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Displaying drugs 501 - 525 of 602 in total

Beraprost

Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.
Investigational
Matched Salts name: … Beraprost sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … BERAPROST SODIUM …

ENB-003

ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.
Investigational
Matched Synonyms: … sodium bispiperidine-carboxamido-dimethylpenatnamido-methoxycarbonyl-indol-propanamidohexanoate …
Matched Description: … ENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for …

Cilastatin

Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Mixtures name: … IMIPEMEM CILASTATINA SODICA ... IMIPENEM MONOHYDRATE - CILASTATIN SODIUM ... IMIPENEM MONOHYDRATE / CILASTATIN SODIUM …
Matched Salts name: … Cilastatin sodium …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Matched Products: … Cilastatin Sodium Sterile …

Fondaparinux

Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they ... The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural …
Matched Salts name: … Fondaparinux sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Fondaparinux Sodium ... FONDAPARINUX SODIUM ... Fondaparinux Sodium Injection …

Nedocromil

A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Description: … are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and …
Matched Salts name: … Nedocromil sodium …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Nedocromil Sodium …

Butyric Acid

A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
Experimental
Investigational
Matched Description: … A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the …
Matched Salts name: … Sodium butyrate …
Matched Products: … Sodium Butyrate …

Sulbenicillin

Experimental
Matched Salts name: … Sulbenicillin sodium …
Matched Products: … SULBENICILLIN SODIUM …

Pegylated Recombinant Human Arginase I

Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Investigational
Matched Synonyms: … Pegylated recombinant human arginase i bct-100 …
Matched Name: … Pegylated Recombinant Human Arginase I …
Matched Description: … Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)). ... Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …

N,N-dimethylarginine

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a...
Experimental
Matched Synonyms: … dimethyl-L-arginine ... NG,NG-Dimethyl-L-arginine …
Matched Description: … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and ... continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Enoxaparin

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients...
Approved
Matched Description: … Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various ... Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and …
Matched Mixtures name: … ENOXAPARINA SODICA 40 MG JERINGAS PRELLENADAS …
Matched Salts name: … Enoxaparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … Enoxaparin Sodium ... Enoxaparin sodium ... EXIRINA® ENOXAPARINA SODICA 20 MG/0.2 ML …

Hydroxyethyl Starch

Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Approved
Matched Description: … , concentration, C2/C6 ratio and Maximum Daily Dose. ... HES is a general term and can be sub-classified according to average molecular weight, molar substitution …
Matched Mixtures name: … Hydroxyethyl Starch in Sodium Chloride ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLİ ... NEOHES %6 HES % 0.9 SODYUM KLORÜR İV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSİZ …
Matched Categories: … Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … Hetastarch in Sodium Chloride ... 6% Hetastarch In 0.9% Sodium Chloride …

Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Salts name: … Ceftriaxone sodium …
Matched Products: … Ceftriaxone and Dextrose ... Ceftriaxone Sodium ... CEFTRIAXONE SODIUM …

Phenylbutyric acid

Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Description: … It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Salts name: … Sodium phenylbutyrate …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... sodium phenylbutyrate …
Matched Products: … Sodium Phenylbutyrate …

Tolmetin

A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Salts name: … Tolmetin sodium …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Tolmetin Sodium …

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Salts name: … Cloxacillin sodium ... Cloxacillin sodium hydrate …
Matched Products: … CLOXACILLINA SODICA ... Cloxacillin Sodium for Injection ... Cloxacillin Sodium Sterile Inj 250mg/vial …

Foscarnet

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Salts name: … Foscarnet sodium …
Matched Products: … Foscarnet Sodium …

Dinor-N(Omega)-Hydroxy-L-Arginine

Experimental
Matched Name: … Dinor-N(Omega)-Hydroxy-L-Arginine …

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and ... to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and …
Matched Mixtures name: … Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide …
Matched Salts name: … Fosinopril sodium …
Matched Categories: … ACE Inhibitors and Diuretics ... fosinopril and diuretics ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fosinopril Sodium ... Fosinopril sodium …

Tozuleristide

Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … (K>R),23-ARGININE(K>R))CHLOROTOXIN (CTX, CLTX) LEIURUS QUINQUESTRIATUS QUINQUESTRI ... INDOL-1-IUM-2-YL)HEPTA-2,4,6-TRIENYLIDENE)-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium …
Matched Salts name: … Ampicillin sodium …
Matched Products: … Ampicillin Sodium ... AMPICILLIN SODIUM ... AMPICILLINA SODICA …

Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts name: … Bromfenac sodium …
Matched Products: … Bromfenac Sodium …

Sulfadiazine

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and …
Matched Salts name: … Sulfadiazine sodium …
Matched Categories: … sulfadiazine and tetroxoprim ... Sulfonamides and trimethoprim ... sulfadiazine and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sulfadiazine Sodium …

Edetate calcium disodium anhydrous

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Calcium Edetate de Sodium …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Salts name: … Methylprednisolone sodium succinate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Methylprednisolone Sodium Succinate ... METHYLPREDNISOLONE SODIUM SUCCINATE ... Methylprednisolone sodium succinate …
Displaying drugs 501 - 525 of 602 in total