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Displaying drugs 1626 - 1650 of 1845 in total

Technetium Tc-99m tilmanocept

Technetium Tc-99m tilmanocept is a radiopharmaceutical diagnostic imaging agent approved by the U.S. Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging. It is a macromolecule consisting of multiple units of diethylenetriaminepentaacetic acid (DTPA) and mannose, each covalently attached to a 10 kDa...
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging ... DTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label]. ... may be used to predict tumour staging and metastasis [A32170]. …
Matched Products: … Kit for the preparation of Lymphoseek (technetium Tc 99m tilmanocept) …

3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE

Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
Matched Iupac: … (2S,3R)-3-formyl-N,2-dihydroxy-5-methylhexanamide …

Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)

Approved
Matched Products: … Pandemic Influenza Vaccine H5N1 Baxter Suspension for Injection …

Capromab pendetide

Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Matched Description: … specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and ... When linked to pendetide, capromab is used as a chelating agent for the radionuclide [Indium In-111] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents …
Matched Products: … ProstaScint Kit for the Preparation of Indium In 111 Capromab Pendetide …

Galsulfase

Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... enzyme activity and is conserved in all members of the sulfatase enzyme family. ... sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Matched Products: … Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1ml …

Antithrombin III human

A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Anbinex Powder For Injection 500 I.U. ... Anbinex Powder For Injection 1000 I.U. …

Brolucizumab

Brolucizumab, also known as RTH258 or ESBA1008, is a monoclonal antibody indicated to treat neovascular age related macular degeneration. Brolucizumab was granted FDA approval in October 2019.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Pagenax 120mg/ml Solution For Injection …

Edaravone

Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Description: … Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and ... [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and ... Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. …
Matched Products: … RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mL …

Lutropin alfa

Lutropin alfa is a recombinant human luteinizing hormone produced in yeast with 2 subunits, alpha = 92 residues, beta = 121 residues. It is a heterodimeric glycoprotein made up of monomeric units. Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for use in...
Approved
Matched Description: … Lutropin alfa was the first and only recombinant human form of luteinizing hormone (LH) developed for ... biological activity of endogenous LH; an acute rise of LH, or LH surge, in females triggers ovulation and …
Matched Mixtures name: … Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Sex Hormones and Modulators of the Genital System …
Matched Products: … LUVERIS FOR INJECTION 75 iu/vial (Revised formula) …

Human cytomegalovirus immune globulin

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … antibody for cytomegalovirus (CMV). ... , urine, cervical and vaginal excretions, semen, breast milk and blood [L2228]. ... CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …

Pyrophosphoric acid

Approved
Experimental
Matched Mixtures name: … Phosphotec …
Matched Salts name: … Sodium pyrophosphate ... Sodium pyrophosphate decahydrate …
Matched Categories: … Phosphate salts …
Matched Products: … TECHNESCAN PYP, KIT FOR RADIOPHARMACEUTICAL PREPARATION, 20MG/VIAL …

Rabies virus inactivated antigen, A

Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies virus.
Approved
Investigational
Matched Description: … Rabies virus inactivated antigen, A is an inactivated virus vacine for the intramuscular injection. ... It is an active immunization against rabies that can be administered pre- or post-exposure to the rabies …
Matched Categories: … Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … Rabipur Lyophilised Powder for Injection …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …

Methylnaltrexone

Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It is also used for high-conditioning before hematopoietic stem cell transplant. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Matched Mixtures name: … Melphalan for Injection ... Melphalan for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan for Injection ... ALKERAN FOR INJECTION 50 mg/vial …

Palonosetron

Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … and treatment of chemotherapy-induced nausea and vomiting (CINV). ... It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that ... Food and Drug Administration. …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … Solution for Injection 50mcg/ml ... ALOXI Solution for Injection 50mcg/ml ... PALSET (Palonosetron Hydrochloride Solution for Injection 0.05 mg/ml, 5 ml vial) …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …

Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … BETAFERON FOR INJECTION 0.25 mg/ml …

Tonabacase

Investigational
Matched Synonyms: … Bacteriolysin sal-1 (staphylococcus phage sap-1) ... aureus phage 1 (sap-1)-derived soluble endolysin (staphylococcus aureus phage lysin-1, bacteriolysin sal …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … CIN-QUIN …
Matched Description: … [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. ... Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. …
Matched Categories: … Quinine and stereoisomer ... Metabolic Side Effects of Drugs and Substances ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Quinidine Gluconate for Inj 80mg/ml USP …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … Certain population subgroups in these areas, however, are at high risk (see Indications and Clinical ... There is no specific treatment for hepatitis. ... The hepatitis B virus induces a severe form of viral hepatitis. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinfectives for Systemic Use ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BAKAMSİLİN FORT 800 MG FİLM TABLET, 10 ADET …

Olive oil

Oil extracted from olives . Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label].
Approved
Matched Description: … Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic. ... Used as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products …
Matched Mixtures name: … SmofKabiven, Emulsion for Infusion ... OLIMEL N7E, emulsion for infusion ... OLIMEL N9E, emulsion for infusion …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Intensive Treatment Bodyoil for Mommy To Be All Skin …

Mebrofenin

Approved
Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Kit for the Preparation of Technetium Tc 99m Mebrofenin …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …
Displaying drugs 1626 - 1650 of 1845 in total