Amino Acids, Cyclic
- Amino Acids, Cyclic
- Accession Number
A class of amino acids characterized by a closed ring structure.
Drug Drug Description Histidine An amino acid commonly found as a component of total parenteral nutrition. Phenylalanine An amino acid commonly found as a component of total parenteral nutrition. Tyrosine An amino acid commonly found as a component in total parenteral nutrition. Tryptophan An amino acid commonly found as a component of total parenteral nutrition. Proline An amino acid commonly found as a component of total parenteral nutrition. Levothyroxine A synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics. Dextrothyroxine A thyroid hormone used to treat hyperlipidemia. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Metyrosine A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma. Tirofiban A platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. Methyldopa An alpha-2 adrenergic agonist used to treat hypertension. Melphalan An alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma. Captopril An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Liotrix May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... Pyrrole-2-Carboxylate Not Available N-(2-Acetamido)Iminodiacetic Acid Not Available Oxitriptan For use as an antidepressant, appetite suppressant, and sleep aid. Pidolic acid There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in... N,O-Didansyl-L-Tyrosine Not Available Diphthamide Not Available N-Acetylproline Not Available L-tyrosinamide Not Available 3-Tyrosine Not Available 4-Iodo-L-phenylalanine Not Available Batimastat Not Available Phenylalanylamide Not Available L-proline betaine Not Available 6-hydroxydopa quinone Not Available Paratoulene phosphate Not Available Phenyldehydroalanine Not Available Cycloleucine Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments. CDP323 Investigated for use/treatment in multiple sclerosis. LX1031 Irritable bowel syndrome (IBS) and other gastrointestinal disorders WX-UK1 Investigated for use/treatment in solid tumors. GW-559090 Investigated for use/treatment in asthma and allergic rhinitis. Etilevodopa Investigated for use/treatment in parkinson's disease. Hydroxyproline Used in France as a combination product for the treatment of small, superficial wounds. Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Technetium Tc-99m mebrofenin A diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests. Technetium Tc-99m disofenin A radiopharmaceutical diagnostic agent used for hepatobiliary scans. Azelnidipine For the treatment of hypertension. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. Hydrogen peroxide A compound used as a disinfectant and sterilizer. N-acetyltyrosine An amino acid used in total parenteral nutrition. Pidotimod For use as immunostimulant therapy for treatment of cell-mediated immunosuppression with respiratory or urinary infections . Lifitegrast A medication used to treat dry eye disease. Raxatrigine Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression. Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Telotristat ethyl A tryptophan hydroxylase inhibitor used to treat carcinoid syndrome. Oxothiazolidinecarboxylic acid Procysteine has been used in trials studying the treatment of HIV Infections. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Indoximod Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others. Macimorelin A medication used to treat adult growth hormone deficiency. Tiropramide Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome). Zofenopril Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor. Melevodopa Not Annotated Oxaceprol Not Annotated Nordazepam An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group. Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. Zofenoprilat Not Available AB192 Investigated for use/treatment in diabetes mellitus type 2. Tiratricol A metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome. 5-fluorotryptophan 5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy. GS-9191 GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts). Fluorodopa (18F) Not Annotated Solriamfetol Solriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744]. 5-Oxoprolinal Not Available p-Benzoyl-L-phenylalanine Not Available Tetraiodothyroacetic acid Not Available 3-nitro-L-tyrosine Not Available Tryptophanamide Not Available 1-Methylhistidine Not Available methyl L-phenylalaninate Not Available
- Drugs & Drug Targets