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Identification
NameMagnesium Hydroxide
Accession NumberDB09104
TypeSmall Molecule
GroupsApproved
DescriptionMagnesium hydroxide is an inorganic compound with the chemical formula Mg(OH)2. It is naturally found as the mineral brucite. Magnesium hydroxide can be used an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke supressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as an antiperspirant underarm deodorant or for relief of canker sores (aphthous ulcers).
Structure
Thumb
Synonyms
Magnesium dihydroxide
Milk of magnesia
External Identifiers Not Available
Approved Prescription ProductsNot Available
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-08-05Not applicableUs
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-07-27Not applicableUs
Careone Milk Of MagnesiaSuspension1200 mg/15mLOralAmerican Sales Company2012-08-26Not applicableUs
Dermagran II Ointment - 0.25%Ointment.25 %TopicalTrans Canaderm Inc.1996-01-011996-09-10Canada
Dermagran II Ointment 0.25%Ointment.25 %TopicalCanadian Medical Supply Inc.1993-12-311996-09-09Canada
Dermagran II Ointment-ont Top 0.25%Ointment0.25 %TopicalCanderm G.P.1998-05-072008-08-06Canada
Dg Health Milk Of MagnesiaSuspension1200 mg/15mLOralDolgencorp2014-05-07Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2004-10-14Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2004-10-14Not applicableUs
Equaline Milk Of MagnesiaSuspension1200 mg/15mLOralSupervalu2005-11-14Not applicableUs
Equate Milk Of MagnesiaLiquid1200 mg/15mLOralWalmart Stores2005-04-21Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen1990-04-15Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen1990-02-15Not applicableUs
Good Neighbor Pharmacy Milk Of MagnesiaSuspension1200 mg/15mLOralAmerisource Bergen2005-04-12Not applicableUs
Good Sense Milk Of MagnesiaSuspension1200 mg/15mLOralL. Perrigo Company2005-07-11Not applicableUs
Good Sense Milk Of Magnesia Stimulant FreeSuspension1200 mg/15mLOralL. Perrigo Company1991-06-15Not applicableUs
Good Sense Milk Of Magnesia Stimulant FreeSuspension1200 mg/15mLOralL. Perrigo Company1991-06-15Not applicableUs
Harris Teeter Milk Of MagnesiaSuspension1200 mg/15mLOralHarris Teeter2015-03-30Not applicableUs
Healthy Accents Milk Of MagnesiaSuspension1200 mg/15mLOralDza Brands,2008-01-22Not applicableUs
Healthy Accents Milk Of MagnesiaSuspension1200 mg/15mLOralDza Brands,2008-01-22Not applicableUs
Humco Milk Of MagnesiaSuspension80 mg/mLOralHumco Holding Group. Inc.1998-03-25Not applicableUs
Leader Milk Of MagnesiaLiquid1200 mg/15mLOralCardinal Health2005-01-19Not applicableUs
Leader Milk Of MagnesiaSuspension1200 mg/15mLOralCardinal Health1992-12-01Not applicableUs
Leader Milk Of MagnesiaSuspension1200 mg/15mLOralCardinal Health2014-01-23Not applicableUs
Leader Milk Of Magnesia Saline LaxativeSuspension1200 mg/15mLOralCardinal Health1997-10-21Not applicableUs
MagmexLiquid1200 mg/15mLOralMenper Distributors2012-02-21Not applicableUs
Magnesia TabletsTablet385 mgOralVita Health Products Inc1990-12-312002-08-01Canada
Magnesium HydroxideLiquid400 mg/5mLOralRebel Distributors2010-03-22Not applicableUs
Medibest Milk Of MagnesiaLiquid1200 mg/15mLOralPurine Pharma Llc2016-10-12Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralPhysicians Total Care, Inc.1997-06-19Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralKroger1999-10-20Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health1992-08-07Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee2005-07-18Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWestern Family Foods1992-11-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralSafeway1997-08-19Not applicableUs
Milk Of MagnesiaSuspension2400 mg/30mLOralCardinal Health2011-06-07Not applicableUs
Milk Of MagnesiaLiquid400 mg/5mLOralKinray2014-10-01Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralKroger1999-10-20Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health2005-05-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen1995-11-10Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.1994-10-14Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-24Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralWestern Family Foods2005-07-11Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralPublix Supermarkets, Inc.2005-01-13Not applicableUs
Milk Of MagnesiaSuspension2400 mg/10mLOralCardinal Health2011-06-07Not applicableUs
Milk Of MagnesiaConcentrate2400 mg/10mLOralRemedy Repack2015-09-04Not applicableUs
Milk Of MagnesiaLiquid400 mgOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Milk Of MagnesiaSuspension1200 mg/15mLOralMeijer Distribution1992-08-26Not applicableUs
Milk Of MagnesiaSuspension400 mg/5mLOralPharmaceutical Associates, Inc.1979-09-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralMedicine Shoppe International1991-02-15Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen2013-05-08Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.1992-06-09Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee1997-05-02Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralDiscount Drug Mart2016-01-28Not applicableUs
Milk Of MagnesiaLiquid400 mg/5mLOralRij Pharmaceutical Corporation1999-03-16Not applicableUs
Milk Of MagnesiaSuspension2400 mg/30mLOralLLC Federal Solutions2013-08-12Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralCvs Health1992-08-10Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralMeijer Distribution2004-10-18Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralBetter Living Brands2016-02-04Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWestern Family Foods1992-11-04Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralAurohealth LLC2016-01-28Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralWalgreen2014-10-01Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralH.E.B.2012-10-10Not applicableUs
Milk Of MagnesiaSuspension2400 mg/10mLOralPharmaceutical Associates, Inc.1982-04-20Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralMedicine Shoppe International2003-02-24Not applicableUs
Milk Of MagnesiaConcentrate2400 mg/10mLOralWest Ward Pharmaceutical2001-03-12Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralShopko Stores Operating2013-06-05Not applicableUs
Milk Of MagnesiaSuspension1200 mg/15mLOralHyvee1997-02-05Not applicableUs
Milk Of MagnesiaLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of Magnesia 7% To 8.5%Suspension7.75 %OralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1971-12-311996-09-09Canada
Milk Of Magnesia CherryLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralCvs Health2015-07-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia CherryLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia LiquidLiquid8 gOralD.C. Labs Limited1951-12-312005-07-19Canada
Milk Of Magnesia MintLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia MintLiquid1200 mg/15mLOralMajor2011-06-06Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralWalgreens2010-02-04Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralNash Finch2009-03-20Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralChain Drug Consortium2009-06-03Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralSelect Brand2009-06-03Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralBest Choice2009-07-08Not applicableUs
Milk Of Magnesia MintLiquid1200 mg/15mLOralRugby2011-01-28Not applicableUs
Milk Of Magnesia MintLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Milk Of Magnesia MintSuspension1200 mg/15mLOralAmerican Sales Company2009-03-12Not applicableUs
Milk Of Magnesia MintLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia Mint Flav Tab 385mgTablet385 mgOralShoppers Drug Mart Inc.1978-12-311999-08-11Canada
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralCvs Health2009-05-28Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralNash Finch2009-06-03Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralBest Choice2009-04-02Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralChain Drug Consortium2009-06-03Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralPreferreed Pharmaceuticals Inc.2012-07-26Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralSelect Brand2009-11-03Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralBest Choice2009-04-02Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralAmerican Sales Company2009-04-02Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralGericare Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralDollar General2009-03-23Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralChain Drug Marketing Association2014-04-01Not applicableUs
Milk Of Magnesia OriginalSuspension1200 mg/15mLOralWalgreens2010-02-04Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralAtlantic Biologicals Corps.2010-12-08Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralTYA Pharmaceuticals2000-01-01Not applicableUs
Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMajor2010-12-08Not applicableUs
Milk Of Magnesia Sus 440mg/5ml USPSuspension440 mgOralKsl Pharmaceuticals1995-12-311996-09-09Canada
Milk Of Magnesia Tablets 300mgTablet300 mgOralD.C. Labs Limited1951-12-312005-07-19Canada
Milk Of Magnesia U.S.P. - Sus 400mgSuspension400 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1996-07-162002-07-31Canada
Milk Of Magnesia U.S.P. - Sus 400mg/5mlSuspension400 mgOralKsl Pharmaceuticals1996-12-311998-08-13Canada
Milk Of Magnesia USPSuspension80 mgOralBdh Inc.1995-12-312000-08-03Canada
Milk Of Magnesia USP Sus 440mg/5mlSuspension440 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-311997-08-08Canada
Milk Of Magnesia Wild CherrySuspension1200 mg/15mLOralH.E.B.2010-03-02Not applicableUs
Milk Of Magnesia Wild CherrySuspension1200 mg/15mLOralChain Drug Consortium2010-01-08Not applicableUs
Milk Of Magnesia-sus 400mg/5mlSuspension400 mgOralDruggists' Corporation1995-12-311997-08-12Canada
Mint Milk Of MagnesiaSuspension1200 mg/15mLOralPublix Supermarkets, Inc.1994-09-02Not applicableUs
OriginalSuspension1200 mg/15mLOralPublix Supermarkets, Inc.1994-09-02Not applicableUs
Pedia-laxTablet, chewable400 mg/1OralC.B. Fleet Company, Inc.2008-03-01Not applicableUs
Phillip's Milk Of Magnesia Liq 80mg/ml PlainLiquid80 mgOralSterling Winthrop Inc.1992-12-311996-09-10Canada
Phillips ChewableTablet, chewable311 mg/1OralBayer2014-12-04Not applicableUs
Phillips Fresh Mint Milk Of MagnesiaLiquid1200 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-16Not applicableUs
Phillips Milk Of Magnesia Concentrated Fresh StrawberryLiquid2400 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-18Not applicableUs
Phillips Milk Of Magnesia Wild CherryLiquid1200 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-17Not applicableUs
Phillips Original Milk Of MagnesiaLiquid1200 mg/15mLOralBayer Health Care Llc, Consumer Care2014-12-16Not applicableUs
Shoprite Milk Of MagnesiaSuspension1200 mg/15mLOralWakfern Food Corporation2015-04-29Not applicableUs
Shoprite Milk Of MagnesiaSuspension1200 mg/15mLOralWakfern Food Corporation2015-04-29Not applicableUs
Sound Body Milk Of MagnesiaSuspension1200 mg/15mLOralBig Lots Stores, Inc.2016-03-24Not applicableUs
Stratuscare Milk Of MagnesiaSuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Stratuscare Milk Of Magnesia CherrySuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Stratuscare Milk Of Magnesia Sugar FreeSuspension1200 mg/15mLOralStratus Pharmaceuticals2014-05-26Not applicableUs
Sunmark Milk Of MagnesiaLiquid1200 mg/15mLOralMc Kesson2003-08-21Not applicableUs
Sunmark Milk Of MagnesiaLiquid1200 mg/15mLOralMc Kesson2003-08-21Not applicableUs
Sunmark Milk Of Magnesia MintLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Sunmark Milk Of Magnesia OriginalLiquid1200 mg/15mLOralMc Kesson2012-04-01Not applicableUs
Sunmark Milk Of Magnesia Saline LaxativeLiquid1200 mg/15mLOralMc Kesson2005-02-11Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates2006-02-20Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates1993-01-13Not applicableUs
Topcare Milk Of MagnesiaSuspension1200 mg/15mLOralTopco Associates1991-09-10Not applicableUs
Unapproved/Other Products Not Available
International BrandsNot Available
Brand mixtures
NameLabellerIngredients
Acid Controller CompleteSafeway
Acid Controller Complete Dual ActionWalgreen
Acid Reducer CompleteRite Aid
Acid Reducer Plus AntacidRite Aid
Acidex Tc Oral SuspensionGen Drug Company Ltd.
Advanced Antacid CherryMc Kesson
Advanced Antacid Regular StrengthSunmark (Mckesson)
AlmaconeRugby
Almacone Antacid AntigasRugby
Almacone Double StrengthRugby
Almagel Plus SusLaboratoire Atlas Inc
Aluminum Hydroxide, Magnesium Hydroxide, SimethiconeLLC Federal Solutions
AlumoxGuardian Drug Company
Amphojel 500 SuspensionAxcan Pharma
Amphojel Plus SuspensionAxcan Pharma
AntacidWalgreen
Antacid - Alumina and Magnesia Oral Suspension USPD.C. Labs Limited
Antacid & AntigasGericare Pharmaceuticals
Antacid and AntigasRij Pharmaceutical Corporation
Antacid Anti-gasCvs Health
Antacid AntigasSelect Brand
Antacid Antigas Maximum StrengthSelect Brand
Antacid Antigas Maximum Strength MintCvs Health
Antacid Cherry FlavoredRij Pharmaceutical Corporation
Antacid Chewable TabKsl Pharmaceuticals
Antacid Double StrengthRij Pharmaceutical Corporation
Antacid Liquid Max Strength CherryCvs Health
Antacid Liquid MintCvs Health
Antacid Liquid SuspShoppers Drug Mart Inc.
Antacid Magnesia and AluminaStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Antacid Maximum StrengthMeijer Distribution
Antacid MintSelect Brand
Antacid Mint FlavoredRij Pharmaceutical Corporation
Antacid Plus - SusWes Pak Products Ltd.
Antacid Plus AntiflatuentStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Antacid Plus AntiflatulentKsl Pharmaceuticals
Antacid Plus Antiflatulent - Alumina, Magnesia & Simethicone Oral SuspensionD.C. Labs Limited
Antacid Plus Gas ReliefSafeway
Antacid Plus Gas Relief Regular StrengthSafeway
Antacid Regular StrengthKroger
Antacid Regular With Anti-gasJamp Pharma Corporation
Antacid SupremeCvs Health
Antacid Supreme CherryAaron Industries, Inc.
Antacid SusKsl Pharmaceuticals
Antacid With Alumina, Magnesia Plus Simethicone Oral Suspension USPJamp Pharma Corporation
Antacid With Anti-gas Liquid Extra Strength Mint FlavourPharmetics (2011) Inc.
Antiacide Avec Antiflatulent SusTherapex Division De E Z Em Canada Inc
Antiacide SusProduits Marc O (1987) Inc., Division Of Technilab Inc.
Babys Own Tummy TabG.T. Fulford Pharmaceuticals
Berkley and Jensen Acid Controller CompleteBJWC
C2 Buffered TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
C2 Buffered With Codeine TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
Care One Acid Reducer and Antacid Dual ActionAmerican Sales Company
Care One Acid Reducer Plus Antacid Dual ActionAmerican Sales Company
Careone Acid Reducer CompleteAmerican Sales Company
Careone AntacidAmerican Sales Company
Careone Antacid Regular StrengthAmerican Sales Company
Careone Liquid AntacidAmerican Sales Company
Centra Acid Plus-susTherapex Division De E Z Em Canada Inc
Centra Acid-susTherapex Division De E Z Em Canada Inc
CompleteKroger
Complete Dual ActionHyvee
Conrx ArEagle Distributors,Inc.
Dg Health AntacidDolgencorp
Dg Health Dual Action CompleteDolgencorp
Diovol EX TabCarter Horner Corp.
Diovol Plus AF - TabChurch & Dwight Company, Inc.
Diovol Plus AF-suspensionChurch & Dwight Company, Inc.
Diovol Plus SuspensionChurch & Dwight Company, Inc.
Dual ActionPublix Supermarkets, Inc.
Dual Action CompleteKroger
Duo FusionBoehringer Ingelheim
EnoBelmora LLC
Equaline AntacidSupervalu
Equaline Antacid Regular StrengthSupervalu
Equaline Complete Dual ActionSupervalu
Equate Acid Reducer CompleteWalmart Stores
Equate Antacid Maximum StrengthWalmart Stores
Equate Antacid Regular StrengthWalmart Stores
Exchange Select Antacid Regular StrengthArmy + Air Force Exchange Service
Family Wellness Acid Controller CompleteFamily Dollar Services
Flanax AntacidBelmora LLC
Flanax Antacid Anti-gasBelmora LLC
Gaviscon Acid Relief Fmla Plus Gas Rel. TabSterling Winthrop Inc.
Gaviscon Acid Relief Fmla Plus Gas Rel.liq.Sterling Winthrop Inc.
Gaviscon Acid Relief Formula Extra StrengthSterling Winthrop Inc.
Gaviscon Acid Relief Formula LiquidSterling Winthrop Inc.
Gaviscon Acid Relief Formula TabletsSterling Winthrop Inc.
Gelfos MBoryung Pharmaceutical Co., Ltd
GelusilWell Spring Pharmaceutical Corporation
Gelusil Antacid & Anti-gasBoyd Pharmaceuticals Inc.
Gelusil Extra Strength LiqWarner Lambert Canada Inc.
Gelusil Extra Strength TabletsWell Spring Pharmaceutical Corporation
Gelusil Liquid SusPfizer Canada Inc., Consumer Healthcare Division
Gelusil Maximum StrengthWell Spring Pharmaceutical Corporation
Geri-lanta Antacid AntigasGericare Pharmaceuticals
Geri-lanta Maximum StrengthGericare Pharmaceuticals
Geri-lanta Supreme CherryGericare Pharmaceuticals
Geri-mox Antacid AntigasGericare Pharmaceuticals
Geri-mox Max CherryGericare Pharmaceuticals
Good Neighbor Pharmacy AntacidAmerisource Bergen
Good Neighbor Pharmacy Antacid Regular StrengthAmerisource Bergen
Good Neighbor Pharmacy CompleteAmerisource Bergen
Good Neighbor Pharmacy Dual Action CompleteAmerisource Bergen
Good Sense AntacidL. Perrigo Company
Good Sense Antacid Maximum StrengthL. Perrigo Company
Good Sense Antacid Regular StrengthL. Perrigo Company
Good Sense CompleteL. Perrigo Company
Good Sense Dual Action CompleteL. Perrigo Company
Harris Teeter AntacidHarris Teeter
Harris Teeter Antacid Maximum StrengthHarris Teeter
Harris Teeter Antacid Regular StrengthHarris Teeter
Health Mart AntacidMc Kesson
Health Mart CompleteMc Kesson
Health Mart Dual Action CompleteMc Kesson
Healthy Accents AntacidDza Brands,
Healthy Accents Famotidine Calcium Carbonate Magnesium HydroxideDza Brands,
Healthy Accents MaldroxalDza Brands,
Indigel Plus LiquidProduits Francais Labs Inc.
Inon AceSato Pharmaceutical
Leader Acid Reducer CompleteCardinal Health
Leader Antacid Maximum StrengthCardinal Health
Leader Antacid Regular StrengthCardinal Health
Leader Antacidregular Strength Regular StrengthRemedy Repack
Maalox Advanced Antacid & AntigasNovartis
Maalox Advanced Extra Strength Antacid & AntigasNovartis
Maalox Advanced Maximum Strength CherryNovartis
Maalox Advanced Maximum Strength MintNovartis
Maalox Advanced Maximum Strength Wild BerryNovartis
Maalox Advanced Regular Strength MintNovartis
Maalox AntacidPhysicians Total Care, Inc.
Maalox Plus Extra Strength (cherry)Rhone Poulenc Rorer
Maalox Plus Extra Strength TabletsNovartis
Maalox Plus Suspension Extra StrengthRhone Poulenc Rorer
Maalox Plus Suspension FlavourNovartis
Maalox Plus TabRhone Poulenc Rorer
Maalox Plus TabletsNovartis
Maalox Plus Tablets Lemon FlavourRhone Poulenc Rorer
Maalox Plus Tablets Mint FlavourRhone Poulenc Rorer
Maalox SuspensionNovartis
Maalox TabletRhone Poulenc Rorer
Maalox TabletsNovartis
Maalox Tablets Cherry FlavourCiba Self Medication
Maalox Tablets Mint FlavourCiba Self Medication
Maalox Tc SuspensionRhone Poulenc Rorer
Maalox Tc TabletRhone Poulenc Rorer
Mag-ALCardinal Health
Mag-AL LiquidPharmaceutical Associates, Inc.
Mag-AL PlusPharmaceutical Associates, Inc.
Mag-AL Plus XsPharmaceutical Associates, Inc.
MagnolaxPendopharm Division Of De Pharmascience Inc
MagsilFortune Pharmacal Company Limited
Maximum Strength AntacidMc Kesson
Maximum Strength Antacid Anti GasPublix Supermarkets, Inc.
Maximum Strength Antacid MintCvs Health
Medique Alamag PlusUnifirst First Aid
Mi AcidMajor
Mi-acid Maximum StrengthMajor
Mi-acid Regular StrengthMajor
Milk Of Magnesia Mineral Oil EmulsionMeta Pharmaceuticals Inc.
MintoxMajor
Mintox Maximum StrengthMajor
Mintox Plus TabsMajor
Mucaine - SusAurium Pharma Inc
Mylanta Liquid Extra Strength SusPfizer Canada Inc., Consumer Healthcare Division
Mylanta Liquid Regular Strength SusPfizer Canada Inc., Consumer Healthcare Division
Mylanta Maximum Strength Classic FlavorInfirst Healthcare
Mylanta Maximum Strength Vanilla Caramel FlavorInfirst Healthcare
Mylanta New Tonight Soothing Honey ChamomileInfirst Healthcare
Mylanta Plain Liq Double StrengthParke Davis Division, Warner Lambert Canada Inc.
Mylanta Plain Liq Double Strength SusPfizer Canada Inc., Consumer Healthcare Division
Mylanta Tablets Double StrengthMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Mylanta Tablets Regular StrengthMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Neutralca S SusDesbergers LtÉe, Division Of Technilab Inc.
Neutralca S TabDesbergers LtÉe, Division Of Technilab Inc.
Pepcid CompleteMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
Phillips Dual ActionBayer Inc Consumer Care
PMS-alumina Mag and Simethicone SusPharmascience Inc
Preferred Plus CompleteKinray
Regular Strength AntacidChain Drug Marketing Association
Regular Strength Antacid Anti GasPublix Supermarkets, Inc.
Regular Strength Antacid MintCvs Health
Rexall Antacid AdvancedDolgencorp
Ri MoxRij Pharmaceutical Corporation
RolaidsAdams Canada, Division Of Warner Lambert Canada Inc.
Rolaids Advanced Antacid Anti-gas Mixed BerryChattem, Inc.
Rolaids Extra Strength FruitChattem, Inc.
Rolaids Extra Strength MintChattem, Inc.
Rolaids Regular Strength MintChattem, Inc.
Rolaids Regular Strength- CherryChattem, Inc.
Rolaids Regular Strength- MintChattem, Inc.
Rolaids Ultra Strength Antacid OrangeChattem, Inc.
Rolaids Ultra Strength Antacid StrawberryChattem, Inc.
Rolaids Ultra Strength FruitChattem, Inc.
Rolaids Ultra Strength MintChattem, Inc.
Rolaids Ultra Strength- CherryChattem, Inc.
Rolaids Ultra Strength- MintChattem, Inc.
Rulox RegularRugby
Rx Act Antacid Regular StrengthH.E.B.
Shoprite CompleteWakfern Food Corporation
Shoprite Dual Action CompleteWakfern Food Corporation
Signature Care Acid Controller CompleteSafeway
Signature Care Acid Reducer CompleteSafeway
Signature Care Antacid Plus Gas ReliefSafeway
Simply Right Famotidine CompleteSam's West, Inc
Smart Sense AntacidKmart Corporation
Smart Sense CompleteKmart Corporation
Smart Sense Dual Action CompleteKmart Corporation
StomaaxTheralab Inc.
Stomaax PlusLaboratoire Atlas Inc
Stratuscare Antacid and AntigasStratus Pharmaceuticals
Stratuscare Antacid and Antigas Regular StrengthStratus Pharmaceuticals
Sunmark AntacidMc Kesson
Sunmark Antacid Maximum StrengthMc Kesson
Sunmark Antacid Maximum Strength CherryMc Kesson
Sunmark CompleteMc Kesson
Sunmark Dual Action CompleteMc Kesson
Topcare AntacidTopco Associates
Topcare Antacid Maximum StrengthTopco Associates
Topcare Antacid Plus Anti GasTopco Associates
Topcare Antacid Regular StrengthTopco Associates
Topcare CompleteTopco Associates
Topcare Complete Acid Reducer Plus AntacidTopco Associates
Topcare Dual Action CompleteTopco Associates
Univol SuspensionCarter Horner Corp.
Up and Up Acid Controller Complete Dual ActionTarget Corporation.
Up and Up Antacid Anti Gas Regular StrengthTarget Corporation.
Up and Up Dual Action Acid Controller CompleteTarget Corporation.
Up and Up Famotidine CompleteTarget Corporation.
SaltsNot Available
Categories
UNIINBZ3QY004S
CAS number1309-42-8
WeightAverage: 58.32
Monoisotopic: 57.990521206
Chemical FormulaH2MgO2
InChI KeyVTHJTEIRLNZDEV-UHFFFAOYSA-L
InChI
InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2
IUPAC Name
magnesium(2+) ion dihydroxide
SMILES
[OH-].[OH-].[Mg++]
Pharmacology
IndicationMagnesium hydroxide can be used as an antacid or a laxative depending on the administered dose. As an antacid, it is used for the temporary relief of heartburn, upset stomach, sour stomach or acid indigestion. As a laxative, it is used for the relief of occasional constipation by promoting bowel movements for 30 minutes and up to 6 hours.
Structured Indications
PharmacodynamicsAs an antacid, magnesium hydroxide suspension neutralizes gastric acid by reacting with hydrochloric acid in the stomach to form magnesium chloride and water. It is practically insoluble in water and does not have any effect until it reacts with the hydrochloric acid in the stomach. There, it decreases the direct acid irritant effect and increases the pH in the stomach leading to inactivation of pepsin. Magnesium hydroxide enhances the integrity of the mucosal barrier of the stomach as well as improving the tone of both the gastric and esophageal sphincters. As a laxative, the magnesium hydroxide works by increasing the osmotic effect in the intestinal tract and drawing water in. This creates distension of the colon which results in an increase in peristaltic movement and bowel evacuation.
Mechanism of actionThe suspension of magnesium hydroxide is ingested and enters the stomach. According to the amount ingested, the magnesium hydroxide will either act as an antacid or a laxative. Through the ingestion of 0.5-1.5 grams (in adults) the magnesium hydroxide will act by simple acid neutralization in the stomach. The hydroxide ions from the magnesium hydroxide suspension will combine with the acidic H+ ions of the hydrochloric acid made by the stomachs parietal cells. This neutralization reaction will result in the formation of magnesium chloride and water. Through the ingestion of 2-5 grams (in adults) the magnesium hydroxide acts as a laxative in the colon. The majority of the suspension is not absorbed in the intestinal tract and will create an osmotic effect to draw water into the gut from surrounding tissues. With this increase of water in the intestines, the feces will soften and the intraluminal volume of the feces will increase. These effects still stimulate intestinal motility and induce the urge to defecate. Magnesium hydroxide will also release cholecystokinin (CKK) in the intestines which will accumulate water and electrolytes in the lumen and furthermore increase intestinal motility.
Related Articles
AbsorptionAbout 15%-50% of magnesium hydroxide is absorbed very slowly through the small intestine.
Volume of distribution

The peak action and distribution of magnesium hydroxide are variable.

Protein bindingMagnesium hydroxide does not have any protein binding properties.
Metabolism

Unless a patient is deficient in magnesium, very little is absorbed by the intestine. Overall, about 15%-50% of the magnesium hydroxide suspension is absorbed systemically. However, it does not undergo any metabolism as it is rapidly excreted in the urine.

Route of eliminationAfter oral administration, up to 50% of the magnesium hydroxide suspension may be absorbed as magnesium ions through the small intestines and then rapidly excreted in the urine through the kidneys. The unabsorbed drug is mainly excreted in the feces and saliva.
Half lifeN/A
Clearance

Magnesium hydroxide is mainly excreted in the urine by the kidneys. Since the kidneys play a major role in its clearance, individuals with renal failure are at risk of hypermagnesemia with long term consumption as the appropriate amounts of magnesium may not be excreted.

ToxicityLD50=8500 mg/kg (rat, oral) Common side effects include drowsiness or flushing (warmth, redness or tingly feeling). Daily use of magnesium hydroxide can result in fluid and electrolyte disturbances. Excessive use of the laxative effects of magnesium hydroxide may result in abdominal cramping, nausea and/or diarrhea. In overdose, symptoms of gastrointestinal irritation and/or watery diarrhea may occur. Magnesium hydroxide poisoning can result in hypermagnesemia which includes symptoms of: nausea, vomiting, flushing, thirst, hypotension, drowsiness, confusion, loss of tendon reflexes, muscle weakness, respiratory depression, cardiac arrhythmias, coma and cardiac arrest. Not to be used in individuals with any form of kidney disease or renal failure, a magnesium restricted diet or with any sudden changes in bowel movement lasting over two weeks. Also not to be used in those individuals with abdominal pain, nausea, vomiting, symptoms of appendicitis or myocardial damage, heart block, fecal impaction, rectal fissures, intestinal obstruction or perforation or renal disease. Not to be used in women who are about to deliver as magnesium crosses the placenta and is excreted in small amounts in breast milk. Using magnesium hydroxide with aluminum hydroxide can decrease the absorption rate of these drugs. Magnesium hydroxide can react with digoxin, dicoumerol and cimetidine. Use of ibuprofen with magnesium hydroxide can increase the absorption of the ibuprofen. Use of magnesium hydroxide with penicallamine, bisphosphates, ketoconazole, quinolones or tetracycline can decrease the absorption of these drugs. Enteric-coated tablets can be prematurely released when taken with magnesium hydroxide. It is important to routinely monitor levels of serum magnesium and potassium in patients using magnesium hydroxide. Serum magnesium levels are necessary to determine how much magnesium is being absorbed and how much is being excreted by the kidneys. Excessive diarrhea can occur from use of magnesium hydroxide and thus it is important to also monitor serum potassium levels to ensure hypokalemia does not occur.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
16-BromoepiandrosteroneThe bioavailability of 16-Bromoepiandrosterone can be decreased when combined with Magnesium hydroxide.Investigational
19-norandrostenedioneThe bioavailability of 19-norandrostenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
2,5-Dimethoxy-4-ethylamphetamineMagnesium hydroxide may decrease the excretion rate of 2,5-Dimethoxy-4-ethylamphetamine which could result in a higher serum level.Experimental, Illicit
3,4-MethylenedioxyamphetamineMagnesium hydroxide may decrease the excretion rate of 3,4-Methylenedioxyamphetamine which could result in a higher serum level.Experimental, Illicit
3,4-MethylenedioxymethamphetamineMagnesium hydroxide may decrease the excretion rate of 3,4-Methylenedioxymethamphetamine which could result in a higher serum level.Experimental, Illicit
4-AndrostenedioneThe bioavailability of 4-Androstenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamineMagnesium hydroxide may decrease the excretion rate of 4-Bromo-2,5-dimethoxyamphetamine which could result in a higher serum level.Experimental, Illicit
5-androstenedioneThe bioavailability of 5-androstenedione can be decreased when combined with Magnesium hydroxide.Experimental, Illicit
AcepromazineMagnesium hydroxide can cause a decrease in the absorption of Acepromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
AceprometazineMagnesium hydroxide can cause a decrease in the absorption of Aceprometazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
AlclometasoneThe bioavailability of Alclometasone can be decreased when combined with Magnesium hydroxide.Approved
AldosteroneThe bioavailability of Aldosterone can be decreased when combined with Magnesium hydroxide.Experimental
Alendronic acidThe serum concentration of Alendronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
AlfacalcidolThe serum concentration of Magnesium hydroxide can be increased when it is combined with Alfacalcidol.Approved, Nutraceutical
AlimemazineMagnesium hydroxide can cause a decrease in the absorption of Alimemazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
AllopurinolMagnesium hydroxide can cause a decrease in the absorption of Allopurinol resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
AmcinonideThe bioavailability of Amcinonide can be decreased when combined with Magnesium hydroxide.Approved
AmlodipineThe risk or severity of adverse effects can be increased when Amlodipine is combined with Magnesium hydroxide.Approved
AmphetamineMagnesium hydroxide may decrease the excretion rate of Amphetamine which could result in a higher serum level.Approved, Illicit
AmrinoneThe risk or severity of adverse effects can be increased when Amrinone is combined with Magnesium hydroxide.Approved
AnecortaveThe bioavailability of Anecortave can be decreased when combined with Magnesium hydroxide.Investigational
AtazanavirMagnesium hydroxide can cause a decrease in the absorption of Atazanavir resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
AtorvastatinThe serum concentration of Atorvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
Atracurium besylateMagnesium hydroxide may increase the neuromuscular blocking activities of Atracurium besylate.Approved
AzelnidipineThe risk or severity of adverse effects can be increased when Azelnidipine is combined with Magnesium hydroxide.Approved
AzimilideThe risk or severity of adverse effects can be increased when Azimilide is combined with Magnesium hydroxide.Investigational
BarnidipineThe risk or severity of adverse effects can be increased when Barnidipine is combined with Magnesium hydroxide.Approved
BeclomethasoneThe bioavailability of Beclomethasone can be decreased when combined with Magnesium hydroxide.Investigational
Beclomethasone dipropionateThe bioavailability of Beclomethasone dipropionate can be decreased when combined with Magnesium hydroxide.Approved, Investigational
BenidipineThe risk or severity of adverse effects can be increased when Benidipine is combined with Magnesium hydroxide.Approved
BenzphetamineMagnesium hydroxide may decrease the excretion rate of Benzphetamine which could result in a higher serum level.Approved, Illicit
BepridilThe risk or severity of adverse effects can be increased when Bepridil is combined with Magnesium hydroxide.Approved, Withdrawn
BetamethasoneThe bioavailability of Betamethasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
BisacodylThe therapeutic efficacy of Bisacodyl can be decreased when used in combination with Magnesium hydroxide.Approved
Bismuth SubcitrateThe therapeutic efficacy of Bismuth Subcitrate can be decreased when used in combination with Magnesium hydroxide.Approved
BL-1020Magnesium hydroxide can cause a decrease in the absorption of BL-1020 resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
BosutinibThe serum concentration of Bosutinib can be decreased when it is combined with Magnesium hydroxide.Approved
BudesonideThe bioavailability of Budesonide can be decreased when combined with Magnesium hydroxide.Approved
CaiThe risk or severity of adverse effects can be increased when Cai is combined with Magnesium hydroxide.Investigational
CalcitriolThe serum concentration of Magnesium hydroxide can be increased when it is combined with Calcitriol.Approved, Nutraceutical
CaptoprilThe serum concentration of Captopril can be decreased when it is combined with Magnesium hydroxide.Approved
CefditorenThe serum concentration of Cefditoren can be decreased when it is combined with Magnesium hydroxide.Approved
CefpodoximeThe serum concentration of Cefpodoxime can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
CefuroximeThe serum concentration of Cefuroxime can be decreased when it is combined with Magnesium hydroxide.Approved
CerivastatinThe serum concentration of Cerivastatin can be decreased when it is combined with Magnesium hydroxide.Withdrawn
ChloroquineThe serum concentration of Chloroquine can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
ChlorphentermineMagnesium hydroxide may decrease the excretion rate of Chlorphentermine which could result in a higher serum level.Illicit, Withdrawn
ChlorpromazineMagnesium hydroxide can cause a decrease in the absorption of Chlorpromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
ChlortetracyclineMagnesium hydroxide can cause a decrease in the absorption of Chlortetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
CiclesonideThe bioavailability of Ciclesonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
CilnidipineThe risk or severity of adverse effects can be increased when Cilnidipine is combined with Magnesium hydroxide.Approved
CinnarizineThe risk or severity of adverse effects can be increased when Cinnarizine is combined with Magnesium hydroxide.Approved
CinoxacinMagnesium hydroxide can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
CiprofloxacinMagnesium hydroxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
Cisatracurium besylateMagnesium hydroxide may increase the neuromuscular blocking activities of Cisatracurium besylate.Approved
ClevidipineThe risk or severity of adverse effects can be increased when Clevidipine is combined with Magnesium hydroxide.Approved
ClobetasolThe bioavailability of Clobetasol can be decreased when combined with Magnesium hydroxide.Investigational
Clobetasol propionateThe bioavailability of Clobetasol propionate can be decreased when combined with Magnesium hydroxide.Approved
ClocortoloneThe bioavailability of Clocortolone can be decreased when combined with Magnesium hydroxide.Approved
ClodronateThe serum concentration of Clodronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
Coenzyme Q10The serum concentration of Coenzyme Q10 can be decreased when it is combined with Magnesium hydroxide.Experimental
Cortisone acetateThe bioavailability of Cortisone acetate can be decreased when combined with Magnesium hydroxide.Approved
CysteamineThe therapeutic efficacy of Cysteamine can be decreased when used in combination with Magnesium hydroxide.Approved, Investigational
Dabigatran etexilateThe serum concentration of Dabigatran etexilate can be decreased when it is combined with Magnesium hydroxide.Approved
DabrafenibThe serum concentration of Dabrafenib can be decreased when it is combined with Magnesium hydroxide.Approved
DarodipineThe risk or severity of adverse effects can be increased when Darodipine is combined with Magnesium hydroxide.Experimental
DasatinibMagnesium hydroxide can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
DecamethoniumMagnesium hydroxide may increase the neuromuscular blocking activities of Decamethonium.Approved
DeferiproneThe serum concentration of Deferiprone can be decreased when it is combined with Magnesium hydroxide.Approved
dehydroepiandrosterone sulfateThe bioavailability of dehydroepiandrosterone sulfate can be decreased when combined with Magnesium hydroxide.Investigational
DelavirdineThe serum concentration of Delavirdine can be decreased when it is combined with Magnesium hydroxide.Approved
DemeclocyclineMagnesium hydroxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
DesoximetasoneThe bioavailability of Desoximetasone can be decreased when combined with Magnesium hydroxide.Approved
Desoxycorticosterone acetateThe bioavailability of Desoxycorticosterone acetate can be decreased when combined with Magnesium hydroxide.Approved
Desoxycorticosterone PivalateThe bioavailability of Desoxycorticosterone Pivalate can be decreased when combined with Magnesium hydroxide.Experimental, Vet Approved
DexamethasoneThe bioavailability of Dexamethasone can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
Dexamethasone isonicotinateThe bioavailability of Dexamethasone isonicotinate can be decreased when combined with Magnesium hydroxide.Vet Approved
DexmethylphenidateMagnesium hydroxide can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.Approved
DextroamphetamineMagnesium hydroxide may decrease the excretion rate of Dextroamphetamine which could result in a higher serum level.Approved, Illicit
DiethylpropionMagnesium hydroxide may decrease the excretion rate of Diethylpropion which could result in a higher serum level.Approved, Illicit
DiflorasoneThe bioavailability of Diflorasone can be decreased when combined with Magnesium hydroxide.Approved
DifluocortoloneThe bioavailability of Difluocortolone can be decreased when combined with Magnesium hydroxide.Approved
DifluprednateThe bioavailability of Difluprednate can be decreased when combined with Magnesium hydroxide.Approved
DiltiazemThe risk or severity of adverse effects can be increased when Diltiazem is combined with Magnesium hydroxide.Approved
Dipotassium phosphateThe serum concentration of Dipotassium phosphate can be decreased when it is combined with Magnesium hydroxide.Approved
DolutegravirThe serum concentration of Dolutegravir can be decreased when it is combined with Magnesium hydroxide.Approved
Domoic AcidMagnesium hydroxide may increase the neuromuscular blocking activities of Domoic Acid.Experimental
DotarizineThe risk or severity of adverse effects can be increased when Dotarizine is combined with Magnesium hydroxide.Investigational
Doxacurium chlorideMagnesium hydroxide may increase the neuromuscular blocking activities of Doxacurium chloride.Approved
DoxycyclineMagnesium hydroxide can cause a decrease in the absorption of Doxycycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational, Vet Approved
EfonidipineThe risk or severity of adverse effects can be increased when Efonidipine is combined with Magnesium hydroxide.Approved
EltrombopagThe serum concentration of Eltrombopag can be decreased when it is combined with Magnesium hydroxide.Approved
ElvitegravirThe serum concentration of Elvitegravir can be decreased when it is combined with Magnesium hydroxide.Approved
EnoxacinMagnesium hydroxide can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
EperisoneThe risk or severity of adverse effects can be increased when Eperisone is combined with Magnesium hydroxide.Approved, Investigational
EquileninThe bioavailability of Equilenin can be decreased when combined with Magnesium hydroxide.Experimental
EquilinThe bioavailability of Equilin can be decreased when combined with Magnesium hydroxide.Approved
ErlotinibThe serum concentration of Erlotinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
EstroneThe bioavailability of Estrone can be decreased when combined with Magnesium hydroxide.Approved
Estrone sulfateThe bioavailability of Estrone sulfate can be decreased when combined with Magnesium hydroxide.Approved
Etidronic acidThe serum concentration of Etidronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
FelodipineThe risk or severity of adverse effects can be increased when Felodipine is combined with Magnesium hydroxide.Approved, Investigational
FendilineThe risk or severity of adverse effects can be increased when Fendiline is combined with Magnesium hydroxide.Withdrawn
Ferric CarboxymaltoseMagnesium hydroxide can cause a decrease in the absorption of Ferric Carboxymaltose resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Ferric CitrateMagnesium hydroxide can cause a decrease in the absorption of Ferric Citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Ferric pyrophosphateMagnesium hydroxide can cause a decrease in the absorption of Ferric pyrophosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
FexofenadineThe serum concentration of Fexofenadine can be decreased when it is combined with Magnesium hydroxide.Approved
FleroxacinMagnesium hydroxide can cause a decrease in the absorption of Fleroxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
fluasteroneThe bioavailability of fluasterone can be decreased when combined with Magnesium hydroxide.Investigational
FludrocortisoneThe bioavailability of Fludrocortisone can be decreased when combined with Magnesium hydroxide.Approved
FlumequineMagnesium hydroxide can cause a decrease in the absorption of Flumequine resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
FlumethasoneThe bioavailability of Flumethasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Magnesium hydroxide.Approved
FlunisolideThe bioavailability of Flunisolide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
Fluocinolone AcetonideThe bioavailability of Fluocinolone Acetonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Vet Approved
FluocinonideThe bioavailability of Fluocinonide can be decreased when combined with Magnesium hydroxide.Approved, Investigational
FluocortoloneThe bioavailability of Fluocortolone can be decreased when combined with Magnesium hydroxide.Approved, Withdrawn
FluorometholoneThe bioavailability of Fluorometholone can be decreased when combined with Magnesium hydroxide.Approved
FluphenazineMagnesium hydroxide can cause a decrease in the absorption of Fluphenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
FluprednideneThe bioavailability of Fluprednidene can be decreased when combined with Magnesium hydroxide.Approved, Withdrawn
FluprednisoloneThe bioavailability of Fluprednisolone can be decreased when combined with Magnesium hydroxide.Approved
FlurandrenolideThe bioavailability of Flurandrenolide can be decreased when combined with Magnesium hydroxide.Approved
Fluticasone furoateThe bioavailability of Fluticasone furoate can be decreased when combined with Magnesium hydroxide.Approved
Fluticasone PropionateThe bioavailability of Fluticasone Propionate can be decreased when combined with Magnesium hydroxide.Approved
FluvastatinThe serum concentration of Fluvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
FormestaneThe bioavailability of Formestane can be decreased when combined with Magnesium hydroxide.Approved, Investigational, Withdrawn
FosinoprilThe serum concentration of Fosinopril can be decreased when it is combined with Magnesium hydroxide.Approved
GabapentinMagnesium hydroxide may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.Approved, Investigational
Gallamine TriethiodideMagnesium hydroxide may increase the neuromuscular blocking activities of Gallamine Triethiodide.Approved
GallopamilThe risk or severity of adverse effects can be increased when Gallopamil is combined with Magnesium hydroxide.Investigational
GarenoxacinMagnesium hydroxide can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
GatifloxacinMagnesium hydroxide can cause a decrease in the absorption of Gatifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
GefitinibThe serum concentration of Gefitinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
GemifloxacinMagnesium hydroxide can cause a decrease in the absorption of Gemifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
GrepafloxacinMagnesium hydroxide can cause a decrease in the absorption of Grepafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
HE3286The bioavailability of HE3286 can be decreased when combined with Magnesium hydroxide.Investigational
HexamethylenetetramineThe therapeutic efficacy of Hexamethylenetetramine can be decreased when used in combination with Magnesium hydroxide.Approved, Vet Approved
HydrocortisoneThe bioavailability of Hydrocortisone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
HydroxyamphetamineMagnesium hydroxide may decrease the excretion rate of Hydroxyamphetamine hydrobromide which could result in a higher serum level.Approved
HyoscyamineThe serum concentration of Hyoscyamine can be decreased when it is combined with Magnesium hydroxide.Approved
IbandronateThe serum concentration of Ibandronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
IronMagnesium hydroxide can cause a decrease in the absorption of Iron resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Iron DextranMagnesium hydroxide can cause a decrease in the absorption of Iron Dextran resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
Iron saccharateMagnesium hydroxide can cause a decrease in the absorption of Iron saccharate resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
IsoniazidMagnesium hydroxide can cause a decrease in the absorption of Isoniazid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
IsradipineThe risk or severity of adverse effects can be increased when Isradipine is combined with Magnesium hydroxide.Approved
IstaroximeThe bioavailability of Istaroxime can be decreased when combined with Magnesium hydroxide.Investigational
ItraconazoleThe serum concentration of Itraconazole can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
KetoconazoleThe serum concentration of Ketoconazole can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
LacidipineThe risk or severity of adverse effects can be increased when Lacidipine is combined with Magnesium hydroxide.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Magnesium hydroxide.Approved, Investigational
LedipasvirThe serum concentration of Ledipasvir can be decreased when it is combined with Magnesium hydroxide.Approved
LercanidipineThe risk or severity of adverse effects can be increased when Lercanidipine is combined with Magnesium hydroxide.Approved, Investigational
LevofloxacinMagnesium hydroxide can cause a decrease in the absorption of Levofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
LevothyroxineThe serum concentration of Levothyroxine can be decreased when it is combined with Magnesium hydroxide.Approved
Lipoic AcidMagnesium hydroxide can cause a decrease in the absorption of Lipoic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Nutraceutical
LisdexamfetamineMagnesium hydroxide may decrease the excretion rate of Lisdexamfetamine which could result in a higher serum level.Approved, Investigational
LomefloxacinMagnesium hydroxide can cause a decrease in the absorption of Lomefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
LovastatinThe serum concentration of Lovastatin can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
Magnesium SulfateThe risk or severity of adverse effects can be increased when Magnesium Sulfate is combined with Magnesium hydroxide.Approved, Vet Approved
ManidipineThe risk or severity of adverse effects can be increased when Manidipine is combined with Magnesium hydroxide.Approved
ME-609The bioavailability of ME-609 can be decreased when combined with Magnesium hydroxide.Investigational
MecamylamineThe serum concentration of Mecamylamine can be increased when it is combined with Magnesium hydroxide.Approved
MedrysoneThe bioavailability of Medrysone can be decreased when combined with Magnesium hydroxide.Approved
MelengestrolThe bioavailability of Melengestrol can be decreased when combined with Magnesium hydroxide.Vet Approved
MemantineThe serum concentration of Memantine can be increased when it is combined with Magnesium hydroxide.Approved, Investigational
MephedroneMagnesium hydroxide may decrease the excretion rate of Mephedrone which could result in a higher serum level.Investigational
MephentermineMagnesium hydroxide may decrease the excretion rate of Mephentermine which could result in a higher serum level.Approved
MesalazineThe therapeutic efficacy of Mesalazine can be decreased when used in combination with Magnesium hydroxide.Approved
MesoridazineMagnesium hydroxide can cause a decrease in the absorption of Mesoridazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
MethamphetamineMagnesium hydroxide may decrease the excretion rate of Methamphetamine which could result in a higher serum level.Approved, Illicit
MethotrimeprazineMagnesium hydroxide can cause a decrease in the absorption of Methotrimeprazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Methylene blueMagnesium hydroxide can cause a decrease in the absorption of Methylene blue resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
MethylphenidateMagnesium hydroxide can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.Approved, Investigational
MethylprednisoloneThe bioavailability of Methylprednisolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
MetocurineMagnesium hydroxide may increase the neuromuscular blocking activities of Metocurine.Approved
Metocurine IodideMagnesium hydroxide may increase the neuromuscular blocking activities of Metocurine Iodide.Withdrawn
MevastatinThe serum concentration of Mevastatin can be decreased when it is combined with Magnesium hydroxide.Experimental
MibefradilThe risk or severity of adverse effects can be increased when Mibefradil is combined with Magnesium hydroxide.Withdrawn
MinocyclineMagnesium hydroxide can cause a decrease in the absorption of Minocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
MisoprostolThe risk or severity of adverse effects can be increased when Magnesium hydroxide is combined with Misoprostol.Approved
MivacuriumMagnesium hydroxide may increase the neuromuscular blocking activities of Mivacurium.Approved
MMDAMagnesium hydroxide may decrease the excretion rate of MMDA which could result in a higher serum level.Experimental, Illicit
MometasoneThe bioavailability of Mometasone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
MoricizineMagnesium hydroxide can cause a decrease in the absorption of Moricizine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
MoxifloxacinMagnesium hydroxide can cause a decrease in the absorption of Moxifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Investigational
Mycophenolic acidThe serum concentration of Mycophenolic acid can be decreased when it is combined with Magnesium hydroxide.Approved
NaftopidilThe risk or severity of adverse effects can be increased when Naftopidil is combined with Magnesium hydroxide.Investigational
Nalidixic AcidMagnesium hydroxide can cause a decrease in the absorption of Nalidixic Acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
NCX 1022The bioavailability of NCX 1022 can be decreased when combined with Magnesium hydroxide.Investigational
NemonoxacinMagnesium hydroxide can cause a decrease in the absorption of Nemonoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
NeosaxitoxinMagnesium hydroxide may increase the neuromuscular blocking activities of Neosaxitoxin.Investigational
NicardipineThe risk or severity of adverse effects can be increased when Nicardipine is combined with Magnesium hydroxide.Approved
NifedipineThe risk or severity of adverse effects can be increased when Nifedipine is combined with Magnesium hydroxide.Approved
NiguldipineThe risk or severity of adverse effects can be increased when Niguldipine is combined with Magnesium hydroxide.Experimental
NilotinibThe serum concentration of Nilotinib can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
NiludipineThe risk or severity of adverse effects can be increased when Niludipine is combined with Magnesium hydroxide.Experimental
NilvadipineThe risk or severity of adverse effects can be increased when Nilvadipine is combined with Magnesium hydroxide.Approved
NimesulideThe risk or severity of adverse effects can be increased when Nimesulide is combined with Magnesium hydroxide.Approved, Withdrawn
NimodipineThe risk or severity of adverse effects can be increased when Nimodipine is combined with Magnesium hydroxide.Approved
NisoldipineThe risk or severity of adverse effects can be increased when Nisoldipine is combined with Magnesium hydroxide.Approved
NitrendipineThe risk or severity of adverse effects can be increased when Nitrendipine is combined with Magnesium hydroxide.Approved
NorfloxacinMagnesium hydroxide can cause a decrease in the absorption of Norfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
OfloxacinMagnesium hydroxide can cause a decrease in the absorption of Ofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Oleoyl estroneThe bioavailability of Oleoyl estrone can be decreased when combined with Magnesium hydroxide.Investigational
OxytetracyclineMagnesium hydroxide can cause a decrease in the absorption of Oxytetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PamidronateThe serum concentration of Pamidronate can be decreased when it is combined with Magnesium hydroxide.Approved
PancuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Pancuronium.Approved
ParamethasoneThe bioavailability of Paramethasone can be decreased when combined with Magnesium hydroxide.Approved
PazopanibThe serum concentration of Pazopanib can be decreased when it is combined with Magnesium hydroxide.Approved
PazufloxacinMagnesium hydroxide can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PefloxacinMagnesium hydroxide can cause a decrease in the absorption of Pefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PenicillamineThe serum concentration of Penicillamine can be decreased when it is combined with Magnesium hydroxide.Approved
PerazineMagnesium hydroxide can cause a decrease in the absorption of Perazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PerhexilineThe risk or severity of adverse effects can be increased when Perhexiline is combined with Magnesium hydroxide.Approved
PerphenazineMagnesium hydroxide can cause a decrease in the absorption of Perphenazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PhentermineMagnesium hydroxide may decrease the excretion rate of Phentermine which could result in a higher serum level.Approved, Illicit
PinaveriumThe risk or severity of adverse effects can be increased when Pinaverium is combined with Magnesium hydroxide.Approved
PipecuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Pipecuronium.Approved
PitavastatinThe serum concentration of Pitavastatin can be decreased when it is combined with Magnesium hydroxide.Approved
Polystyrene sulfonateThe risk or severity of adverse effects can be increased when Magnesium hydroxide is combined with Polystyrene sulfonate.Approved
PrasteroneThe bioavailability of Prasterone can be decreased when combined with Magnesium hydroxide.Approved, Nutraceutical
PravastatinThe serum concentration of Pravastatin can be decreased when it is combined with Magnesium hydroxide.Approved
PrednicarbateThe bioavailability of Prednicarbate can be decreased when combined with Magnesium hydroxide.Approved
PrednisoloneThe bioavailability of Prednisolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
PrednisoneThe bioavailability of Prednisone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Magnesium hydroxide.Approved, Illicit, Investigational
PregnenoloneThe bioavailability of Pregnenolone can be decreased when combined with Magnesium hydroxide.Experimental
PrenylamineThe risk or severity of adverse effects can be increased when Prenylamine is combined with Magnesium hydroxide.Withdrawn
ProchlorperazineMagnesium hydroxide can cause a decrease in the absorption of Prochlorperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PromazineMagnesium hydroxide can cause a decrease in the absorption of Promazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
PromethazineMagnesium hydroxide can cause a decrease in the absorption of Promethazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
PropiopromazineMagnesium hydroxide can cause a decrease in the absorption of Propiopromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Vet Approved
PrulifloxacinMagnesium hydroxide can cause a decrease in the absorption of Prulifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Investigational
PseudoephedrineMagnesium hydroxide may decrease the excretion rate of Pseudoephedrine which could result in a higher serum level.Approved
PyrantelMagnesium hydroxide may increase the neuromuscular blocking activities of Pyrantel.Approved, Vet Approved
QuinidineMagnesium hydroxide may decrease the excretion rate of Quinidine which could result in a higher serum level.Approved
QuinineThe serum concentration of Quinine can be decreased when it is combined with Magnesium hydroxide.Approved
RaltegravirThe serum concentration of Raltegravir can be decreased when it is combined with Magnesium hydroxide.Approved
RapacuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Rapacuronium.Withdrawn
RilpivirineThe serum concentration of Rilpivirine can be decreased when it is combined with Magnesium hydroxide.Approved
RimexoloneThe bioavailability of Rimexolone can be decreased when combined with Magnesium hydroxide.Approved
RiociguatThe serum concentration of Riociguat can be decreased when it is combined with Magnesium hydroxide.Approved
RisedronateThe serum concentration of Risedronate can be decreased when it is combined with Magnesium hydroxide.Approved, Investigational
RitobegronMagnesium hydroxide may decrease the excretion rate of Ritobegron which could result in a higher serum level.Investigational
RocuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Rocuronium.Approved
RosoxacinMagnesium hydroxide can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
RosuvastatinThe serum concentration of Rosuvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
SimvastatinThe serum concentration of Simvastatin can be decreased when it is combined with Magnesium hydroxide.Approved
Sodium glycerophosphateThe serum concentration of Sodium glycerophosphate can be decreased when it is combined with Magnesium hydroxide.Approved
Sodium phosphatesThe serum concentration of Sodium phosphate can be decreased when it is combined with Magnesium hydroxide.Approved
SotalolThe serum concentration of Sotalol can be decreased when it is combined with Magnesium hydroxide.Approved
SparfloxacinMagnesium hydroxide can cause a decrease in the absorption of Sparfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Strontium ranelateThe serum concentration of Strontium ranelate can be decreased when it is combined with Magnesium hydroxide.Approved
SuccinylcholineMagnesium hydroxide may increase the neuromuscular blocking activities of Succinylcholine.Approved
SulpirideThe serum concentration of Sulpiride can be decreased when it is combined with Magnesium hydroxide.Approved
Technetium tc 99m etidronateThe serum concentration of Technetium tc 99m etidronate can be decreased when it is combined with Magnesium hydroxide.Approved
Technetium Tc-99m MedronateThe serum concentration of Technetium Tc-99m Medronate can be decreased when it is combined with Magnesium hydroxide.Approved
TemafloxacinMagnesium hydroxide can cause a decrease in the absorption of Temafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
TetracyclineMagnesium hydroxide can cause a decrease in the absorption of Tetracycline resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
ThiethylperazineMagnesium hydroxide can cause a decrease in the absorption of Thiethylperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Withdrawn
ThioridazineMagnesium hydroxide can cause a decrease in the absorption of Thioridazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Tiludronic acidThe serum concentration of Tiludronate can be decreased when it is combined with Magnesium hydroxide.Approved, Vet Approved
TixocortolThe bioavailability of Tixocortol can be decreased when combined with Magnesium hydroxide.Approved
Tolfenamic AcidThe risk or severity of adverse effects can be increased when Tolfenamic Acid is combined with Magnesium hydroxide.Approved
TranilastThe risk or severity of adverse effects can be increased when Tranilast is combined with Magnesium hydroxide.Approved, Investigational
TriamcinoloneThe bioavailability of Triamcinolone can be decreased when combined with Magnesium hydroxide.Approved, Vet Approved
TriethylenetetramineMagnesium hydroxide can cause a decrease in the absorption of Triethylenetetramine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
TrifluoperazineMagnesium hydroxide can cause a decrease in the absorption of Trifluoperazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
TriflupromazineMagnesium hydroxide can cause a decrease in the absorption of Triflupromazine resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Vet Approved
TrovafloxacinMagnesium hydroxide can cause a decrease in the absorption of Trovafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved, Withdrawn
TubocurarineMagnesium hydroxide may increase the neuromuscular blocking activities of Tubocurarine.Approved
VecuroniumMagnesium hydroxide may increase the neuromuscular blocking activities of Vecuronium.Approved
VerapamilThe risk or severity of adverse effects can be increased when Verapamil is combined with Magnesium hydroxide.Approved
VinpocetineThe risk or severity of adverse effects can be increased when Vinpocetine is combined with Magnesium hydroxide.Investigational
XylometazolineThe risk or severity of adverse effects can be increased when Xylometazoline is combined with Magnesium hydroxide.Approved
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Magnesium hydroxide.Approved
Zoledronic acidThe serum concentration of Zoledronic acid can be decreased when it is combined with Magnesium hydroxide.Approved
Food InteractionsNot Available
References
Synthesis ReferenceNot Available
General References
  1. Wikipedia [Link]
  2. Drugs.com [Link]
  3. Glow [Link]
  4. Medicines [Link]
  5. Drugs.com [Link]
External Links
ATC CodesA02AA04G04BX01
AHFS CodesNot Available
PDB EntriesNot Available
FDA labelNot Available
MSDSNot Available
Clinical Trials
Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedBasic ScienceHealthy Volunteers3
1CompletedTreatmentAdvanced Solid Tumors1
1CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
1, 2CompletedTreatmentChronic Kidney Disease (CKD) / Hypomagnesaemia1
2CompletedNot AvailableAcid Reflux Disease / GERD / Heartburn / Regurgitation1
3RecruitingTreatmentRadiation-induced Oesophagitis1
4CompletedTreatmentDyspepsia / Emergency / Pain1
Not AvailableCompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableCompletedPreventionPost Procedural Constipation1
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage forms
FormRouteStrength
OintmentTopical.25 %
OintmentTopical0.25 %
GelOral
Tablet, chewableOral
SuspensionOral1200 mg/15mL
SuspensionOral80 mg/mL
SolutionOral
TabletOral
LiquidOral
SuspensionOral
TabletOral385 mg
LiquidOral400 mg/5mL
EmulsionOral
ConcentrateOral2400 mg/10mL
LiquidOral400 mg
SuspensionOral2400 mg/30mL
SuspensionOral2400 mg/10mL
SuspensionOral400 mg/5mL
SuspensionOral7.75 %
LiquidOral8 g
TabletOral300 mg
SuspensionOral400 mg
SuspensionOral80 mg
SuspensionOral440 mg
Tablet, chewableOral400 mg/1
LiquidOral80 mg
Tablet, chewableOral311 mg/1
LiquidOral2400 mg/15mL
LiquidOral1200 mg/15mL
PricesNot Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5989588 Yes1998-03-302018-03-30Us
US6489346 No1996-07-162016-07-16Us
US6645988 No1996-07-162016-07-16Us
US6699885 No1996-07-162016-07-16Us
US6814978 Yes2002-02-262022-02-26Us
US7399772 No1996-07-162016-07-16Us
Properties
StateSolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
logP-0.57ChemAxon
pKa (Strongest Acidic)15.7ChemAxon
pKa (Strongest Basic)-1.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET featuresNot Available
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
Taxonomy
DescriptionThis compound belongs to the class of chemical entities known as alkaline earth metal hydroxides. These are inorganic compounds in which the largest oxoanion is hydroxide, and in which the heaviest atom not in an oxoanion is an alkaline earth metal.
KingdomChemical entities
Super ClassInorganic compounds
ClassMixed metal/non-metal compounds
Sub ClassAlkaline earth metal oxoanionic compounds
Direct ParentAlkaline earth metal hydroxides
Alternative Parents
Substituents
  • Alkaline earth metal hydroxide
  • Inorganic hydride
  • Inorganic oxide
  • Inorganic salt
Molecular FrameworkNot Available
External Descriptors
Comments
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Drug created on September 16, 2015 16:26 / Updated on March 24, 2017 04:40