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Displaying drugs 26 - 50 of 1335 in total

Miltefosine

Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease. It can be administered topically or orally and...
Approved
Investigational
Matched Synonyms: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … hexadecyl 2-(trimethylazaniumyl)ethyl phosphate …

Cipaglucosidase alfa

Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Synonyms: … Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate …
Matched Description: … mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues in Pompe ... Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent …

Sodium phosphate P 32

Approved
Matched Synonyms: … Sodium phosphate 32P ... Sodium phosphate (32P) ... Sodium phosphate P 32 …
Matched Name: … Sodium phosphate P 32 …
Matched Iupac: … disodium hydrogen (32P)phosphate …
Matched Categories: … sodium phosphate (32P) …

Pyridoxal phosphate

This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal 5-phosphate ... Pyridoxal 5'-phosphate ... Pyridoxal phosphate anhydrous …
Matched Name: … Pyridoxal phosphate …
Matched Description: … phosphate (pyridoxamine). ... During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine …
Matched Mixtures name: … Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin ... Levomefolate Calcium Pyridoxal-5 Phosphate Mecobalamin Algal ... Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Salts name: … Pyridoxal phosphate hydrate …
Matched Categories: … pyridoxal phosphate …

Tetracycline phosphate complex

Approved
Matched Synonyms: … Tetracycline phosphate complex …
Matched Name: … Tetracycline phosphate complex …

Polyestradiol phosphate

Polymeric phosphoric acid ester of estradiol.
Approved
Matched Synonyms: … Polyestradiol phosphate ... Estradiol phosphate polymer ... Poly(estradiol phosphate) …
Matched Name: … Polyestradiol phosphate …
Matched Categories: … polyestradiol phosphate …

Adenosine phosphate

Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Synonyms: … Adenosine phosphate ... Adenosine 5'-phosphate ... Phosphate d'adénosine …
Matched Name: … Adenosine phosphate …
Matched Description: … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its …

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Salts name: … Oseltamivir phosphate …
Matched Products: … Oseltamivir Phosphate ... Oseltamavir Phosphate ... Oseltamivir phosphate …

Histamine

A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Salts name: … Histamine phosphate …
Matched Categories: … histamine phosphate …
Matched Products: … Histamine Phosphate Injection USP Liq Sc ... Histamine Phosphate Injection USP, 1mg/ml …

Casein

Casein allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Calcium caseinate …

Chloroquine

Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Salts name: … Chloroquine phosphate …
Matched Products: … Chloroquine Phosphate ... Chloroquine phosphate ... CHLOROQUINE PHOSPHATE …

Disopyramide

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Salts name: … Disopyramide phosphate …
Matched Products: … Disopyramide Phosphate ... Disopyramide Phosphate ER …

Phosphoric acid

Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Approved
Matched Mixtures name: … Denti-care Acidulated Phosphate Fluoride …

Lanthanum carbonate

Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Description: … binding to dietary phosphate and preventing its absorption in the intestine. ... Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals ... It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by …
Matched Categories: … Phosphate Binder ... Phosphate-removing Agents …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium …
Matched Mixtures name: … Potassium Plus Vit B Complex ... C-apnto-B6 Vitamins W Magnesium Tab …
Matched Salts name: … Calcium pantothenate …
Matched Categories: … calcium pantothenate ... calcium pantothenate …
Matched Products: … Calcium Pantothenate Tab 250mg …

Fenoprofen

An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Salts name: … Fenoprofen calcium …
Matched Products: … Fenoprofen Calcium …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Mixtures name: … Bismuth subcitrate potassium, Metronidazole, Tetracycline hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Salts name: … Tetracycline phosphate …
Matched Categories: … Medications that reduce magnesium levels …
Matched Products: … TETRACIN (PHOSPHATE BUFFERED) CAPSULES. ... TETRACYCLINE HCL ( PHOSPHATE BUFFERED )250 CAPSULES …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Description: … Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal …
Matched Categories: … Phosphate Binder ... Phosphate-removing Agents ... Phosphate Chelating Activity …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Mixtures name: … Calcium Magnesium Plus Vitamin D Liquid ... Calcium Magnesium Avec Vitamine D Et Zinc ... Calcium and Magnesium Citrate With Vitamin D …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus …
Matched Mixtures name: … Calcium & Magnesium With Potassium, Zinc, Manganese & Vitamin D ... Calcium & Magnesium Citrate Plus D With Manganese, Potassium & Zinc ... Calcium & Magnesium Citrate Plus D With Manganese, Potassium & Zinc …
Matched Categories: … Calcium-Regulating Hormones and Agents ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential ... risedronic acid, calcium and colecalciferol, sequential …

Alfacalcidol

Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … [A234044] It plays an essential function in calcium homeostasis and bone metabolism. …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Categories: … Calcium Homeostasis ... Calcium-sensing Receptor Agonist ... Increased Calcium-sensing Receptor Sensitivity …

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... influx through voltage-gated T-type calcium channels. …
Matched Categories: … Calcium Channel Blockers ... ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Beta blocking agents and calcium channel blockers …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth ... Nimodipine is a 1,4-dihydropyridine calcium channel blocker. ... It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels …
Matched Categories: … Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers (Dihydropyridine) ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Displaying drugs 26 - 50 of 1335 in total