Identification
NameMagnesium Hydroxide
Accession NumberDB09104
TypeSmall Molecule
GroupsApproved
Description

Magnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)2. It is naturally found as the mineral brucite. Magnesium hydroxide can be used an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke supressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as an antiperspirant underarm deodorant or for relief of canker sores (aphthous ulcers).

Structure
Thumb
Synonyms
Magnesium dihydroxide
Milk of magnesia
External IDs E-528 / INS NO.528 / INS-528
Product Ingredients Not Available
Approved Prescription ProductsNot Available
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-07-27Not applicableUs
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-08-05Not applicableUs
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-08-26Not applicableUs
Dermagran II Ointment - 0.25%Ointment.25 %TopicalTrans Canaderm Inc.1996-01-011996-09-10Canada
Dermagran II Ointment 0.25%Ointment.25 %TopicalCanadian Medical Supply Inc.1993-12-311996-09-09Canada
Dermagran II Ointment-ont Top 0.25%Ointment0.25 %TopicalCanderm G.P.1998-05-072008-08-06Canada
Dg Health Milk Of MagnesiaSuspension1200 mg/15mLOralDolgencorp2014-05-07Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2004-10-14Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2004-10-14Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2005-11-14Not applicableUs
Equate Milk Of MagnesiaLiquid1200 mg/15mLOralWalmart Stores2005-04-21Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen1990-02-15Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen2005-04-12Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen1990-04-15Not applicableUs
Good Sense Milk Of MagnesiaSuspension1200 mg/15mLOralL. Perrigo Company2005-07-11Not applicableUs
Good Sense Milk Of Magnesia Stimulant FreeSuspension1200 mg/15mLOralL. Perrigo Company1991-06-15Not applicableUs
Good Sense Milk Of Magnesia Stimulant FreeSuspension1200 mg/15mLOralL. Perrigo Company1991-06-15Not applicableUs
Harris Teeter Milk Of MagnesiaSuspension1200 mg/15mLOralHarris Teeter2015-03-30Not applicableUs
Healthy Accents Milk Of MagnesiaSuspension1200 mg/15mLOralDza Brands,2008-01-22Not applicableUs
Healthy Accents Milk Of MagnesiaSuspension1200 mg/15mLOralDza Brands,2008-01-22Not applicableUs
Humco Milk Of MagnesiaSuspension80 mg/mLOralHumco Holding Group. Inc.1998-03-25Not applicableUs
Leader Milk Of MagnesiaLiquid1200 mg/15mLOralCardinal Health2005-01-19Not applicableUs
Leader Milk Of MagnesiaSuspension1200 mg/15mLOralCardinal Health2014-01-23Not applicableUs
Leader Milk Of MagnesiaSuspension1200 mg/15mLOralCardinal Health1992-12-01Not applicableUs
Leader Milk Of Magnesia Saline LaxativeSuspension1200 mg/15mLOralCardinal Health1997-10-21Not applicableUs
MagmexLiquid1200 mg/15mLOralMenper Distributors2012-02-21Not applicableUs
Magnesia TabletsTablet385 mgOralVita Health Products Inc1990-12-312002-08-01Canada
Magnesium HydroxideLiquid400 mg/5mLOralRebel Distributors2010-03-22Not applicableUs
Medibest Milk Of MagnesiaLiquid1200 mg/15mLOralPurine Pharma Llc2016-10-12Not applicableUs
Milk Of MagnesiaSuspension2400 mg/10mLOralCardinal Health2011-06-07Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralPublix Supermarkets, Inc.2005-01-13Not applicableUs
Milk Of MagnesiaLiquid400 mgOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Milk Of MagnesiaSuspension2400 mg/30mLOralCardinal Health2011-06-07Not applicableUs
Milk Of MagnesiaConcentrate2400 mg/10mLOralWest Ward Pharmaceutical2001-03-12Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralKmart Corporation2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralKroger1999-10-20Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen2013-05-08Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralPhysicians Total Care, Inc.1997-06-19Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralWestern Family Foods2005-07-11Not applicableUs
Milk Of MagnesiaSuspension2400 mg/10mLOralPharmaceutical Associates, Inc.1982-04-20Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health2005-05-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee1997-02-05Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaConcentrate2400 mg/10mLOralRemedy Repack2015-09-04Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.1992-06-09Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralMedicine Shoppe International1991-02-15Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralHarris Teeter2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralKroger1999-10-20Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWestern Family Foods1992-11-04Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralMeijer Distribution1992-08-26Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health1992-08-10Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-24Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen2014-10-01Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee2005-07-18Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.2012-10-10Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralMedicine Shoppe International2003-02-24Not applicableUs
Milk Of MagnesiaSuspension2400 mg/30mLOralLLC Federal Solutions2013-08-12Not applicableUs
Milk Of MagnesiaLiquid400 mg/5mLOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWestern Family Foods1992-11-04Not applicableUs
Milk Of MagnesiaLiquid400 mg/5mLOralKinray2014-10-01Not applicableUs
Milk Of MagnesiaSuspension400 mg/5mLOralPharmaceutical Associates, Inc.1979-09-04Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralMeijer Distribution2004-10-18Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health1992-08-07Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen1995-11-10Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee1997-05-02Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.1994-10-14Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralSafeway1997-08-19Not applicableUs
Milk Of Magnesia 7% To 8.5%Suspension7.75 %OralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1971-12-311996-09-09Canada
Milk Of Magnesia CherryLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia LiquidLiquid8 gOralD.C. Labs Limited1951-12-312005-07-19Canada
Milk Of Magnesia MintLiquid1200 mg/15mLOralRugby2011-01-28Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralSelect Brand2009-06-032017-06-01Us
Milk Of Magnesia MintSuspension1200 mg/15mLOralAmerican Sales Company2009-03-122017-05-09Us
Milk Of Magnesia MintLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Milk Of Magnesia MintLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralChain Drug Consortium2009-06-03Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralWalgreens2010-02-042017-05-27Us
Milk Of Magnesia MintLiquid1200 mg/15mLOralMajor2011-06-06Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralNash Finch2009-03-202017-06-20Us
Milk Of Magnesia MintLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralBest Choice2009-07-082017-04-14Us
Milk Of Magnesia Mint Flav Tab 385mgTablet385 mgOralShoppers Drug Mart Inc.1978-12-311999-08-11Canada
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralChain Drug Consortium2009-06-03Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralBest Choice2009-04-022017-04-14Us
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralWalgreens2010-02-042017-05-26Us
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMajor2010-12-08Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralNash Finch2009-06-032017-06-20Us
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralTYA Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralCvs Health2009-05-282017-05-10Us
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralBest Choice2009-04-022017-04-14Us
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralAtlantic Biologicals Corps.2010-12-08Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralDollar General2009-03-232017-06-01Us
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralSelect Brand2009-11-032017-06-03Us
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralAmerican Sales Company2009-04-022017-05-06Us
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralPreferreed Pharmaceuticals Inc.2012-07-26Not applicableUs
Milk Of Magnesia Sus 440mg/5ml USPSuspension440 mgOralKsl Pharmaceuticals1995-12-311996-09-09Canada
Milk Of Magnesia Tablets 300mgTablet300 mgOralD.C. Labs Limited1951-12-312005-07-19Canada
Milk Of Magnesia U.S.P. - Sus 400mgSuspension400 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1996-07-162002-07-31Canada
Milk Of Magnesia U.S.P. - Sus 400mg/5mlSuspension400 mgOralKsl Pharmaceuticals1996-12-311998-08-13Canada
Milk Of Magnesia USPSuspension80 mgOralBdh Inc.1995-12-312000-08-03Canada
Milk Of Magnesia USP Sus 440mg/5mlSuspension440 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-311997-08-08Canada
Milk Of Magnesia Wild CherrySuspension1200 mg/15mLOralH.E.B.2010-03-022017-06-29Us
Milk Of Magnesia Wild CherrySuspension1200 mg/15mLOralChain Drug Consortium2010-01-08Not applicableUs
Milk Of Magnesia-sus 400mg/5mlSuspension400 mgOralDruggists' Corporation1995-12-311997-08-12Canada
Mint Milk Of MagnesiaSuspension1200 mg/15mLOralPublix Supermarkets, Inc.1994-09-02Not applicableUs
OriginalSuspension1200 mg/15mLOralPublix Supermarkets, Inc.1994-09-02Not applicableUs
Pedia-laxTablet, chewable400 mg/1OralC.B. Fleet Company, Inc.2008-03-01Not applicableUs
Phillip's Milk Of Magnesia Liq 80mg/ml PlainLiquid80 mgOralSterling Winthrop Inc.1992-12-311996-09-10Canada
Phillips ChewableTablet, chewable311 mg/1OralBayer2014-12-042017-06-20Us
Phillips Fresh Mint Milk Of MagnesiaLiquid1200 mg/15mLOralBayer Health Care Llc.2014-12-16Not applicableUs
Phillips Milk Of Magnesia Concentrated Fresh StrawberryLiquid2400 mg/15mLOralBayer Health Care Llc.2014-12-18Not applicableUs
Phillips Milk Of Magnesia Wild CherryLiquid1200 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-17Not applicableUs
Phillips Original Milk Of MagnesiaLiquid1200 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-16Not applicableUs
Shoprite Milk Of MagnesiaSuspension1200 mg/15mLOralWakfern Food Corporation2015-04-29Not applicableUs
Shoprite Milk Of MagnesiaSuspension1200 mg/15mLOralWakfern Food Corporation2015-04-29Not applicableUs
Sound Body Milk Of MagnesiaSuspension1200 mg/15mLOralBig Lots Stores, Inc.2016-03-24Not applicableUs
Stratuscare Milk Of MagnesiaSuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Stratuscare Milk Of Magnesia CherrySuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Stratuscare Milk Of Magnesia Sugar FreeSuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Sunmark Milk Of MagnesiaLiquid1200 mg/15mLOralMc Kesson2003-08-21Not applicableUs
Sunmark Milk Of MagnesiaLiquid1200 mg/15mLOralMc Kesson2003-08-21Not applicableUs
Sunmark Milk Of Magnesia MintLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Sunmark Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Sunmark Milk Of Magnesia Saline LaxativeLiquid1200 mg/15mLOralMc Kesson2005-02-11Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates2006-02-20Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates1991-09-10Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates1993-01-13Not applicableUs
Unapproved/Other Products Not Available
International BrandsNot Available
Brand mixtures
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Acid Controller CompleteTablet, chewableOralSafeway2008-08-06Not applicableUs
Acid Controller Complete Dual ActionTablet, chewableOralWalgreen2008-07-30Not applicableUs
Acid Reducer CompleteTablet, chewableOralRite Aid2009-05-15Not applicableUs
Acid Reducer Plus AntacidTablet, chewableOralRite Aid2010-06-03Not applicableUs
Acidex Tc Oral SuspensionSuspensionOralGen Drug Company Ltd.Not applicable1997-05-30Canada
Advanced Antacid CherryLiquidOralMc Kesson2012-06-01Not applicableUs
Advanced Antacid Regular StrengthLiquidOralSunmark (Mckesson)2012-06-01Not applicableUs
After Dinner AntacidTablet, chewableOralCvs Health2017-03-15Not applicableUs
AlmaconeTablet, chewableOralRugby2014-01-23Not applicableUs
Almacone Antacid AntigasSuspensionOralRugby2011-01-05Not applicableUs
Almacone Double StrengthSuspensionOralRugby2011-01-05Not applicableUs
Almagel Plus SusSuspensionOralLaboratoire Atlas Inc1997-04-09Not applicableCanada
Aluminum Hydroxide, Magnesium Hydroxide, SimethiconeSuspensionOralLLC Federal Solutions2013-08-12Not applicableUs
AlumoxTablet, chewableOralGuardian Drug Company2004-06-06Not applicableUs
Amphojel 500 SuspensionSuspensionOralAxcan Pharma1995-12-311997-08-07Canada
Amphojel Plus SuspensionSuspensionOralAxcan Pharma1995-12-311998-07-16Canada
AntacidLiquidOralWalgreen2002-11-20Not applicableUs
Antacid - Alumina and Magnesia Oral Suspension USPSuspensionOralD.C. Labs Limited1993-12-312005-07-19Canada
Antacid & AntigasSuspensionOralGericare PharmaceuticalsNot applicableNot applicableCanada
Antacid and AntigasLiquidOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Antacid Anti-gasSuspensionOralCvs Health2009-04-292017-05-10Us
Antacid AntigasSuspensionOralSelect Brand2009-11-032017-06-03Us
Antacid Antigas Maximum StrengthSuspensionOralSelect Brand2009-11-032017-06-03Us
Antacid Antigas Maximum Strength MintSuspensionOralCvs Health2009-06-032017-05-12Us
Antacid Cherry FlavoredLiquidOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Antacid Chewable TabTabletOralKsl Pharmaceuticals1991-12-311998-08-13Canada
Antacid Double StrengthLiquidOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Antacid Liquid Max Strength CherrySuspensionOralCvs Health2009-02-102017-08-02Us
Antacid Liquid MintSuspensionOralCvs Health2009-02-102017-05-26Us
Antacid Liquid SuspSuspensionOralShoppers Drug Mart Inc.1977-12-311997-08-15Canada
Antacid Magnesia and AluminaSuspensionOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1993-12-312002-07-31Canada
Antacid Maximum StrengthLiquidOralMeijer Distribution2005-10-19Not applicableUs
Antacid MintSuspensionOralSelect Brand2009-06-03Not applicableUs
Antacid Mint FlavoredLiquidOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Antacid Plus - SusSuspensionOralWes Pak Products Ltd.1998-03-202000-08-04Canada
Antacid Plus AntiflatuentSuspensionOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1993-12-312002-07-31Canada
Antacid Plus AntiflatulentSuspensionOralKsl Pharmaceuticals1991-12-311996-09-09Canada
Antacid Plus Antiflatulent - Alumina, Magnesia & Simethicone Oral SuspensionSuspensionOralD.C. Labs Limited1993-12-312005-07-19Canada
Antacid Plus Gas ReliefLiquidOralSafeway1996-04-25Not applicableUs
Antacid Plus Gas Relief Regular StrengthLiquidOralSafeway1993-10-22Not applicableUs
Antacid Regular StrengthLiquidOralH.E.B.1992-06-18Not applicableUs
Antacid Regular With Anti-gasLiquidOralJamp Pharma Corporation2006-02-16Not applicableCanada
Antacid SupremeSuspensionOralCvs Health2009-01-072016-10-13Us
Antacid Supreme CherrySuspensionOralAaron Industries, Inc.2009-03-242016-10-13Us
Antacid SusSuspensionOralKsl Pharmaceuticals1991-12-311996-09-09Canada
Antacid With Alumina, Magnesia Plus Simethicone Oral Suspension USPSuspensionOralJamp Pharma Corporation1995-08-21Not applicableCanada
Antacid With Anti-gas Liquid Extra Strength Mint FlavourLiquidOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Antiacide Avec Antiflatulent SusSuspensionOralTherapex Division De E Z Em Canada Inc1996-12-312004-06-10Canada
Antiacide SusSuspensionOralProduits Marc O (1987) Inc., Division Of Technilab Inc.1991-12-312000-08-24Canada
Babys Own Tummy TabTabletOralG.T. Fulford Pharmaceuticals1977-12-311998-06-25Canada
Berkley and Jensen Acid Controller CompleteTablet, chewableOralBJWC2009-07-08Not applicableUs
C2 Buffered TabTabletOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1986-12-311996-09-09Canada
C2 Buffered With Codeine TabTabletOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1986-12-311999-06-15Canada
Care One Acid Reducer and Antacid Dual ActionTablet, chewableOralAmerican Sales Company2008-08-01Not applicableUs
Care One Acid Reducer Plus Antacid Dual ActionTablet, chewableOralAmerican Sales Company2008-08-01Not applicableUs
Careone Acid Reducer CompleteTablet, chewableOralAmerican Sales Company2016-09-29Not applicableUs
Careone AntacidLiquidOralAmerican Sales Company2013-09-10Not applicableUs
Careone Antacid Regular StrengthLiquidOralAmerican Sales Company2012-11-18Not applicableUs
Careone Liquid AntacidLiquidOralAmerican Sales Company2012-09-27Not applicableUs
Centra Acid Plus-susSuspensionOralTherapex Division De E Z Em Canada Inc1995-12-312000-08-01Canada
Centra Acid-susSuspensionOralTherapex Division De E Z Em Canada Inc1995-12-312000-08-01Canada
CompleteTablet, chewableOralKroger2008-10-09Not applicableUs
Complete Dual ActionTablet, chewableOralHyvee2008-08-11Not applicableUs
Conrx ArTablet, chewableOralEagle Distributors,Inc.2013-03-18Not applicableUs
Dg Health AntacidSuspensionOralDolgencorp2014-05-09Not applicableUs
Dg Health Dual Action CompleteTablet, chewableOralDolgencorp2009-07-16Not applicableUs
Diovol EX TabTabletOralCarter Horner Corp.1984-12-312001-01-02Canada
Diovol Plus AFTablet, chewableOralChurch & Dwight Company, Inc.1995-12-31Not applicableCanada
Diovol Plus AF-suspensionSuspensionOralChurch & Dwight Company, Inc.1995-12-31Not applicableCanada
Diovol Plus SuspensionSuspensionOralChurch & Dwight Company, Inc.1963-12-31Not applicableCanada
Dual ActionTablet, chewableOralPublix Supermarkets, Inc.2008-12-05Not applicableUs
Dual Action CompleteTablet, chewableOralKroger2008-09-09Not applicableUs
Duo FusionTablet, chewableOralBoehringer Ingelheim2016-03-01Not applicableUs
EnoSolutionOralBelmora LLC2015-03-122017-06-30Us
Equaline AntacidLiquidOralSupervalu2004-10-22Not applicableUs
Equaline Antacid Regular StrengthSuspensionOralSupervalu2004-10-27Not applicableUs
Equaline Complete Dual ActionTablet, chewableOralSupervalu2008-09-02Not applicableUs
Equate Acid Reducer CompleteTablet, chewableOralWalmart Stores2008-08-08Not applicableUs
Equate Antacid Maximum StrengthLiquidOralWalmart Stores1993-07-20Not applicableUs
Equate Antacid Regular StrengthLiquidOralWalmart Stores1990-06-15Not applicableUs
Exchange Select Antacid Regular StrengthSuspensionOralArmy + Air Force Exchange Service2013-01-08Not applicableUs
Family Wellness Acid Controller CompleteTablet, chewableOralFamily Dollar Services2012-08-02Not applicableUs
Flanax AntacidLiquidOralBelmora LLC2012-12-062017-06-30Us
Flanax Antacid Anti-gasLiquidOralBelmora LLC2016-08-30Not applicableUs
Gaviscon Acid Relief Fmla Plus Gas Rel. TabTabletOralSterling Winthrop Inc.1993-12-311998-04-30Canada
Gaviscon Acid Relief Fmla Plus Gas Rel.liq.LiquidOralSterling Winthrop Inc.1993-12-311998-04-30Canada
Gaviscon Acid Relief Formula Extra StrengthLiquidOralSterling Winthrop Inc.1994-12-311998-04-30Canada
Gaviscon Acid Relief Formula LiquidLiquidOralSterling Winthrop Inc.1993-12-311998-04-30Canada
Gaviscon Acid Relief Formula TabletsTabletOralSterling Winthrop Inc.1993-12-311998-04-30Canada
Gelfos MGelOralBoryung Pharmaceutical Co., Ltd2016-02-282016-12-13Us
GelusilTablet, chewableOralWell Spring Pharmaceutical Corporation2008-09-24Not applicableUs
Gelusil Antacid & Anti-gasLiquidOralBoyd Pharmaceuticals Inc.2014-08-15Not applicableCanada
Gelusil Extra Strength LiqLiquidOralWarner Lambert Canada Inc.1992-12-311999-08-13Canada
Gelusil Extra Strength TabletsTabletOralWell Spring Pharmaceutical Corporation1992-12-312009-02-23Canada
Gelusil Liquid SusSuspensionOralPfizer Canada Inc., Consumer Healthcare Division1992-12-312005-02-17Canada
Gelusil Maximum StrengthSuspensionOralWell Spring Pharmaceutical Corporation2013-08-012016-02-28Us
Geri-lanta Antacid AntigasLiquidOralGericare Pharmaceuticals2000-01-01Not applicableUs
Geri-lanta Maximum StrengthLiquidOralGericare Pharmaceuticals2000-01-01Not applicableUs
Geri-lanta Supreme CherrySuspensionOralGericare Pharmaceuticals2000-01-01Not applicableUs
Geri-mox Antacid AntigasSuspensionOralGericare Pharmaceuticals2000-01-01Not applicableUs
Geri-mox Max CherrySuspensionOralGericare Pharmaceuticals2000-01-01Not applicableUs
Good Neighbor Pharmacy AntacidLiquidOralAmerisource Bergen1990-09-15Not applicableUs
Good Neighbor Pharmacy Antacid Regular StrengthTablet, chewableOralAmerisource Bergen2015-08-25Not applicableUs
Good Neighbor Pharmacy CompleteTablet, chewableOralAmerisource Bergen2008-08-04Not applicableUs
Good Neighbor Pharmacy Dual Action CompleteTablet, chewableOralAmerisource Bergen2016-01-29Not applicableUs
Good Sense AntacidLiquidOralL. Perrigo Company1990-04-15Not applicableUs
Good Sense Antacid Maximum StrengthSuspensionOralL. Perrigo Company2006-02-13Not applicableUs
Good Sense Antacid Regular StrengthSuspensionOralL. Perrigo Company1990-07-15Not applicableUs
Good Sense CompleteTablet, chewableOralL. Perrigo Company2008-08-05Not applicableUs
Good Sense Dual Action CompleteTablet, chewableOralL. Perrigo Company2016-01-06Not applicableUs
Harris Teeter AntacidLiquidOralHarris Teeter2015-03-21Not applicableUs
Harris Teeter Antacid Maximum StrengthSuspensionOralHarris Teeter2015-04-03Not applicableUs
Harris Teeter Antacid Regular StrengthSuspensionOralHarris Teeter2015-03-30Not applicableUs
Health Mart AntacidLiquidOralMc Kesson2012-03-20Not applicableUs
Health Mart CompleteTablet, chewableOralMc Kesson2013-01-05Not applicableUs
Health Mart Dual Action CompleteTablet, chewableOralMc Kesson2016-01-12Not applicableUs
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Maalox Advanced Antacid & AntigasSuspensionOralNovartis2002-04-222016-08-02Canada
Maalox Advanced Extra Strength Antacid & AntigasSuspensionOralNovartis2002-04-222016-08-02Canada
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Maalox Advanced Maximum Strength MintLiquidOralNovartis2008-03-06Not applicableUs
Maalox Advanced Maximum Strength Wild BerryLiquidOralNovartis2008-03-06Not applicableUs
Maalox Advanced Regular Strength MintLiquidOralNovartis2008-04-04Not applicableUs
Maalox AntacidLiquidOralPhysicians Total Care, Inc.2006-12-12Not applicableUs
Maalox Plus Extra Strength (cherry)TabletOralRhone Poulenc Rorer1992-12-311997-08-13Canada
Maalox Plus Extra Strength TabletsTabletOralNovartis1996-07-301999-07-21Canada
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Maalox Plus Tablets Lemon FlavourTabletOralRhone Poulenc Rorer1993-12-311997-08-13Canada
Maalox Plus Tablets Mint FlavourTabletOralRhone Poulenc Rorer1993-12-311997-08-13Canada
Maalox SuspensionSuspensionOralNovartis1996-12-312002-04-22Canada
Maalox TabletTabletOralRhone Poulenc Rorer1994-12-311997-08-13Canada
Maalox TabletsTabletOralNovartis1996-10-182000-07-19Canada
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Maalox Tc TabletTabletOralRhone Poulenc Rorer1994-12-311997-08-13Canada
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Mag-AL PlusSuspensionOralPharmaceutical Associates, Inc.2004-01-14Not applicableUs
Mag-AL Plus XsSuspensionOralPharmaceutical Associates, Inc.2004-01-14Not applicableUs
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MagsilTabletOralFortune Pharmacal Company LimitedNot applicableNot applicableCanada
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Maximum Strength Antacid Anti GasSuspensionOralPublix Supermarkets, Inc.2007-11-26Not applicableUs
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Medique Alamag PlusTablet, chewableOralUnifirst First Aid2008-12-302016-04-01Us
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Milk Of Magnesia Mineral Oil EmulsionEmulsionOralMeta Pharmaceuticals Inc.1991-12-311998-11-05Canada
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Mintox Maximum StrengthSuspensionOralMajor2011-02-01Not applicableUs
Mintox Plus TabsTablet, chewableOralMajor2007-03-14Not applicableUs
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Mylanta Liquid Extra Strength SusSuspensionOralPfizer Canada Inc., Consumer Healthcare Division1994-12-312005-02-17Canada
Mylanta Liquid Regular Strength SusSuspensionOralPfizer Canada Inc., Consumer Healthcare Division1994-12-312005-02-17Canada
Mylanta Maximum Strength Classic FlavorSuspensionOralInfirst Healthcare2016-03-21Not applicableUs
Mylanta Maximum Strength Vanilla Caramel FlavorSuspensionOralInfirst Healthcare2016-03-21Not applicableUs
Mylanta New Tonight Soothing Honey ChamomileSuspensionOralInfirst Healthcare2016-03-21Not applicableUs
Mylanta Plain Liq Double StrengthLiquidOralParke Davis Division, Warner Lambert Canada Inc.1977-12-311996-09-10Canada
Mylanta Plain Liq Double Strength SusSuspensionOralPfizer Canada Inc., Consumer Healthcare Division1978-12-312005-02-17Canada
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Pepcid CompleteTablet, chewableOralMcneil Consumer Healthcare Division Of Johnson & Johnson Inc2001-05-14Not applicableCanada
Phillips Dual ActionLiquidOralBayer Inc Consumer CareNot applicableNot applicableCanada
PMS-alumina Mag and Simethicone SusSuspensionOralPharmascience Inc1992-12-31Not applicableCanada
Preferred Plus CompleteTablet, chewableOralKinray2015-04-27Not applicableUs
Regular Strength AntacidSuspensionOralChain Drug Marketing Association2014-03-01Not applicableUs
Regular Strength Antacid Anti GasSuspensionOralPublix Supermarkets, Inc.1994-09-12Not applicableUs
Regular Strength Antacid MintLiquidOralCvs Health2015-06-01Not applicableUs
Rexall Antacid AdvancedSuspensionOralDolgencorp2014-06-10Not applicableUs
Ri MoxLiquidOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
RolaidsTabletOralAdams Canada, Division Of Warner Lambert Canada Inc.1987-12-312000-08-01Canada
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Rolaids Extra Strength MintTablet, chewableOralChattem, Inc.2013-09-01Not applicableUs
Rolaids Regular Strength MintTablet, chewableOralChattem, Inc.2013-09-01Not applicableUs
Rolaids Regular Strength- CherryLiquidOralChattem, Inc.2013-08-01Not applicableUs
Rolaids Regular Strength- MintLiquidOralChattem, Inc.2013-08-01Not applicableUs
Rolaids Ultra Strength Antacid OrangeTablet, chewableOralChattem, Inc.2014-12-01Not applicableUs
Rolaids Ultra Strength Antacid StrawberryTablet, chewableOralChattem, Inc.2014-12-01Not applicableUs
Rolaids Ultra Strength FruitTablet, chewableOralChattem, Inc.2013-09-01Not applicableUs
Rolaids Ultra Strength MintTablet, chewableOralChattem, Inc.2013-09-01Not applicableUs
Rolaids Ultra Strength- CherryLiquidOralChattem, Inc.2013-08-01Not applicableUs
Rolaids Ultra Strength- MintLiquidOralChattem, Inc.2013-08-01Not applicableUs
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Shoprite CompleteTablet, chewableOralWakfern Food Corporation2013-06-18Not applicableUs
Shoprite Dual Action CompleteTablet, chewableOralWakfern Food Corporation2016-02-05Not applicableUs
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Signature Care Acid Reducer CompleteTablet, chewableOralSafeway2016-03-02Not applicableUs
Signature Care Antacid Plus Gas ReliefSuspensionOralSafeway2015-07-22Not applicableUs
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Stratuscare Antacid and Antigas Regular StrengthSuspensionOralStratus Pharmaceuticals2014-04-26Not applicableUs
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Sunmark Antacid Maximum StrengthLiquidOralMc Kesson2006-05-01Not applicableUs
Sunmark Antacid Maximum Strength CherryLiquidOralMc Kesson2012-06-01Not applicableUs
Sunmark CompleteTablet, chewableOralMc Kesson2012-12-04Not applicableUs
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Topcare Antacid Regular StrengthLiquidOralTopco Associates1990-08-15Not applicableUs
Topcare CompleteTablet, chewableOralTopco Associates2008-08-05Not applicableUs
Topcare Complete Acid Reducer Plus AntacidTablet, chewableOralTopco Associates2008-08-05Not applicableUs
Topcare Dual Action CompleteTablet, chewableOralTopco Associates2016-02-29Not applicableUs
Univol SuspensionSuspensionOralCarter Horner Corp.1968-12-312003-03-14Canada
Up and Up Acid Controller Complete Dual ActionTablet, chewableOralTarget Corporation.2009-07-31Not applicableUs
Up and Up Antacid Anti Gas Regular StrengthSuspensionOralTarget Corporation.2009-06-16Not applicableUs
Up and Up Dual Action Acid Controller CompleteTablet, chewableOralTarget Corporation.2009-06-26Not applicableUs
Up and Up Famotidine CompleteTablet, chewableOralTarget Corporation.2015-04-27Not applicableUs
Categories
UNIINBZ3QY004S
CAS number1309-42-8
WeightAverage: 58.32
Monoisotopic: 57.990521206
Chemical FormulaH2MgO2
InChI KeyVTHJTEIRLNZDEV-UHFFFAOYSA-L
InChI
InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2
IUPAC Name
magnesium(2+) ion dihydroxide
SMILES
[OH-].[OH-].[Mg++]
Pharmacology
Indication

Magnesium hydroxide can be used as an antacid or a laxative depending on the administered dose.

As an antacid, it is used for the temporary relief of heartburn, upset stomach, sour stomach or acid indigestion.

As a laxative, it is used for the relief of occasional constipation by promoting bowel movements for 30 minutes and up to 6 hours.

Structured Indications
Pharmacodynamics

As an antacid, magnesium hydroxide suspension neutralizes gastric acid by reacting with hydrochloric acid in the stomach to form magnesium chloride and water. It is practically insoluble in water and does not have any effect until it reacts with the hydrochloric acid in the stomach. There, it decreases the direct acid irritant effect and increases the pH in the stomach leading to inactivation of pepsin. Magnesium hydroxide enhances the integrity of the mucosal barrier of the stomach as well as improving the tone of both the gastric and esophageal sphincters.

As a laxative, the magnesium hydroxide works by increasing the osmotic effect in the intestinal tract and drawing water in. This creates distension of the colon which results in an increase in peristaltic movement and bowel evacuation.

Mechanism of action

The suspension of magnesium hydroxide is ingested and enters the stomach. According to the amount ingested, the magnesium hydroxide will either act as an antacid or a laxative.

Through the ingestion of 0.5-1.5 grams (in adults) the magnesium hydroxide will act by simple acid neutralization in the stomach. The hydroxide ions from the magnesium hydroxide suspension will combine with the acidic H+ ions of the hydrochloric acid made by the stomachs parietal cells. This neutralization reaction will result in the formation of magnesium chloride and water.

Through the ingestion of 2-5 grams (in adults) the magnesium hydroxide acts as a laxative in the colon. The majority of the suspension is not absorbed in the intestinal tract and will create an osmotic effect to draw water into the gut from surrounding tissues. With this increase of water in the intestines, the feces will soften and the intraluminal volume of the feces will increase. These effects still stimulate intestinal motility and induce the urge to defecate. Magnesium hydroxide will also release cholecystokinin (CKK) in the intestines which will accumulate water and electrolytes in the lumen and furthermore increase intestinal motility.

Related Articles
Absorption

About 15%-50% of magnesium hydroxide is absorbed very slowly through the small intestine.

Volume of distribution

The peak action and distribution of magnesium hydroxide are variable.

Protein binding

Magnesium hydroxide does not have any protein binding properties.

Metabolism

Unless a patient is deficient in magnesium, very little is absorbed by the intestine. Overall, about 15%-50% of the magnesium hydroxide suspension is absorbed systemically. However, it does not undergo any metabolism as it is rapidly excreted in the urine.

Route of elimination

After oral administration, up to 50% of the magnesium hydroxide suspension may be absorbed as magnesium ions through the small intestines and then rapidly excreted in the urine through the kidneys. The unabsorbed drug is mainly excreted in the feces and saliva.

Half life

N/A

Clearance

Magnesium hydroxide is mainly excreted in the urine by the kidneys. Since the kidneys play a major role in its clearance, individuals with renal failure are at risk of hypermagnesemia with long term consumption as the appropriate amounts of magnesium may not be excreted.

Toxicity

LD50=8500 mg/kg (rat, oral)

Common side effects include drowsiness or flushing (warmth, redness or tingly feeling).

Daily use of magnesium hydroxide can result in fluid and electrolyte disturbances.

Excessive use of the laxative effects of magnesium hydroxide may result in abdominal cramping, nausea and/or diarrhea.

In overdose, symptoms of gastrointestinal irritation and/or watery diarrhea may occur.

Magnesium hydroxide poisoning can result in hypermagnesemia which includes symptoms of: nausea, vomiting, flushing, thirst, hypotension, drowsiness, confusion, loss of tendon reflexes, muscle weakness, respiratory depression, cardiac arrhythmias, coma and cardiac arrest.

Not to be used in individuals with any form of kidney disease or renal failure, a magnesium restricted diet or with any sudden changes in bowel movement lasting over two weeks. Also not to be used in those individuals with abdominal pain, nausea, vomiting, symptoms of appendicitis or myocardial damage, heart block, fecal impaction, rectal fissures, intestinal obstruction or perforation or renal disease. Not to be used in women who are about to deliver as magnesium crosses the placenta and is excreted in small amounts in breast milk.

Using magnesium hydroxide with aluminum hydroxide can decrease the absorption rate of these drugs.

Magnesium hydroxide can react with digoxin, dicoumerol and cimetidine.

Use of ibuprofen with magnesium hydroxide can increase the absorption of the ibuprofen.

Use of magnesium hydroxide with penicallamine, bisphosphates, ketoconazole, quinolones or tetracycline can decrease the absorption of these drugs.

Enteric-coated tablets can be prematurely released when taken with magnesium hydroxide.

It is important to routinely monitor levels of serum magnesium and potassium in patients using magnesium hydroxide. Serum magnesium levels are necessary to determine how much magnesium is being absorbed and how much is being excreted by the kidneys. Excessive diarrhea can occur from use of magnesium hydroxide and thus it is important to also monitor serum potassium levels to ensure hypokalemia does not occur.

Affected organisms
  • Humans and other mammals
PathwaysNot Available
Pharmacogenomic Effects/ADRs Not Available
Interactions
Drug Interactions
DrugInteractionDrug group
16-BromoepiandrosteroneThe bioavailability of 16-Bromoepiandrosterone can be decreased when combined with Magnesium hydroxide.Investigational
19-norandrostenedioneThe bioavailability of 19-norandrostenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
2,5-Dimethoxy-4-ethylamphetamineMagnesium hydroxide may decrease the excretion rate of 2,5-Dimethoxy-4-ethylamphetamine which could result in a higher serum level.Experimental, Illicit
3,4-MethylenedioxyamphetamineMagnesium hydroxide may decrease the excretion rate of 3,4-Methylenedioxyamphetamine which could result in a higher serum level.Experimental, Illicit
3,4-MethylenedioxymethamphetamineMagnesium hydroxide may decrease the excretion rate of 3,4-Methylenedioxymethamphetamine which could result in a higher serum level.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamineMagnesium hydroxide may decrease the excretion rate of 4-Bromo-2,5-dimethoxyamphetamine which could result in a higher serum level.Experimental, Illicit
5-androstenedioneThe bioavailability of 5-androstenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
AcepromazineMagnesium hydroxide can cause a decrease in the absorption of Acepromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
AceprometazineMagnesium hydroxide can cause a decrease in the absorption of Aceprometazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
AlclometasoneThe bioavailability of Alclometasone can be decreased when combined with Magnesium hydroxide.Approved
AldosteroneThe bioavailability of Aldosterone can be decreased when combined with Magnesium hydroxide.Experimental
Alendronic acidThe serum concentration of Alendronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
AlfacalcidolThe serum concentration of Magnesium hydroxide can be increased when it is combined with Alfacalcidol.Approved, Nutraceutical
AlimemazineMagnesium hydroxide can cause a decrease in the absorption of Alimemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
AllopurinolMagnesium hydroxide can cause a decrease in the absorption of Allopurinol resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
AmcinonideThe bioavailability of Amcinonide can be decreased when combined with Magnesium hydroxide.Approved
AmlodipineThe risk or severity of adverse effects can be increased when Amlodipine is combined with Magnesium hydroxide.Approved
AmphetamineMagnesium hydroxide may decrease the excretion rate of Amphetamine which could result in a higher serum level.Approved, Illicit
AmrinoneThe risk or severity of adverse effects can be increased when Amrinone is combined with Magnesium hydroxide.Approved
AndrostenedioneThe bioavailability of 4-Androstenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
AnecortaveThe bioavailability of Anecortave can be decreased when combined with Magnesium hydroxide.Investigational
AtazanavirMagnesium hydroxide can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
AtorvastatinThe serum concentration of Atorvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
Atracurium besylateMagnesium hydroxide may increase the neuromuscular blocking activities of Atracurium besylate.Approved
AzelnidipineThe risk or severity of adverse effects can be increased when Azelnidipine is combined with Magnesium hydroxide.Approved
AzimilideThe risk or severity of adverse effects can be increased when Azimilide is combined with Magnesium hydroxide.Investigational
BarnidipineThe risk or severity of adverse effects can be increased when Barnidipine is combined with Magnesium hydroxide.Approved
Beclomethasone dipropionateThe bioavailability of Beclomethasone dipropionate can be decreased when combined with Magnesium hydroxide.Approved, Investigational
BenidipineThe risk or severity of adverse effects can be increased when Benidipine is combined with Magnesium hydroxide.Approved
BenzphetamineMagnesium hydroxide may decrease the excretion rate of Benzphetamine which could result in a higher serum level.Approved, Illicit
BepridilThe risk or severity of adverse effects can be increased when Bepridil is combined with Magnesium hydroxide.Approved, Withdrawn
BetamethasoneThe bioavailability of Betamethasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
BisacodylThe therapeutic efficacy of Bisacodyl can be decreased when used in combination with Magnesium hydroxide.Approved
Bismuth SubcitrateThe therapeutic efficacy of Bismuth Subcitrate can be decreased when used in combination with Magnesium hydroxide.Approved
BL-1020Magnesium hydroxide can cause a decrease in the absorption of BL-1020 resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
BosutinibThe serum concentration of Bosutinib can be decreased when it is combined with Magnesium hydroxide.Approved
BudesonideThe bioavailability of Budesonide can be decreased when combined with Magnesium hydroxide.Approved
CalcitriolThe serum concentration of Magnesium hydroxide can be increased when it is combined with Calcitriol.Approved, Nutraceutical
CaptoprilThe serum concentration of Captopril can be decreased when it is combined with Magnesium hydroxide.Approved
CarboxyamidotriazoleThe risk or severity of adverse effects can be increased when Cai is combined with Magnesium hydroxide.Investigational
CefditorenThe serum concentration of Cefditoren can be decreased when it is combined with Magnesium hydroxide.Approved
CefpodoximeThe serum concentration of Cefpodoxime can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
CefuroximeThe serum concentration of Cefuroxime can be decreased when it is combined with Magnesium hydroxide.Approved
CerivastatinThe serum concentration of Cerivastatin can be decreased when it is combined with Magnesium hydroxide.Withdrawn
ChloroquineThe serum concentration of Chloroquine can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
ChlorphentermineMagnesium hydroxide may decrease the excretion rate of Chlorphentermine which could result in a higher serum level.Illicit, Withdrawn
ChlorpromazineMagnesium hydroxide can cause a decrease in the absorption of Chlorpromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
ChlortetracyclineMagnesium hydroxide can cause a decrease in the absorption of Chlortetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
CiclesonideThe bioavailability of Ciclesonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
CilnidipineThe risk or severity of adverse effects can be increased when Cilnidipine is combined with Magnesium hydroxide.Approved
CinnarizineThe risk or severity of adverse effects can be increased when Cinnarizine is combined with Magnesium hydroxide.Approved
CinoxacinMagnesium hydroxide can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
CiprofloxacinMagnesium hydroxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
Cisatracurium besylateMagnesium hydroxide may increase the neuromuscular blocking activities of Cisatracurium besylate.Approved
ClevidipineThe risk or severity of adverse effects can be increased when Clevidipine is combined with Magnesium hydroxide.Approved
ClobetasolThe bioavailability of Clobetasol can be decreased when combined with Magnesium hydroxide.Investigational
Clobetasol propionateThe bioavailability of Clobetasol propionate can be decreased when combined with Magnesium hydroxide.Approved
ClocortoloneThe bioavailability of Clocortolone can be decreased when combined with Magnesium hydroxide.Approved
Clodronic AcidThe serum concentration of Clodronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
Cortisone acetateThe bioavailability of Cortisone acetate can be decreased when combined with Magnesium hydroxide.Approved
CysteamineThe therapeutic efficacy of Cysteamine can be decreased when used in combination with Magnesium hydroxide.Approved, Investigational
Dabigatran etexilateThe serum concentration of Dabigatran etexilate can be decreased when it is combined with Magnesium hydroxide.Approved
DabrafenibThe serum concentration of Dabrafenib can be decreased when it is combined with Magnesium hydroxide.Approved
DarodipineThe risk or severity of adverse effects can be increased when Darodipine is combined with Magnesium hydroxide.Experimental
DasatinibMagnesium hydroxide can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
DecamethoniumMagnesium hydroxide may increase the neuromuscular blocking activities of Decamethonium.Approved
DeferiproneThe serum concentration of Deferiprone can be decreased when it is combined with Magnesium hydroxide.Approved
DelavirdineThe serum concentration of Delavirdine can be decreased when it is combined with Magnesium hydroxide.Approved
DemeclocyclineMagnesium hydroxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
DesoximetasoneThe bioavailability of Desoximetasone can be decreased when combined with Magnesium hydroxide.Approved
Desoxycorticosterone PivalateThe bioavailability of Desoxycorticosterone Pivalate can be decreased when combined with Magnesium hydroxide.Experimental, Vet Approved
DexamethasoneThe bioavailability of Dexamethasone can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
DexmethylphenidateMagnesium hydroxide can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.Approved
DextroamphetamineMagnesium hydroxide may decrease the excretion rate of Dextroamphetamine which could result in a higher serum level.Approved, Illicit
DiethylpropionMagnesium hydroxide may decrease the excretion rate of Diethylpropion which could result in a higher serum level.Approved, Illicit
DiflorasoneThe bioavailability of Diflorasone can be decreased when combined with Magnesium hydroxide.Approved
DifluocortoloneThe bioavailability of Difluocortolone can be decreased when combined with Magnesium hydroxide.Approved
DifluprednateThe bioavailability of Difluprednate can be decreased when combined with Magnesium hydroxide.Approved
DiltiazemThe risk or severity of adverse effects can be increased when Diltiazem is combined with Magnesium hydroxide.Approved
Dipotassium phosphateThe serum concentration of Dipotassium phosphate can be decreased when it is combined with Magnesium hydroxide.Approved
DolutegravirThe serum concentration of Dolutegravir can be decreased when it is combined with Magnesium hydroxide.Approved
Domoic AcidMagnesium hydroxide may increase the neuromuscular blocking activities of Domoic Acid.Experimental
Doxacurium chlorideMagnesium hydroxide may increase the neuromuscular blocking activities of Doxacurium chloride.Approved
DoxycyclineMagnesium hydroxide can cause a decrease in the absorption of Doxycycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational, Vet Approved
EfonidipineThe risk or severity of adverse effects can be increased when Efonidipine is combined with Magnesium hydroxide.Approved
EltrombopagThe serum concentration of Eltrombopag can be decreased when it is combined with Magnesium hydroxide.Approved
ElvitegravirThe serum concentration of Elvitegravir can be decreased when it is combined with Magnesium hydroxide.Approved
EnoxacinMagnesium hydroxide can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
EperisoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium hydroxide.Approved, Investigational
EquileninThe bioavailability of Equilenin can be decreased when combined with Magnesium hydroxide.Experimental
EquilinThe bioavailability of Equilin can be decreased when combined with Magnesium hydroxide.Approved
ErlotinibThe serum concentration of Erlotinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
EstroneThe bioavailability of Estrone can be decreased when combined with Magnesium hydroxide.Approved
Estrone sulfateThe bioavailability of Estrone sulfate can be decreased when combined with Magnesium hydroxide.Approved
Etidronic acidThe serum concentration of Etidronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
FelodipineThe risk or severity of adverse effects can be increased when Felodipine is combined with Magnesium hydroxide.Approved, Investigational
FendilineThe risk or severity of adverse effects can be increased when Fendiline is combined with Magnesium hydroxide.Withdrawn
Ferric CarboxymaltoseMagnesium hydroxide can cause a decrease in the absorption of Ferric Carboxymaltose resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Ferric CitrateMagnesium hydroxide can cause a decrease in the absorption of Ferric Citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Ferric pyrophosphateMagnesium hydroxide can cause a decrease in the absorption of Ferric pyrophosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
FexofenadineThe serum concentration of Fexofenadine can be decreased when it is combined with Magnesium hydroxide.Approved
FleroxacinMagnesium hydroxide can cause a decrease in the absorption of Fleroxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
FludrocortisoneThe bioavailability of Fludrocortisone can be decreased when combined with Magnesium hydroxide.Approved
FlumequineMagnesium hydroxide can cause a decrease in the absorption of Flumequine resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
FlumethasoneThe bioavailability of Flumethasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Magnesium hydroxide.Approved
FlunisolideThe bioavailability of Flunisolide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
Fluocinolone AcetonideThe bioavailability of Fluocinolone Acetonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
FluocinonideThe bioavailability of Fluocinonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
FluocortoloneThe bioavailability of Fluocortolone can be decreased when combined with Magnesium hydroxide.Approved, Withdrawn
FluorometholoneThe bioavailability of Fluorometholone can be decreased when combined with Magnesium hydroxide.Approved
FluphenazineMagnesium hydroxide can cause a decrease in the absorption of Fluphenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
FluprednideneThe bioavailability of Fluprednidene can be decreased when combined with Magnesium hydroxide.Approved, Withdrawn
FlurandrenolideThe bioavailability of Flurandrenolide can be decreased when combined with Magnesium hydroxide.Approved
Fluticasone furoateThe bioavailability of Fluticasone furoate can be decreased when combined with Magnesium hydroxide.Approved
Fluticasone propionateThe bioavailability of Fluticasone Propionate can be decreased when combined with Magnesium hydroxide.Approved
FluvastatinThe serum concentration of Fluvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
FormestaneThe bioavailability of Formestane can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Withdrawn
FosinoprilThe serum concentration of Fosinopril can be decreased when it is combined with Magnesium hydroxide.Approved
GabapentinMagnesium hydroxide may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.Approved, Investigational
Gallamine TriethiodideMagnesium hydroxide may increase the neuromuscular blocking activities of Gallamine Triethiodide.Approved
GallopamilThe risk or severity of adverse effects can be increased when Gallopamil is combined with Magnesium hydroxide.Investigational
GatifloxacinMagnesium hydroxide can cause a decrease in the absorption of Gatifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
GefitinibThe serum concentration of Gefitinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
GemifloxacinMagnesium hydroxide can cause a decrease in the absorption of Gemifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
GrepafloxacinMagnesium hydroxide can cause a decrease in the absorption of Grepafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
HE3286The bioavailability of HE3286 can be decreased when combined with Magnesium hydroxide.Investigational
HydrocortisoneThe bioavailability of Hydrocortisone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
HydroxyamphetamineMagnesium hydroxide may decrease the excretion rate of Hydroxyamphetamine hydrobromide which could result in a higher serum level.Approved
HyoscyamineThe serum concentration of Hyoscyamine can be decreased when it is combined with Magnesium hydroxide.Approved
IbandronateThe serum concentration of Ibandronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
IronMagnesium hydroxide can cause a decrease in the absorption of Iron resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Iron DextranMagnesium hydroxide can cause a decrease in the absorption of Iron Dextran resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
Iron saccharateMagnesium hydroxide can cause a decrease in the absorption of Iron saccharate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
IsoniazidMagnesium hydroxide can cause a decrease in the absorption of Isoniazid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
IsradipineThe risk or severity of adverse effects can be increased when Isradipine is combined with Magnesium hydroxide.Approved
ItraconazoleThe serum concentration of Itraconazole can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
KetoconazoleThe serum concentration of Ketoconazole can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
LacidipineThe risk or severity of adverse effects can be increased when Lacidipine is combined with Magnesium hydroxide.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Magnesium hydroxide.Approved, Investigational
LedipasvirThe serum concentration of Ledipasvir can be decreased when it is combined with Magnesium hydroxide.Approved
LercanidipineThe risk or severity of adverse effects can be increased when Lercanidipine is combined with Magnesium hydroxide.Approved, Investigational
LevofloxacinMagnesium hydroxide can cause a decrease in the absorption of Levofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
LevothyroxineThe serum concentration of Levothyroxine can be decreased when it is combined with Magnesium hydroxide.Approved
Lipoic AcidMagnesium hydroxide can cause a decrease in the absorption of Lipoic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Nutraceutical
LisdexamfetamineMagnesium hydroxide may decrease the excretion rate of Lisdexamfetamine which could result in a higher serum level.Approved, Investigational
LomefloxacinMagnesium hydroxide can cause a decrease in the absorption of Lomefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
LovastatinThe serum concentration of Lovastatin can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
Magnesium SulfateThe risk or severity of adverse effects can be increased when Magnesium Sulfate is combined with Magnesium hydroxide.Approved, Vet Approved
ManidipineThe risk or severity of adverse effects can be increased when Manidipine is combined with Magnesium hydroxide.Approved
ME-609The bioavailability of ME-609 can be decreased when combined with Magnesium hydroxide.Investigational
MecamylamineThe serum concentration of Mecamylamine can be increased when it is combined with Magnesium hydroxide.Approved
MedrysoneThe bioavailability of Medrysone can be decreased when combined with Magnesium hydroxide.Approved
MemantineThe serum concentration of Memantine can be increased when it is combined with Magnesium hydroxide.Approved, Investigational
MephedroneMagnesium hydroxide may decrease the excretion rate of Mephedrone which could result in a higher serum level.Investigational
MephentermineMagnesium hydroxide may decrease the excretion rate of Mephentermine which could result in a higher serum level.Approved
MesalazineThe therapeutic efficacy of Mesalazine can be decreased when used in combination with Magnesium hydroxide.Approved
MesoridazineMagnesium hydroxide can cause a decrease in the absorption of Mesoridazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
MethamphetamineMagnesium hydroxide may decrease the excretion rate of Methamphetamine which could result in a higher serum level.Approved, Illicit
MethenamineThe therapeutic efficacy of Hexamethylenetetramine can be decreased when used in combination with Magnesium hydroxide.Approved, Vet Approved
MethotrimeprazineMagnesium hydroxide can cause a decrease in the absorption of Methotrimeprazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Methylene blueMagnesium hydroxide can cause a decrease in the absorption of Methylene blue resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
MethylphenidateMagnesium hydroxide can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.Approved, Investigational
MethylprednisoloneThe bioavailability of Methylprednisolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
MetocurineMagnesium hydroxide may increase the neuromuscular blocking activities of Metocurine.Approved
Metocurine IodideMagnesium hydroxide may increase the neuromuscular blocking activities of Metocurine Iodide.Withdrawn
MevastatinThe serum concentration of Mevastatin can be decreased when it is combined with Magnesium hydroxide.Experimental
MibefradilThe risk or severity of adverse effects can be increased when Mibefradil is combined with Magnesium hydroxide.Withdrawn
MinocyclineMagnesium hydroxide can cause a decrease in the absorption of Minocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
MisoprostolThe risk or severity of adverse effects can be increased when Magnesium hydroxide is combined with Misoprostol.Approved
MivacuriumMagnesium hydroxide may increase the neuromuscular blocking activities of Mivacurium.Approved
MMDAMagnesium hydroxide may decrease the excretion rate of MMDA which could result in a higher serum level.Experimental, Illicit
MometasoneThe bioavailability of Mometasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
MoricizineMagnesium hydroxide can cause a decrease in the absorption of Moricizine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
MoxifloxacinMagnesium hydroxide can cause a decrease in the absorption of Moxifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
Mycophenolic acidThe serum concentration of Mycophenolic acid can be decreased when it is combined with Magnesium hydroxide.Approved
NaftopidilThe risk or severity of adverse effects can be increased when Naftopidil is combined with Magnesium hydroxide.Investigational
Nalidixic AcidMagnesium hydroxide can cause a decrease in the absorption of Nalidixic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
NCX 1022The bioavailability of NCX 1022 can be decreased when combined with Magnesium hydroxide.Investigational
NeosaxitoxinMagnesium hydroxide may increase the neuromuscular blocking activities of Neosaxitoxin.Investigational
NicardipineThe risk or severity of adverse effects can be increased when Nicardipine is combined with Magnesium hydroxide.Approved
NifedipineThe risk or severity of adverse effects can be increased when Nifedipine is combined with Magnesium hydroxide.Approved
NiguldipineThe risk or severity of adverse effects can be increased when Niguldipine is combined with Magnesium hydroxide.Experimental
NilotinibThe serum concentration of Nilotinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
NiludipineThe risk or severity of adverse effects can be increased when Niludipine is combined with Magnesium hydroxide.Experimental
NilvadipineThe risk or severity of adverse effects can be increased when Nilvadipine is combined with Magnesium hydroxide.Approved
NimesulideThe risk or severity of adverse effects can be increased when Nimesulide is combined with Magnesium hydroxide.Approved, Withdrawn
NimodipineThe risk or severity of adverse effects can be increased when Nimodipine is combined with Magnesium hydroxide.Approved
NisoldipineThe risk or severity of adverse effects can be increased when Nisoldipine is combined with Magnesium hydroxide.Approved
NitrendipineThe risk or severity of adverse effects can be increased when Nitrendipine is combined with Magnesium hydroxide.Approved
NorfloxacinMagnesium hydroxide can cause a decrease in the absorption of Norfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
OfloxacinMagnesium hydroxide can cause a decrease in the absorption of Ofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Oleoyl-estroneThe bioavailability of Oleoyl estrone can be decreased when combined with Magnesium hydroxide.Investigational
OxytetracyclineMagnesium hydroxide can cause a decrease in the absorption of Oxytetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PamidronateThe serum concentration of Pamidronate can be decreased when it is combined with Magnesium hydroxide.Approved
PancuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Pancuronium.Approved
ParamethasoneThe bioavailability of Paramethasone can be decreased when combined with Magnesium hydroxide.Approved
PazopanibThe serum concentration of Pazopanib can be decreased when it is combined with Magnesium hydroxide.Approved
PazufloxacinMagnesium hydroxide can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PefloxacinMagnesium hydroxide can cause a decrease in the absorption of Pefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PenicillamineThe serum concentration of Penicillamine can be decreased when it is combined with Magnesium hydroxide.Approved
PerazineMagnesium hydroxide can cause a decrease in the absorption of Perazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PerhexilineThe risk or severity of adverse effects can be increased when Perhexiline is combined with Magnesium hydroxide.Approved
PerphenazineMagnesium hydroxide can cause a decrease in the absorption of Perphenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PhentermineMagnesium hydroxide may decrease the excretion rate of Phentermine which could result in a higher serum level.Approved, Illicit
PinaveriumThe risk or severity of adverse effects can be increased when Pinaverium is combined with Magnesium hydroxide.Approved
PipecuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Pipecuronium.Approved
PitavastatinThe serum concentration of Pitavastatin can be decreased when it is combined with Magnesium hydroxide.Approved
PrasteroneThe bioavailability of Prasterone can be decreased when combined with Magnesium hydroxide.Approved, Nutraceutical
Prasterone sulfateThe bioavailability of dehydroepiandrosterone sulfate can be decreased when combined with Magnesium hydroxide.Investigational
PravastatinThe serum concentration of Pravastatin can be decreased when it is combined with Magnesium hydroxide.Approved
PrednicarbateThe bioavailability of Prednicarbate can be decreased when combined with Magnesium hydroxide.Approved
PrednisoloneThe bioavailability of Prednisolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
PrednisoneThe bioavailability of Prednisone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Magnesium hydroxide.Approved, Illicit, Investigational
PregnenoloneThe bioavailability of Pregnenolone can be decreased when combined with Magnesium hydroxide.Experimental
PrenylamineThe risk or severity of adverse effects can be increased when Prenylamine is combined with Magnesium hydroxide.Withdrawn
ProchlorperazineMagnesium hydroxide can cause a decrease in the absorption of Prochlorperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PromazineMagnesium hydroxide can cause a decrease in the absorption of Promazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PromethazineMagnesium hydroxide can cause a decrease in the absorption of Promethazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PrulifloxacinMagnesium hydroxide can cause a decrease in the absorption of Prulifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PseudoephedrineMagnesium hydroxide may decrease the excretion rate of Pseudoephedrine which could result in a higher serum level.Approved
QuinidineMagnesium hydroxide may decrease the excretion rate of Quinidine which could result in a higher serum level.Approved
QuinineThe serum concentration of Quinine can be decreased when it is combined with Magnesium hydroxide.Approved
RaltegravirThe serum concentration of Raltegravir can be decreased when it is combined with Magnesium hydroxide.Approved
RapacuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Rapacuronium.Withdrawn
RilpivirineThe serum concentration of Rilpivirine can be decreased when it is combined with Magnesium hydroxide.Approved
RimexoloneThe bioavailability of Rimexolone can be decreased when combined with Magnesium hydroxide.Approved
RiociguatThe serum concentration of Riociguat can be decreased when it is combined with Magnesium hydroxide.Approved
RisedronateThe serum concentration of Risedronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
RitobegronMagnesium hydroxide may decrease the excretion rate of Ritobegron which could result in a higher serum level.Investigational
RocuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Rocuronium.Approved
RosoxacinMagnesium hydroxide can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
RosuvastatinThe serum concentration of Rosuvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
SimvastatinThe serum concentration of Simvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
Sodium glycerophosphateThe serum concentration of Sodium glycerophosphate can be decreased when it is combined with Magnesium hydroxide.Approved
Sodium phosphateThe serum concentration of Sodium phosphate can be decreased when it is combined with Magnesium hydroxide.Approved
SotalolThe serum concentration of Sotalol can be decreased when it is combined with Magnesium hydroxide.Approved
SparfloxacinMagnesium hydroxide can cause a decrease in the absorption of Sparfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Strontium ranelateThe serum concentration of Strontium ranelate can be decreased when it is combined with Magnesium hydroxide.Approved
SuccinylcholineMagnesium hydroxide may increase the neuromuscular blocking activities of Succinylcholine.Approved
SulpirideThe serum concentration of Sulpiride can be decreased when it is combined with Magnesium hydroxide.Approved
Technetium Tc-99m medronateThe serum concentration of Technetium Tc-99m Medronate can be decreased when it is combined with Magnesium hydroxide.Approved
TemafloxacinMagnesium hydroxide can cause a decrease in the absorption of Temafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
TetracyclineMagnesium hydroxide can cause a decrease in the absorption of Tetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
ThiethylperazineMagnesium hydroxide can cause a decrease in the absorption of Thiethylperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
ThioridazineMagnesium hydroxide can cause a decrease in the absorption of Thioridazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
Tiludronic acidThe serum concentration of Tiludronate can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
TixocortolThe bioavailability of Tixocortol can be decreased when combined with Magnesium hydroxide.Approved
TolevamerThe risk or severity of adverse effects can be increased when Magnesium hydroxide is combined with Polystyrene sulfonate.Approved
Tolfenamic AcidThe risk or severity of adverse effects can be increased when Tolfenamic Acid is combined with Magnesium hydroxide.Approved
TranilastThe risk or severity of adverse effects can be increased when Tranilast is combined with Magnesium hydroxide.Approved, Investigational
TriamcinoloneThe bioavailability of Triamcinolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
TriethylenetetramineMagnesium hydroxide can cause a decrease in the absorption of Triethylenetetramine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
TrifluoperazineMagnesium hydroxide can cause a decrease in the absorption of Trifluoperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
TriflupromazineMagnesium hydroxide can cause a decrease in the absorption of Triflupromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
TrovafloxacinMagnesium hydroxide can cause a decrease in the absorption of Trovafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
TubocurarineMagnesium hydroxide may increase the neuromuscular blocking activities of Tubocurarine.Approved
UbidecarenoneThe serum concentration of Coenzyme Q10 can be decreased when it is combined with Magnesium hydroxide.Experimental
VecuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Vecuronium.Approved
VerapamilThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium hydroxide.Approved
VinpocetineThe risk or severity of adverse effects can be increased when Vinpocetine is combined with Magnesium hydroxide.Investigational
XylometazolineThe risk or severity of adverse effects can be increased when Xylometazoline is combined with Magnesium hydroxide.Approved
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Magnesium hydroxide.Approved
Zoledronic acidThe serum concentration of Zoledronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
Food InteractionsNot Available
References
Synthesis ReferenceNot Available
General References
  1. Wikipedia [Link]
  2. Drugs.com [Link]
  3. Glow [Link]
  4. Medicines [Link]
  5. Drugs.com [Link]
External Links
ATC CodesA02AA04 — Magnesium hydroxideG04BX01 — Magnesium hydroxide
AHFS CodesNot Available
PDB EntriesNot Available
FDA labelNot Available
MSDSNot Available
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedBasic ScienceHealthy Volunteers3
1CompletedBasic ScienceHuman Immunodeficiency Virus (HIV) Infections1
1CompletedTreatmentAdvanced Solid Tumors1
1CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
1, 2CompletedTreatmentChronic Kidney Disease (CKD) / Hypomagnesaemia1
2CompletedNot AvailableAcid Reflux Disease / GERD / Heartburn / Regurgitation1
3TerminatedTreatmentRadiation-induced Oesophagitis1
4CompletedTreatmentEmergency / Indigestion / Pain1
Not AvailableCompletedPreventionPost Procedural Constipation1
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage forms
FormRouteStrength
OintmentTopical.25 %
OintmentTopical0.25 %
GelOral
Tablet, chewableOral
SuspensionOral1200 mg/15mL
SuspensionOral80 mg/mL
SolutionOral
TabletOral
LiquidOral
SuspensionOral
TabletOral385 mg
LiquidOral400 mg/5mL
EmulsionOral
ConcentrateOral2400 mg/10mL
LiquidOral400 mg
SuspensionOral2400 mg/30mL
SuspensionOral2400 mg/10mL
SuspensionOral400 mg/5mL
SuspensionOral7.75 %
LiquidOral8 g
TabletOral300 mg
SuspensionOral400 mg
SuspensionOral80 mg
SuspensionOral440 mg
Tablet, chewableOral400 mg/1
LiquidOral80 mg
Tablet, chewableOral311 mg/1
LiquidOral2400 mg/15mL
LiquidOral1200 mg/15mL
PricesNot Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US6489346 No1996-07-162016-07-16Us
US6699885 No1996-07-162016-07-16Us
US6645988 No1996-07-162016-07-16Us
US7399772 No1996-07-162016-07-16Us
US6814978 Yes2002-02-262022-02-26Us
US5989588 Yes1998-03-302018-03-30Us
Properties
StateSolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
logP-0.57ChemAxon
pKa (Strongest Acidic)15.7ChemAxon
pKa (Strongest Basic)-1.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET featuresNot Available
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
Taxonomy
DescriptionThis compound belongs to the class of chemical entities known as alkaline earth metal hydroxides. These are inorganic compounds in which the largest oxoanion is hydroxide, and in which the heaviest atom not in an oxoanion is an alkaline earth metal.
KingdomChemical entities
Super ClassInorganic compounds
ClassMixed metal/non-metal compounds
Sub ClassAlkaline earth metal oxoanionic compounds
Direct ParentAlkaline earth metal hydroxides
Alternative ParentsInorganic salts / Inorganic oxides / Inorganic hydrides
SubstituentsAlkaline earth metal hydroxide / Inorganic hydride / Inorganic oxide / Inorganic salt
Molecular FrameworkNot Available
External Descriptorsmagnesium hydroxide (CHEBI:6637 )
Drug created on September 16, 2015 16:26 / Updated on August 08, 2017 11:11