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Polysorbate 20

Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical products. It is composed of 20 repeated units of polyethylene glycol via ethoxylation. Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer in labratory assays and industrial applications....
Approved
Matched Synonyms: … Polysorbate 20 …
Matched Name: … Polysorbate 20 …
Matched Description: … Polysorbate 20 is a polysorbate-type nonionic surfactant used in many commercial, household and pharmaceutical ... Polysorbate 20 is a wetting agent in food products, as well as washing agent, stabilizer and solubilizer ... It is composed of 20 repeated units of polyethylene glycol via ethoxylation. …

Streptococcus pneumoniae type 20 capsular polysaccharide antigen

Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 20 of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Synonyms: … pneumococcal capsular polysaccharide type 20 vaccine …
Matched Name: … Streptococcus pneumoniae type 20 capsular polysaccharide antigen …
Matched Description: … intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and ... capsular polysaccharides from the invasive pneumococcal type 20 of *Streptococcus pneumoniae*. ... Streptococcus pneumoniae type 20 capsular polysaccharide antigen is a vaccine that contains highly purified …

Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta-1b ... Interferon-beta-1b ... Interferon beta 1b (recombinant) …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Interferon-beta ... interferon beta-1b ... Amino Acids, Peptides, and Proteins ... Recombinant Human Interferon beta ... Antineoplastic and Immunomodulating Agents …

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …

VidPrevtyn Beta

VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 cells of the fall...
Approved
Investigational
Matched Name: … VidPrevtyn Beta …
Matched Description: … [A245829,L49696] In October 2022, VidPrevtyn Beta was approved in the European Union for use as a ... (GSK) and Sanofi Pasteur. ... VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline …

Beta vulgaris pollen

Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Name: … Beta vulgaris pollen …
Matched Description: … Beta vulgaris pollen is the pollen of the Beta vulgaris plant. ... Beta vulgaris pollen is mainly used in allergenic testing. …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Name: … Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine …
Matched Description: … , marketed as MENVEO, was first approved by the FDA in 2010. ... Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used ... meningococcal disease, which is caused by bacteria _Neisseria meningitidis_ entering the bloodstream and …

Polysorbate 80

Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it acts as an emulsifier, a solubilizer in many foods, including bread, cake mix, salad dressing, shortening oil and...
Approved
Matched Synonyms: … polyoxyethylene-sorbitan-20 mono-oleate …
Matched Description: … It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops. ... , and water-containing small amounts of salts, and is included in several vaccines licensed in the USA ... (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and …
Matched Mixtures name: … REFRESH Optive Mega-3 ... REFRESH Optive Mega-3 …

Vayarin

Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Vayarin contains _Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic ... acid), and docosahexaenoic acid (DHA) [L1500, L1510]. ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … (CG- .BETA.)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM ... 118-145-GONADOTROPIN, CHORIONIC (HUMAN .BETA. ... (CG-.BETA.)-(118-145)- PEPTIDE (220-247 …
Matched Description: … generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta ... [L39060] In June 2023, the FDA approved the use of somatrogon also for the treatment of pediatric growth ... [L39362] In October 2021, Health Canada approved somatrogon under the market name NGENLA as the long-term …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …

Tilactase

Tilactase is a beta-D-galactosidase obtained from Aspergillus oryzae. It is produced as a chewable tablet that has to be taken before the consumption of a lactose-containing meal. The beta-D-galactosidase us a large monomeric multi-domain enzyme of 985 residues that presents a catalytic (alpha/beta)8-barrel domain. It is considered by the WHO...
Approved
Experimental
Matched Synonyms: … beta-Galactosidase ... beta-D-Galactosidase …
Matched Description: … a catalytic (alpha/beta)8-barrel domain. ... Tilactase is a beta-D-galactosidase obtained from _Aspergillus oryzae_. ... [A27172] The beta-D-galactosidase us a large monomeric multi-domain enzyme of 985 residues that presents …
Matched Categories: … beta-Galactosidase ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(4-Chlorophenyl)gaba …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Baclofen-20 ... BACLOFEN 10 MG/ 20 ML ... BACLOFEN 40 MG / 20 ML …

Follitropin

Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … FSH-beta ... Folitropina beta ... Follitrophin beta …
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... Numerous physio-chemical tests and bioassays indicate that follitropin beta and follitropin alpha are ... The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn …
Matched Mixtures name: … PERGOVERIS 150 IU/75 IU ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 3 ADET ... MENOGON 75 IU Powder and Solvent for solution for Injection ... Pergoveris 150IU/75IU powder and solvent for solution for injection …
Matched Categories: … follitropin beta ... Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Artemotil

Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.
Approved
Matched Synonyms: … beta-Arteether ... beta-Dihydroartemisinin ethyl ether …
Matched Description: … Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting ... schizonticide specifically indicated for the treatment of chloroquine-resistant _Plasmodium falciparum_ malaria and …
Matched Categories: … Artemisinin and derivatives ... Antiparasitic Products, Insecticides and Repellents …

Nicoboxil

Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option. Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately...
Approved
Investigational
Matched Synonyms: … beta-Butoxyethyl nicotinate …
Matched Iupac: … 2-butoxyethyl pyridine-3-carboxylate …
Matched Description: … of Europe and Asia, like Germany and Australia [F11, F16]. ... investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and ... topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and …

Bronopol

Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Synonyms: … beta-Bromo-beta-nitrotrimethyleneglycol …
Matched Description: … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, ... registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives …
Matched Categories: … Indicators and Reagents …

Sarocladium strictum

Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …

Adenosine

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … beta-D-Adenosine ... 9-beta-D-Ribofuranosidoadenine ... 6-Amino-9-beta-D-ribofuranosyl-9H-purine …
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and …
Matched Mixtures name: … Plalab Placenta R-20 ... Propolis 20 BB Cream ... Oattbe Syn Bio beta Glucans Brightening Calming …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Oattbe Syn Bio beta Glucans Serum ... misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment …

Arbutin

Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … beta-Arbutin ... 4-Hydroxyphenyl-beta-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... and [DB09526] [F43]. ... It is found in foods, over-the-counter drugs, and herbal dietary supplements [F43]. …
Matched Mixtures name: … Propolis 20 BB Cream …

Lactulose

Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Iupac: … (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl …
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … in patients with genotype 2 and 3 [A19626]. ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... ribavirin in the combination therapies depend on individual patient's profile, for example if HCV genotype 3 …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …

Vidarabine

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
Approved
Investigational
Matched Synonyms: … 9-beta-D-arabinofuranosyl-adenine ... 9-beta-D-Arabinofuranosyladenine ... 9-beta-D-arabinofuranosyl-9H-purin-6-amine …
Matched Description: … viruses, the vaccinia VIRUS and varicella zoster virus. ... It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures ... and significant antiviral activity against infections caused by a variety of viruses such as the herpes …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Talquetamab

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY; BISPECIFIC …
Matched Description: … [L47775] Talquetamab was fully approved by the EMA on August 22, 2023. ... arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cysteamine

Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … beta-aminoethanethiol ... beta-Mercaptoethylamine …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism …
Displaying drugs 1 - 25 of 15248 in total