Displaying drugs 1051 - 1075 of 1094 in total
Cinrebafusp alfa
Investigational
Matched Synonyms: … PEPTIDE (SYNTHETIC 15-AMINO ACID LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU ... S228>P,F234>A,L235>A) IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN ... (HUMAN TYROSINE KINASE RECEPTOR HER2) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN …
Talditercept alfa
Talditercept alfa is under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and Tolerability of RO7239361 in Ambulatory Boys With Duchenne Muscular Dystrophy).
Investigational
Matched Synonyms: … Immunoglobulin g1 (human fc fragment) fusion protein with peptide (synthetic 17-amino acid linker) fusion ... protein with adnectin, anti-(human growth differentiation factor 8) (human clone bms-986089 fibronectin …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Matched Description: … under investigation in clinical trial NCT03039686 (Clinical Trial to Evaluate the Efficacy, Safety, and …
Ezabenlimab
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Matched Description: … It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgfbeta receptor ectodomain-igg fc fusion protein avid200 …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Retlirafusp alfa
Investigational
Matched Synonyms: … with peptide linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. ... anti-(human programmed death-ligand 1) (human-mus musculus monoclonal SHR-1316 .gamma.4-chain) fusion protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Proteins …
Dapirolizumab pegol
Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … tumor necrosis factor ligand superfamily member 5, tnfsf5, tumor necrosis factor related activation protein …
Matched Description: … Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Description: … Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Folic acid
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … methionine before incorporation into DNA or protein. ... cofactor for enzymes involved in DNA and RNA synthesis. ... Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential …
Matched Mixtures name: … Luna Vitamin and Mineral Bar for Women ... Reliv So Sense Daily Vitamin Supplement ... Fem - Protect …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... iron, multivitamins and folic acid ... ferrous sulfate and folic acid …
Matched Products: … LIVY´S GOVELCA ACIDO FOLICO …
Matched Mixtures name: … Luna Vitamin and Mineral Bar for Women ... Reliv So Sense Daily Vitamin Supplement ... Fem - Protect …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... iron, multivitamins and folic acid ... ferrous sulfate and folic acid …
Matched Products: … LIVY´S GOVELCA ACIDO FOLICO …
Quisovalimab
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins …
Human C1-esterase inhibitor
C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways.[L16586, L16606]
This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a...
Approved
Matched Synonyms: … Plasma protease C1 inhibitor …
Matched Description: … The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE ... The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Proteins ... Blood Proteins ... Protease Inhibitors …
Matched Description: … The primary function of endogenous C1INH is to regulate the activation of the complement and contact ... [L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE ... The disease is characterized by acute attacks of painful, and in some cases, fatal swelling of several …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Proteins ... Blood Proteins ... Protease Inhibitors …
Yohimbine
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched International brands: … Baron-X …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Genito Urinary System and Sex Hormones …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein …
Matched Description: … cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation …
Matched Description: … cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation …
Reveglucosidase alfa
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE]AMINO}UNDECAN-2-ONE
Experimental
Matched Name: … 1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE …
Norfloxacin
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Description: … fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and …
Matched Categories: … norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SENRO ® …
Matched Categories: … norfloxacin and tinidazole ... norfloxacin and metronidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SENRO ® …
Betahistine
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408]
Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Products: … BEENA …
Matched Products: … BEENA …
Hepatitis B Vaccine (Recombinant)
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada.
The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B virus hbsag surface protein antigen …
Matched Description: … Carriers are at a high risk of developing chronic liver disease which may lead to cirrhosis or primary ... lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B ... Proteins ... Viral Proteins …
Matched Description: … Carriers are at a high risk of developing chronic liver disease which may lead to cirrhosis or primary ... lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B ... Proteins ... Viral Proteins …
Ifinatamab deruxtecan
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA …
Depelestat
Investigational
Matched Synonyms: … kunitz domain of inter-alpha-trypsin inhibitor light chain: (glu285,ile297,phe300,pro301,arg302)ambp protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hydromorphone
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and ... Due to these modifications, it presents a very high potency and comparable side effect profile to the …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Bar-hydromorphone CR …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Bar-hydromorphone CR …
Rivabazumab pegol
Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN FAB' G1-KAPPA PEGYLATED, ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … opioids and who require larger and more frequent doses. ... reducing the reinforcing effects of opioids which can lead to drug-seeking behaviours. ... Use of once-daily buprenorphine may benefit individuals who have developed tolerance to other potent …
Matched Mixtures name: … Buprenorphine HCl and Naloxone HCl ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … Bar-buprenorphine …
Matched Mixtures name: … Buprenorphine HCl and Naloxone HCl ... Buprenorphine and Naloxone ... Buprenorphine and Naloxone …
Matched Products: … Bar-buprenorphine …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and ... the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and ... Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Protein Synthesis Inhibitors …
Matched Products: … Spotex …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Protein Synthesis Inhibitors …
Matched Products: … Spotex …
Displaying drugs 1051 - 1075 of 1094 in total