Benzoin resin

Identification

Name
Benzoin resin
Accession Number
DB11222
Type
Biotech
Groups
Approved
Description

Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus Styrax. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the Styrax tree. Benzoin resin differs from the chemical compound benzoin, which is derived from benzoin resin; however, the resin does not contain this compound (see Benzoin). While benzoin resin is used as a common ingredient in incense-making and perfumery, it is also used clinically as a mild antiseptic agent in over-the-counter products to clean sores, cuts, wounds, and skin abrasions as tincture of benzoin, or benzoin in a solution of alcohol. Tincture of benzoin solution is a topical adhesive agent used to provide tackiness and enhance the adhesive property of tape.

Synonyms
  • Benzoin absolute
  • Benzoin resin, unspecified
  • Benzoin tincture, compound
  • Gum benzoin
  • Gum benzoin tincture
  • Gum sumatra
External IDs
FEMA No. 2133
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Benz ProtectLiquid100 mg/1mLTopicalGeritrex Llc2015-07-31Not applicableUs
Benzoin Compound TinctureLiquid100 mg/1mLTopicalGeritrex Llc2015-07-31Not applicableUs
Benzoin Compound TinctureLiquid1000 mg/1mLTopicalHumco Holding Group, Inc.2008-01-01Not applicableUs
Benzoin Compound Tincture Professional PackLiquid1000 mg/1mLTopicalHumco Holding Group, Inc.1998-03-252020-09-30Us
Benzoin TinctureLiquid1000 mg/1mLTopicalHumco Holding Group, Inc.2008-01-01Not applicableUs
Benzoin TinctureLiquid1000 mg/1mLTopicalHumco Holding Group, Inc.2008-01-01Not applicableUs
Compound BenzoinTincture100 mg/1mLTopicalPaddock Laboratories, LLC2014-04-022018-11-09Us
Compound Benzoin TinctureLiquid10 g/100mLTopicalMedical Chemical Corporation1954-06-15Not applicableUs
Sunmark Benzoin Compound TinctureLiquid1000 mg/1mLTopicalStrategic Sourcing Services LLC2008-01-01Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Blistex Kank-ABenzoin resin (0.5 g/100mL) + Benzocaine (20 g/100mL)LiquidBuccalBlistex Inc.2011-12-01Not applicableUs
Tuffner LiquidBenzoin resin (11.25 gal/216L) + Rosin (3.632 kg/216L)TinctureTopicalMueller Sports Medicine, Inc.1970-12-312003-08-01Canada
Categories
UNII
GK21SBA74R
CAS number
9000-05-9

Pharmacology

Indication

Indicated for mild antisepsis of skin, cuts, and abrasions.

Pharmacodynamics

Benzoin resin exhibits antiseptic properties.

Mechanism of action

The full mechanism of action is not yet fully established. Benzoic acid present in tincture of benzoin as well as the strong alcoholic content of the common pharmaceutical preparation are thought to play antiseptic and dehydrating effects on the oedematous tissue 1. Benzoin resin is thought to form a fine coating under the adhesive tapes and over skin, abrasions, wounds, and oral lesions when used as a topical adhesive agent. Antiseptic preparation maintains skin integrity and protects the skin from adhesive ingredients and body fluids.

Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption

No pharmacokinetic data available.

Volume of distribution

No pharmacokinetic data available.

Protein binding

No pharmacokinetic data available.

Metabolism

No pharmacokinetic data available.

Route of elimination

No pharmacokinetic data available.

Half life

No pharmacokinetic data available.

Clearance

No pharmacokinetic data available.

Toxicity

No toxicokinetic data available.

Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
  1. PERLMAN HH: Compound benzoin tincture in treatment of vesiculobullous lesions of mucous membranes. Arch Derm Syphilol. 1950 Jan;61(1):119-21. [PubMed:15398751]
External Links
PubChem Substance
347911157
RxNav
1406
Wikipedia
Benzoin_(resin)
AHFS Codes
  • 84:04.92 — Miscellaneous Local Anti-infectives
MSDS
Download (67.2 KB)

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LiquidTopical100 mg/1mL
LiquidTopical1000 mg/1mL
LiquidBuccal
TinctureTopical100 mg/1mL
LiquidTopical10 g/100mL
TinctureTopical
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)60MSDS
water solubilityInsolubleMSDS

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on July 11, 2020 00:05

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