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Displaying drugs 76 - 100 of 1414 in total
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... ciprofloxacin and tinidazole …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% ... CIROK INJECTION 2 mg/ml …
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched International brands: … Lidoject-1 ... Lidoject-2
Matched Synonyms: … 2-(Diethylamino)-2',6'-acetoxylidide ... 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Iupac: … 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide …
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and
Matched Mixtures name: … Lidocaine 2% and Epinephrine 1:50,000 ... Lidocaine 2% and Epinephrine 1:50 000 ... Lidocaine 2% and Epinephrine 1:50,000 …
Matched Categories: … Analgesics and Anesthetics ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Foster and Thrive ... Soulus Rp Rash and Pain ... Terrasil Rash and Pain Relief …
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto ... Ethyl N-[(3R,3aS,4S,4aR,7R,8aR,9aR)-4-[(E)-2-[5-(3-fluorophenyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a ... -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 1-Ring ... Protease-activated Receptor-1 Antagonist ... Protease-activated Receptor-1 Antagonists ... Receptor, PAR-1, antagonists & inhibitors …
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used ... [A248440] Mavacamten was also approved by Health Canada in October 2022 and by EMA in July 2023 for the …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene ... DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R …
Matched Description: … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid ... N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2'-Deoxy-5-ethyluridine ... 5-Ethyl-2'-deoxyuridine …
Matched Iupac: … 5-ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. ... [A32643] It was developed by McNeil Pharmaceutical and approved by Health Canada on December 31, 1992 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Nucleic Acids, Nucleotides, and Nucleosides …
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Synonyms: … isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinate …
Matched Iupac: … propan-2-yl 2-({6-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]pyridin-2-yl}amino …
Matched Description: … topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ... isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and ... [A253253] In 2018, omidenepag isopropyl was approved in Japan for the treatment of glaucoma and ocular …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … COP 1 ... COP-1 ... Copolymer-1
Matched Description: … [A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate ... L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2 ... 17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan ... 21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine …
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 …
Matched Description: … Buprenorphine is commercially available as the brand name product Suboxone which is formulated in a 4:1 ... who require larger and more frequent doses. ... an improved safety profile with a lower risk of overdose and respiratory depression. …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten ... Suboxone 8 mg/2 mg sublingual tablets ... Suboxone 2 mg/0.5 mg sublingual tablets …
Matched Products: … Bupensan 1 mg-Sublingualtabletten ... BUPENSAN 2 MG ... BUPRENORPHIN-NEURAX 2 MG …
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester ... (±)-2-methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate ... 2-methyl-2-propyltrimethylene carbamate isopropylcarbamate …
Matched Iupac: … 2-[(carbamoyloxy)methyl]-2-methylpentyl N-(propan-2-yl)carbamate …
Matched Description: … acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and ... itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and
Matched Mixtures name: … Carisoprodol and Aspirin ... Carisoprodol and Aspirin ... Carisoprodol and Aspirin …
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal …
Matched Salts cas: … 122852-69-1
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is...
Approved
Matched Synonyms: … Copper(2+) sulfate ... Copper sulfate (1:1) …
Matched Iupac: … copper(2+) sulfate …
Matched Description: … After zinc and iron, copper is the third most abundant trace element found in the human body. ... The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary ... Copper is an essential trace element and an important catalyst for heme synthesis and iron absorption …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Efferlife Multivitamins and Minerals ... Multiple Vitamins and Minerals Capsules …
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid ... 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] …
Matched Iupac: … }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid ... 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl …
Matched Description: … and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and ... is used in the treatment of impetigo caused by _Staphylococcus aureus_ and _Streptococcus pyogenes_ …
Matched Mixtures name: … Pre and Post Sx Pouch ... Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine ... N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor ... [L46018] Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Synonyms: … Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate …
Matched Iupac: … hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate …
Matched Description: … Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic ... U.S., South America, Mexico, Japan and Taiwan. ... Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …
Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Synonyms: … ),5'-(P-(4-((2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)carbonyl)-1-piperazinyl)-N,N-dimethylphosphonamidate ... (P-deoxy-P-(dimethylamino)](2',3'-dideoxy-2',3'-imino-2',3'-seco)(2'a→5')(C-m5U-C-C-A-A-C-A-m5U-C-A-A-G-G-A-A-G-A-m5U-G-G-C-A-m5U-m5U-m5U-C-m5U-A-G …
Matched Description: … Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. ... a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and ... Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Nucleic Acids, Nucleotides, and Nucleosides …
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Synonyms: … 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... other allergens, and to prolong the action of infiltration anesthetics [F2136]. ... Many new products/biosimilars and dosage routes have been approved under various names over the last …
Matched Salts cas: … 55-31-2
Matched Mixtures name: … Lidocaine 2% and Epinephrine 1:50,000 ... Lidocaine 2% and Epinephrine 1:50 000 ... Lidocaine 2% and Epinephrine 1:50,000 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists ... Epinephrine and similars …
Matched Products: … Gingi-pak Max 2-ply ... Gingi-pak Max Z-twist No 2 ... Gingi-pak Max Soft-twist No 2
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Matched Products: … VEGIRO 100 MG FILM TABLET,1 ADET ... DEGRA 50 MG FILM KAPLI TABLET, 1 ADET ... DEGRA 100 MG FILM KAPLI TABLET, 1 ADET …
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Synonyms: … (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide …
Matched Iupac: … 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide …
Matched Description: … [Label] Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely ... in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Selective Alfa-1-adrenergic Blocking Agents ... tamsulosin and tadalafil ... tamsulosin and dutasteride …
Matched Products: … TAMSULOSINA FARMA 1
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid …
Matched Iupac: … 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6,2-benzothiazine-3-carboxamide …
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … STOPEN GEL 1% ... PIROXICAM GEL 1% ... PIROXICAM INYECCION 40 MG /2 ML …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid …
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid …
Matched Description: … [L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, ... and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … Allergy and Congestion ... Allergy and Congestion ... Allegra-D Allergy and Congestion …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … MATE 2-K Inhibitors ... Antineoplastic and Immunomodulating Agents ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … .DELTA.1-THC ... delta(1)-tetrahydrocannabinol ... 1-trans-delta-9-Tetrahydrocannabinol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid ... -2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite ... , reduced pain, and changes in emotional and cognitive processes. …
Matched Categories: … Cannabinoids and similars ... Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine is commonly used in the treatment of high blood pressure and angina. ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and
Matched Salts cas: … 652969-01-2
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... losartan and amlodipine ... ramipril and amlodipine ... nebivolol and amlodipine ... aliskiren and amlodipine …
Matched Products: … PRESONE-1
Displaying drugs 76 - 100 of 1414 in total