Piritramide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Piritramide
Accession Number
DB12492
Type
Small Molecule
Groups
Investigational
Description

Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.

Structure
Thumb
Synonyms
Not Available
External IDs
IDS-NP-013 / R 3365
Categories
UNII
4RP92LYZ2F
CAS number
302-41-0
Weight
Average: 430.5851
Monoisotopic: 430.27326173
Chemical Formula
C27H34N4O
InChI Key
IHEHEFLXQFOQJO-UHFFFAOYSA-N
InChI
InChI=1S/C27H34N4O/c28-22-26(23-10-4-1-5-11-23,24-12-6-2-7-13-24)14-19-30-20-15-27(16-21-30,25(29)32)31-17-8-3-9-18-31/h1-2,4-7,10-13H,3,8-9,14-21H2,(H2,29,32)
IUPAC Name
1-(3-cyano-3,3-diphenylpropyl)-4-(piperidin-1-yl)piperidine-4-carboximidic acid
SMILES
OC(=N)C1(CCN(CCC(C#N)(C2=CC=CC=C2)C2=CC=CC=C2)CC1)N1CCCCC1

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
2,5-Dimethoxy-4-ethylamphetamine2,5-Dimethoxy-4-ethylamphetamine may increase the analgesic activities of Piritramide.Experimental, Illicit
3,4-Methylenedioxyamphetamine3,4-Methylenedioxyamphetamine may increase the analgesic activities of Piritramide.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamine4-Bromo-2,5-dimethoxyamphetamine may increase the analgesic activities of Piritramide.Experimental, Illicit
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Piritramide.Experimental
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of adverse effects can be increased when Piritramide is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Piritramide.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Piritramide.Approved
AcetazolamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Acetazolamide.Approved, Vet Approved
AclidiniumThe risk or severity of adverse effects can be increased when Aclidinium is combined with Piritramide.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Piritramide.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Piritramide.Approved, Investigational
AlaproclatePiritramide may increase the serotonergic activities of Alaproclate.Experimental
AlcuroniumThe risk or severity of adverse effects can be increased when Alcuronium is combined with Piritramide.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Piritramide.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Piritramide.Approved, Illicit
AlimemazineAlimemazine may increase the hypotensive activities of Piritramide.Approved, Vet Approved
AllopregnanoloneThe risk or severity of adverse effects can be increased when Allopregnanolone is combined with Piritramide.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Piritramide.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Piritramide is combined with Alphaprodine.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Piritramide.Approved, Illicit, Investigational
AlvimopanThe risk or severity of adverse effects can be increased when Piritramide is combined with Alvimopan.Approved
AmilorideThe risk or severity of adverse effects can be increased when Piritramide is combined with Amiloride.Approved
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Piritramide.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Piritramide is combined with Amitriptyline.Approved
Ammonium chlorideAmmonium chloride may increase the excretion rate of Piritramide which could result in a lower serum level and potentially a reduction in efficacy.Approved, Vet Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Piritramide.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Piritramide is combined with Amoxapine.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Piritramide.Experimental
AmphetamineAmphetamine may increase the analgesic activities of Piritramide.Approved, Illicit
Anisotropine MethylbromideThe risk or severity of adverse effects can be increased when Anisotropine Methylbromide is combined with Piritramide.Approved
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Piritramide.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Piritramide.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Piritramide.Approved
AtracuriumThe risk or severity of adverse effects can be increased when Atracurium is combined with Piritramide.Experimental
Atracurium besylateThe risk or severity of adverse effects can be increased when Atracurium besylate is combined with Piritramide.Approved
AtropineThe risk or severity of adverse effects can be increased when Atropine is combined with Piritramide.Approved, Vet Approved
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Piritramide.Vet Approved
AzelastinePiritramide may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
AzosemideThe risk or severity of adverse effects can be increased when Piritramide is combined with Azosemide.Investigational
BaclofenThe risk or severity of adverse effects can be increased when Piritramide is combined with Baclofen.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Piritramide.Illicit
BenactyzineThe risk or severity of adverse effects can be increased when Benactyzine is combined with Piritramide.Withdrawn
BendroflumethiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Bendroflumethiazide.Approved
BenmoxinThe risk or severity of adverse effects can be increased when Piritramide is combined with Benmoxin.Withdrawn
BenperidolThe risk or severity of adverse effects can be increased when Piritramide is combined with Benperidol.Investigational
BenzatropineThe risk or severity of adverse effects can be increased when Benzatropine is combined with Piritramide.Approved
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with Piritramide.Approved
BenzphetamineBenzphetamine may increase the analgesic activities of Piritramide.Approved, Illicit
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Piritramide.Approved
BiperidenThe risk or severity of adverse effects can be increased when Biperiden is combined with Piritramide.Approved
BL-1020BL-1020 may increase the hypotensive activities of Piritramide.Investigational
BornaprineThe risk or severity of adverse effects can be increased when Bornaprine is combined with Piritramide.Experimental
BrexpiprazoleThe risk or severity of adverse effects can be increased when Piritramide is combined with Brexpiprazole.Approved
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved
BrofaromineThe risk or severity of adverse effects can be increased when Piritramide is combined with Brofaromine.Experimental
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Piritramide.Approved, Illicit
BromisovalThe risk or severity of adverse effects can be increased when Piritramide is combined with Bromisoval.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Bromperidol is combined with Piritramide.Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Brompheniramine.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Piritramide.Approved, Withdrawn
BumetanideThe risk or severity of adverse effects can be increased when Piritramide is combined with Bumetanide.Approved
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Piritramide.Approved, Investigational
BuprenorphinePiritramide may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Piritramide.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Piritramide.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Butacaine is combined with Piritramide.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Piritramide is combined with Butalbital.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Butamben is combined with Piritramide.Approved
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Piritramide.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Piritramide.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Piritramide.Investigational
Canrenoic acidThe risk or severity of adverse effects can be increased when Piritramide is combined with Canrenoic acid.Approved, Withdrawn
CanrenoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Canrenone.Investigational
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Piritramide.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Piritramide is combined with Carbinoxamine.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Piritramide.Illicit, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Piritramide is combined with Carisoprodol.Approved
CaroxazoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Caroxazone.Withdrawn
CetirizineThe risk or severity of adverse effects can be increased when Piritramide is combined with Cetirizine.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Piritramide.Approved, Illicit, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Piritramide.Approved, Illicit
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Piritramide.Approved, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Piritramide.Approved
ChlorothiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Chlorothiazide.Approved, Vet Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Piritramide is combined with Chlorphenamine.Approved
ChlorphenoxamineThe risk or severity of adverse effects can be increased when Chlorphenoxamine is combined with Piritramide.Withdrawn
ChlorphentermineChlorphentermine may increase the analgesic activities of Piritramide.Illicit, Withdrawn
ChlorproethazineChlorproethazine may increase the hypotensive activities of Piritramide.Experimental
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Piritramide.Approved, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Piritramide.Approved, Withdrawn
ChlorthalidoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Chlorthalidone.Approved
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Chlorzoxazone.Approved
CicletanineThe risk or severity of adverse effects can be increased when Piritramide is combined with Cicletanine.Investigational
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Piritramide.Approved, Vet Approved
CitalopramPiritramide may increase the serotonergic activities of Citalopram.Approved
ClemastineThe risk or severity of adverse effects can be increased when Piritramide is combined with Clemastine.Approved
ClidiniumThe risk or severity of adverse effects can be increased when Piritramide is combined with Clidinium.Approved
ClobazamThe risk or severity of adverse effects can be increased when Piritramide is combined with Clobazam.Approved, Illicit
ClofenamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Clofenamide.Experimental
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Piritramide.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Clomipramine.Approved, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Piritramide is combined with Clonazepam.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Piritramide is combined with Clonidine.Approved
ClopamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Clopamide.Experimental
ClopenthixolThe risk or severity of adverse effects can be increased when Piritramide is combined with Clopenthixol.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Piritramide.Approved, Illicit
ClorexoloneThe risk or severity of adverse effects can be increased when Piritramide is combined with Clorexolone.Experimental
ClothiapineThe risk or severity of adverse effects can be increased when Piritramide is combined with Clothiapine.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Piritramide.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Piritramide.Approved, Illicit
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Piritramide.Approved, Illicit
ConivaptanThe risk or severity of adverse effects can be increased when Piritramide is combined with Conivaptan.Approved, Investigational
CyclizineThe risk or severity of adverse effects can be increased when Piritramide is combined with Cyclizine.Approved
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Piritramide.Approved
CyclopenthiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Cyclopenthiazide.Experimental
CyclopentolateThe risk or severity of adverse effects can be increased when Cyclopentolate is combined with Piritramide.Approved
CyclothiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Cyclothiazide.Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Piritramide is combined with Cyproheptadine.Approved
DantroleneThe risk or severity of adverse effects can be increased when Piritramide is combined with Dantrolene.Approved
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Piritramide.Approved
DapoxetinePiritramide may increase the serotonergic activities of Dapoxetine.Investigational
DarifenacinThe risk or severity of adverse effects can be increased when Darifenacin is combined with Piritramide.Approved, Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Piritramide.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Piritramide.Approved
DesipramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Desipramine.Approved
DesloratadineThe risk or severity of adverse effects can be increased when Piritramide is combined with Desloratadine.Approved, Investigational
DesmopressinThe risk or severity of adverse effects can be increased when Piritramide is combined with Desmopressin.Approved
DesvenlafaxinePiritramide may increase the serotonergic activities of Desvenlafaxine.Approved
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Piritramide.Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Dexbrompheniramine.Approved
DexetimideThe risk or severity of adverse effects can be increased when Dexetimide is combined with Piritramide.Withdrawn
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Piritramide.Approved, Vet Approved
DextroamphetamineDextroamphetamine may increase the analgesic activities of Piritramide.Approved, Illicit
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Piritramide.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Piritramide.Approved, Illicit, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Piritramide.Approved
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Piritramide.Approved, Illicit, Vet Approved
DicyclomineThe risk or severity of adverse effects can be increased when Dicyclomine is combined with Piritramide.Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Piritramide is combined with Diethyl ether.Experimental
DiethylpropionDiethylpropion may increase the analgesic activities of Piritramide.Approved, Illicit
DifenoxinThe risk or severity of adverse effects can be increased when Piritramide is combined with Difenoxin.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Piritramide.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Piritramide.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Piritramide.Experimental, Illicit
DimenhydrinateThe risk or severity of adverse effects can be increased when Piritramide is combined with Dimenhydrinate.Approved
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Piritramide.Approved
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Piritramide.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Dixyrazine.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Piritramide.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Piritramide is combined with Doxepin.Approved
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Piritramide.Investigational
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Vet Approved
DrospirenoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Drospirenone.Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Piritramide.Experimental, Illicit
DuloxetinePiritramide may increase the serotonergic activities of Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Piritramide.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Piritramide.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Ecopipam is combined with Piritramide.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Piritramide is combined with Efavirenz.Approved, Investigational
EfonidipineThe risk or severity of adverse effects can be increased when Piritramide is combined with Efonidipine.Approved
EltanoloneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Piritramide.Investigational
EluxadolinePiritramide may increase the constipating activities of Eluxadoline.Approved
EmeproniumThe risk or severity of adverse effects can be increased when Emepronium is combined with Piritramide.Experimental
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Piritramide.Approved, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Piritramide is combined with Entacapone.Approved, Investigational
EplerenoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Eplerenone.Approved
EscitalopramPiritramide may increase the serotonergic activities of Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Piritramide.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Piritramide.Approved
Etacrynic acidThe risk or severity of adverse effects can be increased when Piritramide is combined with Etacrynic acid.Approved
EtanautineThe risk or severity of adverse effects can be increased when Etanautine is combined with Piritramide.Experimental
EthanolPiritramide may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Piritramide.Approved, Illicit, Withdrawn
EthopropazineThe risk or severity of adverse effects can be increased when Ethopropazine is combined with Piritramide.Approved
EthosuximideThe risk or severity of adverse effects can be increased when Piritramide is combined with Ethosuximide.Approved
EthotoinThe risk or severity of adverse effects can be increased when Piritramide is combined with Ethotoin.Approved
EthoxzolamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Ethoxzolamide.Withdrawn
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Piritramide.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Piritramide is combined with Ethyl chloride.Experimental
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Piritramide.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Piritramide.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Piritramide.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Piritramide.Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Piritramide.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Piritramide.Approved
EtoperidonePiritramide may increase the serotonergic activities of Etoperidone.Approved
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Piritramide.Illicit, Vet Approved
EtybenzatropineThe risk or severity of adverse effects can be increased when Etybenzatropine is combined with Piritramide.Experimental
EzogabineThe risk or severity of adverse effects can be increased when Piritramide is combined with Ezogabine.Approved
FelbamateThe risk or severity of adverse effects can be increased when Piritramide is combined with Felbamate.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Piritramide.Approved, Illicit, Withdrawn
FenquizoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Fenquizone.Experimental
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Piritramide.Approved, Illicit, Investigational, Vet Approved
FesoterodineThe risk or severity of adverse effects can be increased when Fesoterodine is combined with Piritramide.Approved
FexofenadineThe risk or severity of adverse effects can be increased when Piritramide is combined with Fexofenadine.Approved
FlibanserinThe risk or severity of adverse effects can be increased when Piritramide is combined with Flibanserin.Approved
FluanisoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Fluanisone.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Piritramide.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Piritramide is combined with Flunarizine.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Piritramide.Approved, Illicit
FluoxetinePiritramide may increase the serotonergic activities of Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Piritramide.Approved, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Piritramide.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Piritramide.Approved, Illicit
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Piritramide.Approved
Fluticasone propionateThe risk or severity of adverse effects can be increased when Piritramide is combined with Fluticasone propionate.Approved
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Piritramide.Approved, Investigational
FosphenytoinThe risk or severity of adverse effects can be increased when Piritramide is combined with Fosphenytoin.Approved
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Piritramide.Approved, Illicit
FurazolidoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Furazolidone.Approved, Vet Approved
FurosemideThe risk or severity of adverse effects can be increased when Piritramide is combined with Furosemide.Approved, Vet Approved
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Piritramide.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Piritramide is combined with Gabapentin Enacarbil.Approved
GallamineThe risk or severity of adverse effects can be increased when Gallamine is combined with Piritramide.Experimental
Gallamine TriethiodideThe risk or severity of adverse effects can be increased when Gallamine Triethiodide is combined with Piritramide.Approved
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Piritramide.Approved, Illicit
GepefrineGepefrine may increase the analgesic activities of Piritramide.Experimental
GepironeThe risk or severity of adverse effects can be increased when Gepirone is combined with Piritramide.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Piritramide.Approved, Illicit
GlycopyrroniumThe risk or severity of adverse effects can be increased when Glycopyrronium is combined with Piritramide.Approved, Investigational, Vet Approved
GuanfacineThe risk or severity of adverse effects can be increased when Piritramide is combined with Guanfacine.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Piritramide.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Piritramide.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Piritramide.Approved, Vet Approved
HarmalineThe risk or severity of adverse effects can be increased when Piritramide is combined with Harmaline.Experimental
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Piritramide.Approved, Illicit
HexamethoniumThe risk or severity of adverse effects can be increased when Hexamethonium is combined with Piritramide.Experimental
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Piritramide.Approved
HomatropineThe risk or severity of adverse effects can be increased when Homatropine is combined with Piritramide.Approved
HydracarbazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Hydracarbazine.Experimental
HydrochlorothiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Hydrochlorothiazide.Approved, Vet Approved
HydrocodonePiritramide may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydroflumethiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Hydroflumethiazide.Approved
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Piritramide.Approved, Illicit
HydroxyamphetamineHydroxyamphetamine may increase the analgesic activities of Piritramide.Approved
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved
HyoscyamineThe risk or severity of adverse effects can be increased when Hyoscyamine is combined with Piritramide.Approved
IbopamineThe risk or severity of adverse effects can be increased when Piritramide is combined with Ibopamine.Experimental
IloperidoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Iloperidone.Approved
ImipramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Imipramine.Approved
IndalpinePiritramide may increase the serotonergic activities of Indalpine.Investigational, Withdrawn
IndapamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Indapamide.Approved
IndiplonThe risk or severity of adverse effects can be increased when Piritramide is combined with Indiplon.Investigational
Iofetamine I-123Iofetamine I-123 may increase the analgesic activities of Piritramide.Approved
Ipratropium bromideThe risk or severity of adverse effects can be increased when Ipratropium bromide is combined with Piritramide.Approved
IproclozideThe risk or severity of adverse effects can be increased when Piritramide is combined with Iproclozide.Withdrawn
IproniazidThe risk or severity of adverse effects can be increased when Piritramide is combined with Iproniazid.Withdrawn
IsocarboxazidThe risk or severity of adverse effects can be increased when Piritramide is combined with Isocarboxazid.Approved
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Piritramide.Approved, Vet Approved
IsosorbideThe risk or severity of adverse effects can be increased when Piritramide is combined with Isosorbide.Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Piritramide.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Piritramide.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Piritramide.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Piritramide is combined with Lamotrigine.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Piritramide is combined with Levetiracetam.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Piritramide.Approved
LevocabastineThe risk or severity of adverse effects can be increased when Piritramide is combined with Levocabastine.Approved
LevocetirizineThe risk or severity of adverse effects can be increased when Piritramide is combined with Levocetirizine.Approved
LevodopaThe risk or severity of adverse effects can be increased when Piritramide is combined with Levodopa.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Piritramide.Approved
LevomilnacipranPiritramide may increase the serotonergic activities of Levomilnacipran.Approved
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Piritramide.Approved
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Piritramide.Approved, Vet Approved
LisdexamfetamineLisdexamfetamine may increase the analgesic activities of Piritramide.Approved, Investigational
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with Piritramide.Approved
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Piritramide.Illicit
LoprazolamThe risk or severity of adverse effects can be increased when Piritramide is combined with Loprazolam.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Piritramide is combined with Loratadine.Approved
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Piritramide.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Piritramide is combined with Lormetazepam.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Piritramide.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Piritramide.Approved
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Vet Approved
MannitolThe risk or severity of adverse effects can be increased when Piritramide is combined with Mannitol.Approved, Investigational
MaprotilineThe risk or severity of adverse effects can be increased when Piritramide is combined with Maprotiline.Approved
MazaticolThe risk or severity of adverse effects can be increased when Mazaticol is combined with Piritramide.Experimental
MebanazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Mebanazine.Withdrawn
MebicarThe risk or severity of adverse effects can be increased when Piritramide is combined with Mebicar.Experimental
MebutizideThe risk or severity of adverse effects can be increased when Piritramide is combined with Mebutizide.Experimental
MecamylamineThe risk or severity of adverse effects can be increased when Mecamylamine is combined with Piritramide.Approved
MeclizineThe risk or severity of adverse effects can be increased when Piritramide is combined with Meclizine.Approved
MedazepamThe risk or severity of adverse effects can be increased when Piritramide is combined with Medazepam.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Piritramide.Vet Approved
MefrusideThe risk or severity of adverse effects can be increased when Piritramide is combined with Mefruside.Experimental
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Piritramide.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Piritramide.Approved
MephedroneMephedrone may increase the analgesic activities of Piritramide.Investigational
MephentermineMephentermine may increase the analgesic activities of Piritramide.Approved
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Piritramide.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Piritramide.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Piritramide is combined with Meptazinol.Experimental
MersalylThe risk or severity of adverse effects can be increased when Piritramide is combined with Mersalyl.Approved
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Piritramide.Approved
MetaxaloneThe risk or severity of adverse effects can be increased when Piritramide is combined with Metaxalone.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Piritramide.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Piritramide.Approved, Illicit
MethamphetamineMethamphetamine may increase the analgesic activities of Piritramide.Approved, Illicit
MethanthelineThe risk or severity of adverse effects can be increased when Methantheline is combined with Piritramide.Approved
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Piritramide.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Piritramide.Illicit, Withdrawn
MethazolamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Methazolamide.Approved
MethocarbamolThe risk or severity of adverse effects can be increased when Piritramide is combined with Methocarbamol.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Piritramide.Approved
MethotrimeprazinePiritramide may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Piritramide.Approved, Vet Approved
MethoxyphenamineMethoxyphenamine may increase the analgesic activities of Piritramide.Experimental
MethsuximideThe risk or severity of adverse effects can be increased when Piritramide is combined with Methsuximide.Approved
MethyclothiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Methyclothiazide.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Piritramide.Experimental
Methylene blueMethylene blue may increase the hypotensive activities of Piritramide.Investigational
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Piritramide.Approved
MeticraneThe risk or severity of adverse effects can be increased when Piritramide is combined with Meticrane.Experimental
MetixeneThe risk or severity of adverse effects can be increased when Metixene is combined with Piritramide.Approved
MetolazoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Metolazone.Approved
MetyrosinePiritramide may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Piritramide.Approved, Illicit
Midomafetamine3,4-Methylenedioxymethamphetamine may increase the analgesic activities of Piritramide.Experimental, Illicit
MilnacipranPiritramide may increase the serotonergic activities of Milnacipran.Approved
MinaprineThe risk or severity of adverse effects can be increased when Piritramide is combined with Minaprine.Approved
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Investigational
MirtazapinePiritramide may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MMDAMMDA may increase the analgesic activities of Piritramide.Experimental, Illicit
MoclobemideThe risk or severity of adverse effects can be increased when Piritramide is combined with Moclobemide.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Piritramide.Approved
MoricizineMoricizine may increase the hypotensive activities of Piritramide.Approved, Withdrawn
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Piritramide.Approved, Investigational
MuzolimineThe risk or severity of adverse effects can be increased when Piritramide is combined with Muzolimine.Experimental
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Piritramide.Approved
NaltrexoneThe therapeutic efficacy of Piritramide can be decreased when used in combination with Naltrexone.Approved, Investigational, Vet Approved
NefazodonePiritramide may increase the serotonergic activities of Nefazodone.Approved, Withdrawn
NialamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Nialamide.Withdrawn
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Piritramide.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Piritramide.Approved, Vet Approved
NorfluraneThe risk or severity of adverse effects can be increased when Piritramide is combined with Norflurane.Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Piritramide.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Piritramide is combined with Nortriptyline.Approved
OctamoxinThe risk or severity of adverse effects can be increased when Piritramide is combined with Octamoxin.Withdrawn
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Piritramide.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Piritramide is combined with Olopatadine.Approved
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Piritramide.Approved
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Piritramide.Approved, Illicit
OrphenadrinePiritramide may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Piritramide.Investigational
OtiloniumThe risk or severity of adverse effects can be increased when Otilonium is combined with Piritramide.Experimental
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Piritramide.Approved
OxethazaineThe risk or severity of adverse effects can be increased when Piritramide is combined with Oxethazaine.Investigational
OxitropiumThe risk or severity of adverse effects can be increased when Oxitropium is combined with Piritramide.Investigational
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Piritramide.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Piritramide.Approved
OxybutyninThe risk or severity of adverse effects can be increased when Oxybutynin is combined with Piritramide.Approved, Investigational
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Piritramide.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Piritramide.Approved, Investigational, Vet Approved
OxyphenoniumThe risk or severity of adverse effects can be increased when Oxyphenonium is combined with Piritramide.Approved
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Piritramide.Approved
PancuroniumThe risk or severity of adverse effects can be increased when Pancuronium is combined with Piritramide.Approved
ParaldehydePiritramide may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved
PargylineThe risk or severity of adverse effects can be increased when Piritramide is combined with Pargyline.Approved
ParoxetinePiritramide may increase the serotonergic activities of Paroxetine.Approved, Investigational
PegvisomantThe therapeutic efficacy of Pegvisomant can be decreased when used in combination with Piritramide.Approved
PenfluridolThe risk or severity of adverse effects can be increased when Piritramide is combined with Penfluridol.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Piritramide.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Piritramide.Approved, Vet Approved
PentoliniumThe risk or severity of adverse effects can be increased when Pentolinium is combined with Piritramide.Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved
PerazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Perazine.Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Piritramide.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Piritramide.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Piritramide.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenazocine.Experimental
PhenelzineThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenelzine.Approved
PhenglutarimideThe risk or severity of adverse effects can be increased when Phenglutarimide is combined with Piritramide.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenibut.Experimental
PheniprazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Pheniprazine.Withdrawn
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Piritramide.Approved
PhenoperidineThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenoperidine.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Phenoxyethanol is combined with Piritramide.Approved
PhenoxypropazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenoxypropazine.Withdrawn
PhenterminePhentermine may increase the analgesic activities of Piritramide.Approved, Illicit
PhenytoinThe risk or severity of adverse effects can be increased when Piritramide is combined with Phenytoin.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Piritramide.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Piritramide.Approved
PipecuroniumThe risk or severity of adverse effects can be increased when Pipecuronium is combined with Piritramide.Approved
PipotiazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Pipotiazine.Approved
PirenzepineThe risk or severity of adverse effects can be increased when Pirenzepine is combined with Piritramide.Approved
PiretanideThe risk or severity of adverse effects can be increased when Piritramide is combined with Piretanide.Experimental
PirlindoleThe risk or severity of adverse effects can be increased when Piritramide is combined with Pirlindole.Approved
PivhydrazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Pivhydrazine.Withdrawn
PizotifenThe risk or severity of adverse effects can be increased when Piritramide is combined with Pizotifen.Approved
PolythiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Polythiazide.Approved
PomalidomideThe risk or severity of adverse effects can be increased when Piritramide is combined with Pomalidomide.Approved
PotassiumThe risk or severity of adverse effects can be increased when Piritramide is combined with Potassium.Approved
Potassium CitrateThe risk or severity of adverse effects can be increased when Piritramide is combined with Potassium Citrate.Approved, Vet Approved
PramipexolePiritramide may increase the sedative activities of Pramipexole.Approved, Investigational
PramocaineThe risk or severity of adverse effects can be increased when Pramocaine is combined with Piritramide.Approved
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Piritramide.Approved, Illicit
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Piritramide.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Piritramide.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Primidone.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Piritramide.Approved, Investigational, Vet Approved
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Piritramide.Approved, Vet Approved
ProcyclidineThe risk or severity of adverse effects can be increased when Procyclidine is combined with Piritramide.Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Piritramide.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Promethazine.Approved
PropanididThe risk or severity of adverse effects can be increased when Piritramide is combined with Propanidid.Experimental
PropanthelineThe risk or severity of adverse effects can be increased when Propantheline is combined with Piritramide.Approved
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Piritramide.Approved, Vet Approved
PropiopromazinePropiopromazine may increase the hypotensive activities of Piritramide.Vet Approved
PropiverineThe risk or severity of adverse effects can be increased when Propiverine is combined with Piritramide.Investigational
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Piritramide.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Piritramide.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Piritramide is combined with Protriptyline.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Piritramide is combined with Proxibarbal.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Piritramide.Investigational
PseudoephedrinePseudoephedrine may increase the analgesic activities of Piritramide.Approved
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Piritramide.Approved, Illicit
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Piritramide.Approved
QuinethazoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Quinethazone.Approved
QuinidineThe risk or severity of adverse effects can be increased when Quinidine is combined with Piritramide.Approved
QuinisocaineThe risk or severity of adverse effects can be increased when Piritramide is combined with Quinisocaine.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Piritramide is combined with Raclopride.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Piritramide is combined with Ramelteon.Approved, Investigational
RamosetronPiritramide may increase the constipating activities of Ramosetron.Approved
RasagilineThe risk or severity of adverse effects can be increased when Piritramide is combined with Rasagiline.Approved
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Piritramide.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Piritramide.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Piritramide.Approved
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Piritramide.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Piritramide is combined with Ritanserin.Investigational
RitobegronRitobegron may increase the analgesic activities of Piritramide.Investigational
RolofyllineThe risk or severity of adverse effects can be increased when Piritramide is combined with Rolofylline.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Piritramide.Vet Approved
RopinirolePiritramide may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Piritramide.Approved
RotigotinePiritramide may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Piritramide.Approved
SafrazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Safrazine.Withdrawn
ScopolamineThe risk or severity of adverse effects can be increased when Piritramide is combined with Scopolamine.Approved
Scopolamine butylbromideThe risk or severity of adverse effects can be increased when Scopolamine butylbromide is combined with Piritramide.Approved, Vet Approved
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Piritramide.Approved, Vet Approved
SelegilineThe risk or severity of adverse effects can be increased when Piritramide is combined with Selegiline.Approved, Investigational, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Piritramide is combined with Sepranolone.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Piritramide.Approved, Withdrawn
SertralinePiritramide may increase the serotonergic activities of Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Piritramide.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved
SolifenacinThe risk or severity of adverse effects can be increased when Solifenacin is combined with Piritramide.Approved
SpiradolineThe risk or severity of adverse effects can be increased when Piritramide is combined with Spiradoline.Investigational
SpironolactoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Spironolactone.Approved
StiripentolThe risk or severity of adverse effects can be increased when Piritramide is combined with Stiripentol.Approved
SuccinylcholineSuccinylcholine may increase the bradycardic activities of Piritramide.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Piritramide.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Piritramide.Approved
SultoprideThe risk or severity of adverse effects can be increased when Piritramide is combined with Sultopride.Experimental
SuvorexantPiritramide may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved
TandospironeThe risk or severity of adverse effects can be increased when Piritramide is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Piritramide.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Piritramide is combined with Tasimelteon.Approved
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Piritramide.Approved
TetrabenazineThe risk or severity of adverse effects can be increased when Piritramide is combined with Tetrabenazine.Approved
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Piritramide.Approved, Vet Approved
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Tetrahydropalmatine is combined with Piritramide.Investigational
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Piritramide.Investigational
ThalidomidePiritramide may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
TheobromineThe risk or severity of adverse effects can be increased when Piritramide is combined with Theobromine.Approved
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Piritramide.Approved, Vet Approved
ThiazinamThiazinam may increase the hypotensive activities of Piritramide.Experimental
ThiethylperazineThiethylperazine may increase the hypotensive activities of Piritramide.Withdrawn
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Piritramide.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Piritramide.Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Piritramide.Approved
TiagabineThe risk or severity of adverse effects can be increased when Piritramide is combined with Tiagabine.Approved
TiaprideThe risk or severity of adverse effects can be increased when Piritramide is combined with Tiapride.Approved, Investigational
TicrynafenThe risk or severity of adverse effects can be increased when Piritramide is combined with Ticrynafen.Withdrawn
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Piritramide.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Piritramide is combined with Tilidine.Experimental
TiotropiumThe risk or severity of adverse effects can be increased when Tiotropium is combined with Piritramide.Approved
TizanidineThe risk or severity of adverse effects can be increased when Piritramide is combined with Tizanidine.Approved
TolcaponeThe risk or severity of adverse effects can be increased when Piritramide is combined with Tolcapone.Approved, Withdrawn
ToloxatoneThe risk or severity of adverse effects can be increased when Piritramide is combined with Toloxatone.Approved
TolterodineThe risk or severity of adverse effects can be increased when Tolterodine is combined with Piritramide.Approved, Investigational
TolvaptanThe risk or severity of adverse effects can be increased when Piritramide is combined with Tolvaptan.Approved
TopiramateThe risk or severity of adverse effects can be increased when Piritramide is combined with Topiramate.Approved
TorasemideThe risk or severity of adverse effects can be increased when Piritramide is combined with Torasemide.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Piritramide.Approved, Investigational
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Trans-2-Phenylcyclopropylamine is combined with Piritramide.Experimental
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Piritramide.Approved
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Piritramide.Approved, Investigational
TriamtereneThe risk or severity of adverse effects can be increased when Piritramide is combined with Triamterene.Approved
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Piritramide.Approved
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Tricaine methanesulfonate is combined with Piritramide.Vet Approved
TrichlormethiazideThe risk or severity of adverse effects can be increased when Piritramide is combined with Trichlormethiazide.Approved, Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Piritramide is combined with Trichloroethylene.Experimental
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Piritramide.Approved
TrifluperidolThe risk or severity of adverse effects can be increased when Piritramide is combined with Trifluperidol.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Piritramide.Approved, Vet Approved
TrihexyphenidylThe risk or severity of adverse effects can be increased when Trihexyphenidyl is combined with Piritramide.Approved
TrimethaphanThe risk or severity of adverse effects can be increased when Trimethaphan is combined with Piritramide.Approved
TrimipramineThe risk or severity of adverse effects can be increased when Piritramide is combined with Trimipramine.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Piritramide is combined with Triprolidine.Approved
TropatepineThe risk or severity of adverse effects can be increased when Tropatepine is combined with Piritramide.Experimental
TropicamideThe risk or severity of adverse effects can be increased when Tropicamide is combined with Piritramide.Approved
TrospiumThe risk or severity of adverse effects can be increased when Trospium is combined with Piritramide.Approved
TubocurarineThe risk or severity of adverse effects can be increased when Tubocurarine is combined with Piritramide.Approved
UlaritideThe risk or severity of adverse effects can be increased when Piritramide is combined with Ularitide.Investigational
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Piritramide.Approved, Investigational
VecuroniumThe risk or severity of adverse effects can be increased when Vecuronium is combined with Piritramide.Approved
VenlafaxinePiritramide may increase the serotonergic activities of Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Piritramide is combined with Veralipride.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Piritramide is combined with Vigabatrin.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Piritramide is combined with Vinyl ether.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Piritramide.Approved
XenonThe risk or severity of adverse effects can be increased when Piritramide is combined with Xenon.Experimental
XipamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Xipamide.Experimental
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Piritramide.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Piritramide.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Piritramide is combined with Ziconotide.Approved
ZimelidinePiritramide may increase the serotonergic activities of Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Piritramide.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Piritramide.Vet Approved
ZolpidemPiritramide may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Piritramide is combined with Zonisamide.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Piritramide.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Piritramide.Approved
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Piritramide.Approved, Investigational
Food Interactions
Not Available

References

Synthesis Reference
Not Available
General References
Not Available
External Links
Human Metabolome Database
HMDB41990
ChemSpider
8967
ChEBI
135699
ChEMBL
CHEMBL559288
ATC Codes
N02AC03 — Piritramide
AHFS Codes
Not Available
PDB Entries
Not Available
FDA label
Not Available
MSDS
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedSupportive CarePostoperative pain / Prophylaxis against postoperative nausea and vomiting1
4RecruitingTreatmentMalignant Neoplasm of Colon / Minimal Residual Disease1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0185 mg/mLALOGPS
logP3.58ALOGPS
logP1.45ChemAxon
logS-4.4ALOGPS
pKa (Strongest Acidic)2.71ChemAxon
pKa (Strongest Basic)9.44ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area74.35 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity150.74 m3·mol-1ChemAxon
Polarizability49.27 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of chemical entities known as diphenylacetonitriles. These are cyclic aromatic compounds containing a diphenylacetonitrile moiety, which consists of a diphenylmethane linked to and acetonitrile to form 2,2-diphenylacetonitrile.
Kingdom
Chemical entities
Super Class
Organic compounds
Class
Benzenoids
Sub Class
Benzene and substituted derivatives
Direct Parent
Diphenylacetonitriles
Alternative Parents
Diphenylmethanes / Alpha amino acid amides / Piperidinecarboxamides / Aralkylamines / Aminopiperidines / Trialkylamines / Primary carboxylic acid amides / Nitriles / Azacyclic compounds / Organopnictogen compounds
show 3 more
Substituents
Diphenylacetonitrile / Diphenylmethane / Alpha-amino acid amide / Alpha-amino acid or derivatives / Piperidinecarboxamide / 4-aminopiperidine / Aralkylamine / Piperidine / Amino acid or derivatives / Carboxamide group
show 18 more
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
Not Available

Drug created on October 20, 2016 16:35 / Updated on September 01, 2017 12:21