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Displaying drugs 526 - 550 of 648 in total
Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide. The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly releases N-acetyl-gamma-calicheamicin dimethylhydrazide, which produces cytotoxic effects. Inotuzumab ozogamicin was first...
Approved
Investigational
Matched Description: … [A20352] The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BESPONSA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1MG/VIAL …
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … HYCAMTIN (POWDER FOR SOLUTION FOR INFUSION) ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4MG ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4 MG/VIAL …
Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ONCASPAR POWDER FOR SOLUTION FOR INJECTION/INFUSION 750 U/ML …
Experimental
Matched Products: … LACTOMEDI Ferminine Probiotics Powder Mist …
A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched Synonyms: … Iron powder
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms …
Matched Mixtures name: … Multi Vitamin, Iron and Fluoride ... Multi-Vitamin Fluoride and Iron Drops ... Children's Chewable Vit and Min Tab …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... multivitamins and iron ... iron and multivitamins ... Blood and Blood Forming Organs …
Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile . It is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis. Invasive fungal infections pose significant clinical challenges for patients, especially those...
Approved
Investigational
Matched Description: … It is approved by the FDA and EMA for the treatment of invasive aspergillosis and mucormycosis. ... The prodrug formulation of isavuconazole is FDA- and EMA-approved and is marketed under the trade name ... Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile [A32026 …
Matched Categories: … Isavuconazole and Prodrugs ... Triazole and tetrazole derivatives …
Matched Products: … CRESEMBA (POWDER FOR SOLUTION FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200 MG/VIAL) …
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Matched Description: … A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … GLIOLAN, POWDER FOR ORAL SOLUTION, 30 MG/ML …
Black cohosh (Actaea racemosa or Cimicifuga racemosa), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism weed. Black cohosh has a long history of use. Native Americans used it for its...
Experimental
Matched Description: … mood disturbance, and hot flushes. ... Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheumatism ... for its purported benefits in treating musculoskeletal pain, fever, cough, pneumonia, sluggish labor, and
Matched Categories: … Herbs and Natural Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Black Cohosh Root Powder
Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Description: … promotes tumor cell lysis and apoptosis. ... monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and ... blinatumomab has an affinity to both antigens, it redirects T-cells to tumor cells expressing CD19 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL …
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Products: … Desferal 500mg Powder for Solution for Injection …
Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Description: … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and ... Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July ... 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed …
Matched Categories: … Isavuconazole and Prodrugs …
Matched Products: … CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MG …
Investigational
Matched Synonyms: … cell costimulator ligand variant immunoglobulin domain designed to inhibit simultaneously the CD28 and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Approved
Matched Products: … TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vial …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … kidneys and the inner ear. ... an oral liquid formulation is expected to make _Clostridium difficile_ associated diarrhea therapy more ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … VANCONEX LYOPHILIZED POWDER FOR INJECTION 1G/VIAL ... VANCONEX LYOPHILIZED POWDER FOR INJECTION 500MG/VIAL ... CELOVAN Powder for Solution for Injection/Infusion 500 mg …
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PROLEUKIN POWDER FOR INFUSION 18 miu/vial …
Tribulus terrestris root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Tribulus Terrestris Root Powder
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … ) and is generally more effective and more tolerable than [linezolid]. ... This product is currently available as both an oral tablet and as a powder for intravenous injection. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and
Matched Products: … SIVEXTRO LYOPHILIZED POWDER FOR SOLUTION FOR INFUSION 200MG PER VIAL …
Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vial …
Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Categories: … Enzymes and Coenzymes …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …
Acorus calamus root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Acorus Calamus Powder ... Acorus Calamus Root Powder
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Synonyms: … Aloe vera leaf powder ... Aloe barbadensis leaf powder ... Aloe barbadensis leaf juice powder
Matched Description: … genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and ... or _Aloe barbadensis miller_, is the most common species of Aloe that is cultivated for agricultural and ... While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and
Matched Mixtures name: … Mousturizing Gloves and Socks ... Hair Volume Powder
Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Melia Azadirachta Leaf Powder
Pecan allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Carya illinoinensis seed
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Categories: … Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Thymoglobuline 5mg/ml Powder for concentrate for solution for infusion …
Displaying drugs 526 - 550 of 648 in total