|DB00132||alpha-Linolenic acid||For nutritional supplementation and for treating dietary shortage or imbalance.|
|DB00159||Icosapent||EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.|
|DB00965||Ethiodized oil||For use as a radio-opaque medium for hysterosalpingography and lymphography, and as an antineoplastic agent when part of the iodine is 131-I. It is also used in follow-up imaging for chemoembolization.|
|DB02955||Ricinoleic Acid||Not Available|
|DB08887||Icosapent ethyl||Icosapent ethyl is used as adjunct therapy to reduce triglyceride (TG) levels in adults with severe (>500 mg/dL) hypertriglyceridemia. |
|DB09422||Soybean oil||Indicated for parenteral nutrition as a source of calories and essential fatty acids when oral or enteral nutrition is not possible, insufficient, or contraindicated. |
|DB09446||Safflower oil||No approved therapeutic indications.|
|DB09539||Omega-3-acid ethyl esters||Omega-3-Acid Ethyl Esters capsules, USP are indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia (HTG)[FDA Label][A176687].|
|DB09543||Methyl salicylate||Ointments or liniments containing methyl salicylate are applied topically as counter irritant for relief of acute pain associated with lumbago,sciatica and rheumatic conditions. Local analgesics for human and veterinary medicine.|
|DB09567||Olive oil||For use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.|
|DB11113||Castor oil||Indicated for over-the-counter use as a laxative for oral use and as a soothing agent for topical use on skin and hair. |
|DB11120||Turpentine||Turpentine has been used experimentally in a bath for the treatment of disseminated sclerosis and sexual dysfunction. It also has been studied for its antibacterial activity and inhibition of osteoclast activity. Turpentine is utilized in experimental models of inflammation to induce a systemic inflammatory immune response in animals.|
|DB11133||Omega-3 fatty acids||Provided as daily supplements. Aa preparation of omega-3-acid ethyl esters is licensed in UK for prevention of recurrent events after myocardial infarction in addition to treatment of hypertriglyceridaemia. |
|DB11172||Sesame oil||Not Available|
|DB11198||Peppermint oil||Indicated for the over-the-counter use for:
-the symptomatic relief of minor spasms of the gastrointestinal tract, flatulence and abdominal pain, especially in patients with irritable bowel syndrome.
-the temporary relief of itching associated with insect bites, eczema, minor burn, sunburn, minor skin irritations, minor cuts, scrapes, atopic dermatitis and other skin disorders.
-the temporary symptomatic relief of mild joint and muscle pain as a local topical analgesic.
-the temporary relief of tension-type headache.|
|DB11218||Tea tree oil||Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.|
|DB11238||Borage oil||Not Available|
|DB11293||Rice bran oil||Not Available|
|DB11321||Cod liver oil||Cod liver oil is predominantly manufactured, marketed, and used by the population at large as a general nutraceutical dietary supplement [A27154, A33159, L2872].
Historically, cod liver oil was often given to children because the vitamin d content in the oil had been shown to prevent or treat vitamin D deficiency and condition of rickets associated with it [A33159]. Over time, this common use in children growing up may have conferred upon cod liver oil its identity as a healthy and useful all-purpose dietary supplement.
However, since cod liver oil is a composite of several other nutritional compounds including the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as well as vitamin A and vitamin D [A33159, L2872, L2871], the presence in varying amounts of all of these compounds at once makes it difficult to recommend or use cod liver oil as an appropriate supplement to confer any one particular health effect or for any one particular nutritional deficiency.
Regardless, because it does contain a combination of a number of important and healthy nutritional compounds, cod liver oil has sometimes been recommended in the literature for conferring the health effects of some of these compounds, such as the potential use of cod liver oil supplements in post-heart attack patients for secondary prophylaxis associated with the use of omega-3 fatty acids [A33165].|
|DB11338||Clove oil||Clove oil is primarily indicated in conditions like colic, flatulence, and toothache [L2849].|
|DB11357||Linseed oil||Not Available|
|DB11358||Evening primrose oil||Evening primrose oil is used as part of over-the-counter dietary supplements.[L1113]
It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical mastalgia. These indications do not have sufficient evidence of their effectiveness. It was used for the treatment of atopic dermatitis in the United Kingdom but it is currently withdrawn due to lack of evidence of effectiveness.[A33131]|
|DB13105||Resolvin E1||Not Available|
|DB13153||Levomenol||Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain molecules|
|DB13961||Fish oil||Under FDA approval, fish oil pharmaceuticals are typically products consisting of a combination of the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and are indicated primarily as an adjunct to diet to reduce triglyceride levels in adult patients with severe (>=500 mg/dL) hypertriglyceridemia [FDA Label, F36].
Under EMA approval, such fish oil pharmaceuticals comprised of virtually the same fish and fish oil derived omega-3-fatty acids EPA and DHA are indicated specifically for (a) adjuvant treatment in secondary prevention after myocardial infarction, in addition to other standard therapy (ie. statins, antiplatelet medicinal products, beta blockers, ACE inhibitors), and (b) as a supplement to diet when dietary measures alone are insufficient to produce an adequate response, particularly with type IV hypertriglyceridemia in monotherapy or type IIb/III in combination with statins, when control of triglycerides is insufficient [L2661]. In addition, prescribing information for EMA approved fish oil pharmaceuticals are also indicated as an adjunct to diet to reduce very high (>=500 mg/dL) triglyceride levels in adult patients, much like similar FDA approved indications [F37, FDA Label].|
|DB13964||Peanut oil||Peanut oil is widely used in food and it is even the component for the adulteration of olive oil.[T41] It is used in over-the-counter ear drops to help lubricate the ear wax.[F124] It was also used as an ingredient in cleansing soaps, in emollient cream preparations or in laxatives.[L2892, F125]
Peanut oil is also used usually to solubilize drugs with poor water solubility as part of the oral formulation.[T224]
When orally administered, peanut oil has as well been researched and used to prevent heart diseases and lower cholesterol levels as well as to aid in weight loss and decrease appetite.[L2897]|
|DB14309||Meadowfoam seed oil||Not Available|
|DB14310||Argan oil||Not Available|
|DB14322||Coconut oil||Not Available|
|DB14329||Sunflower oil||Not Available|
|DB14335||Bergamot oil||Not Available|
|DB14377||Palm oil||Not Available|
|DB14566||Lavender oil||Not Available|
|DB14689||Rosemary oil||Not Available|
|DB03756||Doconexent||Used as a high-docosahexaenoic acid (DHA) oral supplement. |
|DB10917||Juniperus virginiana||Not Available|
|DB11114||Eucalyptus oil||As an active agent, eucalyptus oil has been indicated for relief of the symptoms of catarrhal colds, and/or the relief of the symptoms of minor muscular sprains and cramps [L1857].|