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Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Synonyms: … Salicylic acid ... Acidum salicylicum ... 2-Hydroxybenzoic acid …
Matched Name: … Salicylic acid …
Matched Iupac: … 2-hydroxybenzoic acid …
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Urea 39.5% with 2% Salicylic Acid ... Dermaharmony Sulfur and Salicylic Acid ... Dermaharmony Sulfur and Salicylic Acid …
Matched Categories: … Salicylic Acid and Derivatives ... Genito Urinary System and Sex Hormones ... sodium salicylate and methenamine ... Acids, Carbocyclic ... Hydroxy Acids …
Matched Products: … Doctor Lead M ... DOCTOR LEAD M 500mL ... Sulfur 8 Loc Twist and Braid Scalp …

RP-72

Investigational
Matched Synonyms: … 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin ... CXC chemokine receptor types 1 and 2 inhibitor RP72 …

Penicillium glaucum

Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus ... Penicillium glaucum whole …

Givastomig

Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 and 4.1BB Bispecific Antibody …
Matched Description: … Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody. …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … as a result, leads to easy bruising and bleeding. ... results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of fibrinogen ... Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000IU/VIAL …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Gentle and Effective Laxative Enteric Coated ... Up and Up womens laxative ... Up and Up Gentle Laxative …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and ... Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Synonyms: … Cortisol …
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named ... Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. …
Matched Mixtures name: … HYDROCORTISONE 1% ET UREA 5% CREAM ... NEO-CORTISONE CREAM ... NEO-CORTISONE CREAM …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Hydrocortisone and derivatives ... Sex Hormones and Insulins ... hydrocortisone and mydriatics …
Matched Products: … HYDROCORTISON ACIS 10MG ... OREAD GOLD Anti-Itch Foam ... Hydrocortisone Rectal Suspension (Retention) …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... are D-amino acids. …
Matched Salts name: … Degarelix acetate hydrate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Salts name: … Pasireotide acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Somatostatin and Analogues ... Sex Hormones and Insulins …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and ... As a result of these concerns, hydroquinone has been banned in the EU and UK. …
Matched Mixtures name: … Top White ... Top White Skin Lightening ... CREMA CON ACIDO GLICOLICO AL 8% …
Matched Products: … Gold Cosmetics Bleach Cream Silver ... Celazome Fade Shades Lightening Cream w/ Glycolic Acid ... Gold Cosmetics Adi Clear …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Silver Leather ... Axe Signature Gold Dry Antiperspirant ... Secret Invisible Boho Berry …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Carbonic acid calcium salt (1:1) ... Calcio carbonato ... Calcium carbonate …
Matched Name: … Calcium carbonate …
Matched Iupac: … calcium carbonate …
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. ... It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. ... Calcium carbonate is an inorganic salt used as an antacid. …
Matched Mixtures name: … Recal D ... CVS Berry Antacid Heartburn and Gas ... Mixed Berry Antacid and Anti-Gas Chews …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Antacids and Adsorbents ... Carbonic Acid ... Gastric Acid Lowering Agents …
Matched Products: … TOP CALCIUM ... HEB Lime and Berry Antacid Chews ... TopCare Lime and Berry Antacid Chews …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …
Matched Description: … -403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak …

TSHA-101

Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … and has structural and functional characteristics similar to those of endogenous factor IX. ... Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Description: … Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase ... This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal ... When used as an ingredient in antiseptic and disinfectant products however, it is an active antimicrobial …
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... Whole Wipes ... ORA-SED JEL …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … BODY PRESCRIPTIONS Antibacterial Hand Wipes BERRY TWIST ... V3 Viral Defense Nano Silver Skin and Surface Protectant ... Antibacterial Hand Tropical Twist …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Gold and Sudsy ... GOJO Gold and Klean Antimicrobial Ltn Sp ... Highmark Professional Gold and Clean Antimicrobial Ltn Sp …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … plaque and reducing gingivitis. ... found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and ... In these products, it generally mediates an antiseptic activity and protective action against dental …
Matched Mixtures name: … GOLA ACTION ... GOLA ACTION ... GOLA ACTION …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Blood and Blood Forming Organs ... Antiinfectives and Antiseptics for Local Oral Treatment ... Blood Substitutes and Perfusion Solutions …
Matched Products: … CloSYS Silver Healthy Gums ... FARIN GOLA ... BOROCAINA GOLA …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched International brands: … Aceta Elixir ... Aceta Tablets …
Matched Description: … is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and ... tablets, injection, suppository, and other forms. …
Matched Mixtures name: … Sed-max ... Top Care Flu and Sore Throat ... CVS Health Non Drowsy Daytime Cold and Flu Relief And Nighttime Cold and Flu Relief Day and Night Twin …
Matched Categories: … Acetaminophen and Prodrugs ... tramadol and paracetamol ... oxycodone and paracetamol ... codeine and paracetamol ... hydrocodone and paracetamol …
Matched Products: … Little Remedies Infant Fever and Pain Reliever Natural Berry Natural Berry ... Berley and Jensen Pain Relief ... Help I Have a Headache …
Displaying drugs 26 - 50 of 2901 in total