Displaying drugs 26 - 50 of 9360 in total
Lecanemab
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … (HUMAN .BETA. ... 118-145-GONADOTROPIN, CHORIONIC (HUMAN .BETA. ... HUMAN GROWTH HORMONE-CARBOXY-TERMINAL PEPTIDE (CTP) OF THE BETA CHAIN OF HUMAN CHORIONIC GONADOTROPIN …
Matched Description: … Somatrogon is a long-acting recombinant human growth hormone. ... chorionic gonadotropin (hCG) to the N-terminus and C-terminus of human growth hormone. ... three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta chain of human …
Matched Categories: … Recombinant Human Growth Hormone …
Matched Description: … Somatrogon is a long-acting recombinant human growth hormone. ... chorionic gonadotropin (hCG) to the N-terminus and C-terminus of human growth hormone. ... three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal residues, from the beta chain of human …
Matched Categories: … Recombinant Human Growth Hormone …
Adenovirus type 7 vaccine live
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … clone encodes a modified human interleukin-2. ... Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Description: … clone encodes a modified human interleukin-2. ... Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy ... Velmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring human ... authorization by the European Commission in March 2018 under the market name Lamzede [L39754] as the first human …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy ... Velmanase alfa has an amino acid sequence of the monomeric protein identical to the naturally occurring human ... authorization by the European Commission in March 2018 under the market name Lamzede [L39754] as the first human …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase …
Menotropins
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Synonyms: … Human menopausal gonadotrophin …
Matched Categories: … human menopausal gonadotrophin …
Matched Categories: … human menopausal gonadotrophin …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … ) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JNJ-63483043 .LAMBDA ... IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN ... PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4) …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional …
Palifermin
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Description: … Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin ... 3-(alpha-(4'-Nitrophenyl)-beta-acetylethyl)-4-hydroxycoumarin ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Categories: … 4-Hydroxycoumarins …
Matched Products: … Sintrom 4 mg Tabletten …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Categories: … 4-Hydroxycoumarins …
Matched Products: … Sintrom 4 mg Tabletten …
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen
Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized …
Matched Description: … applied to the burn site and, as they contain metabolically active and viable cells, provide a variety of human …
Matched Description: … applied to the burn site and, as they contain metabolically active and viable cells, provide a variety of human …
Angiotensin II
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin …
Formestane
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-hydroxy-4-androstene-3,17-dione ... 4-Hydroxy-delta(4)-androstenedione ... 4-OH-A …
Matched Description: … Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity …
Matched Description: … Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity …
Lenvatinib
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, and 4; …
Matched Products: … เล็นวิมา (4 มิลลิกรัม) ... Lenvima 4 mg Hard Capsules …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, and 4; …
Matched Products: … เล็นวิมา (4 มิลลิกรัม) ... Lenvima 4 mg Hard Capsules …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Itraconazole
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-.DELTA. …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … FUNİT 100 MG KAPSÜL, 4 ADET ... CANDİSTAT 100 MG SERT KAPSÜL, 4 ADET ... ITRAXYL 100 MG MIKROPELLET KAPSUL, 4 ADET …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … FUNİT 100 MG KAPSÜL, 4 ADET ... CANDİSTAT 100 MG SERT KAPSÜL, 4 ADET ... ITRAXYL 100 MG MIKROPELLET KAPSUL, 4 ADET …
Monobenzone
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Synonyms: … 4-(Benzyloxy)phenol ... 4-Benzyloxyphenol ... 4-Benzyloxy-phenol …
Matched Iupac: … 4-(benzyloxy)phenol …
Matched Iupac: … 4-(benzyloxy)phenol …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … 4-amino-1-hydroxybutane-1,1-diphosphonic acid ... (4-amino-1-hydroxybutylidene)bisphosphonic acid ... (4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid) …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Products: … BONEX 70 MG TABLET, 4 ADET ... LENDO 35 MG TABLET, 4 ADET ... LENDO 70 MG TABLET, 4 ADET …
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid …
Matched Mixtures name: … ALENDRON-HEXAL 4 WO CAL D ... BONYL PLUS ORAL ÇÖZELTI ,4 FLAKON ... VEGABON PLUS D TABLET, 4 ADET …
Matched Products: … BONEX 70 MG TABLET, 4 ADET ... LENDO 35 MG TABLET, 4 ADET ... LENDO 70 MG TABLET, 4 ADET …
Allantoin
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Synonyms: … (2,5-Dioxo-4-imidazolidinyl)urea ... 2,5-Dioxo-4-imidazolidinyl-urea ... 4-ureido-2,5-imidazolidinedione …
Matched Iupac: … (2,5-dioxoimidazolidin-4-yl)urea …
Matched Description: … human diets [FDA Label]. ... In human muscle, urate is oxidized to allantoin during such exercise [FDA Label]. ... In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. …
Matched Mixtures name: … Hands First 4 in 1 …
Matched Products: … Miracle GYN (4 Tablets) …
Matched Iupac: … (2,5-dioxoimidazolidin-4-yl)urea …
Matched Description: … human diets [FDA Label]. ... In human muscle, urate is oxidized to allantoin during such exercise [FDA Label]. ... In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. …
Matched Mixtures name: … Hands First 4 in 1 …
Matched Products: … Miracle GYN (4 Tablets) …
Momelotinib
Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. First approved by the FDA on September 15, 2023, momelotinib is used to treat myelofibrosis. Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells,...
Approved
Investigational
Matched Synonyms: … N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE …
Matched Iupac: … N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide …
Matched Salts cas: … 1841094-17-4 …
Matched Iupac: … N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide …
Matched Salts cas: … 1841094-17-4 …
Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol ... 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab …
Matched Products: … เปอร์-4 ... โมนาซีน-4 ... โปราซิน 4 …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … โพลีบอน 4-10 ... PMS-levazine 4/25 Tab …
Matched Products: … เปอร์-4 ... โมนาซีน-4 ... โปราซิน 4 …
Fenbufen
Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 4-(4-Biphenylyl)-4-oxobutyric acid ... 3-(4-Phenylbenzoyl)propionic acid ... 3-(4-Biphenylylcarbonyl)propionic acid …
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
Sulfamerazine
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine ... 4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide ... 2-Sulfa-4-methylpyrimidine …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Displaying drugs 26 - 50 of 9360 in total