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Displaying drugs 526 - 550 of 760 in total
Investigational
Matched Synonyms: … -lactone
Matched Categories: … Indicators and Reagents …
Experimental
Matched Name: … Rose bengal lactone
Experimental
Matched Name: … 3'-beta-Sialyl-beta-lactose
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Description: … ), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … VISTAGAN LIQUIFILM 0.5%O K
Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Description: … Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms ... that include anorexia, nausea, vomiting, and liver failure. ... [A199182] Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been …
Matched Products: … VAQTA K pro infantibus 25 E/0,5 ml Injektionssuspension ... VAQTA K pro infantibus 25 E/0,5 ml Injektionssuspension in einer Fertigspritze …
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched International brands: … Vepesid K
Matched Description: … Etoposide acts primarily in the G2 and S phases of the cell cycle. ... Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … SINTOPOZID 100 MG/5 ML IV KON. INFUZYON COZELTISI ICEREN FLAKON, 1 ADET …
Tozuleristide is under investigation in clinical trial NCT02464332 (Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery).
Investigational
Matched Synonyms: … R),23-ARGININE(K>R))CHLOROTOXIN (CTX, CLTX) LEIURUS QUINQUESTRIATUS QUINQUESTRI ... 2-YL)HEPTA-2,4,6-TRIENYLIDENE)-1,1-DIMETHYL-1,2-DIHYDRO-3H-BENZO(E)INDOL-3-YL)HEXANOYL)(15-ARGININE(K> …
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Synonyms: … Glycyl-prolyl-glutamic acid …
Matched Description: … Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Pyridone 6 …
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … and reducing cough. ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Categories: … Cough and Cold Preparations …
Matched Products: … BROMHEXIN K M TABL 12MG ... BROMHEXIN K M TRF 8MG/ML ... BROMHEXIN K M TRF 12MG/ML …
Experimental
Matched Name: … 3-(INDOL-3-YL) LACTATE
Hydronidone has antifibrotic activity.
Investigational
Matched Synonyms: … N-(4-Hydroxyphenyl)-5-methyl-2-pyridone
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … -lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Pyridine-2-thiol …
Matched Iupac: … pyridine-2-thiol …
Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a mast cell stabilizer. Thus it is used in allergic conditions such as allergic conjunctivitis. Specifically spaglumic acid is approved...
Experimental
Matched Synonyms: … N-Acetyl-L-β-aspartyl-L-glutamic acid …
Matched Description: … Specifically spaglumic acid is approved in Portugal under the brand name Naabak and in Greece under the ... β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic
Matched Categories: … Decongestants and Antiallergics …
Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products . Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Synonyms: … Lactated pepsin …
Matched Description: … Stimulation of the pancreas and therefore enzymatic digestion of food is a tightly controlled and is ... Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and ... Any changes or conditions affecting metabolic steps for successful digestion and absorption negatively …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Betaine HCl and Pepsin ... Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... pepsin and acid preparations …
Experimental
Matched Name: … N-Acetyl-L-Glutamate
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Glutamate carboxypeptidase …
Matched Description: … [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin ... This can lead to delayed renal clearance of methotrexate and elevated drug plasma levels, increasing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … 3-(Methylcarbamoyl)pyridine ... 3-(N-Methylcarbamoyl)pyridine
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I. …
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Synonyms: … Special K
Matched Description: … it produced minor hallucinogenic effects and shorter psychotomimetic effects. ... It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, ... It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … KTM - 100 …
Mometasone is a corticosteroid not currently used in medical products. Mometasone furoate however, is still in use.
Experimental
Matched Categories: … indacaterol and mometasone ... indacaterol, glycopyrronium bromide and mometasone …
Matched Products: … K-ALLEXIN %0,05 NAZAL SPREY 18 G 140 DOZ …
Experimental
Matched Name: … 3-(Mercaptomethylene)Pyridine
Experimental
Matched Name: … Xylose-derived lactam oxime …
Displaying drugs 526 - 550 of 760 in total