Displaying drugs 126 - 150 of 2722 in total
Cotsiranib
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Famotidine
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis ... and gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. …
Matched Mixtures name: … Up and Up dual action acid controller complete ... Up and Up Acid Controller Complete Dual Action ... Berkley and Jensen Acid Controller Complete …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Products: … Up and Up Acid Reducer Original Strength ... Up and Up acid reducer original strength ... Berkley and Jensen Acid Controller …
Matched Mixtures name: … Up and Up dual action acid controller complete ... Up and Up Acid Controller Complete Dual Action ... Berkley and Jensen Acid Controller Complete …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Products: … Up and Up Acid Reducer Original Strength ... Up and Up acid reducer original strength ... Berkley and Jensen Acid Controller …
Methyl salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxybenzoic acid methyl ester …
Matched Description: … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. ... It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating …
Matched Mixtures name: … Sunset Pain Relief Heating Camphor and Amino Acids ... Sports Balm ... Sports Balm …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … Jason Cooling Minerals and Tea Tree Pain Therapy ... Neuro Max Pain and Muscle Relief Gel ... Foot Works Arthritis Achy Foot and Muscle …
Matched Description: … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. ... It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating …
Matched Mixtures name: … Sunset Pain Relief Heating Camphor and Amino Acids ... Sports Balm ... Sports Balm …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … Jason Cooling Minerals and Tea Tree Pain Therapy ... Neuro Max Pain and Muscle Relief Gel ... Foot Works Arthritis Achy Foot and Muscle …
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and ... With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and ... With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Taniraleucel
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Witch hazel
Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Skin and Mucous Membrane Agents ... Astringents and Deodorants ... Herbs and Natural Products …
Matched Products: … What Happened Last Night ... Too Much Fun In The Sun ... 28 Remedy Radiance Night Moisturizer …
Matched Categories: … Skin and Mucous Membrane Agents ... Astringents and Deodorants ... Herbs and Natural Products …
Matched Products: … What Happened Last Night ... Too Much Fun In The Sun ... 28 Remedy Radiance Night Moisturizer …
Egg yolk
Egg yolk allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Animal Products and Poultry Products, Egg, Yolk Gallus sp. …
Triclosan
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap ... Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap ... Benzocaine and Triclosan …
Matched Categories: … Fatty Acid Synthesis Inhibitors ... Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Manosan ... A-Septic AS Gel ... Sport Gel Antiseptic Soap …
Matched Mixtures name: … Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap ... Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap ... Benzocaine and Triclosan …
Matched Categories: … Fatty Acid Synthesis Inhibitors ... Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Manosan ... A-Septic AS Gel ... Sport Gel Antiseptic Soap …
Pseudoephedrine
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and …
Matched Mixtures name: … Smart Sense allergy and congestion relief indoor and outdoor allergies ... Benylin Extra Strength Mucus & Phlegm Plus Cold Relief Night ... Night Time Cold and Flu …
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Up and Up Suphedrine ... Up and Up 12 Hour Nasal Decongestant ... UP AND UP nasal decongestant …
Matched Mixtures name: … Smart Sense allergy and congestion relief indoor and outdoor allergies ... Benylin Extra Strength Mucus & Phlegm Plus Cold Relief Night ... Night Time Cold and Flu …
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Up and Up Suphedrine ... Up and Up 12 Hour Nasal Decongestant ... UP AND UP nasal decongestant …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pacanalotamab
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and …
Zinc oxide
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Description: … lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and ... It is also widely used to treat a variety of other skin conditions, in products such as baby powder and ... barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments …
Matched Mixtures name: … Sirot Hand and Body Trio Transformative glass Technology Complete Age Resistance Day and Night ... Sirot Hand and Body Trio Transformative Glass Technology Complete Age Resistance Day and Night ... SIROT 24-Hour Hand Care Transformative Glass Technology Age-Fighting Protection Day and Night …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Basic Ointments and Protectants ... Basic Powders and Demulcents …
Matched Products: … Inde Wild ... Babo Botanicals Swim and Sport Mineral Sunscreen SPF 30 ... Babo Botanicals Swim and Sport Mineral Sunscreen Balm SPF 50 …
Matched Mixtures name: … Sirot Hand and Body Trio Transformative glass Technology Complete Age Resistance Day and Night ... Sirot Hand and Body Trio Transformative Glass Technology Complete Age Resistance Day and Night ... SIROT 24-Hour Hand Care Transformative Glass Technology Age-Fighting Protection Day and Night …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Basic Ointments and Protectants ... Basic Powders and Demulcents …
Matched Products: … Inde Wild ... Babo Botanicals Swim and Sport Mineral Sunscreen SPF 30 ... Babo Botanicals Swim and Sport Mineral Sunscreen Balm SPF 50 …
Clotrimazole
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … CANDID-B CREAM ... CANDID-B CREAM ... CANDID B LOTION …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CANDID V GEL ... CANDID - V 3 ... CANDID CREAM 1% …
Matched Mixtures name: … CANDID-B CREAM ... CANDID-B CREAM ... CANDID B LOTION …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … CANDID V GEL ... CANDID - V 3 ... CANDID CREAM 1% …
Suratadenoturev
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... telomerase reverse transcriptase (hTERT) and IRES, respectively. ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Polyethylene glycol
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [A190975] Molecular weights of PEGs vary by time of the polymerization process and the molecular weight ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. ... PEGs differ in their physical and chemical properties depending on their molecular weight: PEGs are liquids …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350 and Electrolytes …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Polyethylene Glycol 3350 and Electrolytes ... Up and Up Powderlax ... POLYETHYLENE GLYCOL 3350 AND ELECTROLYTES With flavor packs …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate ... PEG-3350 and Electrolytes …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Polyethylene Glycol 3350 and Electrolytes ... Up and Up Powderlax ... POLYETHYLENE GLYCOL 3350 AND ELECTROLYTES With flavor packs …
Povidone-iodine
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Shelanski and M. V. Shelanski. ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Frepp Sepp Kit ... Frepp Sepp Kit ... Physician EZ Use Joint Tunnel and Trigger Kit …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ERPHA-SEPTAN ... PVP-Iodine Sepp ... SEPSO J SALBE …
Matched Mixtures name: … Frepp Sepp Kit ... Frepp Sepp Kit ... Physician EZ Use Joint Tunnel and Trigger Kit …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … ERPHA-SEPTAN ... PVP-Iodine Sepp ... SEPSO J SALBE …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Synonyms: … Nicotinic acid amide …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Hydra Moisture Day and Night ... Skinmd Labratories Day and Night Brightening ... Cell Power Night …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Hydra Moisture Day and Night ... Skinmd Labratories Day and Night Brightening ... Cell Power Night …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Products: … Dr.g Lock and More A-clear Mask ... P8 Tone - Up and Brightening CreamEX ... HANSKIN BiO FILL PEP MASK Firming and Moisture …
Dendryphiella vinosa
Dendryphiella vinosa is a fungus which can provoke allergic reactions. Dendryphiella vinosa extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Helminthosporium interseminatum …
Calcium polycarbophil
Calcium polycarbophil is a stool stabilizer. Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. Polycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel...
Approved
Matched Description: … It is insoluble in water, dilute acids, and dilute alkali. ... Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps ... digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Fiber Therapy ... Foster and Thrive Fiber Laxative 147 …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Fiber Therapy ... Foster and Thrive Fiber Laxative 147 …
Mesocricetus auratus skin
Mesocricetus auratus skin or pelt is used in allergenic testing.
Approved
Matched Products: … Hamster Hair and Epithelia …
Cod, unspecified
Cod, unspecified allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Fish and Shellfish, Codfish Gadus callarias …
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … American Fare Nicotine Transdermal System ... Up and Up Nicotine ... Up and Up Nicotine Polacrilex …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … American Fare Nicotine Transdermal System ... Up and Up Nicotine ... Up and Up Nicotine Polacrilex …
Urofollitropin
Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified from human urine samples. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51...
Approved
Vet approved
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... Urofollitropin is a urinary-derived follicle-stimulating hormone (FSH) that is extracted and purified ... 7 and Asn 24. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU ... Fostimon 75 IU powder and solvent for solution for injection ... Fostimon 150 IU powder and solvent for solution for injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU ... Fostimon 75 IU powder and solvent for solution for injection ... Fostimon 150 IU powder and solvent for solution for injection …
Cyclomethicone 5
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and ... Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Matched Products: … Mefactory Super Clear Lip And Eye Remover ... 3ce CR Eamy Water Proof Eye Liner 13 Caffeine …
Matched Products: … Mefactory Super Clear Lip And Eye Remover ... 3ce CR Eamy Water Proof Eye Liner 13 Caffeine …
Displaying drugs 126 - 150 of 2722 in total