Phosphorus Acids

Inorganic acids that contain phosphorus as an integral part of the molecule.
DrugDrug NameDrug Indication
DB00492FosinoprilFor treating mild to moderate hypertension, use as an adjunct in treating congestive heart failure, and may be used to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.
DB00531CyclophosphamideCyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients.
DB01181IfosfamideUsed as a component of various chemotherapeutic regimens as third-line therapy for recurrent or refractory germ cell testicular cancer. Also used as a component of various chemotherapeutic regimens for the treatment of cervical cancer, as well as in conjunction with surgery and/or radiation therapy in the treatment of various soft tissue sarcomas. Other indications include treatment of osteosarcoma, bladder cancer, ovarian cancer. small cell lung cancer, and non-Hodgkin's lymphoma.
DB02423ThiopyrophosphateNot Available
DB02552Geranyl DiphosphateNot Available
DB02845Methylphosphinic AcidNot Available
DB03822Ethyl Dihydrogen PhosphateNot Available
DB04160Pyrophosphoric acidNot Available
DB04572ThiotepaThioTEPA is used a as conditioning treatment prior to allogeneic or autologous haematopoietic progenitor cell transplantation (HPCT) in haematological diseases in adult and paediatric patients. Also, when high dose chemotherapy with HPCT support it is appropriate for the treatment of solid tumours in adult and paediatric patients.
DB05143OXI-4503Investigated for use/treatment in cancer/tumors (unspecified).
DB05404AZD 3355Investigated for use/treatment in gastroesophageal reflux disease (GERD).
DB05668PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
DB06091EvofosfamideInvestigated for use/treatment in solid tumors.
DB06166FosdevirineInvestigated for use/treatment in HIV infection and acquired immune deficiency syndrome (AIDS) and aids-related infections.
DB06177GlufosfamideInvestigated for use/treatment in pancreatic cancer, solid tumors, breast cancer, colorectal cancer, brain cancer, lung cancer, ovarian cancer, and sarcoma.
DB09147Ferric pyrophosphateFerric pyrophosphate is intended to be indicated for the treatment of iron loss or iron deficiency as a formulation with a milder gastrointestinal effect.[L1423, L1433] Iron deficiency appears when the dietary intake does not meet the body's requirement or when there is chronic external blood loss. During acute blood loss, body iron stores are sufficient for accelerated erythropoiesis and restoration of iron homeostasis. But when the altered homeostasis remains for weeks to months then some supplement is needed. Some causes of iron deficiency include ectoparasitism, endoparasitism, hematuria, epistaxis, hemorrhagic skin, coagulopathy, thrombocytopenia, thrombocytopathia and gastrointestinal hemorrhage.[A31984]
DB09165Technetium Tc-99m pyrophosphateFor use as a skeletal imaging agent used to demonstrate areas of altered osteogenesis, and a cardiac imaging agent used as an adjunct in the diagnosis of acute myocardial infarction [FDA Label]. May also be used to image gated blood pools and detect gastrointetinal bleeding.
DB09394Phosphoric acidPhosphoric acid is used in dentistry and orthodontics as an etching solution, to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed.
DB09413Monopotassium phosphateUsed in buffers (determination of pH, pharmaceutical production, urinary acidifier, paper processing, baking powder, and food), nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications; Used as a nutritional supplement in foods, a nonlinear optical material for laser use, and in wastewater treatment;
DB09414Dipotassium phosphateDipotassium phosphate is used in imitation dairy creamers, dry powder beverages, mineral supplements, and starter cultures as an additive. It is used in non-dairy creamers to prevent coagulation. Dipotassium phosphate is also used to make buffer solutions and it is used in the production of trypticase soy agar which is used to make agar plates for culturing bacteria.
DB09423Technetium Tc-99m polyphosphateNot Available
DB09449Sodium phosphate, monobasicUsed to treat constipation or to clean the bowel before a colonoscopy [FDA Label].
DB09484Sodium fluorophosphateSodium monofluorophosphate is indicated for the treatment of cavities
DB11348Calcium PhosphateFor use as an over the counter calcium and phosphate supplement, antacid, or a source of calcium and phosphate in toothpaste [FDA Label] [L851].
DB11493Sodium tripolyphosphateNot Available
DB11920LesogaberanNot Available
DB12083MafosfamideNot Available
DB12727PerfosfamideNot Available
DB12876GS-9256Not Available
DB12902TrofosfamideNot Available
DB13862Magnesium phosphateNot Available
DB14207FosinoprilatNot Available
DB14481Calcium phosphate dihydrateFor use as an over the counter calcium and phosphate supplement, antacid, or a source of calcium and phosphate in toothpaste [FDA Label] [L851].
DB14502Sodium phosphate, dibasicUsed to treat constipation or to clean the bowel before a colonoscopy [FDA Label].
DB14517Aluminium phosphateNot Available
DB14523Phosphate ionNot Available
DB14622Sodium phosphate tribasic dodecahydrateNot Available
DB02348Monofluorophosphate ionNot Available
DB03896Triphosphoric acidNot Available
DB00102BecaplerminFor topical treatment of skin ulcers (from diabetes)
DrugDrug NameTargetType
DB00492FosinoprilAngiotensin-converting enzymetarget
DB00492FosinoprilSolute carrier family 15 member 1transporter
DB00492FosinoprilSolute carrier family 15 member 2transporter
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB01181IfosfamideCytochrome P450 2B6enzyme
DB01181IfosfamideDNAtarget
DB01181IfosfamideCytochrome P450 3A4enzyme
DB01181IfosfamideCytochrome P450 3A5enzyme
DB01181IfosfamideCytochrome P450 2C9enzyme
DB01181IfosfamideCytochrome P450 2C8enzyme
DB01181IfosfamideCytochrome P450 2A6enzyme
DB01181IfosfamideCytochrome P450 2C19enzyme
DB01181IfosfamideCytochrome P450 2C18enzyme
DB01181IfosfamideProstaglandin G/H synthase 1enzyme
DB01181IfosfamideNuclear receptor subfamily 1 group I member 2target
DB02552Geranyl Diphosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
DB02552Geranyl DiphosphateBifunctional enzyme IspD/IspFtarget
DB02552Geranyl Diphosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
DB02552Geranyl DiphosphateFarnesyl pyrophosphate synthasetarget
DB02552Geranyl DiphosphatePrenyltransferasetarget
DB02552Geranyl DiphosphateGeranylgeranyl pyrophosphate synthasetarget
DB02552Geranyl Diphosphate(2Z,6E)-farnesyl diphosphate synthasetarget
DB02552Geranyl DiphosphateDecaprenyl diphosphate synthasetarget
DB02845Methylphosphinic AcidEsterasetarget
DB02845Methylphosphinic AcidCholinesterasetarget
DB02845Methylphosphinic AcidAcetylcholinesterasetarget
DB02845Methylphosphinic AcidCholinesteraseenzyme
DB03822Ethyl Dihydrogen PhosphateParathion hydrolasetarget
DB03822Ethyl Dihydrogen PhosphateCholinesterasetarget
DB03822Ethyl Dihydrogen PhosphateCholinesteraseenzyme
DB04160Pyrophosphoric acidNH(3)-dependent NAD(+) synthetasetarget
DB04160Pyrophosphoric acidThymidylate kinasetarget
DB04160Pyrophosphoric acidFerrichrome-iron receptortarget
DB04160Pyrophosphoric acidFarnesyl diphosphate synthasetarget
DB04160Pyrophosphoric acidIsopentenyl-diphosphate Delta-isomerasetarget
DB04160Pyrophosphoric acidAdenylosuccinate synthetasetarget
DB04572ThiotepaCytochrome P450 2B6enzyme
DB04572ThiotepaCytochrome P450 3A4enzyme
DB04572ThiotepaDNAtarget
DB04572ThiotepaCholinesteraseenzyme
DB05404AZD 3355Cellular tumor antigen p53target
DB05668PalifosfamideDNA (cytosine-5)-methyltransferase 1target
DB09147Ferric pyrophosphateFerritin light chaintarget
DB09147Ferric pyrophosphateHemoglobin subunit alphatarget
DB09147Ferric pyrophosphateHemoglobin subunit betatarget
DB09165Technetium Tc-99m pyrophosphateHydroxyapatitetarget
DB09165Technetium Tc-99m pyrophosphateAmorphous calcium phosphatetarget
DB09413Monopotassium phosphateIntestinal-type alkaline phosphataseenzyme
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transporter 1transporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transporter 2transporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Atransporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Btransporter
DB09449Sodium phosphate, monobasicSodium-dependent phosphate transport protein 2Ctransporter
DB11348Calcium PhosphateSodium-dependent phosphate transporter 1transporter
DB11348Calcium PhosphateSodium-dependent phosphate transporter 2transporter
DB11348Calcium PhosphateSodium-dependent phosphate transport protein 2Atransporter
DB11348Calcium PhosphateSodium-dependent phosphate transport protein 2Btransporter
DB11348Calcium PhosphateSodium-dependent phosphate transport protein 2Ctransporter
DB11348Calcium PhosphateTransient receptor potential cation channel subfamily V member 6transporter
DB11348Calcium PhosphateCalbindincarrier
DB11348Calcium PhosphateProtein S100-Gcarrier
DB11348Calcium PhosphateSodium/calcium exchanger 1transporter
DB11348Calcium PhosphateTransient receptor potential cation channel subfamily V member 5transporter
DB11348Calcium PhosphateExtracellular calcium-sensing receptortarget
DB11348Calcium PhosphateCalreticulintarget
DB11348Calcium PhosphateCalcium and integrin-binding protein 1target
DB11348Calcium PhosphateProgrammed cell death protein 6target
DB11348Calcium PhosphateSorcintarget
DB11348Calcium PhosphateCalcineurin B homologous protein 1target
DB11348Calcium PhosphateSPARCtarget
DB11348Calcium PhosphateCalnexintarget
DB11348Calcium PhosphateFibrillin-2target
DB11348Calcium PhosphateProtein S100-Btarget
DB11348Calcium PhosphateCalsequestrin-2target
DB11348Calcium PhosphateRegucalcintarget
DB11348Calcium PhosphatePeflintarget
DB11348Calcium PhosphateProtein S100-A6target
DB11348Calcium PhosphateTranslationally-controlled tumor proteintarget
DB11348Calcium PhosphateCalcium and integrin-binding family member 2target
DB11348Calcium PhosphateProtein S100-A13target
DB11348Calcium PhosphateCalsequestrin-1target
DB11348Calcium PhosphateNucleobindin-1target
DB11348Calcium PhosphateNucleobindin-2target
DB11348Calcium PhosphateCalmodulintarget
DB11348Calcium PhosphateFibrillin-3target
DB11348Calcium PhosphateGrancalcintarget
DB11348Calcium PhosphateCalcium-dependent secretion activator 1target
DB11348Calcium PhosphateSerum albumincarrier
DB11348Calcium PhosphateCalmodulin-2target
DB11348Calcium PhosphateCalmodulin-3target
DB11348Calcium PhosphateProtein S100-A16target
DB11348Calcium PhosphateCalretinintarget
DB11348Calcium PhosphateCalcyphosintarget
DB11348Calcium PhosphateCalcium-dependent secretion activator 2target
DB11348Calcium PhosphateCalreticulin-3target
DB11348Calcium PhosphateRyanodine receptor 1transporter
DB11348Calcium PhosphateRyanodine receptor 2transporter
DB11348Calcium PhosphatePolycystic kidney disease 2-like 1 proteintransporter
DB11348Calcium PhosphateNeurexin-1target
DB11348Calcium PhosphateNeuronal calcium sensor 1target
DB11348Calcium PhosphateRyanodine receptor 3transporter
DB11348Calcium PhosphatePolycystic kidney disease protein 1-like 3transporter
DB11348Calcium PhosphateCation channel sperm-associated protein 1transporter
DB11348Calcium PhosphateVoltage-dependent L-type calcium channeltransporter
DB11348Calcium PhosphateVoltage-dependent P/Q-type calcium channeltransporter
DB11348Calcium PhosphateVoltage-dependent T-type calcium channeltransporter
DB11348Calcium PhosphateVoltage-dependent R-type calcium channeltransporter
DB14481Calcium phosphate dihydrateCalbindincarrier
DB14481Calcium phosphate dihydrateProtein S100-Gcarrier
DB14481Calcium phosphate dihydrateSerum albumincarrier
DB14481Calcium phosphate dihydrateExtracellular calcium-sensing receptortarget
DB14481Calcium phosphate dihydrateCalreticulintarget
DB14481Calcium phosphate dihydrateCalcium and integrin-binding protein 1target
DB14481Calcium phosphate dihydrateProgrammed cell death protein 6target
DB14481Calcium phosphate dihydrateSorcintarget
DB14481Calcium phosphate dihydrateCalcineurin B homologous protein 1target
DB14481Calcium phosphate dihydrateSPARCtarget
DB14481Calcium phosphate dihydrateCalnexintarget
DB14481Calcium phosphate dihydrateFibrillin-2target
DB14481Calcium phosphate dihydrateProtein S100-Btarget
DB14481Calcium phosphate dihydrateCalsequestrin-2target
DB14481Calcium phosphate dihydrateRegucalcintarget
DB14481Calcium phosphate dihydratePeflintarget
DB14481Calcium phosphate dihydrateProtein S100-A6target
DB14481Calcium phosphate dihydrateTranslationally-controlled tumor proteintarget
DB14481Calcium phosphate dihydrateCalcium and integrin-binding family member 2target
DB14481Calcium phosphate dihydrateProtein S100-A13target
DB14481Calcium phosphate dihydrateCalsequestrin-1target
DB14481Calcium phosphate dihydrateNucleobindin-1target
DB14481Calcium phosphate dihydrateNucleobindin-2target
DB14481Calcium phosphate dihydrateCalmodulintarget
DB14481Calcium phosphate dihydrateFibrillin-3target
DB14481Calcium phosphate dihydrateGrancalcintarget
DB14481Calcium phosphate dihydrateCalcium-dependent secretion activator 1target
DB14481Calcium phosphate dihydrateCalmodulin-2target
DB14481Calcium phosphate dihydrateCalmodulin-3target
DB14481Calcium phosphate dihydrateProtein S100-A16target
DB14481Calcium phosphate dihydrateCalretinintarget
DB14481Calcium phosphate dihydrateCalcyphosintarget
DB14481Calcium phosphate dihydrateCalcium-dependent secretion activator 2target
DB14481Calcium phosphate dihydrateCalreticulin-3target
DB14481Calcium phosphate dihydrateNeurexin-1target
DB14481Calcium phosphate dihydrateNeuronal calcium sensor 1target
DB14481Calcium phosphate dihydrateSodium-dependent phosphate transporter 1transporter
DB14481Calcium phosphate dihydrateSodium-dependent phosphate transporter 2transporter
DB14481Calcium phosphate dihydrateSodium-dependent phosphate transport protein 2Atransporter
DB14481Calcium phosphate dihydrateSodium-dependent phosphate transport protein 2Btransporter
DB14481Calcium phosphate dihydrateSodium-dependent phosphate transport protein 2Ctransporter
DB14481Calcium phosphate dihydrateTransient receptor potential cation channel subfamily V member 6transporter
DB14481Calcium phosphate dihydrateSodium/calcium exchanger 1transporter
DB14481Calcium phosphate dihydrateTransient receptor potential cation channel subfamily V member 5transporter
DB14481Calcium phosphate dihydrateRyanodine receptor 1transporter
DB14481Calcium phosphate dihydrateRyanodine receptor 2transporter
DB14481Calcium phosphate dihydratePolycystic kidney disease 2-like 1 proteintransporter
DB14481Calcium phosphate dihydrateRyanodine receptor 3transporter
DB14481Calcium phosphate dihydratePolycystic kidney disease protein 1-like 3transporter
DB14481Calcium phosphate dihydrateCation channel sperm-associated protein 1transporter
DB14481Calcium phosphate dihydrateVoltage-dependent L-type calcium channeltransporter
DB14481Calcium phosphate dihydrateVoltage-dependent P/Q-type calcium channeltransporter
DB14481Calcium phosphate dihydrateVoltage-dependent T-type calcium channeltransporter
DB14481Calcium phosphate dihydrateVoltage-dependent R-type calcium channeltransporter
DB14502Sodium phosphate, dibasicSodium-dependent phosphate transporter 1transporter
DB14502Sodium phosphate, dibasicSodium-dependent phosphate transporter 2transporter
DB14502Sodium phosphate, dibasicSodium-dependent phosphate transport protein 2Atransporter
DB14502Sodium phosphate, dibasicSodium-dependent phosphate transport protein 2Btransporter
DB14502Sodium phosphate, dibasicSodium-dependent phosphate transport protein 2Ctransporter
DB14517Aluminium phosphateSerotransferrintarget
DB14517Aluminium phosphateSodium/potassium-transporting ATPase subunit alpha-1target
DB14517Aluminium phosphateSerum albumincarrier
DB14517Aluminium phosphateKallikrein-1target
DB14517Aluminium phosphateAmyloid beta A4 proteintarget
DB02348Monofluorophosphate ionGlycogen phosphorylase, muscle formtarget
DB03896Triphosphoric acidPoly(A) polymerase alphatarget
DB00102BecaplerminPlatelet-derived growth factor receptor betatarget
DB00102BecaplerminAlpha-2-macroglobulintarget
DB00102BecaplerminPlatelet-derived growth factor receptor alphatarget