Magnesium

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Magnesium
Accession Number
DB14513
Type
Small Molecule
Groups
Approved, Experimental, Investigational
Description

A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.

Structure
Thumb
Synonyms
  • Magnesio
  • Magnésium
  • Magnesium metallicum
  • Magnesium powder
  • Mg
Active Moieties
NameKindUNIICASInChI Key
Magnesium oxideunknown3A3U0GI71G1309-48-4AXZKOIWUVFPNLO-UHFFFAOYSA-N
Magnesium cationionicT6V3LHY83822537-22-0JLVVSXFLKOJNIY-UHFFFAOYSA-N
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Acti Mag 250 CapletTablet250 mgOralActi Form Ltd.1991-12-312005-03-21Canada
Chelated Magnesium 150mg - TabTablet150 mgOralHealth Wise Nutrition Inc.1997-08-152000-07-29Canada
Chelated Magnesium Supplement - Tab 100mgTablet100 mgOralAlbion1996-09-062007-10-19Canada
Chelated Magnesium Tab 50mgTablet50 mgOralJamieson Laboratories Ltd1975-12-312001-09-14Canada
Chelazome Magnesium 100mgTablet100 mgOralTrophic Canada Ltd.1987-12-312000-08-03Canada
F.M. FormulaCapsule80 mgOralNatures Sunshine Products, Inc.1999-05-252009-08-07Canada
MagnelisCapsule165 mgOralImport Export SantÉ Nature Inc.1999-02-202003-08-01Canada
MagnesiumCapsule20 mgOralFrega Inc.1981-12-312008-02-13Canada
Magnesium - 100mg TabTablet100 mgOralMetagenics, Inc.1997-02-012008-08-28Canada
Magnesium 150 mgCapsule150 mgOralRegime Industries Ltd.2002-08-282009-07-17Canada
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
24 Multivitamins + MineralsMagnesium (65 mg) + Ascorbic acid (150 mg) + Beta carotene (10000 unit) + Biotin (25 mcg) + Calcium (130 mg) + Cholecalciferol (400 unit) + Choline bitartrate (25 mg) + Chromium (20 mcg) + Copper (1 mg) + Cyanocobalamin (25 mcg) + Ferrous fumarate (15 mg) + Folic acid (.8 mg) + Inositol (25 mg) + Manganese (2 mg) + Molybdenum (20 mcg) + Niacin (25 mg) + Calcium pantothenate (25 mg) + Potassium (15 mg) + Potassium Iodide (.1 mg) + Pyridoxine hydrochloride (25 mg) + Racemethionine (25 mg) + Riboflavin (25 mg) + Selenium (20 mcg) + Thiamine hydrochloride (25 mg) + Vanadium (20 mcg) + Vitamin A palmitate (5000 unit) + Vitamin E (50 unit) + Zinc (10 mg)TabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-04-302002-07-31Canada
50 Plus Multiple Vitamins & MineralsMagnesium (100 mg) + Ascorbic acid (90 mg) + Biotin (45 mcg) + Calcium (200 mg) + Cholecalciferol (400 unit) + Chromium (10 mcg) + Copper (2 mg) + Cyanocobalamin (25 mcg) + Folic acid (0.4 mg) + Manganese (5 mg) + Molybdenum (25 mcg) + Nicotinamide (40 mg) + Pantothenic acid (10 mg) + Potassium Iodide (0.15 mg) + Pyridoxine hydrochloride (3 mg) + Riboflavin (3.2 mg) + Selenium (25 mcg) + Thiamine mononitrate (2.25 mg) + Vanadium (10 mcg) + Vitamin A palmitate (6000 unit) + Zinc (15 mg)TabletOralGfr Pharma Ltd.2002-10-202004-06-15Canada
Acetabolan III Vitamin and Mineral SupplementMagnesium (112.5 mg) + Ascorbic acid (250.0 mg) + Pyridoxine hydrochloride (2.63 mg) + Zinc (7.5 mg)CapsuleOralIovate Health Sciences International Inc.2003-12-052007-07-18Canada
Acetabolan-II Vitamin and Mineral SupplementMagnesium (90 mg) + Ascorbic acid (200 mg) + Pyridoxine hydrochloride (2.1 mg) + Zinc (6 mg)CapsuleOralIovate Health Sciences International Inc.2000-11-202005-06-21Canada
Acti-cal/mag 2:1 + Zinc and D CapletMagnesium (175.0 mg) + Calcium (350.0 mg) + Cholecalciferol (100 unit) + Zinc (6.0 mg)TabletOralActi Form Ltd.1991-12-312005-03-21Canada
Actical Plus Calcium-magnesium-vitamin D3-silicon ChewableMagnesium (100 mg) + Calcium (200 mg) + Cholecalciferol (100 unit) + Silicon (2 mg)TabletOralUsana Health Sciences, Inc.1999-09-302004-07-27Canada
Active Calcium Plus Magnesium, Vitamin D and SiliconMagnesium (100 mg) + Calcium (200 mg) + Cholecalciferol (100 unit) + Silicon (2.25 mg)TabletOralUsana Health Sciences, Inc.2002-07-082007-07-18Canada
ActyformMagnesium (61.15 mg) + Copper (1 mg) + Iron (4.18 mg) + Zinc (9 mg)CapsuleOralTechnodiet S.E.N.C.1999-10-262008-08-13Canada
Advanced B & T FormulaMagnesium (83.3 mg) + Ascorbic acid (33.3 mg) + Calcium (200 mg) + Chromium (33.33 mcg) + Copper (0.5 mg) + Cyanocobalamin (6.67 mcg) + Folic acid (0.133 mg) + Iron (1.67 mg) + Manganese (3.33 mg) + Nicotinamide (6.67 mg) + Calcium pantothenate (5 mg) + Phosphorus (100 mg) + Potassium (16.67 mg) + Pyridoxine hydrochloride (6.67 mg) + Riboflavin (2.67 mg) + Selenium (33.33 mcg) + Silicon (0.333 mg) + Sodium molybdate (16.67 mcg) + Thiamine (2.67 mg) + Vanadium (8.33 mg) + Vitamin D (66.67 unit) + Zinc (5 mg)CapsuleOralNutraceutical CorporationNot applicableNot applicableCanada
ArmaxMagnesium (50 mg) + Ascorbic acid (15 mg) + Manganese (1.5 mg) + Niacin (15 mg) + Nicotinamide (150 mg) + Calcium pantothenate (50 mg) + Zinc (1.5 mg)TabletOralEnzymatic Therapy, Inc.1997-03-202001-08-02Canada
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
C-Nate DHAMagnesium (30 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (1 mg/1) + Cyanocobalamin (15 ug/1) + Ferrous fumarate (28 mg/1) + Folic acid (1 mg/1) + Omega-3 fatty acids (200 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3 mg/1) + Thiamine mononitrate (3 mg/1) + Vitamin E (30 [iU]/1) + Zinc oxide (20 mg/1)Capsule, gelatin coatedOralCenturion Labs2013-01-01Not applicableUs
Calcium Folic Acid Plus D ChewableMagnesium (50 mg/1) + Boron (250 ug/1) + Calcium Carbonate (1342 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 ug/1) + Folic acid (1 mg/1) + Pyridoxine (10 mg/1)WaferOralAcella Pharmaceuticals, LLC2009-03-20Not applicableUs
Cavan-EC SOD DHAMagnesium (25 mg/1) + Ascorbic acid (130 mg/1) + Beta carotene (3000 [iU]/1) + Calcium (230 mg/1) + Cholecalciferol (410 [iU]/1) + Copper (2 mg/1) + Cyanocobalamin (12 ug/1) + Folic acid (1 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (440 mg/1) + Pyridoxine hydrochloride (28 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (30 mg/1) + Thiamine mononitrate (1.8 mg/1) + Vitamin E (30 mg/1) + Zinc (26 mg/1)KitOralSeton Pharmaceuticals2010-01-102014-07-15Us
Duet DHA BalancedMagnesium (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2480 [iU]/1) + Calcium Carbonate (215 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + D-alpha-Tocopherol acetate (2 mg/1) + Folic acid (1 mg/1) + Iodine (210 ug/1) + Iron (26 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (278 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (1.5 mg/1) + Zinc oxide (25 mg/1)KitOralEckson Labs, LLC2012-10-302014-10-31Us
Duet DHA BalancedMagnesium (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2800 [iU]/1) + Calcium Carbonate (215 mg/1) + Cholecalciferol (640 [iU]/1) + Choline (55 mg/1) + Cupric oxide (1.8 mg/1) + Cyanocobalamin (12 ug/1) + D-alpha-Tocopherol acetate (15 mg/1) + Folic acid (1 mg/1) + Iodine (210 ug/1) + Iron (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (267 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (2 mg/1) + Sodium selenate (65 ug/1) + Thiamine mononitrate (1.5 mg/1) + Zinc oxide (25 mg/1)KitEckson Labs, LLC2012-10-30Not applicableUs
EscaviteMagnesium (60 mg/1) + Ascorbic acid (100 mg/1) + Biotin (45 ug/1) + Cholecalciferol (400 [iU]/1) + Copper (1 mg/1) + Cyanocobalamin (9 ug/1) + Folic acid (0.4 mg/1) + Iron (7.5 mg/1) + Nicotinamide (20 mg/1) + Calcium pantothenate (10 mg/1) + Pyridoxine hydrochloride (2 mg/1) + Riboflavin (1.7 mg/1) + Sodium fluoride (0.25 mg/1) + Thiamine mononitrate (1.5 mg/1) + Vitamin A acetate (1000 [iU]/1) + Zinc (7.4 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)Tablet, chewableOralGm Pharmaceuticals2012-02-01Not applicableUs
Folcaps Care OneMagnesium (50 mg/1) + Alpha-Linolenic Acid (50 mg/1) + Biotin (300 mg/1) + Calcium Carbonate (100 mg/1) + Calcium ascorbate dihydrate (24 mg/1) + Calcium threonate (1 mg/1) + Cholecalciferol (800 [iU]/1) + Doconexent (350 mg/1) + Docusate sodium (50 mg/1) + Folic acid (1 mg/1) + Icosapent (100 mg/1) + Iodine (150 ug/1) + Iron (27 mg/1) + Nicotinamide (10 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (1.5 mg/1) + Zinc (5 mg/1) + alpha-Tocopherol acetate (15 [iU]/1)Capsule, gelatin coatedOralMayne Pharma2009-05-012016-12-31Us
Folet OneMagnesium (15 mg/1) + Ascorbic acid (18 mg/1) + Cholecalciferol (250 [iU]/1) + Cyanocobalamin (15 ug/1) + Doconexent (225 mg/1) + Docusate sodium (25 mg/1) + Folic acid (1 mg/1) + Iron (38 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Vitamin E (15 [iU]/1) + Zinc (20 mg/1)Capsule, liquid filledOralPronova Corporation2014-06-01Not applicableUs
MaxFeMagnesium (6.5 mg/1) + Ascorbic acid (100 mg/1) + Biotin (150 ug/1) + Cyanocobalamin (60 ug/1) + Docusate sodium (50 mg/1) + Folic acid (1 mg/1) + Iron (160 mg/1) + Zinc (12 mg/1)TabletOralPronova Corporation2014-06-01Not applicableUs
Moms Choice RxMagnesium (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2840 [iU]/1) + Calcium Carbonate (215 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric cation (2 mg/1) + Cyanocobalamin (.012 mg/1) + D-alpha-Tocopherol acetate (2 mg/1) + Folic acid (1 mg/1) + Iodine (.223 mg/1) + Iron (26 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (278 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine chloride (1.5 mg/1) + Zinc oxide (25 mg/1)KitPru Gen Pharmaceuticals2013-04-01Not applicableUs
Categories
UNII
I38ZP9992A
CAS number
7439-95-4
Weight
Average: 26.321
Monoisotopic: 26.00069176
Chemical Formula
H2Mg
InChI Key
RSHAOIXHUHAZPM-UHFFFAOYSA-N
InChI
InChI=1S/Mg.2H
IUPAC Name
magnesium dihydride
SMILES
[MgH2]

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
1alpha-Hydroxyvitamin D5The serum concentration of Magnesium can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
3-Aza-2,3-Dihydrogeranyl DiphosphateMagnesium can cause a decrease in the absorption of 3-Aza-2,3-Dihydrogeranyl Diphosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
AclidiniumThe therapeutic efficacy of Magnesium can be decreased when used in combination with Aclidinium.
AgmatineThe risk or severity of hypotension and neuromuscular blockade can be increased when Agmatine is combined with Magnesium.
AlcuroniumThe therapeutic efficacy of Magnesium can be decreased when used in combination with Alcuronium.
Alendronic acidMagnesium can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
AlfacalcidolThe serum concentration of Magnesium can be increased when it is combined with Alfacalcidol.
AlmasilateThe therapeutic efficacy of Magnesium can be decreased when used in combination with Almasilate.
AloglutamolThe therapeutic efficacy of Magnesium can be decreased when used in combination with Aloglutamol.
AluminiumThe therapeutic efficacy of Magnesium can be decreased when used in combination with Aluminium.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

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Food Interactions
Not Available

References

General References
Not Available
External Links
ChemSpider
16787263
ChEMBL
CHEMBL2146125
Wikipedia
Magnesium
AHFS Codes
  • 88:29.00* — Minerals
  • 88:28.00 — Multivitamin Preparations

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0Not Yet RecruitingTreatmentPain After TJA1
2RecruitingSupportive CareAutism Spectrum Conditions/Disorders1
3Active Not RecruitingTreatmentPancreatitis1
3Not Yet RecruitingTreatmentHeart Failure / Magnesium Deficiency1
3RecruitingPreventionPost-ERCP Pancreatitis1
4Not Yet RecruitingPreventionCoronary Artery Disease / Nonvalvular Atrial Fibrillation / Surgery--Complications1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TabletOral250 mg
CapsuleOral
Granule, effervescentOral
WaferOral
TabletOral150 mg
TabletOral50 mg
Tablet, extended releaseOral
KitOral
Tablet, effervescentOral
Tablet, chewableOral
CapsuleOral80 mg
PowderOral
CapsuleOral165 mg
TabletOral100 mg
CapsuleOral72.5 mg
CapsuleOral125 mg
CapsuleOral250 mg
CapsuleOral100 mg
CapsuleOral90 mg
CapsuleOral150 mg
TabletOral300 mg
CapsuleOral70 mg
LiquidOral114 mg
PowderOral240 mg
TabletOral252 mg
TabletOral70 mg
SolutionOral118.6 mg
TabletOral200 mg
LiquidOral23.92 mg
PowderOral119.6 mg
LiquidOral1 g
CapsuleOral20 mg
TabletOral
Kit
TabletOral36 mg
PlasterTopical3 g/100g
LiquidOral
LiquidOral10.24 mg
TabletOral188 mg
TabletOral375 mg
Capsule, gelatin coatedOral
Capsule, liquid filledOral
Tablet, delayed releaseOral64 mg
Tablet, coatedOral
Powder, for solutionOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity1.6 m3·mol-1ChemAxon
Polarizability3.27 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on July 12, 2018 10:17 / Updated on June 24, 2019 13:09