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Displaying drugs 51 - 75 of 13074 in total

Zanamivir

A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid ... 6-carboxylic acid …
Matched Iupac: … -6-carboxylic acid ... (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Products: … RELENZA ROTADISK, 5 ADET ... RELENZA ROTADISK 5 mg/dose …

Hexaminolevulinate

Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride ... 4-Hexyloxycarbonyl-2-oxobutylammoniumchloride ... Hexyl 5-amino-4-oxopentanoate hydrochloride …
Matched Iupac: … hexyl 5-amino-4-oxopentanoate …
Matched Salts cas: … 140898-91-5 …

Edoxudine

Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2'-Deoxy-5-ethyluridine ... 5-Ethyl-2'-deoxyuridine …
Matched Iupac: … 5-ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. …

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … azabicyclo[3.2.0]heptane-2-carboxylic acid ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid ... (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Iupac: … [3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Salts cas: … 23736-58-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ./5 มล.) ... OXACIL GRANULES 125 MG/ 5 ML ... CLOXACILLA POWDER FOR SYRUP 125 MG / 5 ML …

Cefotiam

One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … ]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl …
Matched Iupac: … -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Etomidate

Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Matched Synonyms: … (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester ... (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester ... 3-((R)-1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ethyl ester …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …
Matched Products: … HYPNOMIDATE 2 MG /10 ML AMPUL, 5 ADET ... ETOMIDATO 2 MG/ML ... TROYMIDATE 2 MG/ ML EMULSIÓN INYECTABLE …

Thymol

A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Approved
Matched Synonyms: … 2-isopropyl-5-methylphenol ... 5-Methyl-2-(1-Methylethyl)Phenol …
Matched Iupac: … 5-methyl-2-(propan-2-yl)phenol …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … (±)-2-(p-isobutylphenyl)propionic acid ... 2-(4-isobutylphenyl)propanoic acid ... (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML ... Adventure Medical Kits 1-2 Person First Aid …
Matched Categories: … Arylpropionic acid NSAIDS ... COX-2 Inhibitors ... Non COX-2 selective NSAIDS …
Matched Products: … มาบูโปรเฟน-2 ... SMADOL SUSPENSION 2% ... Winofen Suspension 2%w/v …

Cefuroxime

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … [4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Salts cas: … 56238-63-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TOZ ICEREN FLAKON, 1 ADET+2 ML COZUCU AMPUL ... ENJEKSİYONLUK TOZ İÇEREN FLAKON, 2 ML 1 AMPUL, FLAKON, 1 ADET ... ZINNAT SUSPENSION 250 MG/5 ML. …

Zolmitriptan

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 2.5 MG FİLM TABLET, 2 ADET ... Zomig 5 mg Nasenspray …

Cefazolin

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Synonyms: … 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]- …
Matched Iupac: … ]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[2-(1H-1,2,3,4-tetrazol-1-yl)acetamido …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Kefzol 2 g - Trockensubstanz zur Infusionsbereitung ... Cefazolin Sandoz 2 g - Pulver zur Herstellung einer Infusionslösung ... Cefazolin Sandoz 2 g - Pulver zur Herstellung einer Injektionslösung …

Suprofen

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... p-2-thenoylhydratropic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …

Nitrofural

Nitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections. Nitrofural has also been administered orally in the treatment of trypanosomiasis. Except for topical drug products formulated for dermatologic application, the FDA withdrew its approval...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … 5-Nitro-2-furaldehyde semicarbazone …
Matched Iupac: … [(E)-[(5-nitrofuran-2-yl)methylidene]amino]urea …
Matched Products: … NITROCIN % 2 MERHEM, 56 G ... FURAZOL OFTALMİK LİKİD, 5 ML …

Carindacillin

Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid …
Matched Iupac: … -azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-mercaptoethanesulfonic acid ... 2-mercaptoethanesulphonic acid ... β-mercaptoethanesulfonic acid …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …

Cephalexin

Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... acid ... 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... acid …
Matched Salts cas: … 23325-78-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … CELEXIN GRANULES 125 mg/5 ml ... สปอริดิน 125 มิลลิกรัม/5 มิลลิลิตร ... CEFALEXINA POLVO PARA SUSPENSION 5% …

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl ... 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl ... )-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)- …
Matched Iupac: … 2-({3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen ... -2-yl}formamido)-N-(2,2,2-trifluoroethyl)acetamide …

Dinoprostone

Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid ... (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Products: … PROSTIN E 2 …

1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ... l-Alpha-1-palmitoyl-2-oleoylglycerophosphoglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester ... 2-Diethylaminoethyl p-aminobenzoate …
Matched Iupac: … 2-(diethylamino)ethyl 4-aminobenzoate …
Matched Categories: … Esters of Aminobenzoic Acid …
Matched Products: … NTCAIN 50 MG/5 ML IM AMPUL , 10 ADET ... NTCAIN 50 MG/5 ML IM AMPUL , 50 ADET ... NTCAIN 50 MG/5 ML IM AMPUL , 100 ADET …

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide ... 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide ... 3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …
Matched Products: … SUTRIP 100 MG TABLET, 2 ADET ... İMİGRAN 50 MG FILM KAPLI TABLET, 2 ADET ... İMİGRAN 100 MG FILM KAPLI TABLET, 2 ADET …

Glyburide

Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea ... 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide ... 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea …
Matched Iupac: … 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide …
Matched Mixtures name: … Tablets 5/500mg ... SIL-NORBORAL ® 5/500 MG ... GLUCOVANCE TABLET 500 mg/5 mg …
Matched Products: … GLIDANIL 5 ... GLUCONIN 5 ... ยูนิล - 5 …

Tegafur

Tegafur (INN, BAN, USAN) is a prodrug of DB00544 (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with DB09257 and DB03209, or along with...
Approved
Investigational
Matched Synonyms: … 1-(2-Tetrahydrofuryl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … high concentrations of 5-FU at a lower dose of tegafur [L933]. ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU …

Lumacaftor

Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic ... acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... from baseline with more than 70% of patients failing to achieve an absolute improvement of at least 5% ... [A18395] The next most common mutation, G551D, affecting 4-5% of CF patients worldwide, is characterized …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Methylchloroisothiazolinone

Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Synonyms: … 5-Chloro-2-methyl-3(2H)-isothiazolone ... 4-Isothiazolin-3-one, 5-chloro-2-methyl- ... 5-Chloro-N-methylisothiazolin-3-one …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Displaying drugs 51 - 75 of 13074 in total