Relapsed Small Lymphocytic Lymphoma

Also known as: Small Lymphocytic Lymphoma, Relapsed

Drug	Drug Name	Drug Description
DB11952	Duvelisib	An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
DB09054	Idelalisib	An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
DB16582	Lisocabtagene maraleucel	A CAR T-cell therapy for treatment resistant or more severe B-cell lymphomas.

Drug	Drug Name	Target	Type
DB11952	Duvelisib	Cytochrome P450 3A4	enzyme
DB11952	Duvelisib	P-glycoprotein 1	transporter
DB11952	Duvelisib	ATP-binding cassette sub-family G member 2	transporter
DB11952	Duvelisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
DB11952	Duvelisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
DB09054	Idelalisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
DB09054	Idelalisib	ATP-binding cassette sub-family G member 2	transporter
DB09054	Idelalisib	P-glycoprotein 1	transporter
DB09054	Idelalisib	Aldehyde oxidase	enzyme
DB09054	Idelalisib	Cytochrome P450 2C8	enzyme
DB09054	Idelalisib	Cytochrome P450 2C19	enzyme
DB09054	Idelalisib	Cytochrome P450 2B6	enzyme
DB09054	Idelalisib	Cytochrome P450 3A4	enzyme
DB09054	Idelalisib	Solute carrier organic anion transporter family member 1B1	transporter
DB09054	Idelalisib	Solute carrier organic anion transporter family member 1B3	transporter
DB09054	Idelalisib	Cytochrome P450 3A5	enzyme
DB09054	Idelalisib	Cytochrome P450 3A43	enzyme
DB09054	Idelalisib	Cytochrome P450 3A7	enzyme
DB09054	Idelalisib	UDP-glucuronosyltransferase 1-4	enzyme
DB16582	Lisocabtagene maraleucel	B-lymphocyte antigen CD19	target

Drug	Drug Name	Phase	Status	Count
DB00531	Cyclophosphamide	2	Active Not Recruiting	1
DB01073	Fludarabine	2	Active Not Recruiting	2
DB01042	Melphalan	2	Active Not Recruiting	1
DB00688	Mycophenolate mofetil	2	Active Not Recruiting	1
DB00877	Sirolimus	2	Active Not Recruiting	1
DB17366	MB-102 CD123 CAR	Not Available	Enrolling by Invitation	1