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Displaying drugs 176 - 200 of 9781 in total
A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Approved
Matched Products: … Truemed Group LLC …
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. ... the survival of B cells. ... Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte …
Matched Categories: … Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen ... is not tumour-specific and can also be found in normal B-cells. ... Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. …
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Products: … CALCIO GLUCONATO B. BRAUN ... Calciumgluconat B. Braun 10 % Injektionslösung …
Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Mixtures name: … AMIGDAL-B® ... TROCILETAS B CEREZA ... Oral B Anti-bacterial With Fluoride …
Matched Products: … Oral-B Anti-Bacterial ... Oral-B Gum Therapy ... Oral B Gum Detoxify Special Care Rinse …
Approved
Matched Products: … Vivotif-B
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Description: … surface antigen B4. ... Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene ... [L31588] CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … Elliotts B ... Elliotts B
Matched Products: … B. ... Sol-cart B ... B. BRAUN 8.4% SODIUM BICARBONATE IV INFUSION BP (100ML) …
Teclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug...
Approved
Investigational
Matched Description: … cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. ... IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also...
Approved
Matched Products: … Truemed Group LLC …
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … lymphocytic leukemia (B-CLL). ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing …
The Moderna COVID-19 Vaccine (mRNA-1273) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel coronavirus, SARS-CoV-2, leading...
Approved
Investigational
Matched Description: … stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ... a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen ... found on the surface of normal and malignant B lymphocytes. ... FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however …
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … cholangiocarcinoma exhibited gene rearrangements resulting in oncogenic fibroblast growth factor 2 (FGFR2) fusion ... cholangiocarcinoma in previously treated adult patients with a fibroblast growth factor receptor 2 (FGFR2) gene fusion
Matched Categories: … Protein Kinase Inhibitors …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group
Matched Categories: … Membrane Transport Modulators …
Matched Products: … A-B VASK 5 ... A-B VASK 10 ... AMLOTENS B TABLET 5MG …
Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Products: … B. BRAUN WATER FOR INJECTION BP ... B. BRAUN WATER FOR INJECTIONS B.P. ... B. BRAUN WATER FOR INJECTIONS BP (20ML) …
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Products: … Truemed Group LLC ... Dom-metoprolol-B Tab 100mg ... Dom-metoprolol-B - Tab 50mg …
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … Oral-B Minute-Foam Orang-A-Tangy ... Oral B Anti-bacterial With Fluoride ... Oral-B Anti-bacterial With Fluoride …
Matched Products: … Oral Fusion Anticavity ... Oral-B Anticavity ... Oral-B Neutra-Foam Mint …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Mixtures name: … Elliotts B ... Elliotts B ... Ionosol B and Dextrose …
Matched Products: … B. BRAUN 50% GLUCOSE INJECTION BP ... B. BRAUN 5% GLUCOSE IV INFUSION BP ... B. BRAUN 20% GLUCOSE IV INFUSION BP …
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system. Although the indazole analogue benzydamine is a...
Approved
Matched Products: … B GARGLE SOLUTION 0.15% W/V …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers and autoimmune conditions.[A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity and ability to clear bound cells through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), mediated by...
Approved
Investigational
Matched Description: … CD20, an antigen expressed by various B and T cells, is an attractive therapeutic target in various cancers ... [A244210, A244215,A241045] Ublituximab was initially developed by LFB Group but was licensed to TG ... [A244195, A244200, A244205] Monoclonal antibodies for B cell depletion rely on their binding affinity …
Matched Categories: … Leukemia, Lymphocytic, Chronic, B-Cell, drug therapy …
Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells. The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody, such as...
Approved
Investigational
Matched Description: … [L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 ... leukemia (CLL) or aggressive B-cell lymphoma, have a high probability of relapse or recurrence after ... [A249320] The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody …
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell …
Displaying drugs 176 - 200 of 9781 in total