Displaying drugs 101 - 125 of 215 in total
Mycophenolic acid
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Salts name: … Mycophenolate sodium …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents …
Matched Salts name: … Mycophenolate sodium …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents …
Picosulfuric acid
Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in...
Approved
Matched Description: … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian ... market in 2005 and has been used in European countries for many years. ... Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Salts name: … Sodium picosulfate monohydrate ... Sodium picosulphate anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... sodium picosulfate ... sodium picosulfate, combinations …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Salts name: … Sodium picosulfate monohydrate ... Sodium picosulphate anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... sodium picosulfate ... sodium picosulfate, combinations …
Ornithine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Description: … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Stannous chloride
Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Description: … Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing ... These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Spectrum Performa Multivitamins and Minerals Tablets …
Propanoic acid
Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. Its use as a food...
Approved
Vet approved
Matched Description: … as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and ... Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals ... Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide. …
Matched Salts name: … Sodium propionate …
Matched Categories: … sodium propionate …
Matched Salts name: … Sodium propionate …
Matched Categories: … sodium propionate …
Leucovorin
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … while the dextro form is slowly excreted by the kidneys. ... levo-isomer has been shown to be rapidly converted to the biologically available methyl-tetrahydrofolate form ... Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary …
Matched Salts name: … Leucovorin sodium …
Matched Categories: … sodium folinate ... Enzymes and Coenzymes ... Folic Acid and Derivatives …
Matched Salts name: … Leucovorin sodium …
Matched Categories: … sodium folinate ... Enzymes and Coenzymes ... Folic Acid and Derivatives …
Tiopronin
Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. Patients with cystinuria excrete high levels of cystine in their urine and are at risk for kidney stone formation. Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion,...
Approved
Investigational
Matched Description: … of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium ... and protein, and urinary alkalinization. ... , and prevent kidney stone formation. …
Matched Categories: … Reducing and Complexing Thiol ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones …
Matched Categories: … Reducing and Complexing Thiol ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones …
Mipomersen
Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in...
Approved
Investigational
Matched Description: … Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic ... Due to this serious risk of liver toxicity, mipomersen sodium is only available to patients under the ... Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein …
Matched Salts name: … Mipomersen sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Salts name: … Mipomersen sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Magnesium chloride
Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Description: … Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Phoxilium 1.2 mmol/l phosphate solution for haemodialysis/haemofiltration ... PHOXILIUM 1.2 MMOL/L PHOSPHATE SOLUTION FOR HAEMODIALYSIS/HAEMOFILTRATION …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Mixtures name: … Plasma-Lyte 148 and dextrose ... Phoxilium 1.2 mmol/l phosphate solution for haemodialysis/haemofiltration ... PHOXILIUM 1.2 MMOL/L PHOSPHATE SOLUTION FOR HAEMODIALYSIS/HAEMOFILTRATION …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Synthetic Conjugated Estrogens, B
Synthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances. The estrogenic substances are: sodium estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, sodium 17β-estradiol sulfate, and sodium Δ8,9-dehydroestrone sulfate. This...
Approved
Matched Description: … , and sodium Δ8,9-dehydroestrone sulfate. ... sulfate and sodium equilin sulfate), they vary by their original source (such as horse-, human-, or ... The estrogenic substances are: sodium estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Tazarotene
Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids. It is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and sun damaged skin (photodamage).
Approved
Investigational
Matched Description: … Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids ... found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.1% ... Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.05% …
Matched Categories: … tazarotene and ulobetasol ... Skin and Mucous Membrane Agents …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.1% ... Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.05% …
Matched Categories: … tazarotene and ulobetasol ... Skin and Mucous Membrane Agents …
Synthetic Conjugated Estrogens, A
Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, and sodium 17β-estradiol sulfate. This blend of nine estrogen derivatives...
Approved
Matched Description: … sulfate, and sodium 17β-estradiol sulfate. ... sulfate and sodium equilin sulfate), they vary by their original source (such as horse-, human-, or ... sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Pectin
Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … , ammonium, potassium or sodium salts or as acid amides. ... [L1961] The carboxylic group of the constituents of pectin can exist in the form of esters, free acids …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry …
Bovine type I collagen
Bovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration . Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing...
Approved
Matched Description: … skin tears) and draining wounds [L2500]. ... and effective wound healing [L2427], [L2450]. ... It plays a vital role in cell growth, differentiation, attachment, and migration [L2481]. …
Esterified estrogens
Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that ... It is being also for the prevention and treatment of osteoporosis. …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …
Triamterene
Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side. Since it acts on...
Approved
Matched Description: … It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion ... [A177985] Since it acts on the distal nephron where only a small fraction of sodium ion reabsorption ... Triamterene is a weak antagonist of folic acid, and a photosensitizing drug. …
Matched Mixtures name: … Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide …
Matched Categories: … Sodium Channel Blockers ... Epithelial Sodium Channel Blockers …
Matched Mixtures name: … Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide …
Matched Categories: … Sodium Channel Blockers ... Epithelial Sodium Channel Blockers …
Ranolazine
Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant ... piperazine derivative used for the management of this condition, offering relief from uncomfortable and …
Matched Categories: … Sodium Channel Blockers …
Matched Categories: … Sodium Channel Blockers …
Aliskiren
Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Description: … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. ... Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension …
Matched Categories: … valsartan and aliskiren ... aliskiren and amlodipine ... aliskiren and hydrochlorothiazide ... aliskiren, amlodipine and hydrochlorothiazide …
Matched Categories: … valsartan and aliskiren ... aliskiren and amlodipine ... aliskiren and hydrochlorothiazide ... aliskiren, amlodipine and hydrochlorothiazide …
Poractant alfa
Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. It is used to treat Respiratory Distress Syndrome (RDS) in premature infants with an endogenous pulmonary surfactant deficiency. Poractant alfa is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids)...
Approved
Matched Description: … Poractant alfa is a creamy white suspension of this extract in 0.9% sodium chloride solution. ... Poractant alfa is a pulmonary surfactant marketed as Curosurf in the United States and Canada. ... 1% hydrophobic low molecular weight proteins (surfactant associated proteins SP-B and SP-C). …
Hexylresorcinol
Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic.
The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Description: … for pain relief and first aid antiseptic. ... It exhibits antiseptic, anthelmintic, and local anesthetic properties. ... It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges …
Butamben
Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics. Due to its very low water solubility, butamben is considered to be suitable only for...
Approved
Withdrawn
Matched Description: … Butamben is a local anesthetic in the form of n-butyl-p-aminobenzoate. ... [A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated …
Indapamide
The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …
Inositol nicotinate
Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and ... Niacin exists in different forms including nicotinic acid, nicotinamide and other derivatives such as ... vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and …
Matched Categories: … Nicotinic Acid and Derivatives …
Matched Categories: … Nicotinic Acid and Derivatives …
Diazoxide
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Description: … intravenously, diazoxide can be used to treat hypertensive emergencies;[L44622] however, this specific form ... and electrolyte disturbances. ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular …
Displaying drugs 101 - 125 of 215 in total