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Displaying drugs 101 - 125 of 700 in total
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Synonyms: … cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L …
Matched Description: … It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection ... Signifor LAR 40mg powder and solvent for suspension for injection …
A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Synonyms: … N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine ... o-methyldiphenhydramine ... o-monomethyldiphenhydramine …
Matched Description: … A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm …
Matched Mixtures name: … MYOGESIC-O ... MYOGESIC-OR ... Orphenadrine Citrate, Aspirin and Caffeine …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. ... It was also approved by FDA and EMA in 2016. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... A to manage and prevent bleeding episodes. ... events like trauma or surgery. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Experimental
Matched Synonyms: … 6-O-phosphono-L-gulonic acid …
Experimental
Matched Synonyms: … 4-O-phosphono-L-threonic acid …
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. ... of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical …
Matched Mixtures name: … Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride ... CVS Health Cold and Hot Roll-On ... FAK Care4 Bus and School Yellow ORM D …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Analgesics and Anesthetics ... Antipruritics and Local Anesthetics …
Matched Products: … QC Cool and Heat Roll-On ... Omeza Licodaine Pain and Itch Relief Oil ... Foster and Thrive …
Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Iupac: … }oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid ... 6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy
Experimental
Matched Synonyms: … 3-O-Methylglucose ... O(3)-methyl-D-glucose …
Matched Name: … 3-O-Methyl-d-glucose …
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Matched Description: … This gas is an important signaling molecule in the body of mammals including humans and is an extremely ... It is also a toxic air pollutant produced by automobile engines and power plants. ... Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. …
Matched Categories: … Nitrates and Nitrites ... Compounds used in a research, industrial, or household setting …
Matched Products: … GNO Warming Gel (Provides sense of heating and pain relieft, Fermented Cabbage Extract) ... NO more Eye Pain (Relieves dryness of the eye, Protects against irritaion of the eye) redness of the ... GNO Cooling Gel (Provides sense of cooling and pain relief, Acne Treatment, Fermented Cabbage Extract …
Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in ... the Treatment of Idiopathic Pulmonary Fibrosis). …
Approved
Matched Synonyms: … p-Menthan-3-ol
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexan-1-ol
Matched Mixtures name: … CVS Health Cold and Hot Roll-On ... CAMPHOR, EUCALYPTUS OIL and MENTHOL ... Lidocaine 4 Percent and Menthol 1 Percent Roll-On
Matched Products: … CVS Cold and Hot Roll-On ... QC Cool and Heat Roll-On ... Rite Aid Hot and Cold Roll On
Experimental
Matched Synonyms: … 5'-O-(L-Tyrosylsulfamoyl)adenosine …
Matched Iupac: … 6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-(4-hydroxyphenyl)propan-1-one
Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched International brands: … Zyven-OD
Matched Synonyms: … ODV ... O-desmethylvenlafaxine …
Matched Description: … 16% in the US alone and 12.8% in Europe. ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine ... Although the exact mechanism of pathophysiology is still unknown, imbalances or deficiencies of monoamines …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. ... coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … and has structural and functional characteristics similar to those of endogenous factor IX. ... Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, …
Matched Products: … BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Iupac: … (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl …
Matched Description: … List of Essential Medicines as one of the most effective and safe medicines employed in a health system ... for treating constipation and its efficacy in managing PSE may never be formally confirmed or refuted ... a readily available generic and brand-name non-prescription medication listed on the World Health Organization's …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Orb-lactulose …
An obsolete fungicide used to control various pathogens on cereals and seed potatoes.
Experimental
Matched Synonyms: … o-Toluanilide ... o-Methylbenzanilide …
Matched Description: … An obsolete fungicide used to control various pathogens on cereals and seed potatoes. …
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Synonyms: … Menthyl-O-aminobenzoate …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products ... [T200] It is currently required to be named as meradimate in all FDA approved OTC products. ... Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 ... SPF 15 Spray-ON Sunscreen ... SPF 30+ Spray-ON Sunscreen …
A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases,...
Approved
Investigational
Matched Synonyms: … O-Acetylcholine …
Matched Description: … sympathetic effector junctions, and at many sites in the central nervous system. ... transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Miochol E Acetylcholine Chloride Oph Soln …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... delete certain portions of human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... of its pharmacological activity sometimes limits its usefulness. ... be good candidates for using the agent owing to its physical effects on the gut. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … 3-O-Ethylmorphine …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Experimental
Matched Synonyms: … D-pyridoxyl-N,O-cycloserylamide-5-monophosphate …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
Displaying drugs 101 - 125 of 700 in total