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Identification
NamePrednisone
Accession NumberDB00635  (APRD00340)
TypeSmall Molecule
GroupsApproved
Description

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. [PubChem]

Structure
Thumb
Synonyms
1,2-Dehydrocortisone
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
Dehydrocortisone
Prednisona
Prednisonum
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Alti-prednisone Tab 5mgtablet5 mgoralAltimed Pharma Inc.1984-12-311998-08-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Deltasone 50mgtablet50 mgoralPharmacia & Upjohn Inc1972-12-312000-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Deltasone 5mgtablet5 mgoralPharmacia & Upjohn Inc1972-12-312000-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Jaa Prednisone Tab 1mg USPtablet1.0 mgoralJaapharm Canada Inc.1993-05-15Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Jaa Prednisone Tab 50mg USPtablet50 mgoralJaapharm Canada Inc.1993-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Jaa Prednisone Tab 5mg USPtablet5 mgoralJaapharm Canada Inc.1993-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nu-prednisonetablet5 mgoralNu Pharm IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nu-prednisonetablet1 mgoralNu Pharm IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nu-prednisonetablet50 mgoralNu Pharm IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Prednisone 50 Tab 50mgtablet50 mgoralPro Doc Limitee1994-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Prednisone Tab 5mgtablet5 mgEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Prednisone Tab 5mgtablet5 mgoralPro Doc Limitee1959-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Rayostablet, delayed release1 mg/1oralHorizon Pharma Inc.2012-07-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Rayostablet, delayed release5 mg/1oralHorizon Pharma Inc.2012-07-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Rayostablet, delayed release2 mg/1oralHorizon Pharma Inc.2012-07-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Teva-prednisonetablet50 mgoralTeva Canada Limited1972-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-prednisonetablet5 mgoralTeva Canada Limited1967-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Winpred Tab 1mgtablet1 mgoralAa Pharma Inc1978-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Winpred Tab 5mgtablet5 mgoralValeant Canada Lp Valeant Canada S.E.C.1985-12-312013-07-30Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo Prednisone Tab 1mg USPtablet1 mgoralApotex Inc1984-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Apo Prednisone Tab 50mgtablet50 mgoralApotex Inc1982-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Apo Prednisone Tab 5mgtablet5 mgoralApotex Inc1982-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Deltasonetablet20 mg/20mgoralOculus Innovative Sciences2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Perrigo Prednisonetablet5 mg/1oralPerrigo Pharmaceuticals Company2006-05-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Perrigo Prednisonetablet10 mg/1oralPerrigo Pharmaceuticals Company2006-05-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Perrigo Prednisonetablet20 mg/1oralPerrigo Pharmaceuticals Company2006-10-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralRoxane Laboratories, Inc.2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPreferred Pharmaceuticals, Inc.2014-03-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-05-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralSTAT Rx USA LLC2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralA S Medication Solutions Llc1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralCardinal Health2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralProficient Rx LP2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralDispensing Solutions, Inc.2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralAmerican Health Packaging2015-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralBlenheim Pharmacal, Inc.2013-11-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralWatson Laboratories, Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralSafecor Health, LLC2014-09-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralH.J. Harkins Company, Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralUnit Dose Services1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralRebel Distributors Corp2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralSTAT Rx USA LLC1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralPhysicians Total Care, Inc.2009-12-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralClinical Solutions Wholesale2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralbryant ranch prepack2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonesolution5 mg/mLoralCarilion Materials Management1986-12-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralRoxane Laboratories, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralREMEDYREPACK INC.2011-12-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralA S Medication Solutions Llc2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralREMEDYREPACK INC.2012-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-03-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralCardinal Health1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralHikma Pharmaceutical1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralMc Kesson Packaging Services A Business Unit Or Mc Kesson Corporation1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralWest Ward Pharmaceuticals Corp1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralMedsource Pharmaceuticals2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralH.J. Harkins Company, Inc.2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralA S Medication Solutions Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralRebel Distributors Corp1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLake Erie Medical DBA Quality Care Products LLC1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPhysicians Total Care, Inc.2002-04-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralbryant ranch prepack2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralRed Pharm Drug Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralRoxane Laboratories, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralAmerican Health Packaging2015-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralBlenheim Pharmacal, Inc.2013-07-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralWatson Laboratories, Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2011-09-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralA S Medication Solutions Llc1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2012-09-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2014-02-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPhysicians Total Care, Inc.2005-02-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralHikma Pharmaceutical1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralWest Ward Pharmaceuticals Corp1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralQualitest Pharmaceuticals2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralWest ward Pharmaceutical Corp2010-11-012015-12-29Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralMedsource Pharmaceuticals2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralH.J. Harkins Company, Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralA S Medication Solutions Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralRebel Distributors Corp1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLake Erie Medical DBA Quality Care Products LLC2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPhysicians Total Care, Inc.2002-03-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLake Erie Medical DBA Quality Care Products LLC2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralbryant ranch prepack2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralRed Pharm Drug Inc.2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralRoxane Laboratories, Inc.1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralAmerican Health Packaging2015-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralBlenheim Pharmacal, Inc.2012-12-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralC.O. Truxton, Inc.1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralREMEDYREPACK INC.2012-08-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-01-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPhysicians Total Care, Inc.2005-02-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralHikma Pharmaceutical1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralWest Ward Pharmaceuticals Corp2004-01-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralDIRECT RX2015-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralQualitest Pharmaceuticals2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-02-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralA S Medication Solutions Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralRebel Distributors Corp1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralLake Erie Medical DBA Quality Care Products LLC1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralA S Medication Solutions Llc2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPd Rx Pharmaceuticals, Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralProficient Rx LP2003-03-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralRed Pharm Drug Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonesolution5 mg/mLoralRoxane Laboratories, Inc.1986-12-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralGolden State Medical Supply, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralBlenheim Pharmacal, Inc.2011-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralC.O. Truxton, Inc.2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralMc Kesson Contract Packaging2011-12-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPerrigo New York Inc2006-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2014-08-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPd Rx Pharmaceuticals, Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPhysicians Total Care, Inc.2002-11-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralClinical Solutions Wholesale2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPreferred Pharmaceuticals, Inc.2013-06-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralRoxane Laboratories, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralBlenheim Pharmacal, Inc.2013-10-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralQualitest Pharmaceuticals2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2011-08-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/201oralNorthwind Pharmaceuticals2014-04-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLake Erie Medical & Surgial Supply DBA Quality Care Products LLC1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralA S Medication Solutions Llc1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPd Rx Pharmaceuticals, Inc.2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralProficient Rx LP2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralDispensing Solutions, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralGolden State Medical Supply, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralBlenheim Pharmacal, Inc.2011-06-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLiberty Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralMc Kesson Contract Packaging2011-10-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPerrigo New York Inc2006-05-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2014-06-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralA S Medication Solutions Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralRebel Distributors Corp1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralbryant ranch prepack2004-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralKeltman Pharmaceuticals Inc.2008-07-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralRoxane Laboratories, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralBlenheim Pharmacal, Inc.2010-03-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralQualitest Pharmaceuticals2004-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralREMEDYREPACK INC.2011-11-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/201oralNorthwind Pharmaceuticals2014-04-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2011-12-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPd Rx Pharmaceuticals, Inc.1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPhysicians Total Care, Inc.2002-04-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralClinical Solutions Wholesale2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralProficient Rx LP2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralDispensing Solutions, Inc.1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralRoxane Laboratories, Inc.2003-03-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralGolden State Medical Supply, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralBlenheim Pharmacal, Inc.2011-06-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLiberty Pharmaceuticals, Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralAphena Pharma Solutions Tennessee, Llc1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2013-11-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralA S Medication Solutions Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralSTAT Rx USA LLC2006-05-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralA S Medication Solutions Llc2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralCardinal Health2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralRoxane Laboratories, Inc.1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2014-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralBlenheim Pharmacal, Inc.2009-12-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralQualitest Pharmaceuticals2004-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2012-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralUnit Dose Services1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2015-10-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralPd Rx Pharmaceuticals, Inc.1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPhysicians Total Care, Inc.2003-08-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralClinical Solutions Wholesale1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralbryant ranch prepack2004-12-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralKeltman Pharmaceuticals Inc.2007-04-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralDIRECT RX2015-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralSTAT Rx USA LLC1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet2.5 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralA S Medication Solutions Llc2003-03-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralREMEDYREPACK INC.2013-07-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralCardinal Health2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralMed Vantx, Inc.2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPreferred Pharmaceuticals, Inc.2013-06-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralRoxane Laboratories, Inc.2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs1982-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralPreferred Pharmaceuticals, Inc.2014-04-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralAphena Pharma Solutions Tennessee, Inc.1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2013-05-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralSTAT Rx USA LLC1972-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralA S Medication Solutions Llc2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralCardinal Health2003-03-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralProficient Rx LP2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralDispensing Solutions, Inc.2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralSt Marys Medical Park Pharmacy2013-08-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralBlenheim Pharmacal, Inc.2014-02-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralWatson Laboratories, Inc.1987-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralREMEDYREPACK INC.2010-11-09Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralUnit Dose Services1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralRebel Distributors Corp2002-07-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralPhysicians Total Care, Inc.2004-10-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralClinical Solutions Wholesale, Llc2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet50 mg/1oralbryant ranch prepack2003-03-14Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralDispensing Solutions Inc.2008-05-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonesolution5 mg/mLoralRoxane Laboratories, Inc.1984-11-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralApotheca Inc.1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-02-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralREMEDYREPACK INC.2012-09-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralA S Medication Solutions Llc1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralREMEDYREPACK INC.2013-06-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralAidarex Pharmaceuticals LLC2003-02-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet5 mg/1oralCardinal Health1972-04-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet1 mg/1oralJUBILANT CADISTA PHARMACEUTICALS, INC.2005-06-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet10 mg/1oralTYA Pharmaceuticals1985-12-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralPreferred Pharmaceuticals, Inc.2015-03-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisonetablet20 mg/1oralWest Ward Pharmaceuticals Corp1974-02-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Prednisone Intensolsolution, concentrate5 mg/mLoralRoxane Laboratories, Inc.1985-02-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Over the Counter ProductsNot Available
International Brands
NameCompany
Delta-CortefUpjohn
MeticortenNot Available
OrasoneNot Available
Brand mixtures
NameLabellerIngredients
Metreton TabSchering Plough Canada Inc
SaltsNot Available
Categories
CAS number53-03-2
WeightAverage: 358.4281
Monoisotopic: 358.178023942
Chemical FormulaC21H26O5
InChI KeyInChIKey=XOFYZVNMUHMLCC-ZPOLXVRWSA-N
InChI
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
IUPAC Name
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-5,17-dione
SMILES
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassHydroxysteroids
Direct Parent21-hydroxysteroids
Alternative Parents
Substituents
  • 21-hydroxysteroid
  • Progestogin-skeleton
  • Pregnane-skeleton
  • 20-oxosteroid
  • 17-hydroxysteroid
  • Oxosteroid
  • 11-oxosteroid
  • 3-oxosteroid
  • 3-oxo-delta-1,4-steroid
  • Delta-1,4-steroid
  • Cyclohexanone
  • Tertiary alcohol
  • Cyclic alcohol
  • Alpha-hydroxy ketone
  • Cyclic ketone
  • Ketone
  • Hydrocarbon derivative
  • Primary alcohol
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis, Crohn's disease, acquired hemolytic anemia, congenital hypoplastic anemia, erythroblastopenia, adult secondary thrombocytopenia, adult idiopathic thrombocytopenia purpura, acute or subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute or chronic lymphocytic leukemia, Hodgkin's or non-Hodgkin's lynphomas, Waldenstrom's macroglobulinemia, primary brain tumors (adjunct), nephrotic syndrome, tuberculous meningitis, multiple sclerosis, myasthenia gravis. cerebral edema, chorioretinitis, diffuse posterior choroiditis, aleergic conjunctivitis, Herpes zoster ophthalmicus, anterior segment inflammation, iridocyclitis, iritis, keratitis, optoc neuritis, sympathetic ophthalmia, corneal marginal allergic ulcers, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy and aspiration pneumonitis.
PharmacodynamicsPrednisone, the most commonly-prescribed corticosteroid, is used to treat allograft rejection, asthma, systemic lupus erythematosus, and many other inflammatory states. Prednisone has some mineralocorticoid activity and thus may affect ion exchange in the kidney.
Mechanism of actionPrednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Prednisone can stimulate secretion of various components of gastric juice. Suppression of the production of corticotropin may lead to suppression of endogenous corticosteroids. Prednisone has slight mineralocorticoid activity, whereby entry of sodium into cells and loss of intracellular potassium is stimulated. This is particularly evident in the kidney, where rapid ion exchange leads to sodium retention and hypertension.
AbsorptionReadily absorbed from the gastrointestinal tract. Rayos, the delayed-release formulation, has a 4-hour release time. To compare, the delayed-release formulation has a Tmax of 6.0 - 6.5 hours in healthy male subjects, whereas the immediate-release formulation has a Tmax of 2.0 hours. The rate of absorption, Cmax, and exposure is comparable between formulations.
Volume of distributionNot Available
Protein bindingExtensively bound to plasma proteins.
Metabolism

Prednisone is completely converted to the active metabolite prednisolone by 11β-hydroxysteroid dehydrogenases. It is then further metabolized mainly in the liver. The exposure of prednisolone is 4-6 fold higher than that of prednisone.

SubstrateEnzymesProduct
Prednisone
PrednisoloneDetails
Route of eliminationExcreted in the urine as sulfate and glucuronide conjugates.
Half lifeHalf life of both the immediate- and delayed- release formulation is 2 to 3 hours.
ClearanceNot Available
ToxicityNot Available
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9918
Blood Brain Barrier+0.9383
Caco-2 permeable-0.5096
P-glycoprotein substrateSubstrate0.7861
P-glycoprotein inhibitor INon-inhibitor0.7847
P-glycoprotein inhibitor IINon-inhibitor0.8383
Renal organic cation transporterNon-inhibitor0.7463
CYP450 2C9 substrateNon-substrate0.8496
CYP450 2D6 substrateNon-substrate0.9138
CYP450 3A4 substrateSubstrate0.7407
CYP450 1A2 substrateNon-inhibitor0.9406
CYP450 2C9 inhibitorNon-inhibitor0.9072
CYP450 2D6 inhibitorNon-inhibitor0.9418
CYP450 2C19 inhibitorNon-inhibitor0.9253
CYP450 3A4 inhibitorNon-inhibitor0.8902
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9095
Ames testNon AMES toxic0.9132
CarcinogenicityNon-carcinogens0.9597
BiodegradationNot ready biodegradable0.925
Rat acute toxicity1.8914 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.95
hERG inhibition (predictor II)Non-inhibitor0.584
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Schering corp sub schering plough corp
  • Roxane laboratories inc
  • Wockhardt eu operations (swiss) ag
  • Muro pharmaceutical inc
  • Halsey drug co inc
  • Bayer pharmaceuticals corp
  • Pharmacia and upjohn co
  • Ferndale laboratories inc
  • Solvay pharmaceuticals
  • Parke davis div warner lambert co
  • Schwarz pharma inc
  • American therapeutics inc
  • Amneal pharmaceuticals ny llc
  • Cm bundy co
  • Cadista pharmaceuticals inc
  • Contract pharmacal corp
  • Duramed pharmaceuticals inc sub barr laboratories inc
  • Elkins sinn div ah robins co inc
  • Everylife
  • John j ferrante
  • Heather drug co inc
  • Impax laboratories inc
  • Inwood laboratories inc sub forest laboratories inc
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Kv pharmaceutical co
  • Lannett co inc
  • Lederle laboratories div american cyanamid co
  • Marshall pharmacal corp
  • Mutual pharmaceutical co inc
  • Nylos trading co inc
  • Panray corp sub ormont drug and chemical co inc
  • L perrigo co
  • Pharmavite pharmaceuticals
  • Phoenix laboratories inc
  • Purepac pharmaceutical co
  • Private formulations inc
  • Rexall drug co
  • Sandoz inc
  • Scherer laboratories inc
  • Sperti drug products inc
  • Superpharm corp
  • Teva pharmaceuticals usa inc
  • Udl laboratories inc
  • Upsher smith laboratories inc
  • Valeant pharmaceuticals international
  • Vangard laboratories inc div midway medical co
  • Vintage pharmaceuticals inc
  • Vitarine pharmaceuticals inc
  • Watson laboratories inc
  • West ward pharmaceutical corp
  • Whiteworth towne paulsen inc
Packagers
Dosage forms
FormRouteStrength
Tabletoral20 mg/20mg
Tabletoral1.0 mg
Tabletoral5 mg
Tabletoral
Solutionoral5 mg/mL
Tabletoral1 mg/1
Tabletoral10 mg/1
Tabletoral10 mg/201
Tabletoral2.5 mg/1
Tabletoral20 mg/1
Tabletoral20 mg/201
Tabletoral5 mg/1
Tabletoral50 mg/1
Solution, concentrateoral5 mg/mL
Tablet5 mg
Tablet, delayed releaseoral1 mg/1
Tablet, delayed releaseoral2 mg/1
Tablet, delayed releaseoral5 mg/1
Tabletoral50 mg
Tabletoral1 mg
Prices
Unit descriptionCostUnit
Sterapred DS 21 10 mg tablet Disp Pack64.0USD disp
Prednisone powder3.36USD g
Sterapred ds 10 mg tablet unipak2.93USD tablet
Prednisone 5 mg/ml solution1.17USD ml
PredniSONE 5 mg/5ml Solution0.5USD ml
Prednisone 50 mg tablet0.47USD tablet
Prednisone 20 mg tablet0.29USD tablet
Prednisone 10 mg tablet0.27USD tablet
Prednisone 2.5 mg tablet0.25USD tablet
Prednisone 1 mg tablet0.23USD tablet
Apo-Prednisone 50 mg Tablet0.18USD tablet
Winpred 1 mg Tablet0.12USD tablet
Apo-Prednisone 1 mg Tablet0.11USD tablet
Prednisone 5 mg tablet0.08USD tablet
Apo-Prednisone 5 mg Tablet0.04USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
CountryPatent NumberApprovedExpires (estimated)
United States64889602012-07-262020-03-14
United States66773262012-07-262020-03-14
United States83091242012-07-262024-04-23
United States83944072012-07-262024-04-23
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point230 - 235 °C (decomposes)MSDS
water solubilityVery slightly solubleMSDS
logP1.46MSDS
Predicted Properties
PropertyValueSource
Water Solubility0.111 mg/mLALOGPS
logP2.07ALOGPS
logP1.66ChemAxon
logS-3.5ALOGPS
pKa (Strongest Acidic)12.58ChemAxon
pKa (Strongest Basic)-3.3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area91.67 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity97.57 m3·mol-1ChemAxon
Polarizability38.17 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (12.5 KB)
Spectra
Spectrum TypeDescriptionSplash Key
MSMass Spectrum (Electron Ionization)splash10-bzl4000000-1a9b3a7e18f6088d28dbView in MoNA
References
Synthesis Reference

Jean Buendia, Michel Vivat, “Process for the production of prednisone 17.21-diacylates.” U.S. Patent US4601854, issued May, 1982.

US4601854
General References
  1. FDA label
External Links
ATC CodesA07EA03H02AB07
AHFS Codes
  • 68:04.00
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (132 KB)
Interactions
Drug Interactions
Drug
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Prednisone.
Acetylsalicylic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prednisone.
AldesleukinPrednisone may decrease the antineoplastic activities of Aldesleukin.
AlogliptinThe therapeutic efficacy of Alogliptin can be decreased when used in combination with Prednisone.
Aluminum hydroxideThe bioavailability of Prednisone can be decreased when combined with Aluminum hydroxide.
Amphotericin BPrednisone may increase the hypokalemic activities of Amphotericin B.
AprepitantThe serum concentration of Prednisone can be increased when it is combined with Aprepitant.
AripiprazoleThe serum concentration of Aripiprazole can be decreased when it is combined with Prednisone.
AtazanavirThe serum concentration of Prednisone can be increased when it is combined with Atazanavir.
Atracurium besylateAtracurium besylate may increase the adverse neuromuscular activities of Prednisone.
Benzoic AcidThe therapeutic efficacy of Benzoic Acid can be decreased when used in combination with Prednisone.
BoceprevirThe serum concentration of Prednisone can be increased when it is combined with Boceprevir.
CalcitriolThe therapeutic efficacy of Calcitriol can be decreased when used in combination with Prednisone.
Calcium carbonateThe bioavailability of Prednisone can be decreased when combined with Calcium carbonate.
CanagliflozinThe therapeutic efficacy of Canagliflozin can be decreased when used in combination with Prednisone.
CapromabPrednisone may decrease effectiveness of Capromab as a diagnostic agent.
CarbamazepineThe serum concentration of Prednisone can be decreased when it is combined with Carbamazepine.
CeritinibPrednisone may increase the hyperglycemic activities of Ceritinib.
ChlorotrianiseneThe serum concentration of Prednisone can be increased when it is combined with Chlorotrianisene.
ChlorpropamideThe therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Prednisone.
ClarithromycinThe serum concentration of Prednisone can be increased when it is combined with Clarithromycin.
CobicistatThe serum concentration of Prednisone can be increased when it is combined with Cobicistat.
ColesevelamColesevelam can cause a decrease in the absorption of Prednisone resulting in a reduced serum concentration and potentially a decrease in efficacy.
CorticorelinThe therapeutic efficacy of Corticorelin can be decreased when used in combination with Prednisone.
CyclosporineThe serum concentration of the active metabolites of Prednisone can be increased when Prednisone is used in combination with Cyclosporine.
DarunavirThe serum concentration of Prednisone can be increased when it is combined with Darunavir.
DeferasiroxThe risk or severity of adverse effects can be increased when Prednisone is combined with Deferasirox.
DenosumabThe risk or severity of adverse effects can be increased when Denosumab is combined with Prednisone.
DesmopressinThe risk or severity of adverse effects can be increased when Prednisone is combined with Desmopressin.
DihydrotestosteronePrednisone may increase the fluid retaining activities of Dihydrotestosterone.
EnzalutamideThe serum concentration of Prednisone can be decreased when it is combined with Enzalutamide.
FluconazoleThe serum concentration of Prednisone can be increased when it is combined with Fluconazole.
FosaprepitantThe serum concentration of Prednisone can be increased when it is combined with Fosaprepitant.
FosphenytoinThe serum concentration of Prednisone can be decreased when it is combined with Fosphenytoin.
GliclazideThe therapeutic efficacy of Gliclazide can be decreased when used in combination with Prednisone.
GlimepirideThe therapeutic efficacy of Glimepiride can be decreased when used in combination with Prednisone.
GliquidoneThe therapeutic efficacy of Gliquidone can be decreased when used in combination with Prednisone.
GlyburideThe therapeutic efficacy of Glyburide can be decreased when used in combination with Prednisone.
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Prednisone.
HydrocodoneThe serum concentration of Hydrocodone can be decreased when it is combined with Prednisone.
IcosapentThe risk or severity of adverse effects can be increased when Prednisone is combined with Icosapent.
IdelalisibThe serum concentration of Prednisone can be increased when it is combined with Idelalisib.
IndacaterolIndacaterol may increase the hypokalemic activities of Prednisone.
IndinavirThe serum concentration of Prednisone can be increased when it is combined with Indinavir.
Insulin AspartThe therapeutic efficacy of Insulin Aspart can be decreased when used in combination with Prednisone.
Insulin DetemirThe therapeutic efficacy of Insulin Detemir can be decreased when used in combination with Prednisone.
Insulin GlargineThe therapeutic efficacy of Insulin Glargine can be decreased when used in combination with Prednisone.
Insulin GlulisineThe therapeutic efficacy of Insulin Glulisine can be decreased when used in combination with Prednisone.
Insulin LisproThe therapeutic efficacy of Insulin Lispro can be decreased when used in combination with Prednisone.
Insulin RegularThe therapeutic efficacy of Insulin Regular can be decreased when used in combination with Prednisone.
Insulin, isophaneThe therapeutic efficacy of Insulin, isophane can be decreased when used in combination with Prednisone.
IsoniazidThe serum concentration of Isoniazid can be decreased when it is combined with Prednisone.
ItraconazoleThe serum concentration of Prednisone can be increased when it is combined with Itraconazole.
KetoconazoleThe serum concentration of Prednisone can be increased when it is combined with Ketoconazole.
LeflunomideThe risk or severity of adverse effects can be increased when Prednisone is combined with Leflunomide.
LinagliptinThe therapeutic efficacy of Linagliptin can be decreased when used in combination with Prednisone.
Magnesium oxideThe bioavailability of Prednisone can be decreased when combined with Magnesium oxide.
MetforminThe therapeutic efficacy of Metformin can be decreased when used in combination with Prednisone.
MifepristoneThe therapeutic efficacy of Prednisone can be decreased when used in combination with Mifepristone.
MitotaneThe serum concentration of Prednisone can be decreased when it is combined with Mitotane.
NatalizumabThe risk or severity of adverse effects can be increased when Prednisone is combined with Natalizumab.
NefazodoneThe serum concentration of Prednisone can be increased when it is combined with Nefazodone.
NelfinavirThe serum concentration of Prednisone can be increased when it is combined with Nelfinavir.
NicorandilThe risk or severity of adverse effects can be increased when Prednisone is combined with Nicorandil.
NimodipineThe serum concentration of Nimodipine can be decreased when it is combined with Prednisone.
OxandrolonePrednisone may increase the fluid retaining activities of Oxandrolone.
PhenobarbitalThe serum concentration of Prednisone can be decreased when it is combined with Phenobarbital.
PhenytoinThe serum concentration of Prednisone can be decreased when it is combined with Phenytoin.
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Prednisone.
PosaconazoleThe serum concentration of Prednisone can be increased when it is combined with Posaconazole.
PrimidoneThe serum concentration of Prednisone can be decreased when it is combined with Primidone.
RepaglinideThe therapeutic efficacy of Repaglinide can be decreased when used in combination with Prednisone.
RifabutinThe serum concentration of Prednisone can be decreased when it is combined with Rifabutin.
RifampicinThe serum concentration of Prednisone can be decreased when it is combined with Rifampicin.
RifapentineThe serum concentration of Prednisone can be decreased when it is combined with Rifapentine.
RitonavirThe serum concentration of Prednisone can be increased when it is combined with Ritonavir.
RoflumilastRoflumilast may increase the immunosuppressive activities of Prednisone.
Salicylate-sodiumThe risk or severity of adverse effects can be increased when Salicylate-sodium is combined with Prednisone.
SaquinavirThe serum concentration of Prednisone can be increased when it is combined with Saquinavir.
SaxagliptinThe serum concentration of Saxagliptin can be decreased when it is combined with Prednisone.
Sipuleucel-TThe therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Prednisone.
Somatropin recombinantThe therapeutic efficacy of Prednisone can be decreased when used in combination with Somatropin recombinant.
SparfloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Sparfloxacin.
TacrineThe risk or severity of adverse effects can be increased when Prednisone is combined with Tacrine.
TacrolimusThe risk or severity of adverse effects can be increased when Tacrolimus is combined with Prednisone.
TelaprevirThe serum concentration of Telaprevir can be decreased when it is combined with Prednisone.
TelithromycinThe serum concentration of Prednisone can be increased when it is combined with Telithromycin.
TesamorelinThe serum concentration of the active metabolites of Prednisone can be reduced when Prednisone is used in combination with Tesamorelin resulting in a loss in efficacy.
TestosteronePrednisone may increase the fluid retaining activities of Testosterone.
TofacitinibPrednisone may increase the immunosuppressive activities of Tofacitinib.
TolbutamideThe therapeutic efficacy of Tolbutamide can be decreased when used in combination with Prednisone.
TorasemidePrednisone may increase the hypokalemic activities of Torasemide.
TrastuzumabTrastuzumab may increase the neutropenic activities of Prednisone.
TrichlormethiazidePrednisone may increase the hypokalemic activities of Trichlormethiazide.
VildagliptinThe therapeutic efficacy of Vildagliptin can be decreased when used in combination with Prednisone.
VoriconazoleThe serum concentration of Prednisone can be increased when it is combined with Voriconazole.
WarfarinPrednisone may increase the anticoagulant activities of Warfarin.
Food Interactions
  • Avoid alcohol.
  • Avoid taking with grapefruit juice.
  • Take with food to reduce irritation.
  • When Rayos, the delayed-release tablet, is taken without food, Cmax and bioavailability were lower compared to the fed state.

Targets

1. Glucocorticoid receptor

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: agonist

Components

Name UniProt ID Details
Glucocorticoid receptor P04150 Details

References:

  1. Liu BG, Li ZY, Du M: [Effects of jingui shenqi pill combined prednisone on expression of glucocorticoid receptor and its clinical effect in treating bullous pemphigoid patients] Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Oct;26(10):881-4. Pubmed
  2. Friel PN, Alexander T, Wright JV: Suppression of adrenal function by low-dose prednisone: assessment with 24-hour urinary steroid hormone profiles—a review of five cases. Altern Med Rev. 2006 Mar;11(1):40-6. Pubmed
  3. Diez JJ, Iglesias P: Pharmacological therapy of Cushing’s syndrome: drugs and indications. Mini Rev Med Chem. 2007 May;7(5):467-80. Pubmed
  4. Yano A, Fujii Y, Iwai A, Kawakami S, Kageyama Y, Kihara K: Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6012-7. Pubmed
  5. Yano A, Fujii Y, Iwai A, Kageyama Y, Kihara K: Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells. Clin Cancer Res. 2006 May 15;12(10):3003-9. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

2. Corticosteroid 11-beta-dehydrogenase isozyme 1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: ligand

Components

Name UniProt ID Details
Corticosteroid 11-beta-dehydrogenase isozyme 1 P28845 Details

References:

  1. Raza K, Hardy R, Cooper MS: The 11beta-hydroxysteroid dehydrogenase enzymes—arbiters of the effects of glucocorticoids in synovium and bone. Rheumatology (Oxford). 2010 Nov;49(11):2016-23. doi: 10.1093/rheumatology/keq212. Epub 2010 Jul 15. Pubmed

Enzymes

1. Cytochrome P450 3A4

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor inducer

Components

Name UniProt ID Details
Cytochrome P450 3A4 P08684 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

2. Cytochrome P450 2C19

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inducer

Components

Name UniProt ID Details
Cytochrome P450 2C19 P33261 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

Carriers

1. Serum albumin

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Serum albumin P02768 Details

References:

  1. Ferry JJ, Wagner JG: The nonlinear pharmacokinetics of prednisone and prednisolone. II. Plasma protein binding of prednisone and prednisolone in rabbit and human plasma. Biopharm Drug Dispos. 1987 May-Jun;8(3):261-72. Pubmed

Transporters

1. Multidrug resistance protein 1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Multidrug resistance protein 1 P08183 Details

References:

  1. Nagy H, Goda K, Fenyvesi F, Bacso Z, Szilasi M, Kappelmayer J, Lustyik G, Cianfriglia M, Szabo G Jr: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochem Biophys Res Commun. 2004 Mar 19;315(4):942-9. Pubmed
  2. Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW: Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharm Res. 2003 Nov;20(11):1794-803. Pubmed
  3. Dilger K, Schwab M, Fromm MF: Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoprotein. Inflamm Bowel Dis. 2004 Sep;10(5):578-83. Pubmed

2. Solute carrier organic anion transporter family member 1A2

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier organic anion transporter family member 1A2 P46721 Details

References:

  1. Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. Pubmed

Comments
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Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:11