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Displaying drugs 101 - 125 of 1261 in total

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …

Von Willebrand factor human

The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … and hemophilia A. ... vessel injury and stabilizing procoagulant factor VIII (FVIII). ... It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Dettol Moisturising Formula Antiseptic Cream ... Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap ... Benzocaine and Triclosan …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Antibacterial Mandarin and Grapefruit Handsoap Gentle Cleansing Formula ... Topco Antibacterial ... G-995 - Lot Top 0.1% …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover ... [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient …
Matched Mixtures name: … Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Erythromycin and Benzoyl Peroxide …
Matched Products: … Acne Face and Body ... Acne Face and Body Wash ... 5% BP Face and Body Wash …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and …
Matched Mixtures name: … Sildec ... Sildec DM ... Cold and Flu Medicine - Day Time Formula …
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Up and Up Suphedrine ... UP AND UP nasal decongestant ... Up and Up 12 Hour Nasal Decongestant …

Spanlecortemlocel

Investigational
Matched Synonyms: … Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and ... ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 …

Capsaicin

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … Silvera Pain Relief Patch ... Zostrix Diabetic Joint and Arthritis Pain Relief ... Satohap Cool and Hot Pads …
Matched Categories: … Basic Lotions and Liniments ... Capsaicin and Similar Agents ... Topical Products for Joint and Muscular Pain …
Matched Products: … beeRX Muscle and Joint Pain Relief ... Sherman and Clark Pain Relieving ... Miracle Plus Neck and Shoulder Pain Relief …

Indocyanine green acid form

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Categories: … Liver Function …
Matched Products: … Spy Agent Green Kit for Advanced Imaging Modality (aim) and Pinpoint ... Spy Agent Green Lymphatics Kit for Advanced Imaging Modality (aim) and Pinpoint …

Anti-inhibitor coagulant complex

Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex. It is used to control bleeding in hemophilia A and B patients with inhibitors.
Approved
Investigational
Matched Synonyms: … Activated prothrombin complex concentrate …
Matched Description: … It is used to control bleeding in hemophilia A and B patients with inhibitors. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … FEIBA (Factor VIII Inhibitor Bypassing Activity) 25U/ml Powder and solvent for solution for infusion ... FEIBA (Factor VIII Inhibitor Bypassing Activity) 50U/ml Powder and solvent for solution for infusion …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Linvoseltamab

Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …

GTP-506

GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …

Rumex acetosella pollen

Rumex acetosella pollen is the pollen of the Rumex acetosella plant. Rumex acetosella pollen is mainly used in allergenic testing.
Approved
Matched Synonyms: … sheep sorrel pollen extract …
Matched Mixtures name: … Dock Mix, Sour Sheep Sorrel/yellow Pollen …
Matched Products: … Pollens - Weeds and Garden Plants, Sorrel, Sheep Rumex acetosella ... Sheep Sorrel ... Sheep Red Sorrel …

Polyethylene glycol

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [A190975] Molecular weights of PEGs vary by time of the polymerization process and the molecular weight ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. ... PEGs differ in their physical and chemical properties depending on their molecular weight: PEGs are liquids …
Matched Mixtures name: … Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350 and Electrolytes ... HalfLytely and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Sound Body Clearlax ... Polyethylene Glycol 3350 and Electrolytes ... Up and Up Powderlax …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows ... It is available as immediate- and extended-release formulations. …
Matched Categories: … Bodily Secretions ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG ... BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and …
Matched Mixtures name: … Top Care Flu and Sore Throat ... Topco tussin cf max ... Goyescas 7 Syrups with Bee Honey Cough and Cold …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac …
Matched Products: … Up and Up nasal decongestant PE ... CareOne Cold and Sinus ... Up and Up Sinus PE …

Tolnaftate

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Description: … and ringworm. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot ... It is sold under several brand names, most notably Tinactin and Odor Eaters. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Signature Black Bottle Tea Tree Antifungal Foot and Body Wash ... Tinactin Jock Itch Top Aer Pwr 10mg/gm ... Up and Up Soothing Antifungal …

Sarocladium strictum

Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … It is a natural source of nitrate and has been used as a constituent for several different purposes, ... including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. ... In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. …
Matched Mixtures name: … Up and UP Sensitive Toothpaste Enamel Strengthening formula ... Up and UP Sensitive Toothpaste Enamel Strengthening formula plus whitening ... Top Care Enamel Guard …
Matched Products: … Schmidts WONDERMINT TOOTH AND MOUTH ... SprinJene Natural Sensitivity and Gum …

Panthenol

Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair ... P1P Chitosan V-mask …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BABOR Baborganic Calm and Relax ... bdr Re-fine pore minimizing fluid complex ... Roota Re V Tonic …

Chlorine dioxide

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Name: … Chlorine dioxide …
Matched Description: … Chlorine Dioxide has been used in trials studying the treatment of Halitosis. …
Matched Products: … Disinfectant and Sanitizer ... Chlorine Dioxide Air Disinfectant …

Coal tar

Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds. It has been...
Approved
Matched Description: … It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea ... Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and ... and eczema. …
Matched Mixtures name: … Pete and Pedro …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Displaying drugs 101 - 125 of 1261 in total