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Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … Acide tranéxamique ... Tranexamic acid ... Tranexmic acid
Matched Name: … Tranexamic acid
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Tranexamic acid ... Tranexamic Acid ... TRANEXAMIC ACID
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … Half and Half Balm ... Dermoplex Bite and Sting Cream ... Jack and Jill Rub …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) ... Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803 …
Matched Description: … 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG ... Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... Triethanolamine neutralizes the acidity of the salicylic acid. ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Synonyms: … Vitamin E (alpha tocopherol acetate) ... Tocopherol acetate ... Tocopheryl acetate
Matched Name: … alpha-Tocopherol acetate
Matched Description: … is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly ... Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals …
Matched Mixtures name: … Chunzam Silk Amino Acid Tooth ... Feminique W Iron and Calcium Tab ... Pregvit Folic 4 …
Matched Categories: … Diet, Food, and Nutrition ... Tocopherols
Matched Products: … Dl E 400 Cap 400unit …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Synonyms: … DL-panthenol ... DL-Pantothenol …
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Sensitive and Dry Hair ... Therapytion Nokmosu Neutral and oily Hair ... Medi All 4 Cleanser (NIACINAMIDE) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Matched Products: … BABOR Baborganic Calm and Relax …
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Synonyms: … Cyanocobalamin (60Co) ... Cyanocobalamin Co 60 ... Cyanocobalamine (60 Co) …
Matched Name: … Cyanocobalamin Co-60 …
Matched Description: … Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid nicotinamide complex ... Nicotinamide-ascorbic acid complex ... Niacinamide ascorbate …
Matched Name: … Niacinamide ascorbate …
Matched Iupac: … (5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-2,5-dihydrofuran-2-one; pyridine-3-carboxamide …
Matched Mixtures name: … Stress B Complex With C, E and Iron Tab ... Stress B Complex With C and E Tab ... Stress B Complex With C,e, Zinc and Copper …
Matched Categories: … Vitamin C and analogues …
Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst. In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins, DNA and RNA. Trichloroacetate is also found in cosmetic treatments and...
Approved
Matched Description: … , DNA and RNA. ... In clinical chemistry and biochemistry, it is used as a precipitant of macromolecules including proteins ... Trichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which …
Matched Salts name: … Trichloroacetic acid
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids ... Trichloroacetic Acid
Matched Products: … Trichloroacetic Acid 30% ... Trichloroacetic Acid 15% ... Trichloroacetic Acid 50% …
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and
Matched Mixtures name: … Herbal Iron Brilliant Performance for Brightening and Wrinkle Free ... Herbal Iron Brilliant Performance for Brightening and Wrinkle Free ... Herbal Iron Brilliant Performance for Brightening and Wrinkle Free …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … rootree Treetherapy Rejuvenating Eye and Neck Treatment ... misoli Power Snail and Collagen Hydrog el Mask Pack ... Mizon Hyaluronic Acid 100 …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Iupac: … heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoic acid
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate ... Neomycin and Polymyxin B Sulfates and Bacitracin Zinc with Hydrocortisone Acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid …
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Synonyms: … phenylbenzimidazole sulfonic acid
Matched Iupac: … 2-phenyl-1H-1,3-benzodiazole-6-sulfonic acid
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that ... It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less …
Matched Mixtures name: … Polyglutamic Acid Dewy Sunscreen SPF 30 ... Alpha Hydrox Moisturizing Daily Lotion SPF 15 ... Advanced Firming and Anti Wrinkle …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Products: … Dolce and Gabbana The Foundation Perfect Matte Broadspectrum SPF 20 All shades ... Lancome Paris Teint Idole Ultra Care and Glow Skincare Foundation Broad Spectrum SPF 27 Sunscreen …
Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358][FDA Label]. Fluticasone propionate was first approved in 1990 .
Approved
Matched Description: … These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory …
Matched Mixtures name: … Azelastine hydrochloride and Fluticasone propionate ... Azelastine Hydrochloride and Fluticasone Propionate ... Azelastine Hydrochloride and Fluticasone Propionate …
Matched Products: … Up and Up Allergy Relief Nasal ... Up and Up allergy relief nasal ... Berkley and Jensen Allergy Relief …
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1 ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids
Matched Mixtures name: … Cepacol Sore Throat and Coating ... Kaolin and Pectin Susp ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ... POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-CARBOXY-.OMEGA. …
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia ... , and mixed dyslipidemia. …
Matched Categories: … Peroxisome Proliferator Receptor alpha Agonist ... Acids, Acyclic ... Fibric Acids ... Carboxylic Acids
Matched Products: … Fenofibric Acid ... Fenofibric acid ... Fenofibric Acid Delayed-Release …
Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a...
Investigational
Matched Synonyms: … Recombinant fusion protein of Mycobacterium bovis BCG Hsp65 and HPV16 E7 …
Matched Description: … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen ... recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and ... Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be …
Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …
Approved
Experimental
Investigational
Matched Synonyms: … DL-alpha tocopherol ... Vitamin E DL-alpha ... DL-α-tocopherol
Matched Name: … DL-alpha-Tocopherol
Matched Mixtures name: … Eden With Vitamins A, C, and E ... Folica-V ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … FSH alpha ... rFSH-alpha ... Follitrophin alpha
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... Numerous physio-chemical tests and bioassays indicate that follitropin beta and follitropin alpha are ... The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu ... MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid
Matched Description: … Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and
Matched Mixtures name: … Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA ... PNV Ferrous Fumarate Docusate Folic Acid ... Iron
Matched Categories: … Alimentary Tract and Metabolism ... Softener and Emollient Laxatives …
Matched Products: … Up and up stool softener ... Stool Softener easy and gentle …
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … alpha-Tocopheryl acid succinate ... d-alpha-Tocopherol acid succinate ... Tocopheryl acid succinate,D-alpha
Matched Name: … alpha-Tocopherol succinate …
Matched Iupac: … 2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy}butanoic acid
Matched Description: … that are unique from the alpha-tocopherol form and other alpha-tocopherol esters [L2699, A32958, A32959 ... is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... , making a compound such as alpha-tocopherol succinate more stable and easier to use in vitamin supplements …
Matched Mixtures name: … Folic Acid Plus ... Multi-Vitamin Fluoride and Iron Drops ... Multi Vitamin Drops with Fluoride and Iron
Matched Categories: … Diet, Food, and Nutrition ... Tocopherols
Displaying drugs 301 - 325 of 3054 in total