Displaying drugs 176 - 200 of 2597 in total
Bimatoprost
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. ... Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Cardiovascular Agents ... Antihypertensive Agents …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Description: … Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which ... in 2008, as eyelash growth became a desirable adverse effect for patients using this drug. ... Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Cardiovascular Agents ... Antihypertensive Agents …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Enprofylline
Enprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Long-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels.
Approved
Experimental
Matched Synonyms: … 3-n-propylxanthine ... 3-propylxanthine ... 3-Propyl-3,7-dihydro-purine-2,6-dione …
Matched Iupac: … 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Enprofylline is a derivative of theophylline which shares bronchodilator properties. ... insufficiency, sickle cell disease, and diabetic neuropathy. ... Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular …
Matched Categories: … Autonomic Agents ... Anti-Asthmatic Agents ... Purinergic Agents ... Bronchodilator Agents ... Neurotransmitter Agents …
Matched Iupac: … 3-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Enprofylline is a derivative of theophylline which shares bronchodilator properties. ... insufficiency, sickle cell disease, and diabetic neuropathy. ... Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular …
Matched Categories: … Autonomic Agents ... Anti-Asthmatic Agents ... Purinergic Agents ... Bronchodilator Agents ... Neurotransmitter Agents …
Flurandrenolide
A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)
Approved
Matched Description: … It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive ... A corticosteroid used topically in the treatment of various skin disorders. …
Matched Categories: … Corticosteroids, Potent (Group III) ... Anti-Inflammatory Agents ... Immunosuppressive Agents ... fludroxycortide and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Corticosteroids, Potent (Group III) ... Anti-Inflammatory Agents ... Immunosuppressive Agents ... fludroxycortide and antibiotics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Triamcinolone
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more...
Approved
Vet approved
Matched International brands: … Omcilon-A …
Matched Iupac: … trihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and ... [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957 ... or first line as a topical treatment of corticosteroid responsive dermatoses. …
Matched Mixtures name: … Pro-C-Dure 3 Kit ... Mlp A-2 ... Mlp A-1 …
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Inflammatory Agents ... Agents Causing Muscle Toxicity ... Agents to Treat Airway Disease ... Immunosuppressive Agents …
Matched Products: … แอคซิน 3 ครีม ... Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy …
Matched Iupac: … trihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and ... [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957 ... or first line as a topical treatment of corticosteroid responsive dermatoses. …
Matched Mixtures name: … Pro-C-Dure 3 Kit ... Mlp A-2 ... Mlp A-1 …
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Inflammatory Agents ... Agents Causing Muscle Toxicity ... Agents to Treat Airway Disease ... Immunosuppressive Agents …
Matched Products: … แอคซิน 3 ครีม ... Up and Up Nasal Allergy ... Foster and Thrive 24 Hour Nasal Allergy …
Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched International brands: … OraDisc A …
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. ... Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Anti-Allergic Agents ... Alimentary Tract and Metabolism …
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. ... Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Anti-Allergic Agents ... Alimentary Tract and Metabolism …
Latanoprost
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Synonyms: … isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate ... propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate …
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse ... Another benefit latanoprost is that it can be administered once a day.[A184490] ... Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … Antihypertensive Agents ... Compounds used in a research, industrial, or household setting ... latanoprost and netarsudil ... Antiglaucoma Preparations and Miotics …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate …
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse ... Another benefit latanoprost is that it can be administered once a day.[A184490] ... Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … Antihypertensive Agents ... Compounds used in a research, industrial, or household setting ... latanoprost and netarsudil ... Antiglaucoma Preparations and Miotics …
Dextropropoxyphene
Dextropropoxyphene is an opioid analgesic manufactured by Eli Lilly and Company. It is used in the symptomatic treatment of mild pain. It displays antitussive and local anaesthetic actions. Due to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe...
Approved
Illicit
Investigational
Withdrawn
Matched Iupac: … (2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl propanoate …
Matched Description: … The levo-isomer appears to exhibit a very limited antitussive effect. ... It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen …
Matched Categories: … Sensory System Agents ... Central Nervous System Agents ... Agents that reduce seizure threshold ... Peripheral Nervous System Agents …
Matched Description: … The levo-isomer appears to exhibit a very limited antitussive effect. ... It displays antitussive and local anaesthetic actions. ... been withdrawn from the market in Europe and the United States. …
Matched Mixtures name: … Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen ... Propoxyphene and Acetaminophen …
Matched Categories: … Sensory System Agents ... Central Nervous System Agents ... Agents that reduce seizure threshold ... Peripheral Nervous System Agents …
Cholecalciferol
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … Vitamin D-3 ... (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol ... (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene …
Matched Description: … C22 and C23 and has an additional methyl group at C24 [L5689]. ... levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation ... Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there …
Matched Mixtures name: … Liquid Calcium Mg Phosphorus and Vit.d-3 ... VITAMINS A, C, D and FLUORIDE ... Vitamins A, C, D and Fluoride Drops …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Bone Density Conservation Agents ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Diet, Food, and Nutrition …
Matched Products: … Amerix Vitamin D 3 ... Vi - De 3 - Tropfen ... GNC Vitamin D-3 400 …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene …
Matched Description: … C22 and C23 and has an additional methyl group at C24 [L5689]. ... levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation ... Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there …
Matched Mixtures name: … Liquid Calcium Mg Phosphorus and Vit.d-3 ... VITAMINS A, C, D and FLUORIDE ... Vitamins A, C, D and Fluoride Drops …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Bone Density Conservation Agents ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Diet, Food, and Nutrition …
Matched Products: … Amerix Vitamin D 3 ... Vi - De 3 - Tropfen ... GNC Vitamin D-3 400 …
Felodipine
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers ... ramipril and felodipine ... metoprolol and felodipine ... ACE Inhibitors and Calcium Channel Blockers …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. ... In addition to binding to L-type calcium channels, felodipine binds to a number of calcium-binding proteins ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers ... ramipril and felodipine ... metoprolol and felodipine ... ACE Inhibitors and Calcium Channel Blockers …
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene ... (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2 ... (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene- …
Matched Iupac: … (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo …
Matched Description: … [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative ... and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam ... Anti-Bacterial Agents ... Neurotoxic agents ... Anti-Infective Agents …
Matched Iupac: … (5R,6S)-3-({2-[(E)-(aminomethylidene)amino]ethyl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo …
Matched Description: … [A15389] Imipenem is commonly used in combination with [cilastatin] and is now available in a triple-drug ... Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative ... and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam ... Anti-Bacterial Agents ... Neurotoxic agents ... Anti-Infective Agents …
Paromomycin
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Synonyms: … Monomycin A ... ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino …
Matched Categories: … Alimentary Tract and Metabolism ... Nephrotoxic agents ... Anti-Bacterial Agents ... Anti-Infective Agents ... Antiparasitic Agents …
Matched Iupac: … -6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl ... (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino …
Matched Categories: … Alimentary Tract and Metabolism ... Nephrotoxic agents ... Anti-Bacterial Agents ... Anti-Infective Agents ... Antiparasitic Agents …
Dicoumarol
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … bis(4-hydroxycoumarin-3-yl)methane ... di-(4-hydroxy-3-coumarinyl)methane …
Matched Iupac: … 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one …
Matched Categories: … Blood and Blood Forming Organs ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Hematologic Agents ... Uncoupling Agents ... Fibrinolytic Agents …
Matched Iupac: … 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one …
Matched Categories: … Blood and Blood Forming Organs ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Hematologic Agents ... Uncoupling Agents ... Fibrinolytic Agents …
Alfacalcidol
Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Description: … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue ... The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback ... malabsorptive rickets and osteomalacia, vitamin D-dependent rickets and osteomalacia, and hypophosphataemic …
Matched Categories: … Bone Density Conservation Agents ... Vitamin D and Analogues ... Alimentary Tract and Metabolism ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Categories: … Bone Density Conservation Agents ... Vitamin D and Analogues ... Alimentary Tract and Metabolism ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization …
Setmelanotide
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Iupac: … 10-{3-[(diaminomethylidene)amino]propyl}-16-[(1H-imidazol-5-yl)methyl]-7-[(1H-indol-3-yl)methyl]-19-methyl ... (4R,7S,10S,13R,16S,19R,22R)-13-benzyl-22-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]- …
Matched Description: … [A224449] Imcivree was granted EMA orphan designation on November 19, 2018 [L24559] and FDA approval ... agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and …
Matched Categories: … Anti-Obesity Agents ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … [A224449] Imcivree was granted EMA orphan designation on November 19, 2018 [L24559] and FDA approval ... agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and …
Matched Categories: … Anti-Obesity Agents ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Estetrol
Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Matched Iupac: … (1R,2R,3R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … [L33184] On April 15 2021, Mayne Pharma Group Limited and Mithra Pharmaceuticals were granted FDA ... from a plant source and used for contraception. ... The combination of drospirenone and estetrol offers a new choice with a favourable safety profile for …
Matched Salts cas: … 2055649-81-3 …
Matched Categories: … drospirenone and estetrol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … [L33184] On April 15 2021, Mayne Pharma Group Limited and Mithra Pharmaceuticals were granted FDA ... from a plant source and used for contraception. ... The combination of drospirenone and estetrol offers a new choice with a favourable safety profile for …
Matched Salts cas: … 2055649-81-3 …
Matched Categories: … drospirenone and estetrol ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Liotrix
Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Iupac: … disodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate (2S)-2-amino-3-[ ... 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate …
Matched Description: … a 4 to 1 ratio by weight. ... Liotrix is a synthetically derived thyroid hormone replacement preparation. ... and combination hormone replacement therapy generally offers no therapeutic advantage. …
Matched Categories: … Agents used to treat hypothyroidism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … a 4 to 1 ratio by weight. ... Liotrix is a synthetically derived thyroid hormone replacement preparation. ... and combination hormone replacement therapy generally offers no therapeutic advantage. …
Matched Categories: … Agents used to treat hypothyroidism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pindolol
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol ... 4-(2-hydroxy-3-isopropylaminopropoxy)-indole ... 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … [A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] ... Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... [L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation …
Matched Categories: … Antidepressive Agents ... pindolol and other diuretics ... Adrenergic Agents ... Serotonin Agents ... Hypotensive Agents …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … [A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] ... Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. ... [L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation …
Matched Categories: … Antidepressive Agents ... pindolol and other diuretics ... Adrenergic Agents ... Serotonin Agents ... Hypotensive Agents …
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Sunscreen Agents …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916]. …
Matched Categories: … Sunscreen Agents …
Ceforanide
Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … 7-[O-(aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic ... (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl] ... 7β-[2-(aminomethyl)phenyl]acetamido-3-{[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl-3,4-didehydrocepham …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. ... Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ... ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …
Matched Iupac: … (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …
Matched Description: … It has a longer elimination half-life than any currently available cephalosporin. ... Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to ... ceforanide, as are most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine …
Matched Description: … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently ... for the treatment of intractable hiccups as it is a potent antiemetic. ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain …
Matched Categories: … Autonomic Agents ... Antipsychotic Agents ... Anti-Dyskinesia Agents ... Dopamine Agents ... Neurotoxic agents …
Matched Products: … Truemed Group LLC ... Haldol Decanoat 150 mg/3 ml Injektionslösung ... NORODOL DEKANOAT 150 MG/3 ML IM ENJ. ICIN COZELTI, 1 AMPUL …
Matched Description: … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently ... for the treatment of intractable hiccups as it is a potent antiemetic. ... [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain …
Matched Categories: … Autonomic Agents ... Antipsychotic Agents ... Anti-Dyskinesia Agents ... Dopamine Agents ... Neurotoxic agents …
Matched Products: … Truemed Group LLC ... Haldol Decanoat 150 mg/3 ml Injektionslösung ... NORODOL DEKANOAT 150 MG/3 ML IM ENJ. ICIN COZELTI, 1 AMPUL …
Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate ... [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse ... the eye, ear, nose, and throat. …
Matched Categories: … Analgesics and Anesthetics ... Dopamine Agents ... Anticholinergic Agents ... Cardiovascular Agents ... Agents producing tachycardia …
Matched Iupac: … methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse ... the eye, ear, nose, and throat. …
Matched Categories: … Analgesics and Anesthetics ... Dopamine Agents ... Anticholinergic Agents ... Cardiovascular Agents ... Agents producing tachycardia …
Clofarabine
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … Cl-F-Ara-A ... (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... OCT2 Substrates with a Narrow Therapeutic Index ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index ... Antineoplastic Agents …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. ... Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. ... Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... OCT2 Substrates with a Narrow Therapeutic Index ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index ... Antineoplastic Agents …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … A barbiturate that is administered intravenously for the induction of general anesthesia or for the production ... It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. …
Matched Categories: … Hypnotics and Sedatives ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... GABA Agents ... Anticholinergic Agents ... Hypotensive Agents …
Matched Categories: … Hypnotics and Sedatives ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... GABA Agents ... Anticholinergic Agents ... Hypotensive Agents …
Vernakalant
Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Synonyms: … (3R)-1-((1R,2R)-2-(2-(3,4-dimethoxyphenyl)ethoxy)cyclohexyl)pyrrolidin-3-ol …
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol …
Matched Description: … Intravenous formulation was approved in Europe in September 2010 as Brinavess and in Canada in April …
Matched Categories: … Antiarrhythmic agents ... QTc Prolonging Agents ... Potential QTc-Prolonging Agents …
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol …
Matched Description: … Intravenous formulation was approved in Europe in September 2010 as Brinavess and in Canada in April …
Matched Categories: … Antiarrhythmic agents ... QTc Prolonging Agents ... Potential QTc-Prolonging Agents …
Ertugliflozin
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Synonyms: … 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose ... (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane ... β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …
Matched Description: … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes …
Matched Categories: … Blood Glucose Lowering Agents ... Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …
Matched Description: … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes …
Matched Categories: … Blood Glucose Lowering Agents ... Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin …
Displaying drugs 176 - 200 of 2597 in total