Miscellaneous Local Anti-infectives

Name
Miscellaneous Local Anti-infectives
Accession Number
DBCAT003645
Description
Not Available
Drugs
DrugDrug Description
DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
ChlorhexidineAn antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
CetrimoniumA compound that can be used as a topical antiseptic.
Isopropyl alcoholAn antiseptic and disinfectant used in a variety of clinical and domestic settings.
Lactic acidAn emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties.
Silver sulfadiazineA topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns.
IodineAn ingredient of nutritional supplements that is also used for disinfection.
Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
PyrithioneAn antimicrobial agent used for the treatment of dandruff and seborrheic dermatitis.
TriclosanAn antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew.
BenzalkoniumAn antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
ChloroxylenolAn antimicrobial used to treat cuts, bites, stings, abrasions, and used as an antiseptic hand cleaner.
HypochloriteAn antimicrobial used to treat and prevent infections of the skin and tissue.
BenzethoniumA medication used as to clean hands and clean minor cuts and scrapes.
TriclocarbanAn antibacterial agent used in liquid soaps and body washes.
Tea tree oilIndicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications.
Benzoin resinA compound used to protect small wounds or canker sores.
DomiphenAnti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.
IodoformNo approved therapeutic indications.
Drugs & Drug Targets
DrugTargetType
DapsoneInactive dihydropteroate synthase 2target
DapsoneDihydropteroate synthase 1target
DapsoneCytochrome P450 2C9enzyme
DapsoneCytochrome P450 2E1enzyme
DapsoneCytochrome P450 3A4enzyme
DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DapsoneProstaglandin G/H synthase 1enzyme
DapsoneProstaglandin G/H synthase 2enzyme
DapsoneCytochrome P450 2C8enzyme
DapsoneCytochrome P450 2C19enzyme
DapsoneArylamine N-acetyltransferase 2enzyme
DapsoneCytochrome P450 3A5enzyme
DapsoneCytochrome P450 3A7enzyme
DapsoneMyeloperoxidaseenzyme
DapsoneCytochrome P450 2C18enzyme
ChlorhexidineBacterial outer membranetarget
ChlorhexidineSerum albumincarrier
EthanolGamma-aminobutyric acid receptor subunit alpha-1target
EthanolGlutamate receptor ionotropic, NMDA 3Atarget
EthanolGlycine receptor subunit alpha-1target
EthanolGlycine receptor subunit alpha-2target
EthanolCytochrome P450 2E1enzyme
EthanolCytochrome P450 1A1enzyme
EthanolCytochrome P450 1A2enzyme
EthanolCytochrome P450 2B6enzyme
EthanolCytochrome P450 2C19enzyme
EthanolCytochrome P450 2C9enzyme
EthanolCytochrome P450 3A4enzyme
EthanolCytochrome P450 4A11enzyme
EthanolAlcohol dehydrogenase 1Aenzyme
EthanolAlcohol dehydrogenase 1Benzyme
EthanolAlcohol dehydrogenase 1Cenzyme
EthanolAlcohol dehydrogenase class-3enzyme
EthanolVoltage-dependent L-type calcium channel subunit beta-1target
Ethanol5-hydroxytryptamine receptor 3Atarget
EthanolAlcohol dehydrogenase 4enzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-2target
EthanolNeuronal acetylcholine receptor subunit alpha-10target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EthanolGamma-aminobutyric acid receptor subunit alpha-5target
EthanolGamma-aminobutyric acid receptor subunit alpha-4target
EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-3target
EthanolGlutamate receptor 1target
EthanolVoltage-dependent calcium channel gamma-1 subunittarget
EthanolNeuronal acetylcholine receptor subunit alpha-2target
EthanolGamma-aminobutyric acid receptor subunit alpha-6target
EthanolGlutamate receptor 2target
EthanolGlutamate receptor 4target
EthanolGlutamate receptor 3target
EthanolNeuronal acetylcholine receptor subunit alpha-4target
EthanolNeuronal acetylcholine receptor subunit beta-2target
EthanolG protein-activated inward rectifier potassium channel 1target
EthanolG protein-activated inward rectifier potassium channel 2target
EthanolVascular cell adhesion protein 1target
EthanolEquilibrative nucleoside transporter 1target
EthanolG protein-activated inward rectifier potassium channel 4target
EthanolNeuronal acetylcholine receptor subunit alpha-7target
EthanolNeuronal acetylcholine receptor subunit alpha-9target
EthanolGamma-aminobutyric acid receptor subunit beta-1target
EthanolGamma-aminobutyric acid receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit beta-2target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
EthanolAlcohol dehydrogenase 6enzyme
EthanolNeuronal acetylcholine receptor subunit beta-4target
EthanolNeuronal acetylcholine receptor subunit alpha-3target
EthanolNeuronal acetylcholine receptor subunit alpha-5target
EthanolNeuronal acetylcholine receptor subunit alpha-6target
EthanolNeuronal acetylcholine receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit gamma-1target
EthanolGamma-aminobutyric acid receptor subunit gamma-3target
EthanolGamma-aminobutyric acid receptor subunit epsilontarget
EthanolGamma-aminobutyric acid receptor subunit pitarget
EthanolGamma-aminobutyric acid receptor subunit thetatarget
EthanolGamma-aminobutyric acid receptor subunit deltatarget
EthanolAlcohol dehydrogenase [NADP(+)]enzyme
EthanolEquilibrative nucleoside transporter 2target
Ethanol5-hydroxytryptamine receptor 3Etarget
Ethanol5-hydroxytryptamine receptor 3Btarget
Ethanol5-hydroxytryptamine receptor 3Dtarget
Ethanol5-hydroxytryptamine receptor 3Ctarget
EthanolVoltage-dependent calcium channel gamma-2 subunittarget
EthanolG protein-activated inward rectifier potassium channel 3target
EthanolNeural cell adhesion molecule L1target
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
CetrimoniumCyclopropane mycolic acid synthase MmaA2target
CetrimoniumCyclopropane mycolic acid synthase 1target
Isopropyl alcoholGTP cyclohydrolase 1target
Isopropyl alcoholSubtilisin BPN'target
Isopropyl alcoholRibonuclease pancreatictarget
Isopropyl alcoholTrypsin-2target
Isopropyl alcoholAldehyde oxidoreductasetarget
Isopropyl alcoholGanglioside GM2 activatortarget
Isopropyl alcoholThermolysintarget
Isopropyl alcoholChitotriosidase-1target
Isopropyl alcoholAdenosylhomocysteinasetarget
Isopropyl alcoholSpliceosome RNA helicase DDX39Btarget
Isopropyl alcoholDNA mismatch repair protein MutLtarget
Isopropyl alcoholGag-Pro-Pol polyproteintarget
Isopropyl alcoholLysozymetarget
Isopropyl alcoholGlucarate dehydratasetarget
Isopropyl alcoholmRNA-capping enzymetarget
Isopropyl alcoholFMN-dependent NADH-azoreductasetarget
Isopropyl alcoholTranscription termination/antitermination protein NusGtarget
Isopropyl alcohol1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenasetarget
Isopropyl alcoholGrowth/differentiation factor 5target
Isopropyl alcoholIg kappa chain V-IV region Lentarget
Isopropyl alcoholPectate lyasetarget
Isopropyl alcoholGag polyproteintarget
Isopropyl alcoholPhospholipase A2, membrane associatedtarget
Isopropyl alcoholScaffolding dockerin binding protein Atarget
Isopropyl alcoholAlr1529 proteintarget
Isopropyl alcoholL-xylulose reductasetarget
Isopropyl alcoholPeroxiredoxin-6target
Isopropyl alcoholHydrolase, TatD familytarget
Isopropyl alcoholTumor necrosis factortarget
Isopropyl alcoholTartrate-resistant acid phosphatase type 5target
Lactic acidBifunctional protein PutAtarget
Lactic acidNimA-related proteintarget
Lactic acidMonocarboxylate transporter 2transporter
Lactic acidSolute carrier organic anion transporter family member 2B1transporter
Lactic acidMonocarboxylate transporter 1transporter
Lactic acidMonocarboxylate transporter 10transporter
Lactic acidSolute carrier organic anion transporter family member 2A1transporter
Lactic acidMonocarboxylate transporter 4transporter
Silver sulfadiazineDNAtarget
IodineSodium/iodide cotransportertransporter
IodineSerum albumincarrier
IodineThyroglobulincarrier
IodineThyroid peroxidaseenzyme
IodineSodium/iodide cotransportertarget
IodinePendrintransporter
IodineMicrobial proteinstarget
TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
TriclosanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
TriclosanNuclear receptor subfamily 1 group I member 2target
TriclosanAndrogen receptortarget
TriclosanNuclear receptor subfamily 1 group I member 3target
TriclosanPeroxisome proliferator-activated receptor gammatarget
TriclosanThyroid peroxidasetarget
TriclocarbanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
TriclocarbanCytochrome P450 1A1enzyme
TriclocarbanCytochrome P450 1B1enzyme