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Displaying drugs 26 - 50 of 8682 in total
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Flavone
Approved
Experimental
Matched Synonyms: … 2-Phenyl-4-chromone ... 2-Phenyl-4-benzopyron ... 2-Phenylbenzopyran-4-one …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Matched Iupac: … 2-phenyl-4H-chromen-4-one …
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Products: … ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ ... EPINOR 4 MG/4 ML IV INFÜZYONLUK KONSANTRE ÇÖZELTİ,10 AMPUL ... FOREFRIN 4 MG/4 ML I.V. INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 AMPUL …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Products: … ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ ... EPINOR 4 MG/4 ML IV INFÜZYONLUK KONSANTRE ÇÖZELTİ,10 AMPUL ... FOREFRIN 4 MG/4 ML I.V. INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 AMPUL …
Zafirlukast
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate ... 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamide …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5 …
Piperaquine
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Iupac: … 7-chloro-4-(4-{3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl}piperazin-1-yl)quinoline …
Matched Salts cas: … 911061-10-4 …
Matched Iupac: … 7-chloro-4-(4-{3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl}piperazin-1-yl)quinoline …
Matched Salts cas: … 911061-10-4 …
Nintedanib
Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Synonyms: … methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3 …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Products: … OFEV 100 MG ... OFEV® 100 MG ... VARGATEF 100 MG …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Products: … OFEV 100 MG ... OFEV® 100 MG ... VARGATEF 100 MG …
Buspirone
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Synonyms: … 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione …
Matched Iupac: … 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione …
Matched Products: … NOPIRON 5 MG TABLET, 100 ADET ... NOPIRON 10 MG TABLET, 100 ADET …
Matched Iupac: … 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione …
Matched Products: … NOPIRON 5 MG TABLET, 100 ADET ... NOPIRON 10 MG TABLET, 100 ADET …
Nomifensine
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine ... 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Salts cas: … 32795-47-4 …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Salts cas: … 32795-47-4 …
Erlotinib
Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Synonyms: … [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine …
Matched Iupac: … N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine …
Matched Products: … ERLONIB 100 ... ERLONIB 100 FILM COATED TABLETS 100 MG ... เออร์โลนิบ 100 …
Matched Iupac: … N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine …
Matched Products: … ERLONIB 100 ... ERLONIB 100 FILM COATED TABLETS 100 MG ... เออร์โลนิบ 100 …
Ertugliflozin
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Synonyms: … (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane ... 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose ... β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …
Matched Salts cas: … 1210344-83-4 …
Matched Mixtures name: … สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) ... สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …
Matched Salts cas: … 1210344-83-4 …
Matched Mixtures name: … สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) ... สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม) …
Lesinurad
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Buclizine
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …
Matched Iupac: … 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)(phenyl)methyl]piperazine …
Matched Iupac: … 1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)(phenyl)methyl]piperazine …
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Synonyms: … 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea ... N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Alclofenac
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … (4-Allyloxy-3-chlorphenyl)essigsäure ... [4-(allyloxy)-3-chlorophenyl]acetic acid ... 3-Chloro-4-(2-propenyloxy)benzeneacetic acid …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Chlorhexidine
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … HIDROX PLUS MERHEM, 100 G ... SAVSID KONSANTRE SOLUSYON, 100 ML ... Stanhexidine 4% With Isopropyl Alcohol 4% …
Matched Products: … Dyna-hex 4 ... Dyna-Hex 4 ... SurgiBath 4% …
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … HIDROX PLUS MERHEM, 100 G ... SAVSID KONSANTRE SOLUSYON, 100 ML ... Stanhexidine 4% With Isopropyl Alcohol 4% …
Matched Products: … Dyna-hex 4 ... Dyna-Hex 4 ... SurgiBath 4% …
Drospirenone
Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Synonyms: … 6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET …
Matched Products: … Lyzbet 4 mg Filmtabletten ... GYNETS® 4 MG TABLETAS RECUBIERTAS ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET …
Matched Products: … Lyzbet 4 mg Filmtabletten ... GYNETS® 4 MG TABLETAS RECUBIERTAS ... ZLYNDA 4 MG FİLM KAPLI TABLET, 28 ADET …
Ethynodiol diacetate
A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Synonyms: … 17α-Ethynylestr-4-ene-3β,17β-diol acetate ... 3β, 17β-Diacetoxy-17α-ethynyl-4-oestrene ... 17α-Ethynyl-4-estrene-3β,17β-diol diacetate …
Dioxybenzone
Dioxybenzone, or benzophenone-8, is an organic compound derived from DB01878 that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% .
Approved
Matched Synonyms: … 2,2'-Dihydroxy-4-methoxybenzophenone …
Apraclonidine
Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Synonyms: … 4-Aminoclonidine …
Ethyl ferulate
Approved
Experimental
Matched Synonyms: … Ethyl 4'-hydroxy-3'-methoxycinnamate …
Matched Iupac: … ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate …
Matched Iupac: … ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Acebutolol
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Synonyms: … 3'-acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide ... N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide ... N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide …
Matched Iupac: … N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanamide …
Matched Products: … Rhotral 100 ... Monitan 100 ... Acebutolol-100 …
Matched Iupac: … N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanamide …
Matched Products: … Rhotral 100 ... Monitan 100 ... Acebutolol-100 …
Flucloxacillin
Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … -4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin ... (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … Flucloxacillin WABO 4 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … Flucloxacillin WABO 4 g Pulver zur Herstellung einer Injektions-/Infusionslösung …
Rosuvastatin
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Mixtures name: … ROSPIRIN 20/100 KAPSUL, 30 ADET ... ROSPIRIN 20/100 KAPSUL, 90 ADET ... RosuASS 5 mg/100 mg Hartkapseln …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Mixtures name: … ROSPIRIN 20/100 KAPSUL, 30 ADET ... ROSPIRIN 20/100 KAPSUL, 90 ADET ... RosuASS 5 mg/100 mg Hartkapseln …
Dexibuprofen
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Synonyms: … (2S)-2-(4-isobutylphenyl)propanoic acid ... (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Products: … XIALOX® 100 MG ... TAFLAX 100 MG TABLETAS CUBIERTAS …
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Products: … XIALOX® 100 MG ... TAFLAX 100 MG TABLETAS CUBIERTAS …
Displaying drugs 26 - 50 of 8682 in total