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Identification
NamePotassium Chloride
Accession NumberDB00761  (APRD01322)
TypeSmall Molecule
GroupsApproved, Withdrawn
DescriptionA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Structure
Thumb
Synonyms
[KCl]
Chlorid draselny
Chloride of potash
Kaliumchlorid
Kaon-CL 10
KCl
Klor-CON
Klotrix
Monopotassium chloride
Muriate of potash
Sylvite
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
K + 45Liquid251.6 gHemodialysisBaxter Laboratories1990-12-31Not applicableCanada
K C1-rougierLiquid750 mgOralRougier Pharma Division Of Ratiopharm Inc1967-12-311999-09-27Canada
K Lor Granules 20meqPowder, for solution1.5 gOralAbbott1979-12-312008-06-06Canada
K-durTablet, extended release1.5 gOralMerck Ltd.1989-12-312014-12-04Canada
K-lyte ClPowder, for solution1.86 gOralWell Spring Pharmaceutical Corporation1995-12-312009-02-23Canada
K-med 900 Tab 900mgTablet900 mgOralLaboratoire Riva Inc1989-12-312008-07-30Canada
K-tabTablet, film coated, extended release1500 mg/1OralAbbvie1980-06-09Not applicableUs
K-tabTablet, film coated, extended release750 mg/1OralAphena Pharma Solutions Tennessee, Inc.1980-06-09Not applicableUs
K-tabTablet, film coated, extended release600 mg/1OralAbbvie1980-06-09Not applicableUs
K-tabTablet, film coated, extended release750 mg/1OralAbbvie1980-06-09Not applicableUs
K-tabTablet, film coated, extended release750 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
K-tabTablet, film coated, extended release750 mg/1OralRemedy Repack2017-02-14Not applicableUs
Kalium Durules Srt 750mgTablet, extended release750 mgOralAstra Pharma Inc.1979-12-312001-07-23Canada
Kaochlor-10Solution10 %OralPfizer1995-12-312006-08-02Canada
Kato Pws 1.5gmPowder, for solution1.5 gOralIcn Pharmaceuticals1985-12-311998-08-13Canada
Kcl Solution A 20%Solution200 mgOralRougier Pharma Division Of Ratiopharm Inc1979-12-311999-09-27Canada
Klor-conTablet, film coated, extended release750 mg/1OralMckesson Rxpak Inc2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralCardinal Health1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralAphena Pharma Solutions Tennessee, Inc.1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralLegacy Pharmaceutical Packaging1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralCardinal Health2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralSandoz2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralPd Rx Pharmaceuticals, Inc.1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralAphena Pharma Solutions Tennessee, Inc.1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralLegacy Pharmaceutical Packaging1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralRemedy Repack2013-03-182016-11-15Us
Klor-conTablet, film coated, extended release750 mg/1OralSandoz2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralLiberty Pharmaceuticals, Inc.1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralAphena Pharma Solutions Tennessee, Inc.2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralMckesson Rxpak Inc2014-09-01Not applicableUs
Klor-conTablet, film coated, extended release750 mg/1OralCardinal Health1986-04-17Not applicableUs
Klor-conTablet, film coated, extended release600 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Klor-con Extended-releaseTablet, extended release600 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Klor-con Extended-releaseTablet, extended release750 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Klor-con Extended-releaseTablet, extended release750 mg/1OralContract Pharmacy Services Pa1986-04-17Not applicableUs
Micro K Extencaps Src 600mgCapsule, extended release600 mgOralAyerst Laboratories1991-12-311996-09-10Canada
Micro-K 10 ExtencapsCapsule, extended release750 mg/1OralTher Rx Corporation2009-08-01Not applicableUs
Micro-K ExtencapsCapsule, extended release600 mg/1OralTher Rx Corporation2009-08-01Not applicableUs
Novo-lente K Tab 600mgTablet, extended release600 mgOralNovopharm Limited1983-12-312005-08-10Canada
Potassium ChlorideTablet, film coated, extended release750 mg/1OralBlenheim Pharmacal, Inc.2013-11-13Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralPhysicians Total Care, Inc.1996-10-01Not applicableUs
Potassium ChlorideSolution40 meq/15mLOralLehigh Valley Technologies, Inc.2015-02-15Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralProficient Rx LP2011-02-22Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralA S Medication Solutions1986-04-17Not applicableUs
Potassium ChlorideTablet, extended release600 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Potassium ChlorideSolution40 meq/15mLOralQualitest2015-05-04Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1Oralbryant ranch prepack1986-04-17Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralAmerincan Health Packaging2015-03-312017-01-25Us
Potassium ChlorideTablet, film coated, extended release750 mg/1OralNucare Pharmaceuticals, Inc.2011-02-22Not applicableUs
Potassium ChlorideSolution20 meq/15mLOralAtlantic Biologicals Corp.2017-02-01Not applicableUs
Potassium ChlorideTablet, film coated, extended release1500 mg/1OralA S Medication Solutions2014-01-16Not applicableUs
Potassium ChlorideInjection, solution22.4 g/1000mLIntravenousBaxter Laboratories1989-12-26Not applicableUs
Potassium ChlorideInjection, solution30 meq/100mLIntravenousHospira, Inc.1992-11-30Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralTYA Pharmaceuticals2011-02-22Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralClinical Solutions Wholsesale1986-04-17Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1OralZydus Pharmaceuticals Usa, Inc.2010-10-25Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralSandoz1986-04-17Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralRemedy Repack2013-02-282016-11-01Us
Potassium ChlorideTablet, film coated, extended release750 mg/1OralA S Medication Solutions2011-02-22Not applicableUs
Potassium ChloridePowder, for solution1.5 g/1.58gOralQualitest2015-09-18Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralRemedy Repack2012-09-212016-12-28Us
Potassium ChlorideTablet, film coated, extended release750 mg/1Oralbryant ranch prepack2011-02-22Not applicableUs
Potassium ChlorideTablet, film coated, extended release1500 mg/1OralZydus Pharmaceuticals Usa, Inc.2014-01-16Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralRemedy Repack2014-08-05Not applicableUs
Potassium ChlorideTablet, film coated, extended release1500 mg/1OralDirectrx2014-01-01Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralA S Medication Solutions2014-01-16Not applicableUs
Potassium ChlorideInjection, solution7.46 g/1000mLIntravenousBaxter Laboratories1989-12-26Not applicableUs
Potassium ChlorideInjection, solution400 meq/1000mLIntravenousHospira, Inc.1992-11-30Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralLake Erie Medical Dba Quality Care Produts Llc2011-02-22Not applicableUs
Potassium ChlorideSolution20 meq/15mLOralLehigh Valley Technologies, Inc.2015-02-15Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralRemedy Repack2016-12-13Not applicableUs
Potassium ChlorideTablet, extended release600 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralSandoz1986-04-17Not applicableUs
Potassium ChlorideInjection, solution29.8 g/1000mLIntravenousBaxter Laboratories1989-12-26Not applicableUs
Potassium ChlorideInjection, solution10 meq/100mLIntravenousHospira, Inc.1992-11-30Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralCardinal Health1986-04-17Not applicableUs
Potassium ChlorideSolution20 meq/15mLOralVista Pharm, Inc.2015-02-15Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralRemedy Repack2011-04-202017-09-27Us
Potassium ChlorideSolution20 meq/15mLOralAtlantic Biologicals Corps.2015-05-04Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-10-25Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralRemedy Repack2013-11-122016-12-24Us
Potassium ChlorideTablet, film coated, extended release750 mg/1OralZydus Pharmaceuticals Usa, Inc.2011-02-22Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralSt. Marys Medical Park Pharmacy2013-05-15Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralAmerincan Health Packaging2012-07-02Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralPreferreed Pharmaceuticals Inc.2016-10-24Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralRemedy Repack2012-12-10Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralNesher Pharmaceuticals (USA) LLC2010-10-25Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralA S Medication Solutions1986-04-17Not applicableUs
Potassium ChloridePowder, for solution1.5 g/1.58gOralLehigh Valley Technologies, Inc.2015-09-07Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralMc Kesson Contract Packaging2013-04-15Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralUpsher Smith Laboratories1986-04-17Not applicableUs
Potassium ChlorideTablet, film coated, extended release1500 mg/1OralMajor2014-01-16Not applicableUs
Potassium ChlorideSolution40 meq/30mLOralVista Pharm, Inc.2015-02-15Not applicableUs
Potassium ChlorideInjection, solution14.9 g/1000mLIntravenousBaxter Laboratories1989-12-26Not applicableUs
Potassium ChlorideInjection, solution200 meq/1000mLIntravenousHospira, Inc.1992-11-30Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralAidarex Pharmaceuticals LLC1986-04-17Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralClinical Solutions Wholsesale1986-04-17Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralZydus Pharmaceuticals Usa, Inc.2010-10-25Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-10-25Not applicableUs
Potassium ChlorideTablet, film coated, extended release600 mg/1OralZydus Pharmaceuticals Usa, Inc.2014-01-16Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralSt. Marys Medical Park Pharmacy2014-08-20Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralAmerincan Health Packaging2011-09-13Not applicableUs
Potassium ChlorideTablet, film coated, extended release750 mg/1OralDirectrx2014-01-01Not applicableUs
Potassium ChlorideSolution20 meq/15mLOralQualitest2015-05-04Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1OralNesher Pharmaceuticals (USA) LLC2010-10-25Not applicableUs
Potassium Chloride Bp - Additive for Concentrated Haemodialysis SolutionsPowder15.26 gHemodialysisGenpharm Ulc1998-06-182004-07-30Canada
Potassium Chloride Bp - Additive for Concentrated Haemodialysis SolutionsPowder13 gHemodialysisGenpharm Ulc1998-06-182004-07-30Canada
Potassium Chloride Bp - Additive for Concentrated Haemodialysis SolutionsPowder12.5 gHemodialysisGenpharm Ulc1998-06-182004-07-30Canada
Potassium Chloride Bp - Additive for Concentrated Haemodialysis SolutionsPowder25 gHemodialysisGenpharm Ulc1998-06-222004-07-30Canada
Potassium Chloride Bp - Additive for Concentrated Haemodialysis SolutionsPowder7.65 gHemodialysisGenpharm Ulc1998-06-182004-07-30Canada
Potassium Chloride ERTablet, film coated, extended release750 mg/1OralNorthwind Pharmaceuticals2014-01-21Not applicableUs
Potassium Chloride for Injection ConcentrateSolution149 mgIntravenousHospira, Inc.1951-12-31Not applicableCanada
Potassium Chloride for Injection Concentrate, USP (2 Meq/ml)Solution2 meqIntravenousBaxter Laboratories1997-07-102011-05-10Canada
Potassium Chloride for Oral SolutionPowder, for solution1.5 g/1.58gOralVirtus Pharmaceuticals2017-01-09Not applicableUs
Potassium Chloride InjSolution20 meqIntravenousOmega Laboratories Ltd1978-12-31Not applicableCanada
Potassium Chloride Inj 149mg/ml USPLiquid149 mgIntravenousSabex Inc1970-12-312008-08-07Canada
Potassium Chloride Inj 149mg/ml USPLiquid149 mgIntravenousAyerst Laboratories1985-12-311996-09-10Canada
Potassium Chloride Inj 2meq/mlLiquid2 meqIntravenousInternational Medication Systems, Limited1971-12-311997-08-15Canada
Potassium Chloride Inj 30meqSolution1.784 mgIntravenousAbbott1951-12-312008-06-06Canada
Potassium Chloride Inj 40meqSolution2.384 mgIntravenousAbbott1951-12-312009-12-14Canada
Potassium Chloride Inj USP Liq 149mg/mlLiquid149 mgIntravenousWyeth Ayerst Canada Inc.1994-12-311997-01-14Canada
Potassium Chloride InjectionLiquid7.46 mgIntravenousBaxter Laboratories2000-08-10Not applicableCanada
Potassium Chloride InjectionLiquid22.4 mgIntravenousBaxter Laboratories2000-08-102011-05-10Canada
Potassium Chloride InjectionLiquid14.9 mgIntravenousBaxter Laboratories2000-08-10Not applicableCanada
Potassium Chloride InjectionLiquid29.8 mgIntravenousBaxter Laboratories2000-08-10Not applicableCanada
Potassium Chloride Injection 2meq/mlSolution2 meqIntravenousAstra Zeneca1985-12-312007-01-16Canada
Potassium SR 600mg TabletsTablet, extended release600 mgOralLaboratoires Confab IncNot applicableNot applicableCanada
Potassium-36.8 0.5-4.5 (code:k-30) - PowderPowder6.2 gHemodialysisBio Pharm, Inc.1995-12-311997-04-10Canada
Pro-600k Srt 600mgTablet, extended release600 mgOralPro Doc Limitee1984-12-312013-07-15Canada
Roychlor - 10% - Liq OrlLiquid10 %OralWaymar Pharmaceuticals Inc.1996-12-312004-07-01Canada
Slo-potTablet, extended release600 mgOralBiomed Pharma1982-12-31Not applicableCanada
Slow KTablet, extended release600 mgOralNovartis1970-12-312013-02-25Canada
Strong Potass Chloride Inj 0.15gm/mlLiquid150 mgIntravenousAnpharm Inc. C/O Stikeman Elliott1992-12-311997-02-17Canada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Klor Con MTablet, extended release1500 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs1998-11-20Not applicableUs
Klor Con MTablet, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs1998-11-20Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralRemedy Repack2011-09-262016-11-08Us
Klor-con MTablet, extended release750 mg/1OralUpsher Smith Laboratories2011-01-18Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralMc Kesson Contract Packaging2011-12-05Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-09-01Not applicableUs
Klor-con MTablet, extended release750 mg/1OralAphena Pharma Solutions Tennessee, Inc.2011-01-18Not applicableUs
Klor-con MTablet, extended release1125 mg/1OralUpsher Smith Laboratories2011-01-18Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralUpsher Smith Laboratories2011-01-18Not applicableUs
Klor-con MTablet, extended release20 meq/1OralPd Rx Pharmaceuticals, Inc.2011-01-18Not applicableUs
Klor-con MTablet, extended release750 mg/1OralSandoz2014-09-01Not applicableUs
Klor-con MTablet, extended release750 mg/1OralMc Kesson Contract Packaging2011-12-07Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralAphena Pharma Solutions Tennessee, Inc.2011-01-18Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralCardinal Health2014-09-01Not applicableUs
Klor-con MTablet, extended release1125 mg/1OralSandoz2014-09-01Not applicableUs
Klor-con MTablet, extended release10 meq/1OralCardinal Health2011-01-182015-12-29Us
Klor-con MTablet, extended release1500 mg/1OralAphena Pharma Solutions Tennessee, Inc.2014-09-01Not applicableUs
Klor-con MTablet, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-09-01Not applicableUs
Klor-con MTablet, extended release750 mg/1OralCardinal Health2014-09-01Not applicableUs
Klor-con MTablet, extended release1500 mg/1OralSandoz2014-09-01Not applicableUs
Klor-con MTablet, extended release750 mg/1OralAphena Pharma Solutions Tennessee, Inc.2014-09-01Not applicableUs
Klor-con M10Tablet, extended release10 meq/1OralApace Packaging2000-08-09Not applicableUs
Klor-con M10Tablet, extended release750 mg/1OralCardinal Health2011-01-18Not applicableUs
Klor-con M20Tablet, extended release1500 mg/1OralCardinal Health2011-01-18Not applicableUs
Klor-con M20Tablet, extended release20 meq/1OralApace Packaging2000-08-09Not applicableUs
Klor-con SprinkleCapsule, extended release600 mg/1OralSandoz2015-07-10Not applicableUs
Klor-con SprinkleCapsule, extended release750 mg/1OralSandoz2015-07-10Not applicableUs
Klor-con SprinkleCapsule, extended release600 mg/1OralUpsher Smith Laboratories2015-07-10Not applicableUs
Klor-con SprinkleCapsule, extended release750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2015-07-10Not applicableUs
Klor-con SprinkleCapsule, extended release750 mg/1OralUpsher Smith Laboratories2015-07-10Not applicableUs
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousHospira, Inc.1972-03-16Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralCardinal Health1998-11-20Not applicableUs
Potassium ChlorideInjection, solution, concentrate2 meq/mLIntravenousAPP Pharmaceuticals, Inc.2000-09-05Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralBlue Point Laboratories2013-06-23Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralProficient Rx LP2004-08-18Not applicableUs
Potassium ChlorideCapsule, extended release10 meq/1OralTris Pharma, Inc.2016-07-012016-11-30Us
Potassium ChlorideTablet, extended release20 meq/1OralPreferreed Pharmaceuticals Inc.2016-10-24Not applicableUs
Potassium ChlorideCapsule750 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2008-06-02Not applicableUs
Potassium ChlorideTablet, film coated, extended release10 meq/1OralMylan Institutional2015-04-30Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralPhysicians Total Care, Inc.2004-12-17Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralSt. Marys Medical Park Pharmacy2013-05-16Not applicableUs
Potassium ChlorideCapsule, coated, extended release8 meq/1OralLupin Pharmaceuticals2016-01-18Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralAv Kare, Inc.2014-05-07Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralA S Medication Solutions1998-11-20Not applicableUs
Potassium ChlorideInjection, solution, concentrate2 meq/mLIntravenousGeneral Injectables & Vaccines2010-08-01Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralAv Kare, Inc.2013-03-05Not applicableUs
Potassium ChlorideTablet, extended release8 meq/1OralNovel Laboratories, Inc.2016-08-09Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralAmneal Pharmaceuticals of New York Llc2013-02-22Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralRebel Distributors2002-04-10Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1OralPaddock Laboratories, Inc.2011-06-03Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralPd Rx Pharmaceuticals, Inc.2002-04-10Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralAmneal Pharmaceuticals2013-02-22Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralActavis Pharma Company2002-04-10Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralContract Pharmacy Services Pa2010-08-02Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralNovel Laboratories, Inc.2016-01-21Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralGlenmark Pharmaceuticals Inc.,Usa2016-07-26Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1Oralbryant ranch prepack1998-11-20Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralCardinal Health2009-08-10Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralBlenhiem Pharmacal, Inc.2013-10-02Not applicableUs
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousHospira, Inc.1972-03-16Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1Oralbryant ranch prepack2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralAmerincan Health Packaging2010-01-21Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralSandoz1998-11-20Not applicableUs
Potassium ChlorideCapsule, extended release8 meq/1OralTris Pharma, Inc.2016-07-012016-11-30Us
Potassium ChlorideTablet, extended release750 mg/1OralA S Medication Solutions1998-11-20Not applicableUs
Potassium ChlorideCapsule, extended release8 meq/1OralVensun Pharmaceuticals, Inc.2015-12-08Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralPhysicians Total Care, Inc.2002-04-19Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralRemedy Repack2015-12-14Not applicableUs
Potassium ChlorideCapsule, coated, extended release10 meq/1OralLupin Pharmaceuticals2016-01-18Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralUnit Dose Services2004-08-18Not applicableUs
Potassium ChlorideCapsule, coated, extended release8 meq/1OralLupin Pharmaceuticals2016-01-18Not applicableUs
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousGeneral Injectables & Vaccines2015-11-16Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralUnit Dose Services1998-11-20Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralNovel Laboratories, Inc.2016-08-09Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralNucare Pharmaceuticals, Inc.2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralRebel Distributors2002-04-10Not applicableUs
Potassium ChlorideTablet, extended release600 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralPaddock Laboratories, Inc.2011-06-03Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralCardinal Health2010-01-21Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralActavis Pharma Company2002-04-10Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralLake Erie Medical Dba Quality Care Produts Llc2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2002-04-10Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralA S Medication Solutions2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralNucare Pharmaceuticals, Inc.2004-08-18Not applicableUs
Potassium ChlorideTablet, film coated, extended release10 meq/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-08-21Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralSafecor Health, LLC2014-09-30Not applicableUs
Potassium ChlorideInjection, solution, concentrate14.9 g/100mLParenteralB. Braun Medical Inc.1978-03-21Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralRemedy Repack2013-09-272017-01-10Us
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousHospira, Inc.1972-03-16Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralMc Kesson Packaging Services A Buisness Unit Of Mc Kesson Corporation2009-08-03Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralAmerincan Health Packaging2013-01-18Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralSandoz1998-11-20Not applicableUs
Potassium ChlorideCapsule, extended release8 meq/1OralNovel Laboratories, Inc.2016-08-15Not applicableUs
Potassium ChlorideTablet, film coated, extended release8 meq/1OralMylan Pharmaceuticals2014-08-21Not applicableUs
Potassium ChlorideCapsule, coated, extended release10 meq/1OralLupin Pharmaceuticals2016-01-18Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralA S Medication Solutions2002-04-10Not applicableUs
Potassium ChlorideCapsule, extended release10 meq/1OralVensun Pharmaceuticals, Inc.2015-12-08Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1OralActavis Pharma Company2008-08-25Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralContract Pharmacy Services Pa2010-08-02Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralGlenmark Pharmaceuticals Inc.,Usa2016-01-20Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralCardinal Health2009-08-25Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralPd Rx Pharmaceuticals, Inc.2004-08-18Not applicableUs
Potassium ChlorideInjection149 mg/mLIntravenousCardinal Health1972-03-16Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralRemedy Repack2013-10-072016-11-02Us
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousPhysicians Total Care, Inc.2007-03-16Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralCardinal Health1998-11-20Not applicableUs
Potassium ChlorideInjection, solution, concentrate2 meq/mLIntravenousAPP Pharmaceuticals, Inc.1999-09-27Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralBlue Point Laboratories2014-02-25Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralAv Pak2016-01-28Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralMajor2009-08-25Not applicableUs
Potassium ChlorideTablet, film coated, extended release10 meq/1OralA S Medication Solutions2014-08-21Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralSafecor Health, LLC2014-09-30Not applicableUs
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousHospira, Inc.1972-03-162016-10-13Us
Potassium ChlorideCapsule, extended release10 meq/1OralNovel Laboratories, Inc.2016-08-15Not applicableUs
Potassium ChlorideTablet, film coated, extended release10 meq/1OralMylan Pharmaceuticals2014-08-21Not applicableUs
Potassium ChlorideInjection2 meq/mLIntravenousGeneral Injectables & Vaccines2010-08-01Not applicableUs
Potassium ChlorideInjection, solution, concentrate149 mg/mLIntravenousHospira, Inc.1972-03-16Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralPd Rx Pharmaceuticals, Inc.2008-08-25Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralMc Kesson Packaging Services A Buisness Unit Of Mc Kesson Corporation2009-08-10Not applicableUs
Potassium ChlorideCapsule, extended release8 meq/1OralCarilion Materials Management2008-08-25Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1OralAv Kare, Inc.2013-03-05Not applicableUs
Potassium ChlorideTablet, extended release10 meq/1OralNovel Laboratories, Inc.2016-01-21Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralActavis Pharma Company2004-08-18Not applicableUs
Potassium ChlorideTablet, extended release750 mg/1OralGlenmark Pharmaceuticals Inc.,Usa2016-07-26Not applicableUs
Potassium ChlorideCapsule, extended release600 mg/1Oralbryant ranch prepack2011-06-03Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralAphena Pharma Solutions Tennessee, Inc.2004-08-18Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralActavis Pharma Company2008-08-25Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralContract Pharmacy Services Pa2010-08-02Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralClinical Solutions Wholsesale2004-08-18Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralBlue Point Laboratories2013-12-022015-10-31Us
Potassium ChlorideInjection149 mg/mLIntravenousCardinal Health1972-03-16Not applicableUs
Potassium ChlorideTablet, extended release1500 mg/1OralRemedy Repack2017-01-19Not applicableUs
Potassium ChlorideTablet, extended release20 meq/1OralAidarex Pharmaceuticals LLC2002-04-10Not applicableUs
Potassium ChlorideCapsule, extended release750 mg/1OralPhysicians Total Care, Inc.1996-04-11Not applicableUs
Potassium Chloride ERTablet20 meq/1OralNorthwind Pharmaceuticals2014-10-22Not applicableUs
Potassium Chloride Extended ReleaseTablet, extended release600 mg/1OralPaddock Laboratories, Inc.2015-12-11Not applicableUs
Potassium Chloride Extended ReleaseTablet, extended release750 mg/1OralPaddock Laboratories, Inc.2015-12-11Not applicableUs
Potassium Chloride Extended-releaseCapsule, extended release10 meq/1OralPar Pharmaceutical2013-12-26Not applicableUs
Potassium Chloride Extended-releaseCapsule, extended release8 meq/1OralPar Pharmaceutical2013-12-26Not applicableUs
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Hi Potency Potassium ChlorideTablet, extended release500 mgOralSwiss Herbal Remedies Ltd.1997-02-242001-08-02Canada
Kaochlor-20Solution3 gOralPfizer1995-12-312006-08-02Canada
Micro-K-10 Extencaps Src 750mgCapsule, extended release750 mgOralWyeth Ayerst Canada Inc.1994-12-312003-07-28Canada
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Humco Potassium Chloride Oral Solution 10%Liquid100 mg/mLOralHumco Holding Group. Inc.1979-01-012016-10-13Us
K-solLiquid20 meq/15mLOralLaser Pharmaceuticals Llc2015-01-222015-12-31Us
K-solLiquid40 meq/15mLOralLaser Pharmaceuticals Llc2015-01-222015-12-31Us
Klor-conPowder, for solution20 meq/1OralCardinal Health2009-11-01Not applicableUs
Klor-conPowder, for solution1.875 g/1OralUpsher Smith Laboratories2009-11-01Not applicableUs
Klor-conPowder, for solution1.5 g/1OralSandoz2014-09-01Not applicableUs
Klor-conPowder, for solution1.5 g/1OralUpsher Smith Laboratories2009-11-01Not applicableUs
Klor-con/25Powder, for solution1.875 g/1OralSandoz2014-09-01Not applicableUs
Potassium ChlorideSolution20 meq/15mLOralQualitest1996-08-012016-08-31Us
Potassium ChlorideSolution1.5 g/15mLOralPharmaceutical Associates, Inc.1969-01-012016-10-13Us
Potassium ChlorideLiquid40 meq/30mLOralRising Pharmaceuticals2013-09-232016-09-30Us
Potassium ChlorideSolution20 meq/15mLOralQualitest1997-04-012016-09-30Us
Potassium ChlorideSolution3 g/15mLOralPharmaceutical Associates, Inc.2014-10-01Not applicableUs
Potassium ChloridePowder, for solution1.5 g/1.74gOralCardinal Health2013-10-09Not applicableUs
Potassium ChlorideLiquid40 meq/15mLOralRising Pharmaceuticals2014-04-162016-09-30Us
Potassium ChlorideSolution40 meq/15mLOralQualitest1996-10-012016-08-31Us
Potassium ChlorideSolution1.5 g/15mLOralPharmaceutical Associates, Inc.1969-01-012016-10-13Us
Potassium ChlorideSolution1.5 g/15mLOralCardinal Health1969-01-01Not applicableUs
Potassium ChloridePowder, for solution1.5 g/1.74gOralAv Pak2015-06-032016-10-13Us
Potassium ChlorideSolution20 meq/15mLOralQualitest1996-10-01Not applicableUs
Potassium ChloridePowder, for solution25 meq/1OralVirtus Pharmaceuticals2014-06-13Not applicableUs
Potassium ChlorideSolution40 meq/30mLOralMajor2008-12-302016-03-11Us
Potassium ChloridePowder, for solution1.5 g/1.74gOralVirtus Pharmaceuticals Op Co Ii2013-10-09Not applicableUs
Potassium ChlorideSolution1.5 g/15mLOralCardinal Health1969-01-01Not applicableUs
Potassium ChloridePowder1.5 g/1.74gOralLibertas Pharma, Inc.2015-03-16Not applicableUs
Potrassium ChlorideSolution40 meq/30mLOralMajor2014-07-232015-12-29Us
International Brands
NameCompany
Kaon ClNot Available
KlotrixNot Available
Micro-KNot Available
Sando-KNot Available
Slow-KNot Available
Brand mixtures
NameLabellerIngredients
(20mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USPBaxter Laboratories
(40 Mmol/l) Potassium Chloride In 0.9% Sodium Chloride Injection USPBaxter Laboratories
(40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USPBaxter Laboratories
20 (meq)mmol/l Potassium Chloride In/et 0.9% Chlorure De Sodium/sodium Chloride Injection USPHospira, Inc.
40(meq)mmol/l Potassium Chloride In/et 0.9% Chlorure De Sodium/sodium Chloride Injection USPHospira, Inc.
Accusol 35 K2Chief Medical Supplies Ltd
Accusol 35 K4Chief Medical Supplies Ltd
Acid Concentrate D12028Althin Biopharm Inc.
Acid Concentrate D12054Althin Biopharm Inc.
Acid Concentrate D12092Althin Biopharm Inc.
Acid Concentrate D12093Baxter Laboratories
Acid Concentrate D12095Baxter Laboratories
Acid Concentrate D12119Althin Biopharm Inc.
Acid Concentrate D12132Althin Biopharm Inc.
Acid Concentrate D12150Althin Biopharm Inc.
Acid Concentrate D12247Althin Biopharm Inc.
Acid Concentrate D12250Althin Biopharm Inc.
Acid Concentrate D12261Althin Biopharm Inc.
Acid Concentrate D12268Althin Biopharm Inc.
Acid Concentrate (r04968)Genpharm Ulc
Acid Concentrate (r04969)Genpharm Ulc
Acid Concentrate (r04974)Genpharm Ulc
Acid Concentrate (r04975)Genpharm Ulc
Acid Concentrate (r04976)Genpharm Ulc
Acid Concentrate 2109Althin Biopharm Inc.
Acid Concentrate 2189Baxter Laboratories
Acid Concentrate 2196Althin Biopharm Inc.
Acid Concentrate 2198Baxter Laboratories
Acid Concentrate Bp Rz267cGenpharm Ulc
Acid Concentrate D-18006Baxter Laboratories
Acid Concentrate D12252Althin Biopharm Inc.
Acid Concentrate D12292Baxter Laboratories
Acid Concentrate D12315Althin Biopharm Inc.
Acid Concentrate D18001Althin Biopharm Inc.
Acid Concentrate D18009Althin Biopharm Inc.
Acid Concentrate Ro4947Genpharm Ulc
Acid Concentrate Rx252cBdh Inc.
Acid Concentrate Rx253cBdh Inc.
Acid Concentrate Rz110cGenpharm Ulc
Acid Concentrate Rz144cGenpharm Ulc
Acid Concentrate Rz211cGenpharm Ulc
Acid Concentrate Rz212cGenpharm Ulc
Acid Concentrate-r04948 LiqBdh Inc.
Acid Concentrate(36.83x) R04900Bdh Inc.
Acid Concentrate(36.83x) R04906Bdh Inc.
Adrenogist TabPure Life International Prods Inc.
AminosynHospira, Inc.
Aminosyn II 10% With ElectrolytesHospira, Inc.
Aminosyn II With ElectrolytesHospira, Inc.
Amo Endosol SolutionAmo Canada Company
Balanced SaltB. Braun Medical Inc.
Balanced Salt SolutionHospira, Inc.
Bi-peglytePendopharm Division Of De Pharmascience Inc
Bicarb Hemodial Conc 36.83Bicarbolyte Corporation
Bicarbolyte Bicar Hemodialsis ConcBicarbolyte Corporation
Bicarbolyte Bicar Hemodialysis ConcBicarbolyte Corporation
BssAlcon, Inc.
Bss PlusAlcon, Inc.
CardioplegicBaxter Laboratories
ColytePendopharm Division Of De Pharmascience Inc
Colyte With Flavor PacksAlaven Pharmaceutical
Concentrated Haemodialysis Solution Bp-rz266cGenpharm Ulc
D-12043 Sol Conc Electrolyt Pour DialyBio Pharm, Inc.
D12006Bio Pharm, Inc.
D12046 Conc Electrolyte Renal DialysisBio Pharm, Inc.
Dioptic's Balanced Salt SolutionDioptic Pharmaceuticals Inc
Effervescent Potassium ChlorideQualitest
Electropeg SolutionTechnilab Pharma Inc.
Elliott's Solution AHospira, Inc.
EyestreamAlcon, Inc.
Gavilyte - C TmGavis Pharmaceuticals, LLC.
Gavilyte - NGavis Pharmaceuticals, LLC.
Gavilyte G TmLupin Pharmaceuticals
Glycerolyte 57 SolutionFenwal, Inc.
GolytelyBraintree Laboratories
Golytely Gi Lavage SolutionBraintree Laboratories
Haemosol H-250Haemotec Inc.
Haemosol H-251Haemotec Inc.
Haemosol H-252Haemotec Inc.
Hemosol Lg2Gambro Inc
Hemosol Lg4Gambro Inc
Hyperlyte (multi-electrolyte Concentrate)B. Braun Medical Inc.
Iocare Balanced Salt SolutionIolab Pharmaceuticals
Isolyte SB. Braun Medical Inc.
Isolyte S (multi-electrolyte Injection)B. Braun Medical Inc.
Isolyte S Ph 7.4B. Braun Medical Inc.
IsoplateTerumo Bct
Jamp-electropegJamp Pharma Corporation
Jamp-electropeg With Flavour PacketJamp Pharma Corporation
JamplyteJamp Pharma Corporation
Jamplyte 280Jamp Pharma Corporation
K+36.8Baxter Laboratories
K2 Liq R04902Bdh Inc.
Klean-prepPendopharm Division Of De Pharmascience Inc
Lactated Ringer's InjectionHospira, Inc.
Lactated Ringer's Injection USPB. Braun Medical Inc.
Lactated Ringer's IrrigationHospira, Inc.
Lactated Ringer's Irrigation SolBaxter Laboratories
Lactated RingersB. Braun Medical Inc.
Lactated Ringers Inj USPBaxter Laboratories
Lactated Ringers IrrigationB. Braun Medical Inc.
LypholytePartners Health Care, Inc.
Lypholyte Multi-electrolyte Conc InjLyphomed, Division Of Fujisawa Canada Inc.
LyteprepTherapex Division De E Z Em Canada Inc
Moi-stir Oral SwabsticksSolvay Pharma Inc
Moi-stir SpraySolvay Pharma Inc
MoviprepMedical Futures Inc
Multiple Electrolyte Additive InjInternational Medication Systems, Limited
Multiple Electrolyte Additive Liq Formula 1Baxter Laboratories
Naturalyte H-251Fresenius Medical Care Korea
Naturalyte H-252Fresenius Medical Care Korea
Neo KNeolab Inc
Normosol RHospira, Inc.
Normosol-RHospira, Inc.
NulytelyPhysicians Total Care, Inc.
NutrilyteAmerican Regent
Ocl SolutionAbbott
Odan Balanced Salt SolutionOdan Laboratories Ltd
One A Day Advance AdultsBayer Inc Consumer Care
One A Day Advance Adults 50+Bayer Inc Consumer Care
Peg-3350 and ElectrolytesAffordable Pharmaceuticals, LLC
Peg-3350, Sodium Chloride, Sodium Bicarbonate and Potassium ChlorideAffordable Pharmaceuticals, LLC
Peglyte PowderPendopharm Division Of De Pharmascience Inc
Peglyte SolutionPharmascience Inc
Phoxillum Bk4/2.5Baxter Laboratories
PhysiolyteB. Braun Medical Inc.
PhysiosolHospira, Inc.
Plasma-lyte 148Baxter Laboratories
Plasma-lyte ABaxter Laboratories
Plasma-lyte A InjectionBaxter Laboratories
Plasmalyte 148 In WaterBaxter Laboratories
PlegisolHospira, Inc.
Polyethylene Glycol 3350 and ElectrolytesMylan Pharmaceuticals
Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride - UnflavoredStrides Shasun Limited
Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride With Lemon FlavorStrides Shasun Limited
Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride With Orange FlavorStrides Shasun Limited
Polyethylene Glycol-3350 and ElectrolytesNovel Laboratories, Inc.
Polyethylene Glycol-3350 and Electrolytes With Flavor PackNovel Laboratories, Inc.
Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium BicarbonateNovel Laboratories, Inc.
Potassium Chloride In Lactated Ringer's InjectionBaxter Laboratories
Potassium Chloride In Sodium ChlorideB. Braun Medical Inc.
Potassium Chloride In Sodium Chloride Injection USPBaxter Laboratories
Potassium-novartisNovartis
Prismasol 2Baxter Laboratories
Prismasol 4Baxter Laboratories
Prolax - PwsRivex Pharma Inc.
R04903 LiqBdh Inc.
R04909 LiqBdh Inc.
R04919 LiqBdh Inc.
R04922 LiqBdh Inc.
R04936 LiqBdh Inc.
R04946 LiqBdh Inc.
R04972 LiqBdh Inc.
R04973 LiqBdh Inc.
Ringer's InjBaxter Laboratories
Ringer's Injection USPB. Braun Medical Inc.
RingersB. Braun Medical Inc.
Salivart AerAll Star Sales and Service Ltd.
Salivart Oral MoisturizerGebauer Company
Sb 1000Renal Systems, Division Of Minntech Corp.
Sb-110Renal Systems, Division Of Minntech Corp.
Sb-131Renal Systems, Division Of Minntech Corp.
Sb-132Renal Systems, Division Of Minntech Corp.
Super Charged EnergySimone Protective Pharmaceuticals, Inc.
Tis-U-solBaxter Laboratories
Tpn ElectrolytesHospira, Inc.
Trilyte With Flavor PacksWallace Pharmaceuticals Inc.
Vamin NFresenius Kabi Ab
SaltsNot Available
Categories
UNII660YQ98I10
CAS number7447-40-7
WeightAverage: 74.551
Monoisotopic: 73.932559568
Chemical FormulaClK
InChI KeyWCUXLLCKKVVCTQ-UHFFFAOYSA-M
InChI
InChI=1S/ClH.K/h1H;/q;+1/p-1
IUPAC Name
potassium chloride
SMILES
[Cl-].[K+]
Pharmacology
IndicationFor use as an electrolyte replenisher and in the treatment of hypokalemia.
Structured Indications
PharmacodynamicsThe potassium ion is in the principle intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function. The intracellular concentration of potassium is approximately 150 to 160 mEq per liter. The normal adult plasma concentration is 3.5 to 5 mEq per liter. An active ion transport system maintains this gradient across the plasma membrane. Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. The usual dietary intake of potassium is 50 to 100 mEq per day. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops as a consequence of therapy with diuretics, primarily or secondary hyperaldosteronism, diabetic ketoacidosis, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Potassium depletion due to these causes is usually accompanied by concomitant loss of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and, in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. If potassium depletion associated with metabolic alkalosis cannot be managed by correcting the fundamental cause of the deficiency, e.g., where the patient requires long-term diuretic therapy, supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels. In rare circumstances (e.g., patients with renal tubular acidosis) potassium depletion may be associated with metabolic acidosis and hyperchloremia. In such patients, potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.
Mechanism of actionSupplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.
TargetKindPharmacological actionActionsOrganismUniProt ID
Solute carrier family 12 member 2ProteinunknownNot AvailableHumanP55011 details
Solute carrier family 12 member 1Proteinunknown
binder
HumanQ13621 details
Solute carrier family 12 member 5ProteinunknownNot AvailableHumanQ9H2X9 details
Solute carrier family 12 member 6ProteinunknownNot AvailableHumanQ9UHW9 details
Solute carrier family 12 member 7ProteinunknownNot AvailableHumanQ9Y666 details
Solute carrier family 12 member 4ProteinunknownNot AvailableHumanQ9UP95 details
Related Articles
AbsorptionPotassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine.
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationPotassium is a normal dietary constituent and, under steady-state conditions, the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake.
Half lifeNot Available
ClearanceNot Available
ToxicityThe administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, of if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result. It is important to recognize that hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-wave, depression of S-T segment, and prolongation of the QT interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L).
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
AclidiniumAclidinium may increase the ulcerogenic activities of Potassium Chloride.Approved
Anisotropine MethylbromideAnisotropine Methylbromide may increase the ulcerogenic activities of Potassium Chloride.Approved
Atracurium besylateAtracurium besylate may increase the ulcerogenic activities of Potassium Chloride.Approved
AtropineAtropine may increase the ulcerogenic activities of Potassium Chloride.Approved, Vet Approved
BenactyzineBenactyzine may increase the ulcerogenic activities of Potassium Chloride.Withdrawn
BenzatropineBenzatropine may increase the ulcerogenic activities of Potassium Chloride.Approved
BiperidenBiperiden may increase the ulcerogenic activities of Potassium Chloride.Approved
ChlorphenoxamineChlorphenoxamine may increase the ulcerogenic activities of Potassium Chloride.Withdrawn
CyclopentolateCyclopentolate may increase the ulcerogenic activities of Potassium Chloride.Approved
DarifenacinDarifenacin may increase the ulcerogenic activities of Potassium Chloride.Approved, Investigational
DesloratadineDesloratadine may increase the ulcerogenic activities of Potassium Chloride.Approved, Investigational
DexetimideDexetimide may increase the ulcerogenic activities of Potassium Chloride.Withdrawn
DicyclomineDicyclomine may increase the ulcerogenic activities of Potassium Chloride.Approved
EthopropazineEthopropazine may increase the ulcerogenic activities of Potassium Chloride.Approved
FesoterodineFesoterodine may increase the ulcerogenic activities of Potassium Chloride.Approved
Gallamine TriethiodideGallamine Triethiodide may increase the ulcerogenic activities of Potassium Chloride.Approved
GlycopyrroniumThe risk or severity of adverse effects can be increased when Glycopyrronium is combined with Potassium Chloride.Approved, Investigational, Vet Approved
HexamethoniumHexamethonium may increase the ulcerogenic activities of Potassium Chloride.Experimental
HomatropineHomatropine may increase the ulcerogenic activities of Potassium Chloride.Approved
HyoscyamineHyoscyamine may increase the ulcerogenic activities of Potassium Chloride.Approved
Ipratropium bromideIpratropium bromide may increase the ulcerogenic activities of Potassium Chloride.Approved
MecamylamineMecamylamine may increase the ulcerogenic activities of Potassium Chloride.Approved
MethanthelineMethantheline may increase the ulcerogenic activities of Potassium Chloride.Approved
MetixeneMetixene may increase the ulcerogenic activities of Potassium Chloride.Approved
N-butylscopolammonium bromideN-butylscopolammonium bromide may increase the ulcerogenic activities of Potassium Chloride.Vet Approved
NVA237NVA237 may increase the ulcerogenic activities of Potassium Chloride.Investigational
OrphenadrineOrphenadrine may increase the ulcerogenic activities of Potassium Chloride.Approved
OxybutyninOxybutynin may increase the ulcerogenic activities of Potassium Chloride.Approved, Investigational
OxyphenoniumOxyphenonium may increase the ulcerogenic activities of Potassium Chloride.Approved
PancuroniumPancuronium may increase the ulcerogenic activities of Potassium Chloride.Approved
PentoliniumPentolinium may increase the ulcerogenic activities of Potassium Chloride.Approved
PipecuroniumPipecuronium may increase the ulcerogenic activities of Potassium Chloride.Approved
PirenzepinePirenzepine may increase the ulcerogenic activities of Potassium Chloride.Approved
ProcyclidineProcyclidine may increase the ulcerogenic activities of Potassium Chloride.Approved
PropanthelinePropantheline may increase the ulcerogenic activities of Potassium Chloride.Approved
PropiverinePropiverine may increase the ulcerogenic activities of Potassium Chloride.Investigational
QuinidineQuinidine may increase the ulcerogenic activities of Potassium Chloride.Approved
ScopolamineScopolamine may increase the ulcerogenic activities of Potassium Chloride.Approved
Scopolamine butylbromideScopolamine butylbromide may increase the ulcerogenic activities of Potassium Chloride.Approved
SolifenacinSolifenacin may increase the ulcerogenic activities of Potassium Chloride.Approved
TiotropiumTiotropium may increase the ulcerogenic activities of Potassium Chloride.Approved
TolterodineTolterodine may increase the ulcerogenic activities of Potassium Chloride.Approved, Investigational
TrihexyphenidylTrihexyphenidyl may increase the ulcerogenic activities of Potassium Chloride.Approved
TrimethaphanTrimethaphan may increase the ulcerogenic activities of Potassium Chloride.Approved
TropicamideTropicamide may increase the ulcerogenic activities of Potassium Chloride.Approved
TrospiumTrospium may increase the ulcerogenic activities of Potassium Chloride.Approved
TubocurarineTubocurarine may increase the ulcerogenic activities of Potassium Chloride.Approved
UmeclidiniumUmeclidinium may increase the ulcerogenic activities of Potassium Chloride.Approved
VecuroniumVecuronium may increase the ulcerogenic activities of Potassium Chloride.Approved
Food Interactions
  • Take with a full glass of water Take after a full meal.
References
Synthesis Reference

Fritz Hagedorn, Gerd Peuschel, Arno Singewald, “Method for the production of potassium chloride with K.sub.2 O content of more than 55 weight percent.” U.S. Patent US5057208, issued July, 1955.

US5057208
General ReferencesNot Available
External Links
ATC CodesB05XA01A12BA51A12BA01
AHFS Codes
  • 40:12.00
  • 40:34.00*
  • 88:29.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (632 KB)
MSDSDownload (72.6 KB)
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedDiagnosticHuman Immunodeficiency Virus (HIV) Infections1
1CompletedTreatmentColorectal Cancers1
1CompletedTreatmentGastric Emptying / Healthy Volunteers1
1, 2CompletedSupportive CareHypertensive / Pre-Hypertension1
1, 2CompletedTreatmentAutism Spectrum Disorder (ASD) / Gastrointestinal Problems1
1, 2CompletedTreatmentArterial hypoxia / Hypotension1
2Active Not RecruitingTreatmentCardiopulmonary Bypass / Surgery, Cardiac1
2CompletedTreatmentAcidosis, Respiratory / Shock, Hemorrhagic / Traumatic Shock1
2CompletedTreatmentBlood Loss,Surgical / Carcinoma of the Prostate / General Surgery1
2CompletedTreatmentBone Diseases / Metabolic Acidosis / Mineral Metabolism / Physical Capacity / Renal Transplant Patients1
2CompletedTreatmentColon Cancer1
2CompletedTreatmentColonoscopy1
2CompletedTreatmentDiastolic Heart Failure / Heart Failure (HF)1
2CompletedTreatmentSymptomatic Focal Vitreomacular Adhesion1
2RecruitingNot AvailableBowel Cleansing1
2RecruitingPreventionHypertensive1
2RecruitingTreatmentHypertensive1
2RecruitingTreatmentNeoplasms, Brain1
2RecruitingTreatmentPain1
2, 3CompletedTreatmentGlaucoma1
3CompletedNot AvailableBowel Preparation for Colonoscopy1
3CompletedNot AvailableColonoscopy1
3CompletedDiagnosticBowel Preparation for Colonoscopy1
3CompletedDiagnosticBowel Preparation, Efficacy, Tolerability, Safety1
3CompletedSupportive CareColon Adenomas / Colorectal Cancers1
3CompletedTreatmentBowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel1
3CompletedTreatmentCardiovascular Diseases / Heart Diseases / Hypertensive1
3CompletedTreatmentCataracts2
3CompletedTreatmentColon Cancer1
3CompletedTreatmentColon Cancer / Colon Polyps / Colorectal Polyps / Crohn's Disease (CD) / Diverticulitis / Rectal Cancers / Ulcerative Colitis (UC)1
3CompletedTreatmentColon Diseases / Colonoscopy Preparation1
3CompletedTreatmentColonoscopy3
3CompletedTreatmentOccasional Constipation1
3RecruitingDiagnosticColonoscopy1
3RecruitingSupportive CareColonic Diseases / Diabetes Mellitus (DM)1
4Active Not RecruitingNot AvailableColonoscopy1
4Active Not RecruitingTreatmentArthrocentesis / Pain / Temporomandibular Joint Dysfunction1
4Active Not RecruitingTreatmentGraves' Ophthalmopathy1
4CompletedBasic ScienceFunctional Constipation / Irritable Bowel Syndrome Characterized by Constipation1
4CompletedPreventionInflammatory processes1
4CompletedScreeningColorectal Cancers1
4CompletedTreatmentBowel Preparation for Colonoscopy1
4CompletedTreatmentColon Cancer1
4CompletedTreatmentColonoscopy3
4CompletedTreatmentColorectal Cleansing Prior Operation1
4CompletedTreatmentCritically Ill / Surgery, Cardiac / Thoracic Surgery1
4CompletedTreatmentGastrointestinal Diseases1
4CompletedTreatmentPreparation for Colonoscopy1
4Not Yet RecruitingHealth Services ResearchColonoscopy1
4RecruitingTreatmentAtrial Flutter / Nonvalvular Atrial Fibrillation1
4RecruitingTreatmentSubjets Requiring a Colonoscopy1
4RecruitingTreatmentTraumas1
Not AvailableCompletedNot AvailableEffectiveness of SMS to Fix PC Interval1
Not AvailableCompletedNot AvailableHyponatremias1
Not AvailableCompletedNot AvailableSpinal Cord Injuries (SCI)1
Not AvailableCompletedNot AvailableThe Timing of Bowel Preparation in Outpatient Colonoscopy1
Not AvailableCompletedTreatmentCataracts1
Not AvailableCompletedTreatmentHepatic Encephalopathy / Liver Cirrhosis / Portosystemic Encephalopathy / PSE1
Not AvailableNot Yet RecruitingHealth Services ResearchAcute Kidney Injury (AKI)1
Not AvailableNot Yet RecruitingScreeningActual Impaired Fluid Volume1
Not AvailableRecruitingDiagnosticBowel Preparation for Colonoscopy1
Not AvailableRecruitingDiagnosticColonoscopy1
Not AvailableRecruitingDiagnosticDiabetes Mellitus (DM)1
Not AvailableRecruitingPreventionHypertensive1
Not AvailableTerminatedPreventionBlood Pressures1
Not AvailableWithdrawnScreeningPatients Undergoing Screening or Surveillance Colonoscopy1
Not AvailableWithdrawnTreatmentAltered Mental Status / AMS / HE / Hepatic Encephalopathy / Liver Cirrhosis1
Pharmacoeconomics
Manufacturers
  • Novo nordisk inc
  • Savage laboratories inc div altana inc
  • Kv pharmaceutical co
  • Teva pharmaceuticals usa inc
  • Watson laboratories inc florida
  • Abraxis pharmaceutical products
  • Akorn inc
  • App pharmaceuticals llc
  • B braun medical inc
  • Baxter healthcare corp anesthesia and critical care
  • Baxter healthcare corp
  • Gd searle llc
  • Hospira inc
  • International medication system
  • Eli lilly and co
  • Luitpold pharmaceuticals inc
  • Miles laboratories inc
  • Pharma serve inc sub torigian laboratories
  • Watson laboratories inc
  • Future pak ltd
  • Upsher smith laboratories inc
  • Apothecon inc div bristol myers squibb
  • Abbott laboratories pharmaceutical products div
  • Copley pharmaceutical inc
  • Eurand america inc
  • Schering corp
  • Novartis pharmaceuticals corp
  • Upsher-Smith Laboratories Inc.
Packagers
Dosage forms
FormRouteStrength
LiquidHemodialysis
SolutionHemodialysis
TabletOral
SolutionIntraocular
SolutionIrrigation
Kit; powder, for solution; tablet, delayed releaseOral
SolutionOphthalmic
SolutionIntra-arterial
Powder, for solutionNasogastric
Tablet, effervescentOral
PowderOral
SolutionIntrathecal
LiquidOphthalmic
SolutionUnknown
Tablet, extended releaseOral500 mg
LiquidOral100 mg/mL
LiquidIntraocular
Injection, solutionIntravenous
LiquidHemodialysis251.6 g
LiquidOral750 mg
Powder, for solutionOral1.5 g
Tablet, extended releaseOral1.5 g
Powder, for solutionOral1.86 g
TabletOral900 mg
LiquidOral20 meq/15mL
Tablet, film coated, extended releaseOral1500 mg/1
Tablet, film coated, extended releaseOral600 mg/1
Tablet, film coated, extended releaseOral750 mg/1
Tablet, extended releaseOral750 mg
SolutionOral10 %
SolutionOral3 g
SolutionOral200 mg
Powder, for solutionOral1.5 g/1
Powder, for solutionOral1.875 g/1
Powder, for solutionOral20 meq/1
Tablet, extended releaseOral1125 mg/1
Tablet, extended releaseOral1500 mg/1
Tablet, extended releaseOral10 meq/1
Capsule, extended releaseOral600 mg/1
Capsule, extended releaseOral750 mg/1
LiquidIrrigation
Capsule, extended releaseOral600 mg
Capsule, extended releaseOral750 mg
LiquidBuccal
SprayBuccal
Kit
Granule, effervescentOral
Injection, solution, concentrateIntravenous
SolutionOral
LiquidOral
Injection, solutionIntra-arterial
Powder, for solutionOral
CapsuleOral750 mg/1
Capsule, coated, extended releaseOral10 meq/1
Capsule, coated, extended releaseOral8 meq/1
InjectionIntravenous149 mg/mL
InjectionIntravenous2 meq/mL
Injection, solutionIntravenous10 meq/100mL
Injection, solutionIntravenous14.9 g/1000mL
Injection, solutionIntravenous200 meq/1000mL
Injection, solutionIntravenous22.4 g/1000mL
Injection, solutionIntravenous29.8 g/1000mL
Injection, solutionIntravenous30 meq/100mL
Injection, solutionIntravenous400 meq/1000mL
Injection, solutionIntravenous7.46 g/1000mL
Injection, solution, concentrateIntravenous149 mg/mL
Injection, solution, concentrateIntravenous2 meq/mL
Injection, solution, concentrateParenteral14.9 g/100mL
LiquidOral40 meq/15mL
LiquidOral40 meq/30mL
PowderOral1.5 g/1.74g
Powder, for solutionOral1.5 g/1.58g
Powder, for solutionOral1.5 g/1.74g
Powder, for solutionOral25 meq/1
SolutionOral1.5 g/15mL
SolutionOral20 meq/15mL
SolutionOral3 g/15mL
SolutionOral40 meq/15mL
SolutionOral40 meq/30mL
Tablet, extended releaseOral20 meq/1
Tablet, extended releaseOral600 mg/1
Tablet, extended releaseOral750 mg/1
Tablet, extended releaseOral8 meq/1
Tablet, film coated, extended releaseOral10 meq/1
Tablet, film coated, extended releaseOral8 meq/1
PowderHemodialysis12.5 g
PowderHemodialysis13 g
PowderHemodialysis15.26 g
PowderHemodialysis25 g
PowderHemodialysis7.65 g
TabletOral20 meq/1
Capsule, extended releaseOral10 meq/1
Capsule, extended releaseOral8 meq/1
SolutionIntravenous149 mg
SolutionIntravenous2 meq
SolutionIntravenous
SolutionIntravenous20 meq
LiquidIntravenous2 meq
SolutionIntravenous1.784 mg
SolutionIntravenous2.384 mg
LiquidIntravenous149 mg
LiquidIntravenous14.9 mg
LiquidIntravenous22.4 mg
LiquidIntravenous29.8 mg
LiquidIntravenous7.46 mg
PowderHemodialysis6.2 g
SolutionHemodialysis; Intravenous
LiquidIntravenous
InjectionIntravenous
IrrigantIrrigation
LiquidOral10 %
AerosolOral
Tablet, extended releaseOral600 mg
LiquidIntravenous150 mg
Powder, for solutionNasogastric; Oral
Prices
Unit descriptionCostUnit
Klor-Con 100 20meq Packets Box106.77USD box
Kay Ciel 30 20meq Packets Box58.99USD box
Rum-K-SF 15% Liquid 473ml Bottle45.98USD bottle
Klor-Con 30 25meq Packets Box36.99USD box
Colyte 240 gm Solution26.0USD bottle
Colyte-Flavored 240 gm Solution18.17USD bottle
K-Lor 20meq Packets1.92USD packet
K-lyte tablet eff1.43USD tablet
K-lyte-cl 25 meq tablet eff1.43USD tablet
Micro-K 10meq capsule1.41USD capsule
Micro-K 8meq capsule1.21USD capsule
Potassium cl 25 meq tablet eff0.94USD tablet
Micro-k 10 meq extencaps0.91USD each
Potassium Chloride CR 10meq capsule0.9USD capsule
Potassium Chloride CR 8meq capsule0.87USD capsule
K-Tabs 10meq Controlled Release Tabs0.68USD tab
K-tab er 10 meq tablet0.66USD tablet
Kaochlor-eff 20 meq tablet0.59USD tablet
K-tab 10 meq tablet sa0.58USD tablet
K-Lyte 25 meq Effervescent Tablet0.58USD tablet
Klor-con m20 tablet0.57USD tablet
Klor-Con/EF 25meq Effervescent Tabs0.57USD tab
Klor-Con 8meq Controlled Release Tabs0.56USD tab
Klor-Con M20 20meq Controlled Release Tabs0.55USD tab
Potassium Chloride Crys CR 20meq Controlled Release Tabs0.53USD tab
Potassium cl 20 meq tablet er0.52USD tablet
Potassium cl 20 meq tablet sa0.52USD tablet
Klor-con 10 meq tablet0.5USD tablet
Klor-con m15 tablet0.5USD tablet
Klotrix 10meq Controlled Release Tabs0.5USD tab
Potassium cl er 20 meq tablet0.49USD tablet
Klor-con-ef 25 meq tablet eff0.4USD tablet
Micro-k 8 meq extencaps0.34USD each
Kaon-Cl-10 10meq Controlled Release Tabs0.3USD tab
Klor-con m10 tablet0.3USD tablet
Potassium cl er 10 meq tablet0.3USD tablet
Potassium cl 10 meq tablet sa0.29USD tablet
Potassium Chloride Crys CR 10meq Controlled Release Tabs0.28USD tab
Potassium Chloride CR 10meq Controlled Release Tabs0.27USD tab
Potassium cl er 8 meq tablet0.26USD tablet
Kaon-cl 10 meq tablet sa0.23USD tablet
Potassium cl 2 meq/ml vial0.23USD ml
K-Dur 20 meq Sustained-Release Tablet0.21USD tablet
Potassium Chloride CR 8meq Controlled Release Tabs0.18USD tab
Klor-con 8 meq tablet0.16USD tablet
Slow K 8 meq Sustained-Release Tablet0.16USD tablet
Micro-K Extencaps 8 meq Sustained-Release Capsule0.1USD capsule
Apo-K 8 meq Sustained-Release Tablet0.09USD tablet
Potassium Chloride 40 Meq/15ml(20%) Liquid0.06USD ml
Potassium Chloride 20 Meq/15ml(10%) Liquid0.03USD ml
Potassium chloride crystals0.02USD g
K-10 Oral Liquid 1.33 meq/ml Liquid0.02USD ml
Colyte with flavor packets0.01USD ml
Pms - Potassium Chloride 1.33 meq/ml Liquid0.01USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US7084130 No2001-11-292021-11-29Us
US7169381 No2004-09-012024-09-01Us
US7291324 No2002-10-222022-10-22Us
US7658914 No2004-09-012024-09-01Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point770 °CNot Available
water solubilityFreely solubleNot Available
Predicted Properties
PropertyValueSource
logP0.2ChemAxon
pKa (Strongest Acidic)-7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9445
Blood Brain Barrier+0.975
Caco-2 permeable+0.6764
P-glycoprotein substrateNon-substrate0.9039
P-glycoprotein inhibitor INon-inhibitor0.9891
P-glycoprotein inhibitor IINon-inhibitor0.9866
Renal organic cation transporterNon-inhibitor0.9219
CYP450 2C9 substrateNon-substrate0.8116
CYP450 2D6 substrateNon-substrate0.717
CYP450 3A4 substrateNon-substrate0.7571
CYP450 1A2 substrateNon-inhibitor0.7551
CYP450 2C9 inhibitorNon-inhibitor0.8594
CYP450 2D6 inhibitorNon-inhibitor0.9314
CYP450 2C19 inhibitorNon-inhibitor0.8365
CYP450 3A4 inhibitorNon-inhibitor0.9576
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9002
Ames testNon AMES toxic0.6808
CarcinogenicityCarcinogens 0.7523
BiodegradationReady biodegradable0.6815
Rat acute toxicity1.9786 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9433
hERG inhibition (predictor II)Non-inhibitor0.9634
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
Taxonomy
DescriptionThis compound belongs to the class of chemical entities known as alkali metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is an alkali metal.
KingdomChemical entities
Super ClassInorganic compounds
ClassMixed metal/non-metal compounds
Sub ClassAlkali metal salts
Direct ParentAlkali metal chlorides
Alternative Parents
Substituents
  • Alkali metal chloride
  • Inorganic chloride salt
  • Inorganic salt
Molecular FrameworkNot Available
External Descriptors

Targets

Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Sodium:potassium:chloride symporter activity
Specific Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Gene Name:
SLC12A2
Uniprot ID:
P55011
Molecular Weight:
131445.825 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Hebert SC: Bartter syndrome. Curr Opin Nephrol Hypertens. 2003 Sep;12(5):527-32. [PubMed:12920401 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
binder
General Function:
Sodium:potassium:chloride symporter activity
Specific Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Gene Name:
SLC12A1
Uniprot ID:
Q13621
Molecular Weight:
121449.13 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol. 2005 Oct;16(10):2836-46. Epub 2005 Aug 10. [PubMed:16093448 ]
  4. Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006 May;26(3):224-33. [PubMed:16713495 ]
  5. Pressler CA, Heinzinger J, Jeck N, Waldegger P, Pechmann U, Reinalter S, Konrad M, Beetz R, Seyberth HW, Waldegger S: Late-onset manifestation of antenatal Bartter syndrome as a result of residual function of the mutated renal Na+-K+-2Cl- co-transporter. J Am Soc Nephrol. 2006 Aug;17(8):2136-42. Epub 2006 Jun 28. [PubMed:16807401 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
Gene Name:
SLC12A5
Uniprot ID:
Q9H2X9
Molecular Weight:
126182.49 Da
References
  1. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse cerebellum. Neurosci Res. 2007 Feb;57(2):322-5. Epub 2006 Nov 28. [PubMed:17134779 ]
  2. Tornberg J, Segerstrale M, Kulesskaya N, Voikar V, Taira T, Airaksinen MS: KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Neuropsychopharmacology. 2007 Apr;32(4):911-8. Epub 2006 Aug 16. [PubMed:16936706 ]
  3. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  4. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. Neuroscience. 2006 Dec;143(3):757-67. Epub 2006 Sep 27. [PubMed:17008020 ]
  5. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Rubidium ion transmembrane transporter activity
Specific Function:
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
Gene Name:
SLC12A6
Uniprot ID:
Q9UHW9
Molecular Weight:
127615.745 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acid...
Gene Name:
SLC12A7
Uniprot ID:
Q9Y666
Molecular Weight:
119104.84 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
Gene Name:
SLC12A4
Uniprot ID:
Q9UP95
Molecular Weight:
120648.73 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium:potassium:chloride symporter activity
Specific Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Gene Name:
SLC12A2
Uniprot ID:
P55011
Molecular Weight:
131445.825 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Hebert SC: Bartter syndrome. Curr Opin Nephrol Hypertens. 2003 Sep;12(5):527-32. [PubMed:12920401 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium:potassium:chloride symporter activity
Specific Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Gene Name:
SLC12A1
Uniprot ID:
Q13621
Molecular Weight:
121449.13 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol. 2005 Oct;16(10):2836-46. Epub 2005 Aug 10. [PubMed:16093448 ]
  4. Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006 May;26(3):224-33. [PubMed:16713495 ]
  5. Pressler CA, Heinzinger J, Jeck N, Waldegger P, Pechmann U, Reinalter S, Konrad M, Beetz R, Seyberth HW, Waldegger S: Late-onset manifestation of antenatal Bartter syndrome as a result of residual function of the mutated renal Na+-K+-2Cl- co-transporter. J Am Soc Nephrol. 2006 Aug;17(8):2136-42. Epub 2006 Jun 28. [PubMed:16807401 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
Gene Name:
SLC12A5
Uniprot ID:
Q9H2X9
Molecular Weight:
126182.49 Da
References
  1. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse cerebellum. Neurosci Res. 2007 Feb;57(2):322-5. Epub 2006 Nov 28. [PubMed:17134779 ]
  2. Tornberg J, Segerstrale M, Kulesskaya N, Voikar V, Taira T, Airaksinen MS: KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Neuropsychopharmacology. 2007 Apr;32(4):911-8. Epub 2006 Aug 16. [PubMed:16936706 ]
  3. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  4. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. Neuroscience. 2006 Dec;143(3):757-67. Epub 2006 Sep 27. [PubMed:17008020 ]
  5. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Rubidium ion transmembrane transporter activity
Specific Function:
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
Gene Name:
SLC12A6
Uniprot ID:
Q9UHW9
Molecular Weight:
127615.745 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acid...
Gene Name:
SLC12A7
Uniprot ID:
Q9Y666
Molecular Weight:
119104.84 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Protein kinase binding
Specific Function:
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.
Gene Name:
SLC12A4
Uniprot ID:
Q9UP95
Molecular Weight:
120648.73 Da
References
  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. [PubMed:16949074 ]
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. [PubMed:17418819 ]
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. [PubMed:16943364 ]
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Drug created on June 13, 2005 07:24 / Updated on February 26, 2017 03:11