Nerve Tissue Proteins

Name
Nerve Tissue Proteins
Accession Number
DBCAT000059
Description
Not Available
Drugs
DrugDrug Description
LeuprolideA protein-based luteinizing hormone agonist used to treat prostate cancer, endometriosis, and precocious puberty.
SermorelinFor the treatment of dwarfism, prevention of HIV-induced weight loss
GoserelinA synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary.
Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DesmopressinA synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
CetrorelixA synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy.
VasopressinA peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy.
FelypressinFor use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.
PentagastrinA gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors.
GonadorelinA synthetic GnRH used to test the function of gonadotropes and the pituitary.
NafarelinA gonadotropin releasing hormone agonist used to treat central precocious puberty.
Aminolevulinic acidA porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma.
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
TerlipressinCommonly used to stop bleeding of varices in the food pipe (oesophagus).
VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
NesiritideA recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
G17DTIntended for the treatment of various forms of cancer.
DirucotideFor the treatment of multiple sclerosis (MS).
CR665Investigated for use/treatment in pain (acute or chronic).
Ciliary neurotrophic factorInvestigated for use/treatment in eye disorders/infections, macular degeneration, and retinal disorders (unspecified).
CorticorelinInvestigated for use/treatment in brain cancer and neurologic disorders.
IcatibantA bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE).
AviptadilNot Annotated
Calcitonin gene-related peptideInvestigated for use/treatment in myocardial infarction, heart disease, and asthma.
LabradimilInvestigated for use/treatment in brain cancer and pediatric indications.
PasireotideA somatostatin analog used in the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery is not appropriate.
BuserelinA LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.
SaralasinNot Annotated
GanirelixA GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges.
HistrelinA GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer.
LanreotideA somatostatin analog used for the treatment of unresectable, well- or moderately-differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors and acromegaly.
TriptorelinA GnRH agonist indicated for the palliative treatment of advanced prostate cancer.
DADLEA delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
DPDPEA heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
TesamorelinA growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy.
Corticorelin ovine triflutateA synthetic corticotropin-releasing hormone used for diagnostic purposes in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.
SomatostatinA naturally-occurring peptide hormone used for the symptomatic treatment of acute bleeding from esophageal varices.
PolaprezincPeptic ulcer disease, dyspepsia .
ProtirelinA synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland.
Secretin porcineA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
DeslorelinDeslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones.
BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of...
CarnosineCarnosine has been investigated for the treatment of Gulf War Illness.
SetmelanotideSetmelanotide has been investigated for the treatment of obesity.
BombesinBombesin is under investigation in clinical trial NCT01205321 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Biodistribution, Safety and Tolerability and Diagnostic Performance of BAY86-7548 in Patients With Prostate Cancer and...
Neuropeptide YNeuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus.
Angiotensin IIA peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock.
TAK-448TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
TT-232Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).
BradykininBradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
SelepressinSelepressin has been used in trials studying the treatment of Septic Shock.
PentetreotidePentetreotide has been used in trials studying the diagnostic of cushing syndrome.
Nerve Growth FactorNerve Growth Factor has been used in trials studying the prevention and treatment of Mental Handicap, Alzheimer's Disease, Traumatic Brain Injury, Cerebral Palsy Children, and Delayed Speech Development, among others.
TiplimotideTiplimotide has been used in trials studying the treatment of Multiple Sclerosis.
Zoptarelin doxorubicinZoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others.
SomatoprimSomatoprim is under investigation for the treatment of Acromegaly.
Pancreatic PolypeptidePancreatic Polypeptide has been investigated for the treatment of Diabetes Mellitus, Type 1.
Urocortin-2Urocortin 2 has been investigated for the basic science of Heart Failure and Cardiovascular Disease.
AlsactideNot Annotated
OrnipressinNot Annotated
AngiotensinamideNot Annotated
ElcatoninNot Annotated
Secretin humanA secretin hormone used to stimulate pancreatic or gastric secretions to diagnose exocrine pancreas dysfunction, gastrinoma, and abnormalities in the bile and pancreatic ducts.
LypressinNot Annotated
Indium In-111 pentetreotideIndium In 111 pentetreotide (Octreoscan) has been used in trials studying the diagnostic of SARCOIDOSIS, Solid Tumors, and cushing syndrome.
Sar9, Met (O2)11-Substance PInvestigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection.
Gastric inhibitory polypeptideGastric inhibitory polypeptide is under investigation in clinical trial NCT03081676 (The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea).
Contulakin-GInvestigated for use/treatment in pain (acute or chronic).
Angiotensin 1-7TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
AclerastideAclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
TirzepatideTirzepatide is under investigation in clinical trial NCT03311724 (A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes).
Drugs & Drug Targets
DrugTargetType
LeuprolideGonadotropin-releasing hormone receptortarget
LeuprolideCytochrome P450 3A4enzyme
SermorelinGrowth hormone-releasing hormone receptortarget
GoserelinLutropin-choriogonadotropic hormone receptortarget
GoserelinGonadotropin-releasing hormone receptortarget
Salmon calcitoninCalcitonin receptortarget
DesmopressinVasopressin V1a receptortarget
DesmopressinVasopressin V1b receptortarget
DesmopressinVasopressin V2 receptortarget
DesmopressinProstaglandin G/H synthase 1enzyme
DesmopressinProstaglandin G/H synthase 2enzyme
CetrorelixLutropin-choriogonadotropic hormone receptortarget
CetrorelixGonadotropin-releasing hormone receptortarget
VasopressinVasopressin V1a receptortarget
VasopressinVasopressin V2 receptortarget
VasopressinVasopressin V1b receptortarget
VasopressinCanalicular multispecific organic anion transporter 1transporter
FelypressinVasopressin V1a receptortarget
PentagastrinGastrin/cholecystokinin type B receptortarget
PentagastrinCholinesteraseenzyme
GonadorelinGonadotropin-releasing hormone receptortarget
GonadorelinPutative gonadotropin-releasing hormone II receptortarget
NafarelinGonadotropin-releasing hormone receptortarget
NafarelinPutative gonadotropin-releasing hormone II receptortarget
Aminolevulinic acidDelta-aminolevulinic acid dehydratasetarget
Aminolevulinic acidSolute carrier family 15 member 1transporter
Aminolevulinic acidSolute carrier family 15 member 2transporter
TetracosactideAdrenocorticotropic hormone receptortarget
CorticotropinAdrenocorticotropic hormone receptortarget
CorticotropinCorticoliberintarget
Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CorticotropinCytochrome P450 3A4enzyme
TerlipressinVasopressin V1a receptortarget
TerlipressinVasopressin V2 receptortarget
TerlipressinVasopressin V1b receptortarget
VapreotideNeurokinin 1 receptortarget
VapreotideSomatostatin receptor type 2target
VapreotideSomatostatin receptor type 5target
VapreotideCytochrome P450 3A4enzyme
NesiritideAtrial natriuretic peptide receptor 1target
NesiritideAtrial natriuretic peptide receptor 2target
NesiritideAtrial natriuretic peptide receptor 3target
CR665Kappa-type opioid receptortarget
CorticorelinDopamine beta-hydroxylaseenzyme
IcatibantB2 bradykinin receptortarget
IcatibantAminopeptidase Ntarget
LabradimilB2 bradykinin receptortarget
PasireotideSomatostatin receptor type 1target
PasireotideSomatostatin receptor type 2target
PasireotideSomatostatin receptor type 3target
PasireotideSomatostatin receptor type 5target
PasireotideCytochrome P450 3A4enzyme
BuserelinLutropin-choriogonadotropic hormone receptortarget
BuserelinGonadotropin-releasing hormone receptortarget
BuserelinCytochrome P450 19A1enzyme
GanirelixGonadotropin-releasing hormone receptortarget
HistrelinGonadotropin-releasing hormone receptortarget
LanreotideSomatostatin receptor type 2target
LanreotideSomatostatin receptor type 5target
LanreotideCytochrome P450 3A4enzyme
TriptorelinGonadotropin-releasing hormone receptortarget
DADLESolute carrier organic anion transporter family member 1B1transporter
DPDPESolute carrier organic anion transporter family member 1B3transporter
TesamorelinGrowth hormone-releasing hormone receptortarget
Corticorelin ovine triflutateCorticotropin-releasing factor receptor 1target
SomatostatinSomatostatin receptor type 1target
SomatostatinSomatostatin receptor type 2target
SomatostatinSomatostatin receptor type 3target
SomatostatinSomatostatin receptor type 4target
SomatostatinSomatostatin receptor type 5target
SomatostatinP-glycoprotein 1transporter
SomatostatinCytochrome P450 3A4enzyme
PolaprezincTumor necrosis factortarget
PolaprezincInterleukin-6target
PolaprezincInterleukin-3target
PolaprezincSuperoxide dismutase [Cu-Zn]enzyme
PolaprezincHeme oxygenase 1enzyme
PolaprezincSuperoxide dismutase [Mn], mitochondrialenzyme
PolaprezincGlutathione S-transferase theta-1enzyme
PolaprezincGlutathione peroxidase 1enzyme
PolaprezincPeroxiredoxin-1enzyme
PolaprezincPeroxiredoxin-5, mitochondrialenzyme
PolaprezincVascular endothelial growth factor receptor 1target
PolaprezincBeta-nerve growth factortarget
PolaprezincPlatelet-derived growth factor receptor betatarget
PolaprezincHeat shock protein HSP 90-alphatarget
PolaprezincHeat shock protein HSP 90-betatarget
ProtirelinThyrotropin Releasing Hormone Receptortarget
BremelanotideMelanocyte-stimulating hormone receptortarget
BremelanotideMelanocortin receptor 4target
BremelanotideMelanocortin receptor 3target
BremelanotideMelanocortin receptor 5target
BremelanotideAdrenocorticotropic hormone receptortarget
Angiotensin IIType-1 angiotensin II receptortarget
Secretin humanSecretin receptortarget
LypressinVasopressin V1a receptortarget
LypressinVasopressin V2 receptortarget
LypressinVasopressin V1b receptortarget
LypressinCanalicular multispecific organic anion transporter 1transporter
Sar9, Met (O2)11-Substance PCytochrome P450 19A1enzyme
Sar9, Met (O2)11-Substance PCholinesteraseenzyme
Sar9, Met (O2)11-Substance PProstaglandin G/H synthase 2enzyme
Contulakin-GVoltage-dependent N-type calcium channel subunit alpha-1Btarget