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Displaying drugs 26 - 50 of 106 in total
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. ... is not tumour-specific and can also be found in normal B-cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … B-cells that express the CD20 antigen. ... [L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets ... leads to neurological disabilities and a significantly reduced quality of life. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice. It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that...
Approved
Investigational
Matched Description: … [A187349] It was generated via recombinant human IL-12 immunization of human Ig (hu-Ig) transgenic mice ... Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin( ... [A187349] It is a targeted biologic disease-modifying anti-rheumatic drug (bDMARDs) that is used in the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell...
Approved
Investigational
Matched Description: … A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive ... as CD25 antigen) on the surface of activated T-lymphocytes. ... agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B surface antigen (recombinant) ... Hepatitis B antigen ... Hepatitis B surface antigen
Matched Name: … Hepatitis B Vaccine (Recombinant) …
Matched Description: … This resulted from a significant decline in the prevalence of hepatitis B antigen, the persistence of ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. ... It is estimated that the reservoir of persistent hepatitis B surface antigen carriers amounts to 350 …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen
Matched Categories: … haemophilus influenzae B and hepatitis B ... Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... Hepatitis B Antigens ... Hepatitis B Vaccines …
Matched Products: … Engerix-B ... Heplisav-B ... ENGERIX-B
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Synonyms: … Lipoprotein OspA antigen recombinant ... Lipoprotein outer surface a borrelia burgdorferi antigen
Matched Name: … Lyme disease vaccine (recombinant OspA) …
Matched Description: … Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the …
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant NADA fusion protein antigen
Matched Name: … Neisseria meningitidis serogroup b nada protein antigen
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen
Matched Name: … Neisseria meningitidis serogroup b nhba fusion protein antigen
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Synonyms: … Recombinant varicella zoster virus glycoprotein E antigen ... gE recombinant Varicella zoster virus (VZV) glycoprotein E ... Recombinant Varicella zoster virus (VZV) glycoprotein E …
Matched Name: … Varicella zoster vaccine (recombinant) …
Matched Description: … non-live recombinant vaccine indicated for prevention of shingles. ... Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted ... Following initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Washington/02/2019 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
Matched Categories: … Recombinant influenza vaccines …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Maryland/15/2016 recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Brisbane/02/2018 (H1N1) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Minnesota/41/2019 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/West Virginia/30/2022 (H1N1) Recombinant Hemagglutinin Antigen
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Recombinant influenza vaccines …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen
Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. It is intended to elicit protection against Omicron XBB.1.5, one of the dominant circulating SARS-CoV-2 subvariants in 2023. It is produced using recombinant DNA technology in CHO cell lines and...
Approved
Matched Synonyms: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351 ... -B.1.1.7 strains …
Matched Name: … SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351 ... -B.1.1.7 strains) …
Matched Description: … [A262551] It is produced using recombinant DNA technology in CHO cell lines and is marketed by Hipra ... Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein ... [L48902,L48907] Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster …
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 58 L1 protein …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 58 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 11 L1 protein …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza B virus B/Austria/1359417/2021 BVR-26 antigen (UV, formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza B Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A Virus A/California/122/2022 SAN-022 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et al., PNAS 100:12590, 2003)....
Approved
Investigational
Matched Synonyms: … Recombinant soluble prostate-specific membrane antigen (rsPSMA) vaccine …
Matched Description: … and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA ... Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular ... Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly …
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Synonyms: … Abatacept recombinant
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. ... It is produced through recombinant DNA technology in mammalian CHO cells. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 26 - 50 of 106 in total