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Displaying drugs 226 - 250 of 9780 in total

Exagamglogene autotemcel

Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein …

Benfotiamine

Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Approved
Experimental
Matched Categories: … Vitamin B Complex …
Matched Products: … NEVRALON B 300 MG FİLM KAPLI TABLET, 30 TABLET ... NEVRALON B 150 MG FİLM KAPLI TABLET, 30 TABLET …

Zilucoplan

Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. …
Matched Iupac: … N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-{1H-pyrrolo[2,3-b] …
Matched Description: … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein …

Niacin

Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia …
Matched Mixtures name: … Fusion Plus ... Fusion Activator Formula Tab ... Cool B …
Matched Categories: … Vitamin B Complex …
Matched Products: … B-3 500mg Continuous Released ... TABLET, 98 ADET ... TABLET, 98 ADET …

Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... , a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae* strain ... capsular antigens of *Streptococcus pneumoniae* serotype 11A individually conjugated to the CRM197 protein …

Terbutaline

Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Products: … B - LENE ... Truemed Group LLC …

Ebola Zaire vaccine (live, attenuated)

Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … (G) replaced with the Zaire Ebola Virus (ZEBOV) Kikwit 1995 strain surface glycoprotein (GP) ... Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … Ervebo consists of an envelope glycoprotein of the Zaire ebolavirus (Kikwit 1995 strain) fused into a ... [L10854] By introducing the relatively inactive viral protein to the patient, the patient’s immune system …

Brexucabtagene autoleucel

Mantle cell lymphoma is a heterogeneous sub-category of non-Hodgkin's lymphoma that can be classified as either an aggressive nodal or an indolent leukemic non-nodal variant. Despite the introduction of Bruton's tyrosine kinase (BTK) inhibitors such as ibrutinib and acalabrutinib, the prognosis for MCL patients remains poor and those that relapse...
Approved
Matched Description: … co-stimulatory domains of the chimeric antigen. ... [A216153, A216158] More recently, chimeric antigen receptor (CAR) T cell therapies have been developed ... These therapies differ in manufacturing methodology, viral vector, chimeric antigen choice, and the internal …
Matched Categories: … Membrane Proteins ... Receptors, Antigen ... Receptors, Antigen, T-Cell …

Lomefloxacin

Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational

Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen

Approved
Investigational
Matched Name: … Human papillomavirus type 18 L1 capsid protein residues 2-472 antigen …

Ropivacaine

Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Products: … ROPIVACAINA B. BRAUN ... Ropivacain-HCl B. Braun 5 mg/ml Injektionslösung ... Ropivacain-HCl B. Braun 10 mg/ml Injektionslösung …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton …
Matched Categories: … Membrane Proteins …
Matched Products: … Truemed Group LLC …

Ginkgo biloba

Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Description: … _Ginkgo biloba_ extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ... Lactones include ginkgolide A, ginkgolide B, ginkgolide C, bilobalide, and ginkgotoxin, a lactone that …
Matched Products: … TEBONIN 120MG B OHRGERAEU …

Luspatercept

Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Description: … Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin …
Matched Categories: … Membrane Proteins ... Phosphotransferases (Alcohol Group Acceptor) ... Protein Kinases ... Protein-Serine-Threonine Kinases …

Beroctocog alfa

Approved
Investigational
Matched Categories: … Protein Precursors …
Matched Products: … Truemed Group LLC …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … A31311] It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion …
Matched Categories: … Protein Kinase Inhibitors …

Budesonide

Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Categories: … Corticosteroids, Potent (Group III) …
Matched Products: … DANKIAL-B ... B-CORT ® 50 ... B-CORTUNGÛENTO …

Imiquimod

Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Truemed Group LLC …

Lomitapide

Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Description: … Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial …
Matched Categories: … Microsomal Triglyceride Transfer Protein Inhibitor ... Microsomal Triglyceride Transfer Protein Inhibitors …

Trovafloxacin

Trovafloxacin is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. It exerts its antibacterial activity by inhibiting the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV. It was shown to be more effective...
Approved
Investigational
Withdrawn

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …

Amikacin

Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group …
Matched Products: … AMIKACINA B. BRAUN ... Amikacin B. Braun 5 mg/ml Infusionslösung ... Amikacin B. Braun 2,5 mg/ml Infusionslösung …

Pefloxacin

A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.
Approved

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Products: … Truemed Group LLC …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Mixtures name: … Eucillin "B" - Salbe ... BACITRACIN - POLYMYXIN B ... Bacitracin Zinc and Polymyxin B Sulfate …
Displaying drugs 226 - 250 of 9780 in total