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Displaying drugs 176 - 200 of 4861 in total
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers ... N-butylidenephthalide, (e)+(z) …
Matched Categories: … Phthalic Acids ... Acids, Carbocyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. …
Matched Salts name: … Cefoxitin sodium
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Cefoxitin and Dextrose ... Cefoxitin for Injection ... Cefoxitin for Injection USP …
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in …
Matched Mixtures name: … Phineas and Ferb Sun Smacker SPF 24 Berry Busted ... Phineas and Ferb Sun Smacker SPF 24 Vanilla Vacation ... Aruba Aloe Lip Sunscreen and Moisturizer …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 …
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover ... Benzoyl peroxide is a commonly used drug in topical treatments for acne. …
Matched Mixtures name: … Unblemish Regimen for Acne and Post Acne Marks ... SPOTLESS Regimen for Acne, Blemishes and Breakouts ... SPOTLESS Regimen for Acne, Blemishes and Breakouts …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Anti-Acne Preparations for Topical Use …
Matched Products: … Spectro Acnecare Wash for Acne Prone Skin ... Solimo Renewing Cleanser For Acne Prone Skin ... Solimo Repairing Treatment For Acne Prone Skin …
Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … for management of different models of neuropathic pain [A32316]. ... pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied ... , nordihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin [A32318]. …
Matched Mixtures name: … Herbalax Forte No 70 Tab ... Half and Half Balm ... Hot Spice and Ice …
Matched Products: … Sheffield Arthritis and Muscle Pain Relief …
Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Synonyms: … Camphor D-form
Matched Description: … The FDA ruled that camphorated oil could not be marketed in the United States and that no product could ... It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often …
Matched Mixtures name: … Orajel for Codl Sores Relief and Concealer ... Premier Value Instant Antiseptic Pain Relief ... Super Forte Xl10 …
Matched Categories: … Antipruritics and Local Anesthetics ... Basic Lotions and Liniments …
Matched Products: … Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving ... Earths Care Muscle and Joint Rub …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … 3-(N-methylpyrollidino)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine ... (S)-3-(N-methylpyrrolidin-2-yl)pyridine …
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Up and Up Nicotine ... Up and Up Nicotine Polacrilex ... Berkley and Jensen Nicotine …
Investigational
Matched Synonyms: … specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and
Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Iupac: … propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-4-methylpentanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine …
Matched Description: … Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, ... downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing …
Matched Mixtures name: … Leuprolide Acetate ... Leuprolide Acetate ... Leuprolide Acetate
Matched Salts name: … Leuprolide acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... leuprorelin and bicalutamide …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. …
Matched Mixtures name: … Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sodium In 0.9% Sodium Chloride Injection …
Matched Salts name: … Heparin sodium
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars ... Heparins or Heparinoids for Topical Use …
Matched Products: … Heparin Sodium and Sodium Chloride ... Heparin Sodium and Dextrose ... Heparin Sodium in Sodium Chloride
Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Categories: … Increased Histamine Release …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows ... In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... NWI Artificial Tears Eye …
Matched Products: … Foster and Thrive Dry Eye Relief …
OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor …
Artemisia vulgaris pollen is the pollen of the Artemisia vulgaris plant. Artemisia vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release ... Non-Standardized Pollen Allergenic Extract …
Matched Products: … Pollens - Weeds and Garden Plants, Sagebrush, Mugwort Artemisia vulgaris …
Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... telomerase reverse transcriptase (hTERT) and IRES, respectively. ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …
Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …
AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … a HER2-directed CAR and secrete IL-15 ... Ex vivo expanded allogeneic cord blood-derived NK cells that have been genetically modified to express …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric ... AB-201 is a CAR-NK cell therapy targeted against HER2. …
OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells ... It is being investigated for the treatment of X-linked chronic granulomatous disease. …
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Approved
Vet approved
Matched Description: … Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous ... Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration …
Matched Mixtures name: … Threonate and Succinic Acid ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... Iron Polysaccharides Folic Acid DHA …
Matched Products: … Cosmofer 50mg/ml Solution for injection and for infusion ... FERRO 2000 SOLUTION FOR INJECTION …
The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … γ-amino-n-butyric acid ... piperidic acid ... 4-aminobutanoic acid
Matched Name: … gamma-Aminobutyric acid
Matched Iupac: … 4-aminobutanoic acid
Matched Salts name: … Gamma-Aminobutyric Acid Hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Gongjinhyang Qi and Jin Eye …
Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are ... separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus …
Pleospora tarda allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Increased Histamine Release ... Non-Standardized Fungal Allergenic Extract …
Matched Products: … Molds, Rusts and Smuts, Stemphylium botryosum …
Displaying drugs 176 - 200 of 4861 in total