Showing BioInteractions for Exisulind (DB06246)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Exisulind is a Glutathione S-transferase P inhibitor
1Glutathione S-transferase P inhibitorsalpha-Tocopherol succinate, Clomipramine, Curcumin, D-alpha-Tocopherol acetate, Etacrynic acid, Vitamin E
2Glutathione S-transferase P substratesAcetaminophen, Busulfan, Carboplatin, Chlorambucil, Cisplatin, Etoposide, Oxaliplatin
Interacting GroupInteracting Drugs
Exisulind is a Aldose reductase inhibitor
1Aldose reductase inhibitorsCitric acid, Fidarestat, Sorbinil, Sulindac, Tolrestat
2Aldose reductase substratesBrexanolone, Fenofibrate
Interacting GroupInteracting Drugs
Exisulind is a Aldo-keto reductase family 1 member B10 inhibitor
1Aldo-keto reductase family 1 member B10 inhibitorsFidarestat, Sulindac