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Displaying drugs 51 - 75 of 308 in total
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically...
Approved
Investigational
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Description: … initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within the dorsal root
Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … initial infection of VZV and resolution of Chickenpox as a child, VZV then lies dormant within the dorsal root
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Approved
Experimental
Matched Synonyms: … Ginger root oil ... Ginger root oil china ... Ginger root oil cochin …
Matched Name: … Ginger oil
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Synonyms: … Betula pendula/pubescens bark
Matched Name: … Birch bark extract …
Matched Description: … sunflower oil) have been approved by the European Medicines Agency. ... [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species ... Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities …
Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Atractyloides Japonica Root Oil ... Atractylodes Lancea Rhizome Volatile Oil
Matched Name: … Atractylodes lancea root oil
Matched Description: … Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Anti-Cellulite Honzo Seika Chinese Herbal Aroma Oil
Approved
Experimental
Matched Synonyms: … Salix spp. bark
Matched Name: … Willow bark
Approved
Experimental
Matched Synonyms: … Senega officinalis root ... Senega officinalis ... Seneca snakeroot root
Matched Name: … Polygala senega root
Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Synonyms: … Artemisia officinalis root ... Mugwort root ... Felon-herb root
Matched Name: … Artemisia vulgaris root
Matched Description: … Artemisia vulgaris root allergenic extract is used in allergenic testing. …
Inula helenium root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Elf-dock Root ... Elf-wort Root ... Elecampane Root
Matched Name: … Inula helenium root
Matched Description: … Inula helenium root is a plant/plant extract used in some OTC (over-the-counter) products. …
The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn wound eschar debridement agent that has been approved by the EMA since 2012 and marketed under the brand name Nexobrid [FDA Label]. Bromelain itself belongs to a category of protein-digesting enzymes that are...
Approved
Investigational
Matched Synonyms: … Bromelain, stem ... Pineapple stem bromelain …
Matched Name: … Stem bromelain …
Matched Description: … , the general term bromelain typically refers to stem bromelain [A27198]. ... The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn ... belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem
Ginger allergenic extract is used in allergenic testing.
Approved
Matched Name: … Ginger
Matched Description: … Ginger allergenic extract is used in allergenic testing. …
Matched Products: … Ginger Root Cap ... Pain Relief Honzo Seika Chinese Herbal Aroma Oil ... Ginger
Approved
Experimental
Matched Synonyms: … Echinacea angustifolia root ... Echinacea angustifolia root extract ... Echinacea angustifolia, powdered …
Matched Name: … Echinacea angustifolia root
Elm is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Elm Bark ... Slippery Elm Inner Bark ... Ulmus Fulva Inner Bark
Turmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Curcuma Montana Root ... Yellow Ginger Root ... Ginger Yellow (Curcuma Longa) …
Matched Mixtures name: … Oil ... Turmeric Oil
Eleuthero is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Root ... Eleuthero Root ... Eleutherococcus Root
Puccinia graminis is a fungus which can provoke allergic reactions. Puccinia graminis extract is used in allergenic testing.
Approved
Matched Synonyms: … wheat stem rust extract …
Matched Products: … Wheat Stem Rust …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem
Matched Categories: … Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Displaying drugs 51 - 75 of 308 in total