You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on DrugBank.
Identification
NameMetoprolol
Accession NumberDB00264  (APRD00208)
TypeSmall Molecule
GroupsApproved, Investigational
Description

Metoprolol is a cardioselective β1-adrenergic blocking agent used for acute myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. It may also be used for supraventricular and tachyarrhythmias and prophylaxis for migraine headaches. Metoprolol is structurally similar to bisoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At low doses, metoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with higher doses. Unlike propranolol and pindolol, metoprolol does not exhibit membrane-stabilizing or intrinsic sympathomimetic activity. Membrane-stabilizing effects are only observed at doses much higher than those needed for β-adrenergic blocking activity. Metoprolol possesses a single chiral centre and is administered as a racemic mixture.

Structure
Thumb
Synonyms
SynonymLanguageCode
(RS)-MetoprololNot AvailableNot Available
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-olNot AvailableNot Available
MetoprololNot AvailableNot Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Lopressorinjection, solution5 mg/5mLintravenousNovartis Pharmaceuticals Corporation1978-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Lopressortablet50 mgoralNovartis Pharmaceuticals Corporation1978-01-152016-08-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Lopressortablet100 mgoralNovartis Pharmaceuticals Corporation1978-01-152016-09-30Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 25 mg/1; mgoralAstra Zeneca Lp2011-09-16Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 50 mg/1; mgoralAstra Zeneca Lp2011-09-16Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 100 mg/1; mgoralAstra Zeneca Lp2011-09-16Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 25 mg/1; mgoralAstra Zeneca Pharmaceuticals Lp2011-12-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 50 mg/1; mgoralAstra Zeneca Pharmaceuticals Lp2011-12-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet, film coated12.5; 100 mg/1; mgoralAstra Zeneca Pharmaceuticals Lp2011-12-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet12.5; 25 mg/1; mgoralCovis Pharmaceuticals Inc2014-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet12.5; 50 mg/1; mgoralCovis Pharmaceuticals Inc2014-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Dutoproltablet12.5; 100 mg/1; mgoralCovis Pharmaceuticals Inc2014-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Lopressortablet50 mgoralValidus Pharmaceuticals LLC2014-05-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Lopressortablet100 mgoralValidus Pharmaceuticals LLC2014-05-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralPd Rx Pharmaceuticals, Inc.2011-07-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralPd Rx Pharmaceuticals, Inc.2011-07-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralPar Pharmaceutical Inc.2006-11-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralPar Pharmaceutical Inc.2007-08-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralPar Pharmaceutical Inc.2007-07-26Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release200 mgoralPar Pharmaceutical Inc.2007-07-26Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralREMEDYREPACK INC.2013-03-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralREMEDYREPACK INC.2013-03-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralClinical Solutions Wholesale2007-08-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Metoprolol Tartratetablet, film coated50 mgoralTeva Pharmaceuticals USA Inc1995-04-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralTeva Pharmaceuticals USA Inc1995-04-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousWest ward Pharmaceutical Corp2007-05-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousWest ward Pharmaceutical Corp2007-05-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralMylan Pharmaceuticals Inc.2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralMylan Pharmaceuticals Inc.2012-05-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralMylan Pharmaceuticals Inc.2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralMylan Pharmaceuticals Inc.2012-05-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralMylan Pharmaceuticals Inc.2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralMylan Pharmaceuticals Inc.2012-05-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralMylan Pharmaceuticals Inc.2011-12-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralMylan Pharmaceuticals Inc.2011-12-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralMylan Pharmaceuticals Inc.2011-12-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralMylan Pharmaceuticals Inc.2011-12-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousHospira, Inc.1993-12-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousHospira, Inc.2008-04-29Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousHospira, Inc.1998-07-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousAmerican Regent, Inc.2010-02-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralActavis Pharma, Inc.1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralActavis Pharma, Inc.1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-05-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralSandoz Inc1994-03-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralSandoz Inc1994-03-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousSandoz Inc2007-10-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralMajor Pharmaceuticals2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralMajor Pharmaceuticals2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralMajor Pharmaceuticals2010-05-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralMajor Pharmaceuticals2010-10-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralMajor Pharmaceuticals2010-10-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralMajor Pharmaceuticals2010-10-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralMajor Pharmaceuticals2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralMajor Pharmaceuticals2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralMajor Pharmaceuticals2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralMajor Pharmaceuticals2013-08-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralMajor Pharmaceuticals2013-08-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralMajor Pharmaceuticals2013-08-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralBlenheim Pharmacal, Inc.2013-07-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralBlenheim Pharmacal, Inc.2013-10-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralAurolife Pharma LLC2010-09-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralAurolife Pharma LLC2010-09-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAurolife Pharma LLC2010-09-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralSTAT Rx USA LLC1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralRebel Distributors Corp.1996-12-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralRebel Distributors Corp.1996-12-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralRebel Distributors Corp.2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralRebel Distributors Corp2009-08-03Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralRebel Distributors Corp2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2013-03-19Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralREMEDYREPACK INC.2013-05-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralREMEDYREPACK INC.2013-03-18Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprololinjection5 mg/5mLintravenousSagent Pharmaceuticals2010-05-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAidarex Pharmaceuticals LLC1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralAidarex Pharmaceuticals LLC2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralLake Erie Medical DBA Quality Care Products LLC1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralLake Erie Medical DBA Quality Care Products LLC2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralLake Erie Medical DBA Quality Care Products LLC1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralLake Erie Medical DBA Quality Care Products LLC2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralLake Erie Medical DBA Quality Care Products LLC2009-08-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprololinjection5 mg/5mLintravenousClaris Lifesciences Inc.2012-09-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralPd Rx Pharmaceuticals, Inc.1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralPd Rx Pharmaceuticals, Inc.2011-05-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralAphena Pharma Solutions Tennessee, Llc2009-08-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralAphena Pharma Solutions Tennessee, Llc2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralAphena Pharma Solutions Tennessee, Llc2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralAphena Pharma Solutions Tennessee, Llc2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAphena Pharma Solutions Tennessee, Llc2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralAlembic Pharmaceuticals Limited2013-04-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralAlembic Pharmaceuticals Limited2013-04-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralAlembic Pharmaceuticals Limited2013-04-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralSafecor Health, LLC2014-09-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralSafecor Health, LLC2014-09-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralREMEDYREPACK INC.2011-04-19Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2011-04-19Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2013-06-03Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2013-07-26Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2011-07-07Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2013-07-29Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralREMEDYREPACK INC.2011-11-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralREMEDYREPACK INC.2013-07-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralREMEDYREPACK INC.2011-12-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralRubicon Research Private Limited2014-11-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralRubicon Research Private Limited2014-11-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralRubicon Research Private Limited2014-11-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralLake Erie Medical DBA Quality Care Products LLC2011-01-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2012-03-16Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralUnit Dose Services2009-03-24Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralUnit Dose Services2009-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralUnit Dose Services1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralUnit Dose Services2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralUnit Dose Services2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralUnit Dose Services2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralIngenus Pharmaceuticals, LLC2011-05-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralIngenus Pharmaceuticals, LLC2011-05-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralIngenus Pharmaceuticals, LLC2011-05-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralMylan Institutional Inc.2012-09-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralMylan Institutional Inc.2012-09-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralMylan Institutional Inc.2012-09-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralMylan Institutional Inc.2012-08-31Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralMylan Institutional Inc.2012-08-31Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralMylan Institutional Inc.2012-08-31Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralMed Health Pharma, LLC2011-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralMed Health Pharma, LLC2011-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralMed Health Pharma, LLC2011-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralMed Health Pharma, LLC2011-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralNorthwind Pharmaceuticals, LLC2014-09-19Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mg/301oralNorthwind Pharmaceuticals2014-05-07Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mg/301oralNorthwind Pharmaceuticals2014-05-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralNorthwind Pharmaceuticals, LLC2014-09-12Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2013-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2013-03-20Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralREMEDYREPACK INC.2013-03-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralREMEDYREPACK INC.2013-06-17Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralREMEDYREPACK INC.2013-05-07Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2013-05-07Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2013-05-23Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2014-10-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralREMEDYREPACK INC.2013-05-24Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralREMEDYREPACK INC.2014-02-20Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralREMEDYREPACK INC.2014-04-24Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralREMEDYREPACK INC.2014-08-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralGen Source Rx2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralGen Source Rx2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralGen Source Rx2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousGeneral Injectables & Vaccines, Inc2010-08-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralState of Florida DOH Central Pharmacy2014-11-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralState of Florida DOH Central Pharmacy2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralState of Florida DOH Central Pharmacy2014-11-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralInternational Labs, Inc.2011-09-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralInternational Labs, Inc.2011-09-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralInternational Labs, Inc.2011-09-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralPhysicians Total Care, Inc.1994-01-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralPhysicians Total Care, Inc.1994-11-29Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralPhysicians Total Care, Inc.2004-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousPhysicians Total Care, Inc.2006-12-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralPhysicians Total Care, Inc.2008-02-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralPhysicians Total Care, Inc.2007-08-03Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralPhysicians Total Care, Inc.2010-01-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralPhysicians Total Care, Inc.2007-07-31Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralDr. Reddy's Laboratories Limited2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralDr. Reddy's Laboratories Limited2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralDr. Reddy's Laboratories Limited2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release200 mgoralDr. Reddy's Laboratories Limited2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousCardinal Health2008-05-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCardinal Health2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralCardinal Health2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralCardinal Health2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralCardinal Health2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousCardinal Health1998-07-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralCardinal Health2010-10-05Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralCardinal Health1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralCardinal Health1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralCardinal Health2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralCardinal Health1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousCardinal Health1998-07-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousCardinal Health2008-04-29Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCardinal Health2010-06-09Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralCardinal Health2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCardinal Health2013-07-23Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralCardinal Health2014-03-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralCardinal Health2014-03-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCardinal Health2011-01-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralCardinal Health2011-01-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCardinal Health2011-01-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution1 mg/mLintravenousCardinal Health2010-02-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCardinal Health2010-01-12Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCardinal Health2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCardinal Health2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousCardinal Health2007-05-30Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralPd Rx Pharmaceuticals, Inc.1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralPd Rx Pharmaceuticals, Inc.2011-05-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralPd Rx Pharmaceuticals, Inc.1994-05-27Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection, solution5 mg/5mLintravenousBedford Laboratories2003-07-172015-03-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralWockhardt Limited2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralWockhardt Limited2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralWockhardt Limited2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralWockhardt Limited2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCitron Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCitron Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralCitron Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralCaraco Pharmaceutical Laboratories, Ltd.1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralCaraco Pharmaceutical Laboratories, Ltd.1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralCaraco Pharmaceutical Laboratories, Ltd.1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralCaraco Pharmaceutical Laboratories, Ltd.1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralCaraco Pharmaceutical Laboratories, Ltd.2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralClinical Solutions Wholesale1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralClinical Solutions Wholesale1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralClinical Solutions Wholesale1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralClinical Solutions Wholesale2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralClinical Solutions Wholesale2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinate extended-releasetablet, film coated, extended release23.75 mgoralEthex Corporation2009-11-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralNew Horizon Rx Group, LLC2013-08-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralGreenstone LLC2007-09-112015-02-28Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralGreenstone LLC2007-09-112016-03-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralGreenstone LLC2007-09-112015-10-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralGolden State Medical Supply, Inc.2013-03-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralGolden State Medical Supply, Inc.2013-03-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralGolden State Medical Supply, Inc.2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release200 mgoralGolden State Medical Supply, Inc.2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralSt Marys Medical Park Pharmacy2014-04-21Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralSt Marys Medical Park Pharmacy2013-05-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralSt Marys Medical Park Pharmacy2013-05-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralSt Marys Medical Park Pharmacy2013-08-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralSt Marys Medical Park Pharmacy2013-08-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralSt Marys Medical Park Pharmacy2013-08-08Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralDIRECT RX2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralDIRECT RX2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralWatson Pharma, Inc.2009-08-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralWatson Pharma, Inc.2009-08-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralWatson Pharma, Inc.2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralWatson Pharma, Inc.2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralAmerican Health Packaging2010-06-09Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralAmerican Health Packaging2010-06-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAmerican Health Packaging2010-07-26Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralProficient Rx LP2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralProficient Rx LP2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralRanbaxy Pharmaceuticals Inc.2009-03-24Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralRanbaxy Pharmaceuticals Inc.2009-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralRanbaxy Pharmaceuticals Inc.2009-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprololinjection, solution5 mg/5mLintravenousFresenius Kabi USA, LLC2010-10-28Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralbryant ranch prepack2009-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralbryant ranch prepack2009-03-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralbryant ranch prepack2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralbryant ranch prepack2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralbryant ranch prepack2010-04-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralbryant ranch prepack2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2011-02-02Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralWockhardt USA LLC.2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralWockhardt USA LLC.2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralWockhardt USA LLC.2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralWockhardt USA LLC.2010-07-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralTYA Pharmaceuticals1997-07-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralTYA Pharmaceuticals2009-03-24Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralAurobindo Pharma Limited2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralAurobindo Pharma Limited2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAurobindo Pharma Limited2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralMed Vantx, Inc.1995-04-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralContract Pharmacy Services Pa2011-01-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralContract Pharmacy Services Pa2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralContract Pharmacy Services Pa2009-06-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralAphena Pharma Solutions Tennessee, Llc2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralAphena Pharma Solutions Tennessee, Llc2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralAphena Pharma Solutions Tennessee, Llc2013-04-22Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralBlue Point Laboratories2013-11-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release200 mgoralBlue Point Laboratories2013-11-25Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralBlue Point Laboratories2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralBlue Point Laboratories2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartrateinjection5 mg/5mLintravenousGland Pharma Limited2014-10-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release100 mgoralAmerican Health Packaging2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release200 mgoralAmerican Health Packaging2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release25 mgoralAmerican Health Packaging2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, film coated, extended release50 mgoralAmerican Health Packaging2010-08-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralAmerican Health Packaging2014-03-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralAmerican Health Packaging2014-03-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralAmerican Health Packaging2014-05-12Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralCarilion Materials Management2014-01-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralDispensing Solutions, Inc.2009-08-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralDispensing Solutions, Inc.2004-01-15Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralLegacy Pharmaceutical Packaging2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralLegacy Pharmaceutical Packaging2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release25 mgoralLegacy Pharmaceutical Packaging2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release50 mgoralLegacy Pharmaceutical Packaging2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Succinatetablet, extended release100 mgoralLegacy Pharmaceutical Packaging2012-09-10Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet25 mgoralPreferred Pharmaceuticals, Inc.2015-01-13Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralPreferred Pharmaceuticals, Inc.2013-04-01Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralPreferred Pharmaceuticals, Inc.2012-02-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralPreferred Pharmaceuticals, Inc.2012-02-14Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralCronus Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated50 mgoralCronus Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated100 mgoralCronus Pharma LLC2007-09-11Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet, film coated25 mgoralMc Kesson Contract Packaging2011-10-06Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet50 mgoralMc Kesson Contract Packaging2011-10-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprolol Tartratetablet100 mgoralMc Kesson Contract Packaging2011-11-04Not AvailableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Metoprololtablet50 mgoralSanis Health IncNot AvailableNot AvailableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Metoprololtablet100 mgoralSanis Health IncNot AvailableNot AvailableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Over the Counter ProductsNot Available
International Brands
NameCompany
CorvitolNot Available
MinaxNot Available
SelokeenNot Available
TOPROLNot Available
Toprol-XLNot Available
TOPROLXLNot Available
Brand mixturesNot Available
Salts
Name/CASStructureProperties
Metoprolol succinate
ThumbNot applicableDBSALT000863
Metoprolol tartrate
ThumbNot applicableDBSALT000862
Categories
CAS number37350-58-6
WeightAverage: 267.3639
Monoisotopic: 267.183443671
Chemical FormulaC15H25NO3
InChI KeyIUBSYMUCCVWXPE-UHFFFAOYSA-N
InChI
InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3
IUPAC Name
1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol
SMILES
COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as tyrosols and derivatives. These are compounds containing a hydroxyethyl group attached to the C4 carbon of a phenol group.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassPhenols and derivatives
Direct ParentTyrosols and derivatives
Alternative Parents
Substituents
  • Tyrosol derivative
  • Phenol ether
  • Alkyl aryl ether
  • Secondary alcohol
  • 1,2-aminoalcohol
  • Secondary amine
  • Ether
  • Secondary aliphatic amine
  • Dialkyl ether
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Amine
  • Alcohol
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External DescriptorsNot Available
Pharmacology
IndicationFor the management of acute myocardial infarction, angina pectoris, heart failure and mild to moderate hypertension. May be used to treat supraventricular and tachyarrhythmias and as prophylaxis for migraine headaches.
PharmacodynamicsMetoprolol, a competitive, beta1-selective (cardioselective) adrenergic antagonist, is similar to atenolol in its moderate lipid solubility, lack of intrinsic sympathomimetic activity (ISA), and weak membrane stabilizing activity (MSA).
Mechanism of actionMetoprolol competes with adrenergic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart. Beta(1)-receptor blockade results in a decrease in heart rate, cardiac output, and blood pressure.
AbsorptionRapid and complete, 50%
Volume of distributionNot Available
Protein binding12%
Metabolism

Primarily hepatic

SubstrateEnzymesProduct
Metoprolol
alpha-HydroxymetoprololDetails
Route of eliminationLess than 5% of an oral dose of metoprolol is recovered unchanged in the urine; the rest is excreted by the kidneys as metabolites that appear to have no beta-blocking activity.
Half life3-7 hours
ClearanceNot Available
ToxicityLD50=5500 mg/kg (orally in rats), toxic effects include bradycardia, hypotension, bronchospasm, and cardiac failure. LD50=2090 mg/kg (orally in mice)
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Metoprolol Action PathwayDrug actionSMP00302
SNP Mediated Effects
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeEffectReference(s)
Beta-1 adrenergic receptor
Gene symbol: ADRB1
UniProt: P08588
rs1801253 Not AvailableC AlleleImproved response to blood pressure medication12844134
Beta-1 adrenergic receptor
Gene symbol: ADRB1
UniProt: P08588
rs1801252 Not AvailableA AlleleImproved response to blood pressure medication12844134
Beta-1 adrenergic receptor
Gene symbol: ADRB1
UniProt: P08588
rs1801253 Not AvailableG > CBetter response to drug therapy12844134
SNP Mediated Adverse Drug Reactions
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeAdverse ReactionReference(s)
Cytochrome P450 2D6
Gene symbol: CYP2D6
UniProt: P10635
rs3892097 CYP2D6*4A alleleIncreased risk of slow heart rate (bradycardia)18784654
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9854
Blood Brain Barrier-0.8426
Caco-2 permeable+0.6895
P-glycoprotein substrateSubstrate0.7317
P-glycoprotein inhibitor INon-inhibitor0.8182
P-glycoprotein inhibitor IINon-inhibitor0.8382
Renal organic cation transporterNon-inhibitor0.8418
CYP450 2C9 substrateNon-substrate0.81
CYP450 2D6 substrateSubstrate0.8918
CYP450 3A4 substrateNon-substrate0.6527
CYP450 1A2 substrateNon-inhibitor0.7018
CYP450 2C9 substrateNon-inhibitor0.8691
CYP450 2D6 substrateNon-inhibitor0.7909
CYP450 2C19 substrateNon-inhibitor0.9555
CYP450 3A4 substrateNon-inhibitor0.9476
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9897
Ames testNon AMES toxic0.9163
CarcinogenicityNon-carcinogens0.9387
BiodegradationNot ready biodegradable0.8544
Rat acute toxicity1.9180 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.8368
hERG inhibition (predictor II)Non-inhibitor0.8202
Pharmacoeconomics
Manufacturers
  • Novartis pharmaceuticals corp
  • Kv pharmaceutical co
  • Sandoz inc
  • Watson laboratories inc florida
  • Wockhardt ltd
  • Astrazeneca lp
  • Bedford laboratories
  • Hikma farmaceutica (portugal) sa
  • Hospira inc
  • Luitpold pharmaceuticals inc
  • Sagent strides llc
  • Sandoz canada inc
  • Watson laboratories inc
  • Apothecon inc div bristol myers squibb
  • Aurobindo pharma ltd
  • Caraco pharmaceutical laboratories ltd
  • Ipca laboratories ltd
  • Mutual pharmaceutical co inc
  • Mylan pharmaceuticals inc
  • Purepac pharmaceutical co
  • Solco healthcare us llc
  • Teva pharmaceuticals usa inc
  • Teva pharmaceuticals usa
Packagers
Dosage forms
FormRouteStrength
Injectionintravenous5 mg/5mL
Injection, solutionintravenous1 mg/mL
Injection, solutionintravenous5 mg/5mL
Tabletoral100 mg
Tabletoral12.5; 100 mg/1; mg
Tabletoral12.5; 25 mg/1; mg
Tabletoral12.5; 50 mg/1; mg
Tabletoral25 mg
Tabletoral50 mg
Tablet, extended releaseoral100 mg
Tablet, extended releaseoral200 mg
Tablet, extended releaseoral25 mg
Tablet, extended releaseoral50 mg
Tablet, film coatedoral100 mg
Tablet, film coatedoral12.5; 100 mg/1; mg
Tablet, film coatedoral12.5; 25 mg/1; mg
Tablet, film coatedoral12.5; 50 mg/1; mg
Tablet, film coatedoral25 mg
Tablet, film coatedoral50 mg
Tablet, film coated, extended releaseoral100 mg
Tablet, film coated, extended releaseoral200 mg
Tablet, film coated, extended releaseoral23.75 mg
Tablet, film coated, extended releaseoral25 mg
Tablet, film coated, extended releaseoral25 mg/301
Tablet, film coated, extended releaseoral50 mg
Tablet, film coated, extended releaseoral50 mg/301
Prices
Unit descriptionCostUnit
Metoprolol tartrate powder5.51USD g
Lopressor 5 mg/5 ml ampul3.85USD ml
Lopressor hct 100-25 tablet3.21USD tablet
Toprol XL 200 mg 24 Hour tablet3.08USD tablet
Lopressor HCT 100-50 mg tablet3.06USD tablet
Toprol xl 200 mg tablet2.96USD tablet
Lopressor hct 100-50 tablet2.82USD tablet
Lopressor 100 mg tablet2.75USD tablet
Metoprolol Succinate 200 mg 24 Hour tablet2.62USD tablet
Metoprolol succ er 200 mg tablet2.29USD tablet
Lopressor HCT 100-25 mg tablet2.21USD tablet
Lopressor HCT 50-25 mg tablet2.14USD tablet
Lopressor hct 50-25 tablet2.06USD tablet
Toprol XL 100 mg 24 Hour tablet1.93USD tablet
Toprol xl 100 mg tablet1.86USD tablet
Lopressor 50 mg tablet1.81USD tablet
Metoprolol Succinate 100 mg 24 Hour tablet1.53USD tablet
Metoprolol succ er 100 mg tablet1.44USD tablet
Toprol XL 25 mg 24 Hour tablet1.43USD tablet
Toprol XL 50 mg 24 Hour tablet1.43USD tablet
Lopresor 1 mg/ml1.29USD ml
Toprol xl 25 mg tablet1.24USD tablet
Toprol xl 50 mg tablet1.24USD tablet
Metoprolol Succinate 25 mg 24 Hour tablet1.17USD tablet
Metoprolol Succinate 50 mg 24 Hour tablet1.13USD tablet
Metoprolol succ er 50 mg tablet0.9USD tablet
Metoprolol succ er 25 mg tablet0.87USD tablet
Metoprolol tartrate 100 mg tablet0.8USD tablet
Toprol xl 100 mg tablet sa0.8USD tablet
Lopresor 100 mg Tablet0.61USD tablet
Lopresor Sr 200 mg Sustained-Release Tablet0.61USD tablet
Metoprolol tartrate 50 mg tablet0.56USD tablet
Metoprolol tartrate 25 mg tablet0.34USD tablet
Apo-Metoprolol Sr 200 mg Sustained-Release Tablet0.34USD tablet
Lopresor Sr 100 mg Sustained-Release Tablet0.34USD tablet
Sandoz Metoprolol Sr 200 mg Sustained-Release Tablet0.34USD tablet
Lopresor 50 mg Tablet0.3USD tablet
Apo-Metoprolol (Type L) 100 mg Tablet0.23USD tablet
Apo-Metoprolol 100 mg Tablet0.23USD tablet
Mylan-Metoprolol (Type L) 100 mg Tablet0.23USD tablet
Novo-Metoprol (Fc) 100 mg Tablet0.23USD tablet
Novo-Metoprol 100 mg Tablet0.23USD tablet
Nu-Metop 100 mg Tablet0.23USD tablet
Pms-Metoprolol-L 100 mg Tablet0.23USD tablet
Sandoz Metoprolol (Type L) 100 mg Tablet0.23USD tablet
Apo-Metoprolol Sr 100 mg Sustained-Release Tablet0.19USD tablet
Sandoz Metoprolol Sr 100 mg Sustained-Release Tablet0.19USD tablet
Apo-Metoprolol (Type L) 50 mg Tablet0.13USD tablet
Apo-Metoprolol 50 mg Tablet0.13USD tablet
Mylan-Metoprolol (Type L) 50 mg Tablet0.13USD tablet
Novo-Metoprol (Fc) 50 mg Tablet0.13USD tablet
Novo-Metoprol 50 mg Tablet0.13USD tablet
Nu-Metop 50 mg Tablet0.13USD tablet
Pms-Metoprolol-L 50 mg Tablet0.13USD tablet
Sandoz Metoprolol (Type L) 50 mg Tablet0.13USD tablet
Apo-Metoprolol 25 mg Tablet0.07USD tablet
Pms-Metoprolol-L 25 mg Tablet0.07USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point120 °C (tartarate salt)Not Available
water solubility1.69E+004 mg/L (at 25 °C)MCFARLAND,JW ET AL. (2001)
logP1.88HANSCH,C ET AL. (1995)
Caco2 permeability-4.59ADME Research, USCD
Predicted Properties
PropertyValueSource
Water Solubility0.402 mg/mLALOGPS
logP1.8ALOGPS
logP1.76ChemAxon
logS-2.8ALOGPS
pKa (Strongest Acidic)14.09ChemAxon
pKa (Strongest Basic)9.67ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area50.72 Å2ChemAxon
Rotatable Bond Count9ChemAxon
Refractivity76.7 m3·mol-1ChemAxon
Polarizability31.9 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraMS/MS1D NMR2D NMR
References
Synthesis Reference

DrugSyn.org

US3998790
General Reference
  1. : Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) Lancet. 1999 Jun 12;353(9169):2001-7. Pubmed
External Links
ATC CodesC07AB02
AHFS Codes
  • 24:24.00
PDB EntriesNot Available
FDA labelDownload (439 KB)
MSDSDownload (73.9 KB)
Interactions
Drug Interactions
Drug
AbirateroneCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
AcetylcholineBeta-Blockers may enhance the adverse/toxic effect of Cholinergic Agonists. Of particular concern are the potential for cardiac conduction abnormalities and bronchoconstriction.
AmifostineAntihypertensives may enhance the hypotensive effect of Amifostine.
AmiodaroneCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
AripiprazoleCYP2D6 Inhibitors (Weak) may increase the serum concentration of ARIPiprazole.
ArtemetherCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
BretyliumMay enhance the bradycardic effect of Bradycardia-Causing Agents. Bretylium may also enhance atrioventricular (AV) blockade in patients receiving AV blocking agents.
BupivacaineBeta-Blockers may increase the serum concentration of Bupivacaine.
BupropionCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ButabarbitalMay decrease the serum concentration of Beta-Blockers.
ButethalMay decrease the serum concentration of Beta-Blockers.
CarbacholBeta-Blockers may enhance the adverse/toxic effect of Cholinergic Agonists. Of particular concern are the potential for cardiac conduction abnormalities and bronchoconstriction.
CelecoxibCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ChloroquineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ChlorpromazineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
CimetidineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
CinacalcetCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ClobazamCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ClomipramineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ClozapineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
CocaineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
DarifenacinCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
DarunavirMay increase the serum concentration of CYP2D6 Substrates.
DelavirdineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
DesipramineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
DiazoxideMay enhance the hypotensive effect of Antihypertensives.
DipyridamoleMay enhance the bradycardic effect of Beta-Blockers.
DisopyramideMay enhance the bradycardic effect of Beta-Blockers. Beta-Blockers may enhance the negative inotropic effect of Disopyramide.
DronedaroneMay enhance the bradycardic effect of Beta-Blockers. Dronedarone may increase the serum concentration of Beta-Blockers. This likely applies only to those agents that are metabolized by CYP2D6.
DuloxetineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
EliglustatCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
FingolimodBeta-Blockers may enhance the bradycardic effect of Fingolimod.
FloctafenineMay enhance the adverse/toxic effect of Beta-Blockers.
FluoxetineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
HaloperidolCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
HeptabarbitalMay decrease the serum concentration of Beta-Blockers.
HexobarbitalMay decrease the serum concentration of Beta-Blockers.
ImipramineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
IsoniazidCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
LacosamideBradycardia-Causing Agents may enhance the AV-blocking effect of Lacosamide.
LercanidipineMay enhance the hypotensive effect of Metoprolol. Metoprolol may decrease the serum concentration of Lercanidipine.
LopinavirCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
LorcaserinCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
LumefantrineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
MepivacaineBeta-Blockers may increase the serum concentration of Mepivacaine.
MethacholineBeta-Blockers may enhance the adverse/toxic effect of Methacholine.
MethadoneCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
MethohexitalMay decrease the serum concentration of Beta-Blockers.
MethotrimeprazineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
MethylphenidateMay diminish the antihypertensive effect of Antihypertensives.
MidodrineBeta-Blockers may enhance the bradycardic effect of Midodrine.
MirabegronMay diminish the antihypertensive effect of Metoprolol. Mirabegron may increase the serum concentration of Metoprolol.
NilotinibCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
ObinutuzumabAntihypertensives may enhance the hypotensive effect of Obinutuzumab.
PanobinostatMay increase the serum concentration of CYP2D6 Substrates.
ParoxetineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
Peginterferon alfa-2bMay decrease the serum concentration of CYP2D6 Substrates. Peginterferon Alfa-2b may increase the serum concentration of CYP2D6 Substrates.
PentobarbitalMay decrease the serum concentration of Beta-Blockers.
PentoxifyllineMay enhance the hypotensive effect of Antihypertensives.
PrimidoneMay decrease the serum concentration of Beta-Blockers.
PromazineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
PropafenoneMay increase the serum concentration of Beta-Blockers. Propafenone possesses some independent beta blocking activity.
QuinidineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
QuinineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
RegorafenibMay enhance the bradycardic effect of Beta-Blockers.
ReserpineMay enhance the hypotensive effect of Beta-Blockers.
RisperidoneHypotensive Agents may enhance the hypotensive effect of RisperiDONE.
RitonavirCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
RituximabAntihypertensives may enhance the hypotensive effect of RiTUXimab.
RivastigmineMay enhance the bradycardic effect of Beta-Blockers.
RuxolitinibMay enhance the bradycardic effect of Bradycardia-Causing Agents.
SecobarbitalMay decrease the serum concentration of Beta-Blockers.
SertralineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
TadalafilMay enhance the antihypertensive effect of Antihypertensives.
ThioridazineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
TiclopidineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
TipranavirCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
TofacitinibMay enhance the bradycardic effect of Bradycardia-Causing Agents.
TranylcypromineCYP2D6 Inhibitors may increase the serum concentration of Metoprolol.
VardenafilMay enhance the antihypertensive effect of Antihypertensives.
YohimbineMay diminish the antihypertensive effect of Antihypertensives.
Food Interactions
  • Avoid alcohol.
  • Avoid natural licorice.
  • Take with food.

Targets

1. Beta-1 adrenergic receptor

Kind: protein

Organism: Human

Pharmacological action: yes

Actions: antagonist

Components

Name UniProt ID Details
Beta-1 adrenergic receptor P08588 Details

References:

  1. Schafer M, Frischkopf K, Taimor G, Piper HM, Schluter KD: Hypertrophic effect of selective beta(1)-adrenoceptor stimulation on ventricular cardiomyocytes from adult rat. Am J Physiol Cell Physiol. 2000 Aug;279(2):C495-503. Pubmed
  2. Staudt A, Mobini R, Fu M, Grosse Y, Stangl V, Stangl K, Thiele A, Baumann G, Felix SB: beta(1)-Adrenoceptor antibodies induce positive inotropic response in isolated cardiomyocytes. Eur J Pharmacol. 2001 Jul 6;423(2-3):115-9. Pubmed
  3. Staudt Y, Mobini R, Fu M, Felix SB, Kuhn JP, Staudt A: Beta1-adrenoceptor antibodies induce apoptosis in adult isolated cardiomyocytes. Eur J Pharmacol. 2003 Apr 11;466(1-2):1-6. Pubmed
  4. Johnson JA, Zineh I, Puckett BJ, McGorray SP, Yarandi HN, Pauly DF: Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol. Clin Pharmacol Ther. 2003 Jul;74(1):44-52. Pubmed
  5. Liu J, Liu ZQ, Tan ZR, Chen XP, Wang LS, Zhou G, Zhou HH: Gly389Arg polymorphism of beta1-adrenergic receptor is associated with the cardiovascular response to metoprolol. Clin Pharmacol Ther. 2003 Oct;74(4):372-9. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

2. Beta-2 adrenergic receptor

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: antagonist

Components

Name UniProt ID Details
Beta-2 adrenergic receptor P07550 Details

References:

  1. Zebrack JS, Munger M, Macgregor J, Lombardi WL, Stoddard GP, Gilbert EM: Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. Pharmacotherapy. 2009 Aug;29(8):883-90. Pubmed

Enzymes

1. Cytochrome P450 2D6

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Cytochrome P450 2D6 P10635 Details

References:

  1. Flockhart DA. Drug Interactions: Cytochrome P450 Drug Interaction Table. Indiana University School of Medicine (2007). Accessed May 28, 2010.
  2. Belpaire FM, Wijnant P, Temmerman A, Rasmussen BB, Brosen K: The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors. Eur J Clin Pharmacol. 1998 May;54(3):261-4. Pubmed
  3. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed
  4. Lexicomp

2. Cytochrome P450 2C19

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Cytochrome P450 2C19 P33261 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

Transporters

1. Solute carrier family 22 member 2

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: inhibitor

Components

Name UniProt ID Details
Solute carrier family 22 member 2 O15244 Details

References:

  1. Dudley AJ, Bleasby K, Brown CD: The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK cell monolayers. Br J Pharmacol. 2000 Sep;131(1):71-9. Pubmed

2. Multidrug resistance protein 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Multidrug resistance protein 1 P08183 Details

References:

  1. Takara K, Kakumoto M, Tanigawara Y, Funakoshi J, Sakaeda T, Okumura K: Interaction of digoxin with antihypertensive drugs via MDR1. Life Sci. 2002 Feb 15;70(13):1491-500. Pubmed
  2. Doppenschmitt S, Langguth P, Regardh CG, Andersson TB, Hilgendorf C, Spahn-Langguth H: Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay. J Pharmacol Exp Ther. 1999 Jan;288(1):348-57. Pubmed
  3. Neuhoff S, Ungell AL, Zamora I, Artursson P: pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions. Pharm Res. 2003 Aug;20(8):1141-8. Pubmed

Comments
comments powered by Disqus
Drug created on June 13, 2005 07:24 / Updated on October 08, 2013 14:24