Displaying drugs 201 - 225 of 3716 in total
Carisoprodol
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate ... N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Bosutinib
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea ... 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea ... 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Oxazepam
Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in...
Approved
Matched Iupac: … 7-chloro-3-hydroxy-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal ... Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal ... Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bromazepam
One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Iupac: … 7-bromo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … BROMAZANIL 3 ... LEXOTAN TABLET 3 mg ... Riva-bromazepam 3 mg …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … BROMAZANIL 3 ... LEXOTAN TABLET 3 mg ... Riva-bromazepam 3 mg …
Propranolol
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907]
Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol ... 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times …
Nitrendipine
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Proflavine
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings.
Approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Oxybenzone
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Synonyms: … Benzophenone-3 ... 2-Benzoyl-5-methoxyphenol ... 2-Hydroxy-4-methoxybenzophenone …
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Mixtures name: … Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 2) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 2) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 3) …
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Mixtures name: … Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 2) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 2) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 3) …
Diflorasone
Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
Approved
Matched Iupac: … (1R,2S,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl …
Thioridazine
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine ... 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Novo-ridazine (thioridazine Oral Suspension) - 2 mg/ml …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Novo-ridazine (thioridazine Oral Suspension) - 2 mg/ml …
Clevidipine
Clevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Approved
Investigational
Matched Iupac: … methyl 5-{[(butanoyloxy)methoxy]carbonyl}-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylate …
Donepezil
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Iupac: … 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one …
Matched Salts cas: … 120011-70-3 …
Matched Products: … DONEPEZIL HYDROCHLORIDE OD TABLETS 3 MG "MEIJI" …
Matched Salts cas: … 120011-70-3 …
Matched Products: … DONEPEZIL HYDROCHLORIDE OD TABLETS 3 MG "MEIJI" …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Influenza A virus A/Hong Kong/4801/2014 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. …
Tirofiban
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Cefaclor
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Synonyms: … 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rutin
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy ... 3-Rutinosyl quercetin ... Quercetin 3-rutinoside …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Calcium glycerophosphate
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Trimetazidine
Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260]
Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Description: … [A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Description: … It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Quazepam
Quazepam is a trifluoroethyl benzodiazepine derivative. It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABAA receptors and low affinity for...
Approved
Illicit
Matched Iupac: … 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepine-2-thione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Mixtures name: … Solcure 2 be1 Magic Pack ... Xoul Cell Illuminating 3 Step Mask ... Queen Purecell Whitening 3-step Mask …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ICEREN 2 ML 10 FLAKON ... ADENOCOR® INYECTABLE 3 MG/ML. ... ADENOSINA(SOLUCION INYECTABLE 3 MG/ML) …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Mixtures name: … Solcure 2 be1 Magic Pack ... Xoul Cell Illuminating 3 Step Mask ... Queen Purecell Whitening 3-step Mask …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ICEREN 2 ML 10 FLAKON ... ADENOCOR® INYECTABLE 3 MG/ML. ... ADENOSINA(SOLUCION INYECTABLE 3 MG/ML) …
Displaying drugs 201 - 225 of 3716 in total