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Displaying drugs 251 - 275 of 332 in total

Ranolazine

Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Iupac: … N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide …
Matched Salts cas: … 95635-56-6 …
Matched Categories: … MATE 2 Inhibitors ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... P-glycoprotein inhibitors ... P-glycoprotein substrates …

Dasiglucagon

Dasiglucagon is a glucagon analog that acts to increase blood sugar levels. It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and chemical stability in its drug formulation. In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia...
Approved
Investigational
Matched Description: … annually, about 7% to 25% of patients with type 2 diabetes mellitus treated with insulin experience ... Although it tends to be more common in type 1 diabetes mellitus, occurring in about 22% to 46% of patients ... amino acids for improved physical and chemical stability in its drug formulation. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Iupac: … -undecaazacyclooctatriacontane-4-carboxylic acid ... ]acetamido}-13,25,28-tribenzyl-31-(carbamoylmethyl)-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)- ... (4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-37-{2-[(2S)-2-aminopropanamido ... 22-[(1H-indol-3-yl)methyl]-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35 …
Matched Description: … Somatostatin is initially secreted as a 116 amino acid precursor, preprosomatostatin, which undergoes ... acid residues [T28] that regulates the endocrine system. ... also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino …
Matched Salts cas: … 54472-66-1 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... P-glycoprotein substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …
Matched Products: … SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPUL ... SOMATEX 3 MG I.V. İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ AMPUL ... Somatostatin "Eumedica" 6 mg - Pulver und Lösungsmittel zur Herstellung einer Infusionslösung …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Iupac: … N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-{2-[(propan-2-yl)amino]ethyl}quinoxalin-6-amine …
Matched Categories: … P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … BALVERSA 5 MG FİLM KAPLI TABLET, 28 ADET ... BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADET ... BALVERSA 3 MG FİLM KAPLI TABLET, 84 ADET …

Pantoprazole

Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Iupac: … 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Pantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid ... This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid …
Matched Salts cas: … 199387-73-0 ... 164579-32-2 …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... P-glycoprotein inhibitors …
Matched Products: … Pantoprazole Sodium D/r ... Rixubis 1000 IU/5 ml IV Enjeksiyonluk Çözelti Hazırlamak İçin Liyofilize Toz ve Çözücü, 1 adet toz içeren ... GASPAZOL 40 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 5 FLAKON …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … D-5-1/3 S ... D-5-1/2S ... Lactate 1-2-3 Injection …
Matched Products: … Dextrose Inj 5% ... GLUCOSIO 5% BAXTER ... 5% Dextrose Injection USP …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Iupac: … 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide …
Matched Mixtures name: … PERDAPAX 2 MG/0.625 MG TABLET, 30 ADET ... ACEPER PLUS 2 MG/0.625 MG TABLET, 30 ADET ... PADERO PLUS 2 MG/0,625 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Non Potassium Sparing Diuretics ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …

Salmon calcitonin

Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … MIACALCIC 100 IU AMPUL, 5 ADET …

Zinc sulfate

Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Iupac: … zinc(2+) sulfate …
Matched Salts cas: … 7446-20-0 ... 7446-19-7 …
Matched Mixtures name: … Visine for Allergy 3 Symptom Relief ... Clear Eyes Complete 7 Sympton Relief ... Multitrace-5 …
Matched Products: … R-ZINC ... FORTZINK JARABE 20 MG/5 ML ... CHINKO 15 MG/5 ML SURUP, 100 ML …

Magnesium carbonate

Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Approved
Investigational
Matched Iupac: … magnesium(2+) carbonate …
Matched Description: … magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid …
Matched Salts cas: … 39409-82-0 …
Matched Mixtures name: … Mag/cal 1:1 Capsules W Vitamin D ... NEUTROSE S. PELLEGRINO ... NEUTROSE S. PELLEGRINO …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Iupac: … (1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-1-(2-chloroacetyl)-9b-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, ... 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. ... Ciclopirox 1% / Clobetasol Propionate 0.05% …
Matched Categories: … Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A5 Inducers …
Matched Products: … STERIDERM-S CREAM 0.05% ... PROCORT(R) LOCIÓN CAPILAR …

Zinc chloride

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Iupac: … zinc(2+) dichloride …
Matched Mixtures name: … AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML ... AMINOMIX 3 SOLÜSYON, 15000 ML …
Matched Products: … Perioselect Zinc Chloride Solution 1% …

Pectin

Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... -4. …
Matched Mixtures name: … LEOLIN-P® ... KAOMYCIN S SIMPLE …

Desvenlafaxine

Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched Iupac: … 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol …
Matched Description: … Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine]. …
Matched Salts cas: … 93414-04-1 ... 300827-87-6 ... 386750-22-7 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 CYP2C19 Substrates …

Methazolamide

A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Iupac: … N-[(2E)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Butamben

Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben is considered to be suitable only for...
Approved
Withdrawn
Matched Iupac: … butyl 4-aminobenzoate …
Matched Description: … Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. …
Matched Salts cas: … 577-48-0 …
Matched Categories: … Carboxylic Acids …

Prussian blue

Prussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs. It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure. It is insoluble in water but also tends to form a colloid thus can exist in either colloidal or water-soluble...
Approved
Matched Iupac: … tetrairon(3+) ion tris(hexacyanoirontetrauide) …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Iupac: … (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl ... ]methyl}-8-methyl-2-(propan-2-yl)nonanamide …
Matched Salts cas: … 173334-58-2 …
Matched Categories: … Carboxylic Acids ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …

Clofazimine

Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin...
Approved
Investigational
Matched Iupac: … N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP3A Inhibitors …

Ancrod

Ancrod, marketed as Viprinex, is a defibrinogenating agent derived from Malayan pit viper venom. The defribrinogenation of blood results in an anticoagulant effect. Currently, Viprinex®/ancrod is not approved or marketed in any country, but is being investigated as a stroke treatment in worldwide clinical trials. In January 2005, the U.S....
Approved
Investigational

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Iupac: … -2-carboxylic acid ... (2S,4S)-4-cyclohexyl-1-(2-{[(1S)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine …
Matched Description: … Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme …
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Peptides, and Proteins …

Oliceridine

Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors.[A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible for...
Approved
Investigational
Matched Iupac: … [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl]ethyl})amine …
Matched Description: … [A218041] Oliceridine gained FDA approval on August 7, 2020, and is currently marketed by Trevena Inc …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP3A Substrates …

Potassium phosphate, dibasic, trihydrate

Experimental
Matched Synonyms: … Dipotassium monophosphate trihydrate ... Dipotassium hydrogen phosphate trihydrate …
Matched Name: … Potassium phosphate, dibasic, trihydrate …
Matched Iupac: … dipotassium trihydrate hydrogen phosphate …

Potassium bitartrate

Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Synonyms: … Potassium bitartrate ... potassium hydrogen tartrate …
Matched Name: … Potassium bitartrate …
Matched Iupac: … potassium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate …
Matched Description: … Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium ... acid salt of l-( + )-tartaric acid. ... Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer …
Matched Categories: … Potassium Salt …

Potassium iodate

Experimental
Matched Synonyms: … Iodic acid, potassium salt …
Matched Name: … Potassium iodate …
Matched Iupac: … potassium iodate …
Displaying drugs 251 - 275 of 332 in total