Agents to Treat Airway Disease

Name
Agents to Treat Airway Disease
Accession Number
DBCAT002866
Description
Not Available
Drugs
DrugDrug Description
AclidiniumAn inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD).
SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
CiclesonideA glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
LevosalbutamolA beta-2 adrenergic receptor agonist used to treat COPD and asthma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
OmalizumabA monoclonal anti-immunoglobulin E antibody used in the treatment of severe asthma and chronic idiopathic urticaria.
PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
PranlukastUsed as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists.
RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
TulobuterolTulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
UmeclidiniumA long-acting muscarinic antagonist used as a long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD).
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
Drugs & Drug Targets
DrugTargetType
AclidiniumMuscarinic acetylcholine receptor M1target
AclidiniumMuscarinic acetylcholine receptor M2target
AclidiniumMuscarinic acetylcholine receptor M3target
AclidiniumMuscarinic acetylcholine receptor M4target
AclidiniumMuscarinic acetylcholine receptor M5target
AclidiniumCholinesteraseenzyme
SalbutamolBeta-2 adrenergic receptortarget
SalbutamolBeta-1 adrenergic receptortarget
SalbutamolCytochrome P450 3A4enzyme
SalbutamolBeta-3 adrenergic receptortarget
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
BambuterolBeta-2 adrenergic receptortarget
BambuterolCholinesteraseenzyme
Beclomethasone dipropionateCorticosteroid-binding globulincarrier
Beclomethasone dipropionateGlucocorticoid receptortarget
Beclomethasone dipropionateCytochrome P450 3A5enzyme
Beclomethasone dipropionateCytochrome P450 3A4enzyme
Beclomethasone dipropionateP-glycoprotein 1transporter
Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
CiclesonideCorticosteroid-binding globulincarrier
CiclesonideCytochrome P450 3A4enzyme
CiclesonideCytochrome P450 2D6enzyme
CiclesonideGlucocorticoid receptortarget
CiclesonideLiver carboxylesterase 1enzyme
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideGlucocorticoid receptortarget
FlunisolideCytochrome P450 3A4enzyme
Fluticasone furoateCytochrome P450 3A4enzyme
Fluticasone furoateGlucocorticoid receptortarget
Fluticasone furoateP-glycoprotein 1transporter
Fluticasone furoateCytochrome P450 2C8enzyme
Fluticasone furoateSolute carrier organic anion transporter family member 1B1transporter
Fluticasone furoateCorticosteroid-binding globulincarrier
Fluticasone furoateP-glycoprotein 1carrier
Fluticasone furoateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone furoateCytochrome P450 3A5enzyme
Fluticasone furoateCytochrome P450 3A7enzyme
Fluticasone furoateProgesterone receptortarget
Fluticasone furoateMineralocorticoid receptortarget
Fluticasone propionateCorticosteroid-binding globulincarrier
Fluticasone propionateCytosolic phospholipase A2target
Fluticasone propionateGlucocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A4enzyme
Fluticasone propionateProgesterone receptortarget
Fluticasone propionateMineralocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A5enzyme
Fluticasone propionateCytochrome P450 3A7enzyme
Fluticasone propionateCytochrome P450 2C8enzyme
Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone propionateP-glycoprotein 1transporter
Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
IndacaterolBeta-2 adrenergic receptortarget
IndacaterolCytochrome P450 3A4enzyme
IndacaterolUDP-glucuronosyltransferase 1-1enzyme
IndacaterolP-glycoprotein 1transporter
IpratropiumMuscarinic acetylcholine receptor M1target
IpratropiumMuscarinic acetylcholine receptor M2target
IpratropiumMuscarinic acetylcholine receptor M3target
IpratropiumSolute carrier family 22 member 5transporter
IpratropiumSolute carrier family 22 member 4transporter
IpratropiumSerum albumincarrier
Ipratropiumalpha1-acid glycoproteincarrier
LevosalbutamolBeta-2 adrenergic receptortarget
LevosalbutamolCytochrome P450 3A4enzyme
LevosalbutamolCytochrome P450 2D6enzyme
LevosalbutamolSolute carrier organic anion transporter family member 1B1transporter
LevosalbutamolSolute carrier organic anion transporter family member 1B3transporter
OrciprenalineBeta-2 adrenergic receptortarget
MontelukastCysteinyl leukotriene receptor 1target
MontelukastArachidonate 5-lipoxygenasetarget
MontelukastCytochrome P450 3A4enzyme
MontelukastCytochrome P450 2C9enzyme
MontelukastCytochrome P450 2C8enzyme
MontelukastSolute carrier organic anion transporter family member 2B1transporter
MontelukastProstaglandin G/H synthase 1enzyme
MontelukastCytochrome P450 2A6enzyme
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
OmalizumabHigh affinity immunoglobulin epsilon receptor subunit alphatarget
OmalizumabHigh affinity immunoglobulin epsilon receptor subunit betatarget
PirbuterolBeta-2 adrenergic receptortarget
PirbuterolBeta-1 adrenergic receptortarget
PranlukastTumor necrosis factortarget
PranlukastInterleukin-5target
PranlukastEosinophil cationic proteintarget
PranlukastNuclear factor NF-kappa-B p105 subunittarget
PranlukastMucin-2target
PranlukastCysteinyl leukotriene receptor 1target
PranlukastCytochrome P450 3A4enzyme
PranlukastCanalicular multispecific organic anion transporter 1transporter
PranlukastCytochrome P450 2C9enzyme
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
RoflumilastCytochrome P450 3A4enzyme
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
TerbutalineBeta-2 adrenergic receptortarget
TerbutalineCholinesteraseenzyme
TerbutalineBeta-3 adrenergic receptortarget
TerbutalineBeta-1 adrenergic receptortarget
TiotropiumMuscarinic acetylcholine receptor M3target
TiotropiumCytochrome P450 2D6enzyme
TiotropiumCytochrome P450 3A4enzyme
TiotropiumMuscarinic acetylcholine receptor M1target
TiotropiumMuscarinic acetylcholine receptor M2target
TiotropiumSolute carrier family 22 member 5transporter
TiotropiumSolute carrier family 22 member 4transporter
TiotropiumMuscarinic acetylcholine receptor M4target
TiotropiumMuscarinic acetylcholine receptor M5target
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
TulobuterolBeta-2 adrenergic receptortarget
UmeclidiniumMuscarinic acetylcholine receptor M1target
UmeclidiniumMuscarinic acetylcholine receptor M2target
UmeclidiniumMuscarinic acetylcholine receptor M3target
UmeclidiniumMuscarinic acetylcholine receptor M4target
UmeclidiniumMuscarinic acetylcholine receptor M5target
UmeclidiniumCytochrome P450 2D6enzyme
UmeclidiniumP-glycoprotein 1transporter
VilanterolCytochrome P450 3A4enzyme
VilanterolBeta-2 adrenergic receptortarget
ZafirlukastCysteinyl leukotriene receptor 1target
ZafirlukastCytochrome P450 2C9enzyme
ZafirlukastCytochrome P450 2C8enzyme
ZafirlukastProstaglandin G/H synthase 1enzyme
ZafirlukastCytochrome P450 3A4enzyme
ZafirlukastCytochrome P450 1A2enzyme
ZafirlukastCytochrome P450 2C19enzyme
ZafirlukastCytochrome P450 2E1enzyme
ZafirlukastATP-binding cassette sub-family G member 2transporter
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
ClenbuterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-nerve growth factortarget
ClenbuterolTumor necrosis factortarget
ClenbuterolBeta-1 adrenergic receptortarget
ClenbuterolBeta-3 adrenergic receptortarget
ClenbuterolCytochrome P450 1A1enzyme
ProtokylolBeta-2 adrenergic receptortarget