil of juniper tar …
Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils . The acute sore throat (pharyngitis)...
Approved
Matched Synonyms: … 5-methyl-2-pentylphenol ... 6-amyl-m-cresol ... 6-n-amyl-m-cresol …
Matched Iupac: … 5-methyl-2-pentylphenol …
Matched Description: … Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the ... symptoms, and are increasingly important in the management of this condition [A32787]. ... in the primary care setting. …
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Synonyms: … 6-alpha-methylprednisone …
Matched Iupac: … (1R,3aS,3bS,5S,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H, …
Matched Description: … Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal …
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … in part, by IL-6, including increased production of anti-aquaporin-4 (AQP4) autoantibodies and increased ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive ... 6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on …
Matched Categories: … Interleukin-6 Receptor Antagonist …
Matched Products: … ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1ML ... ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringe …
Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Synonyms: … (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol …
Matched Iupac: … (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Description: … However, all Neupro patches in the United States and some of Europe were recalled in 2008 due to delivery ... In 1998 Aderis licensed worldwide development and commercialization rights to Schwarz Pharma of Germany ... over the course of 24 hours. …
Matched Salts cas: … 125572-93-2
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … NEUPRO® 6 MG/24 H ... นิวโปร 6 มก./24 ชม. แผ่นปิดผิวหนัง ... NEUPRO TRANSDERMAL PATCH 6 mg/24 hours …
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 2,4-Diamino-6-piperidinopyrimidine 3-oxide ... 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide …
Matched Description: … peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Products: … Yumhon 6% Minoxidil ... PILOGÁN® GEL 2% ... PILOGAN CREMA 2% …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Synonyms: … 6-Chloro-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[1,2,4]thiadiazine-7-sulfonic acid amide ... 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide …
Matched Iupac: … 6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... combinations of sulfonamides …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (S)-2-(6-Methoxy-2-naphthyl)propanoic acid ... (S)-2-(6-Methoxy-2-naphthyl)propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Description: … sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing ... overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of ... [A179098] Naproxen is available in both immediate and delayed release formulations, in combination with …
Matched Salts cas: … 26159-34-2
Matched Categories: … Non COX-2 selective NSAIDS …
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Synonyms: … 4-(6-Methoxy-2-naphthyl)-2-butanone ... 4-(6-Methoxy-2-naphthalenyl)-2-butanone …
Matched Iupac: … 4-(6-methoxynaphthalen-2-yl)butan-2-one …
Matched Description: … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone ... [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Displaying drugs 1 - 25 of 13768 in total