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Displaying drugs 76 - 100 of 8130 in total

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles …
Matched Mixtures name: … FENIXIL-OF …

Terizidone

Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.
Approved
Investigational
Matched Description: … Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Trolamine

Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Description: … against the auto-oxidation of animal and vegetable fats [A27174]. ... It is a bifunctional compound that exhibits both properties of alcohols and amines. ... Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Ergometrine

An ergot alkaloid with uterine and vascular smooth muscle contractile properties.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … several good manufacturing practice conditions of use. ... Liquid drain cleaners contain 25 to 36% of potassium hydroxide [L1946]. ... Recently, it has been studied for efficacy and tolerability in the treatment of warts. …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … It is used for active immunization of children 7 years of age or older, and adults, for prevention of …
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Categories: … combinations of penicillins …

Omidenepag isopropyl

Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. ... [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the …
Matched Categories: … combinations of sulfonamides …

Bamlanivimab

Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike (S) protein, which is described to...
Approved
Investigational
Matched Description: … Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from ... Bamlanivimab consists of two identical light chains of 214 amino acids and two identical heavy chains ... of 455 amino acids each; the Fc region is unmodified. …

Butoconazole

Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Categories: … combinations of imidazole derivatives …

Sodium cellulose phosphate

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Categories: … Drugs for Treatment of Hypercalcemia …

Artemisia vulgaris root

Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational

Tiludronic acid

Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Description: … [A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Diclofenamide

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …

Methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Categories: … combinations of barbiturates …

Rolitetracycline

A pyrrolidinylmethyl tetracycline.
Approved
Matched Categories: … combinations of tetracyclines …

Propyliodone

Radiopaque medium usually in oil; used in bronchography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Ferumoxides

Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Mazindol

Mazindol is a tricyclic anorexigenic agent that is unrelated to and less toxic than amphetamine, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. Mazindol is only approved in the United States for the treatment of Duchenne...
Approved
Investigational
Matched Description: … It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter ... is not marketed or available in the United States for use in the treatment of obesity. ... Mazindol is only approved in the United States for the treatment of Duchenne muscular dystrophy, and …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Vosoritide

Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans. It results from a gain-of-function missense mutation in FGFR3 that results in a dramatic suppression of bone growth, both in volume and in length.[A242273,A242277] Treatment for achondroplasia includes both surgical and pharmacological interventions, the...
Approved
Investigational
Matched Description: … suppression of bone growth, both in volume and in length. ... Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans ... [A242277] It results from a gain-of-function missense mutation in _FGFR3_ that results in a dramatic …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Lutetium Lu 177 dotatate

A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with molecules carrying radioactive particles that bind to specific receptors expressed by the tumour. Lutetium Lu 177 dotatate may also be referred to as...
Approved
Investigational
Matched Description: … The presence of a radioligand allows monitoring of treatment response post therapy and prior to next ... fraction of the dose delivery which may be clinically beneficial in estimating the intensity of lesion ... A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of …
Matched Categories: … Diagnostic Uses of Chemicals …

Zinc ascorbate

Approved
Nutraceutical
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Dihydrostreptomycin

Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … In humans, the use of dihydrostreptomycin has been associated with ototoxicity. ... The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate …

Hetacillin

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … The name "penicillin" can either refer to several variants of penicillin available, or to the group of ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated ... Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused …
Matched Categories: … combinations of penicillins …
Displaying drugs 76 - 100 of 8130 in total