Prescribing azithromycin.

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McMullan BJ, Mostaghim M

Prescribing azithromycin.

Aust Prescr. 2015 Jun;38(3):87-9. Epub 2015 Jun 1.

PubMed ID

26648627 [ View in PubMed

]

Abstract

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and excellent tissue penetration. It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used in preference to other macrolides for some sexually transmitted and enteric infections. Azithromycin has additional immunomodulatory effects and has been used in chronic respiratory inflammatory diseases for this purpose. Potential major adverse effects include cardiovascular arrhythmias and hearing loss. Macrolide resistance is also a problem, as are interactions with commonly prescribed drugs.

DrugBank Data that Cites this Article

Drugs

Azithromycin

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Azithromycin	P-glycoprotein 1	Protein	Humans	Unknown	Substrate Inhibitor	Details

Drug Interactions

Drugs	Interaction
Integrate drug-drug interactions in your software
Digoxin Azithromycin	The serum concentration of Digoxin can be increased when it is combined with Azithromycin.
Digoxin Roxithromycin	The serum concentration of Digoxin can be increased when it is combined with Roxithromycin.
Digoxin Sirolimus	The serum concentration of Digoxin can be increased when it is combined with Sirolimus.
Digoxin Dirithromycin	The serum concentration of Digoxin can be increased when it is combined with Dirithromycin.
Digoxin Telithromycin	The serum concentration of Digoxin can be increased when it is combined with Telithromycin.