Displaying drugs 151 - 175 of 12418 in total
Enasidenib
Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. Patients eligible for this treatment...
Approved
Investigational
Matched Synonyms: … trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol …
Matched Iupac: … trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl}amino)propan-2-ol …
Matched Description: … Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory ... This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and ... Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood …
Matched Iupac: … trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl}amino)propan-2-ol …
Matched Description: … Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory ... This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and ... Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood …
Propranolol
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907]
Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …
Elacestrant
Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.[A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer.[L44918,L44948] It received a similar approval in the EU in September 2023. Elacestrant binds to estrogen receptor-alpha (ERα)...
Approved
Investigational
Matched Synonyms: … (2R)-2-(2-(ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol ... ethyl((4-(2- (ethylamino)ethyl)phenyl)methyl)amino)-4-methoxyphenyl)- 5,6,7,8-tetrahydronaphthalen-2-ol …
Matched Iupac: … [ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol …
Matched Description: … a SERD represents a therapeutic approach for the treatment of endocrine-resistant breast cancers. ... [A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative ... (SERMs) and aromatase inhibitors (AIs), may lead to drug resistance over time; therefore, the use of …
Matched Iupac: … [ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol …
Matched Description: … a SERD represents a therapeutic approach for the treatment of endocrine-resistant breast cancers. ... [A256838,L44918] In January 2023, it was approved by the FDA for the treatment of ER-positive, HER2-negative ... (SERMs) and aromatase inhibitors (AIs), may lead to drug resistance over time; therefore, the use of …
Cefotiam
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Tuberculin purified protein derivative
Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with Mycobacterium tuberculosis...
Approved
Matched Synonyms: … Purified protein derivative of tuberculin …
Matched Description: … The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium ... for intradermal administration as an aid in the diagnosis of tuberculosis. ... It is included in the World Health Organization's List of Essential Medicines. …
Matched Description: … The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium ... for intradermal administration as an aid in the diagnosis of tuberculosis. ... It is included in the World Health Organization's List of Essential Medicines. …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Synonyms: … 3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol ... 6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … (THCA-A) and cannabidiolic acid (CBDA), through decarboxylation reactions. ... DB00486]), THC and CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A ... , a class of compounds that act upon endogenous cannabinoid receptors of the body [A32584]. …
Matched Iupac: … (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6H,6aH,7H,8H,10aH-benzo[c]isochromen-1-ol …
Matched Description: … (THCA-A) and cannabidiolic acid (CBDA), through decarboxylation reactions. ... DB00486]), THC and CBD are obtained through conversion from their precursors, tetrahydrocannabinolic acid-A ... , a class of compounds that act upon endogenous cannabinoid receptors of the body [A32584]. …
Thiamylal
A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)
Approved
Vet approved
Matched Synonyms: … 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid …
Matched Description: … A barbiturate that is administered intravenously for the production of complete anesthesia of short duration ... , for the induction of general anesthesia, or for inducing a hypnotic state. …
Matched Categories: … combinations of barbiturates …
Matched Description: … A barbiturate that is administered intravenously for the production of complete anesthesia of short duration ... , for the induction of general anesthesia, or for inducing a hypnotic state. …
Matched Categories: … combinations of barbiturates …
Hydroxyethyl ethylcellulose
Hydroxyethyl ethylcellulose modulates bacterial binding to salivary pellicle; moderately effective in preventing plaque formation.
Approved
Experimental
Matched Synonyms: … 2-hydroxyethyl ether of ethyl cellulose …
Cefazolin
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Iupac: … methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Nitric Oxide
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Matched Description: … This gas is an important signaling molecule in the body of mammals including humans and is an extremely ... It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown …
Matched Products: … NO more Eye Pain (Relieves dryness of the eye, Protects against irritaion of the eye) redness of the ... roots extract Mesoporous Silica Nanoparticle Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid ... roots extract Mesoporous Silica Nanoparticle, Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid …
Matched Products: … NO more Eye Pain (Relieves dryness of the eye, Protects against irritaion of the eye) redness of the ... roots extract Mesoporous Silica Nanoparticle Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid ... roots extract Mesoporous Silica Nanoparticle, Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid …
Pyrethrum extract
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins component of rid mousse …
Matched Description: … Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. ... While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities …
Matched Description: … Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. ... While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities …
Diclofenamide
A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 4,5-dichloro-benzene-1,3-disulfonic acid diamide …
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …
Tofersen
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more ... [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more …
Matched Description: … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more ... [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro ... Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro …
Matched Description: … of myocardial infarction (MI) or with peripheral arterial disease (PAD). ... Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Matched Description: … of myocardial infarction (MI) or with peripheral arterial disease (PAD). ... Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Allopurinol
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals .
Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Synonyms: … 1H-Pyrazolo(3,4-d)pyrimidin-4-ol …
Matched Iupac: … 1H-pyrazolo[3,4-d]pyrimidin-4-ol …
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Matched Iupac: … 1H-pyrazolo[3,4-d]pyrimidin-4-ol …
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially ... Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective …
Matched Categories: … Preparations Inhibiting Uric Acid Production …
Atidarsagene autotemcel
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid …
Matched Description: … certain manifestations of metachromatic leukodystrophy (MLD). ... in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of …
Matched Description: … certain manifestations of metachromatic leukodystrophy (MLD). ... in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of …
Selenium
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase ... , an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species …
Matched Products: … Selenious Acid …
Matched Products: … Selenious Acid …
Dimercaprol
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Synonyms: … 2,3-mercaptopropan-1-ol …
Matched Iupac: … 2,3-disulfanylpropan-1-ol …
Matched Description: … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. ... In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in …
Matched Iupac: … 2,3-disulfanylpropan-1-ol …
Matched Description: … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. ... In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in …
Scopolamine
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester …
Matched Description: … Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar ... to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine ... [A228423, A228758] As a result of its anticholinergic effects, scopolamine is being investigated for …
Matched Description: … Scopolamine is a tropane alkaloid isolated from members of the _Solanaceae_ family of plants, similar ... to [atropine] and [hyoscyamine], all of which structurally mimic the natural neurotransmitter [acetylcholine ... [A228423, A228758] As a result of its anticholinergic effects, scopolamine is being investigated for …
Soybean
Soybean allergenic extract is used in allergenic testing.
Approved
Matched Products: … Babor Cleansing Hy-OL …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … ad5) vector encoding the human interferon alpha 2 (ifna2, interferon alpha-2b) gene under the control of …
Matched Description: … alternatives for the treatment of BCG-unresponsive NMIBC. ... The localized expression of this gene induces anti-tumor effects. ... It is the first gene therapy approved by the FDA for the treatment of bladder cancer. …
Matched Description: … alternatives for the treatment of BCG-unresponsive NMIBC. ... The localized expression of this gene induces anti-tumor effects. ... It is the first gene therapy approved by the FDA for the treatment of bladder cancer. …
Magnesium
Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … (RDI) of magnesium. ... as food processing and cooking vegetables (which are normally a rich source of magnesium). ... [A19349]
Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... Herbs of Gold B Complex Plus Softgel …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules …
Matched Mixtures name: … Calcium Folic Acid Plus D Chewable ... Herbs of Gold B Complex Plus Softgel …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules …
Nelumbo nucifera flower
Nelumbo nucifera flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Bean of India Flower …
Hydroquinone
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... product found in OTC products, and is used to correct skin discoloration associated with disorders of …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% ... Hyaluronic Acid Sodium Salt 0.5% / Hydroquinone 4% / Tretinoin 0.05% ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots …
Matched Products: … Celazome Fade Shades Lightening Cream w/ Glycolic Acid …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% ... Hyaluronic Acid Sodium Salt 0.5% / Hydroquinone 4% / Tretinoin 0.05% ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots …
Matched Products: … Celazome Fade Shades Lightening Cream w/ Glycolic Acid …
Displaying drugs 151 - 175 of 12418 in total