Name
Oils
Accession Number
DBCAT000299
Description

Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)

Drugs
DrugDrug Description
alpha-Linolenic acidA polyunsaturated omega-3 fatty acid found in many supplements.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
Ethiodized oilA contrast agent used in imaging procedures.
Ricinoleic AcidNot Available
Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
Olive oilFor use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.
Castor oilAn ingredient used in a variety of natural health products.
TurpentineA medication used to treat minor aches and pains of muscles and joints.
Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Peppermint oilAn ingredient used in a variety of natural health products and is not an approved medication.
Tea tree oilIndicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.
Borage oilBorage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as...
Rice bran oilRice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It...
Cod liver oilAn ingredient found in a variety of nutritional products.
Clove oilClove oil is primarily indicated in conditions like colic, flatulence, and toothache .
Linseed oilLinseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic...
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
LevomenolLevomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain...
Fish oilA source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement.
Peanut oilA compound used to lubricate ear wax, as an emollient, and used in laxatives.
WormwoodWormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Meadowfoam seed oilMeadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Argan oilArgan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Coconut oilCoconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Sunflower oilSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Bergamot oilBergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Palm oilPalm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Lavender oilNot Annotated
Rosemary oilNot Annotated
DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
Juniperus virginianaAn extract from Juniperus virginiana used in allergy testing.
Eucalyptus oilAn ingredient used in a variety of natural health products.
Drugs & Drug Targets
DrugTargetType
alpha-Linolenic acidFatty acid-binding protein, braincarrier
alpha-Linolenic acidFatty acid desaturase 1target
alpha-Linolenic acidFatty acid desaturase 2target
alpha-Linolenic acidSodium/calcium exchanger 1target
alpha-Linolenic acidTransient receptor potential cation channel subfamily V member 1target
alpha-Linolenic acidPeroxisome proliferator-activated receptor alphatarget
alpha-Linolenic acidBile acid receptortarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor deltatarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor gammatarget
alpha-Linolenic acidRetinoic acid receptor RXR-alphatarget
alpha-Linolenic acidElongation of very long chain fatty acids protein 2target
alpha-Linolenic acidElongation of very long chain fatty acids protein 5target
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentFatty acid-binding protein, braincarrier
IcosapentFatty acid desaturase 1target
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentSerum albumincarrier
Ricinoleic AcidCannabinoid receptor 1target
Ricinoleic AcidCannabinoid receptor 2target
Ricinoleic AcidTransient receptor potential cation channel subfamily V member 1target
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
Castor oilProstaglandin E2 receptor EP3 subtypetarget
Castor oilProstaglandin E2 receptor EP4 subtypetarget
TurpentineMitogen-activated protein kinase 1target
Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
Omega-3 fatty acidsArachidonate 5-lipoxygenaseenzyme
Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
Omega-3 fatty acidsSterol regulatory element-binding protein 1target
Peppermint oilCytochrome P450 1A2enzyme
Peppermint oilCytochrome P450 3A4enzyme
Clove oilVascular cell adhesion protein 1target
Clove oilC-X-C motif chemokine 10target
Clove oilCollagen alpha-1(I) chaintarget
Clove oilGranulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
LevomenolSolute carrier organic anion transporter family member 1B1transporter
LevomenolSolute carrier organic anion transporter family member 1B3transporter
Fish oilDiacylglycerol O-acyltransferase 2target
Fish oilProstaglandin G/H synthase 2target
Fish oilFree fatty acid receptor 4target
Fish oilVoltage gated L-type calcium channeltarget
Fish oilSodium channel proteintarget
Fish oilFree radicalstarget
Fish oilNuclear factor NF-kappa-Btarget
Fish oilSterol regulatory element-binding protein 1target
Fish oilPeroxisome proliferator-activated receptor alphatarget
Fish oilPeroxisome proliferator-activated receptor gammatarget
Fish oilPeroxisome proliferator-activated receptor deltatarget
Fish oilCytochrome P450 3A4enzyme
DoconexentCytochrome P450 2C9enzyme
DoconexentPeroxisome proliferator-activated receptor alphatarget
DoconexentPeroxisome proliferator-activated receptor gammatarget
DoconexentSterol regulatory element-binding protein 1target
DoconexentRetinoic acid receptor RXR-alphatarget
DoconexentRetinoic acid receptor RXR-betatarget
DoconexentRetinoic acid receptor RXR-gammatarget