| Butalbital | A barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine. |
| Choline | A nutrient found in a wide variety of vitamins including pre-natal formulations. |
| Tryptophan | An amino acid commonly found as a component of total parenteral nutrition. |
| Fluvoxamine | A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. |
| Amphetamine | A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). |
| Nicotine | A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. |
| Cevimeline | A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome. |
| Lorazepam | A long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. |
| Ethchlorvynol | A sedative hypnotic agent used for the short-term management of insomnia. |
| Tramadol | A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. |
| Caffeine | A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. |
| Citalopram | A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. |
| Eletriptan | A triptan used for the treatment of migraines. |
| Enflurane | A halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery. |
| Pregabalin | An anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants. |
| Reboxetine | For the treatment of clinical depression. |
| Benzatropine | An anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. |
| Ziprasidone | An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. |
| Methysergide | An ergot alkaloid used for the prophylaxis of migraine and cluster headaches. |
| Phenytoin | An anticonvulsant drug used in the prophylaxis and control of various types of seizures. |
| Ropinirole | A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome. |
| Topiramate | An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. |
| Lidocaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Venlafaxine | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. |
| Atomoxetine | A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD). |
| Etomidate | A short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. |
| Morphine | An opioid agonist used for the relief of moderate to severe acute and chronic pain. |
| Ropivacaine | An analgesic drug used for local or regional anesthesia for surgery and short-term management of pain. |
| Bupivacaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Talbutal | For use as a sedative and hypnotic. |
| Pentobarbital | A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. |
| Valproic acid | An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. |
| Zolmitriptan | A triptan drug used for the acute treatment of migraine. |
| Acetaminophen | An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. |
| Dihydroergotamine | An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. |
| Tolcapone | A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. |
| Hydromorphone | An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. |
| Methadone | An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. |
| Olanzapine | An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. |
| Metixene | Used for the symptomatic treatment of parkinsonism. |
| Protriptyline | A tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision. |
| Trimethadione | An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. |
| Clobazam | A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. |
| Clozapine | An antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. |
| Mirtazapine | A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. |
| Meprobamate | An anxiolytic drug used for the short-term management of anxiety symptoms. |
| Trihexyphenidyl | An antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS). |
| Tacrine | For the palliative treatment of mild to moderate dementia of the Alzheimer's type. |
| Procyclidine | An antispasmodic drug used to treat parkinsonism of various types and in the treatment of extrapyramidal symptoms. |
| Sulpiride | Sulpiride is indicated for the treatment of schizophrenia. |
| Profenamine | An antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease. |
| Eszopiclone | A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. |
| Alprazolam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. |
| Loxapine | A antipsychotic used for the treatment of schizophrenia. |
| Remoxipride | Remoxipride is an atypical antipsychotic once used for the treatment of schizophrenia. |
| Pramipexole | A non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). |
| Secobarbital | A barbiturate used for the short-term treatment of insomnia. |
| Promazine | A phenothiazine used to manage schizophrenia. |
| Methylphenidate | A stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD). |
| Zolpidem | A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. |
| Prochlorperazine | A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. |
| Droperidol | A butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting. |
| Meperidine | An opioid agonist with analgesic and sedative properties used to manage severe pain. |
| Imipramine | A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. |
| Metharbital | Metharbital is used for the treatment of epilepsy. |
| Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| Methohexital | An anesthetic used to induce deep sedation. |
| Chlordiazepoxide | A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. |
| Duloxetine | A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. |
| Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
| Buspirone | An anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression. |
| Entacapone | A selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. |
| Oxycodone | An opioid used in the management of moderate to severe pain. |
| Haloperidol | An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. |
| Triflupromazine | Used mainly in the management of psychoses. Also used to control nausea and vomiting. |
| Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| Mephenytoin | A phenylhydantoin used to treat refractory partial epilepsy. |
| Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
| Amoxapine | A tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression. |
| Pyridostigmine | A cholinesterase inhibitor used to treat myasthenia gravis. |
| Adinazolam | For the treatment of anxiety and status epilepticus. |
| Lamotrigine | A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. |
| Hydroxyzine | An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria. |
| Cinnarizine | For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins. |
| Lisuride | For the management of Parkinson's Disease |
| Ethosuximide | An anticonvulsant used to treat petit mal seizures. |
| Thiopental | A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. |
| Butorphanol | An opioid agonist-antagonist used to treat moderate to severe pain. |
| Paramethadione | Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications. |
| Fluphenazine | A phenothiazine used to treat patients requiring long-term neuroleptic therapy. |
| Dexmedetomidine | An alpha-2 agonist used for sedation during various procedures. |
| Dextropropoxyphene | An opioid analgesic used to treat mild to moderate pain. |
| Pentazocine | An analgesic used to treat moderate to severe pain. |
| Trazodone | A serotonin uptake inhibitor used to treat major depressive disorder. |
| Acamprosate | A medication used to maintain alcohol abstinence in patients with alcohol dependence. |
| Galantamine | A benzazepine derivative used to treat mild to moderate dementia associated with Alzheimer's Disease. |
| Thioridazine | A phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. |
| Midazolam | A short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. |
| Flurazepam | A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. |
| Ergotamine | A alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. |
| Naltrexone | A narcotic antagonist used in opioid overdose. |
| Sufentanil | An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. |
| Apomorphine | A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. |
| Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| Trimipramine | A tricyclic antidepressant used to treat depression. |
| Risperidone | A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. |
| Riluzole | A glutamate antagonist used to treat amyotrophic lateral sclerosis. |
| Modafinil | A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. |
| Prilocaine | A local anesthetic used in dental procedures. |
| Tranylcypromine | A monoamine oxidase inhibitor used to treat major depressive disorder. |
| Isoflurane | An inhaled general anesthetic used in surgery. |
| Ethotoin | A hydantoin antiepileptic used to control tonic-clonic and complex partial seizures. |
| Oxcarbazepine | An anti-epileptic used in the treatment of partial-onset seizures. |
| Propiomazine | Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia. |
| Phenelzine | A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression. |
| Primidone | An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. |
| Halazepam | Used to relieve anxiety, nervousness, and tension associated with anxiety disorders. |
| Alfentanil | An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. |
| Minaprine | For the treatment of depression |
| Biperiden | A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. |
| Fentanyl | An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. |
| Propofol | A medication used in general anesthesia and for sedation. |
| Diazepam | A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. |
| Trifluoperazine | A phenothiazine used to treat depression, anxiety, and agitation. |
| Phensuximide | For the treatment of epilepsy. |
| Progabide | Indicated for the treatment of epilepsy. |
| Oxazepam | An intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia. |
| Donepezil | An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. |
| Nalbuphine | An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. |
| Methylphenobarbital | For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. |
| Perphenazine | A phenothiazine used to treat schizophrenia as well as nausea and vomiting. |
| Diflunisal | An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. |
| Flupentixol | A thioxanthene neuroleptic used to treat schizophrenia and depression. |
| Triazolam | A benzodiazepine used for short term treatment of insomnia. |
| Remifentanil | An opioid analgesic used in anesthesia. |
| Tiagabine | An antiepileptic used to treat partial seizures. |
| Zonisamide | A sulfonamide anticonvulsant used to treat partial seizures. |
| Anileridine | An opioid analgesic used to treat moderate to severe pain. |
| Amantadine | A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. |
| Almotriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Buprenorphine | A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. |
| Mesoridazine | A phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses. |
| Maprotiline | A tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression. |
| Salicylic acid | An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. |
| Felbamate | An anticonvulsant used to treat severe epilepsy. |
| Naratriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Rizatriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Mepivacaine | A local anesthetic used for local or regional analgesia or anesthesia. |
| Zaleplon | A sedative used for short term treatment of insomnia in adults. |
| Ramelteon | A melatonin receptor agonist used to treat insomnia. |
| Rivastigmine | A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. |
| Gabapentin | An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. |
| Frovatriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Levobupivacaine | For the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management |
| Bethanechol | A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. |
| Methoxyflurane | For use in the induction and maintenance of general anesthesia |
| Selegiline | A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. |
| Memantine | An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. |
| Acetophenazine | For the treatment of disorganized and psychotic thinking. Also used to help treat false perceptions (e.g. hallucinations or delusions.) |
| Melatonin | An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. |
| Clonazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. |
| Vigabatrin | An irreversible GABA transaminase inhibitor used as an adjunct to treat refractory complex partial seizures in patients ≥10 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. |
| Pilocarpine | A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. |
| Pimozide | An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder. |
| Sertraline | A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. |
| Methyprylon | For the treatment of insomnia. |
| Phenacemide | Used to control certain seizures in the treatment of epilepsy. |
| Ambenonium | A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. |
| Doxepin | A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. |
| Nefazodone | An antidepressant used in the treatment of depression. |
| Desipramine | A tricyclic antidepressant used in the treatment of depression. |
| Thiamylal | Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. |
| Bupropion | A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. |
| Halothane | A general inhalation anesthetic used for the induction and maintenance of general anesthesia. |
| Chloroprocaine | A local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia. |
| Moclobemide | A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. |
| Phenobarbital | A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. |
| Escitalopram | A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). |
| Pergolide | A long-acting dopamine agonist that is uncommonly used for the management of Parkinson's disease, due to the risk for cardiac valvulopathy. |
| Desflurane | A general inhalation anesthetic for inpatient and outpatient surgery in adults. |
| Zopiclone | A nonbenzodiazepine hypnotic used for the short-term management of insomnia. |
| Bromocriptine | A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. |
| Levetiracetam | A novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy. |
| Dezocine | Indicated in the treatment of moderate to severe pain. |
| Estazolam | A benzodiazepine used for the short-term management of insomnia. |
| Ketamine | A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. |
| Quetiapine | A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. |
| Levacetylmethadol | For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. |
| Pemoline | A central nervous system (CNS) stimulant that was previously used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. |
| Levodopa | A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. |
| Sevoflurane | A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures. |
| Aripiprazole | An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. |
| Chlorprothixene | For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders. |
| Clomipramine | A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. |
| Isocarboxazid | A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs. |
| Lisdexamfetamine | A central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders. |
| Paliperidone | An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders. |
| Varenicline | A partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. |
| Fosphenytoin | An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. |
| St. John's Wort | An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. |
| Amobarbital | A barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures. |
| Aprobarbital | Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment... |
| Butobarbital | For the treatment of insomnia. |
| Heptabarbital | Used mainly for sedation and hypnosis. |
| Hexobarbital | For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... |
| Rasagiline | An irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa. |
| Ginkgo biloba | Appears to be effective in: alleviating age-related memory impairment in some elderly people with mild to moderate age-related memory or cognitive impairment; improving cognitive function in healthy young to middle-aged... |
| Salsalate | A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. |
| Neostigmine | A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. |
| Methotrimeprazine | A phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder. |
| Aminophenazone | Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water. |
| Glutethimide | For the treatment of insomnia. |
| Diamorphine | An opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema. |
| Bezitramide | A narcotic analgesic once used for the treatment of severe chronic pain. |
| Fencamfamin | For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy. |
| Barbital | A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... |
| Camazepam | Camazepam has been used in placebo controlled studies for the treatment of patients suffering from anxiety and depression. |
| Dichloralphenazone | Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension... |
| Dextromoramide | An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070) |
| Flunitrazepam | For short-term treatment of severe insomnias, that are not responsive to other hypnotics. |
| Ethyl loflazepate | Not Available |
| Dihydrocodeine | An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. |
| Cloxazolam | Used primarily as an anti-anxiety agent. Typically used short term, and may be given as a single dose of up to 100mcg/kg to reduce anxiety and tension experienced prior to... |
| Bromazepam | A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. |
| Clotiazepam | For the treatment of anxiety disorders. |
| Chloral hydrate | A mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia. |
| Fludiazepam | Used for the short-term treatment of anxiety disorders. |
| Dextroamphetamine | A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. |
| Metamfetamine | A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. |
| Ketazolam | A long-acting benzodiazepine used to manage anxiety and insomnia. |
| Prazepam | For the treatment of anxiety disorders. |
| Quazepam | A long -acting benzodiazepine used to manage insomnia. |
| Cinolazepam | For the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. |
| Nitrazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. |
| Periciazine | A phenothiazine used with other medications to treat aggressiveness, impulsiveness, and hostility associated with psychiatric conditions such as schizophrenia. |
| Acepromazine | Acepromazine was first used in humans in the 1950s as an antipsychotic agent. It is now rarely used in humans. Acepromazine is frequently used in animals as a sedative and... |
| Molindone | An antipsychotic used to treat schizophrenia. |
| Pipotiazine | An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients. |
| Thioproperazine | An antipsychotic indicated for the management of acute and chronic schizophrenia, including cases that are refractory to more common neuroleptics. May also be used to treat manic syndromes. |
| Thiothixene | An antipsychotic indicated for the management of schizophrenia. |
| Zuclopenthixol | An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance. |
| Oxitriptan | For use as an antidepressant, appetite suppressant, and sleep aid. |
| Phenol | An antiseptic and disinfectant used in a variety of settings. |
| Phenacetin | Used principally as an analgesic. |
| Valpromide | Not Available |
| Aniracetam | Compound with anti-depressive properties used as a mental performance enhancer. |
| Choline alfoscerate | A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes... |
| Metamizole | Used in the past as a powerful painkiller and fever reducer. |
| Nialamide | Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine. |
| Nomifensine | Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA... |
| Zimelidine | For the treatment of depression. |
| Methaqualone | For the treatment of insomnia, and as a sedative and muscle relaxant. |
| Amineptine | For the treatment of depression. |
| Flunarizine | A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. |
| Fluspirilene | An antipsychotic agent used in the treatment of schizophrenia. |
| Tetrabenazine | A vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease. |
| Milnacipran | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. |
| Iloperidone | An atypical antipsychotic agent used for the acute treatment of schizophrenia in adults. |
| Lofexidine | A centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults. |
| Ezogabine | An antiepileptic agent used as an adjuvant treatment of partial-onset seizures. |
| Methsuximide | A succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures. |
| Rotigotine | A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. |
| Brivaracetam | An anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain. |
| Cariprazine | An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. |
| Sertindole | Used in the treatment of schizophrenia. |
| Mianserin | For the treatment of depression. |
| Pizotifen | A serotonin and tryptamine antagonist indicated for migraine prophylaxis. |
| Rufinamide | An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). |
| Tapentadol | An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. |
| Asenapine | An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia. |
| Lacosamide | An antiepileptic drug used to treat partial onset seizures in adults. |
| Nalmefene | An opioid antagonist used in conjunction with psychosocial support to help adults with alcohol dependence reduce alcohol consumption. |
| Ziconotide | An N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics. |
| Amisulpride | Investigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression. |
| Xaliproden | Investigated for use/treatment in amyotrophic lateral sclerosis (ALS) and alzheimer's disease. |
| Armodafinil | A stimulant used to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea, narcolepsy, or shift work disorder. |
| Clomethiazole | Investigated for use/treatment in strokes. |
| Propentofylline | Investigated for use/treatment in alzheimer's disease. |
| Etilevodopa | Investigated for use/treatment in parkinson's disease. |
| Agomelatine | Agomelatine is indicated to treat major depressive episodes in adults. |
| Flupirtine | Investigated for use/treatment in fibromyalgia. |
| Dalfampridine | A potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). |
| Vilazodone | An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. |
| Laquinimod | Investigated for use/treatment in multiple sclerosis. |
| Nitrous oxide | An inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure. |
| Betahistine | An antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease. |
| Desvenlafaxine | An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. |
| Dexmethylphenidate | A norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies. |
| Ketobemidone | For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures. |
| Triclofos | Not Annotated |
| Capsaicin | A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. |
| Mebutamate | Mebutamate is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects comparable to those of other barbiturates but is only around 1/3rd the potency of secobarbital as a... |
| Sulthiame | Not Available |
| Salicylamide | Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... |
| Tofisopam | For the treatment of anxiety and alcohol withdrawal. |
| Lurasidone | An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder. |
| Acetylcarnitine | Acetylcarnitine is not approved for any indication in the United states and Canada, but it is approved and indicated in Italy for cerebrovascular disorders, mental function disorders, peripheral nerve disorders,... |
| Perampanel | A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. |
| Adrafinil | Used to relieve excessive sleepiness and inattention in elderly patients. |
| Dimetotiazine | Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions. |
| Floctafenine | An anti-inflammatory analgesic used to manage mild to moderate acute pain. |
| Etifoxine | Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing. It does not bind to... |
| Etidocaine | Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... |
| Dimetacrine | Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in... |
| Dexetimide | A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. |
| Cyamemazine | Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. Cyamemazine actually behaves like an... |
| Barbexaclone | Created for the treatment for epilepsy, with the intent of creating an antiepileptic with less sedative properties than phenobarbital. |
| Articaine | A local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. |
| Beclamide | Has been used in the management of epilepsy and epilepsy related behavioural disorders. It was used for generalised tonic-clonic seizures, and was not effective for absence seizures.
More recently focus... |
| Captodiame | Captodiame is indicated for the treatment of anxiety. |
| Butriptyline | Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline. |
| Brotizolam | Brotizolam is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia. |
| Benzoctamine | Benzoctamine is a drug with two main uses. It can be used as a sedative which does not depress the respiratory system, but rather stimulates it. It can also be... |
| Vortioxetine | An atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). |
| Tasimelteon | A melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder. |
| Sodium oxybate | A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. |
| Idebenone | An analogue of ubiquinone used for the treatment of visual impairment in adolescent and adult patients with Leber’s Hereditary Optic Neuropathy (LHON). |
| Calcium carbimide | Calcium carbimide has not been approved by the FDA but the intended indication is for the treatment of alcoholism. This medication was marketed in Canada, United Kingdom and Europe under... |
| Paraldehyde | A central nervous system depressant previously used to control convulsions due to various clinical causes, including tetanus, status epilepticus, and convulsive drugs. |
| Stiripentol | An anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome. |
| Brexpiprazole | A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia. |
| Etizolam | Indicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia. |
| Dosulepin | Indicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required. |
| Viloxazine | Indicated for the treatment of clinical depression. |
| Etoperidone | Etoperidone has been studied for the treatment of depression , tremors in Parkinson, extrapyramidal symptoms and male impotence . It is not certain if it was ever approved and marketed... |
| Piracetam | Indicated in adult patients suffering from myoclonus of cortical origin, irrespective of aetiology, and should be used in combination with other anti-myoclonic therapies . |
| Melperone | For the treatment of schizophrenia, sleep, disorders, agitation and mentally confused states [L1317, L1319, L1322]. |
| Zotepine | Zotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes... |
| Toloxatone | For the treatment of major depressive disorder. |
| Iproclozide | For the treatment of depression. |
| Pipamperone | Treatment of chronic psychoses and states of aggressiveness of various origins . |
| Propacetamol | Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. |
| Tianeptine | Used primarily in the treatment of major depressive disorder and anxiety . It is currently being studied for fibromyalgia pain treatment . |
| Alfaxalone | Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use... |
| Chloroform | Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on... |
| Pipradrol | A central nervous stimulant ingredient in a product used to treat functional fatigue. |
| Amifampridine | A voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. |
| Pitolisant | An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults. |
| Tafamidis | A medication used to treat transthyretin-mediated amyloidosis. |
| Esketamine | A NMDA receptor antagonist used for treatment-resistant depression. |
| Vinpocetine | Vinpocetine has been investigated for the treatment of Epilepsy. |
| Gepirone | Gepirone has been used in trials studying the treatment of Cocaine-Related Disorders. |
| Nefopam | Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation. |
| Carisbamate | Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. |
| Bromperidol | Bromperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others. |
| Piribedil | Piribedil has been investigated in Parkinson's Disease. |
| Piritramide | Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting. |
| Perazine | Perazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others. |
| Benperidol | Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others. |
| Opipramol | Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders. |
| Pivagabine | Pivagabine has been used in trials studying the treatment of Stress and Anxiety. |
| Prothipendyl | Prothipendyl has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders. |
| Tiapride | Tiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. |
| Tirilazad | Tirilazad has been used in trials studying the treatment of Spinal Cord Injury. |
| Pyritinol | Pyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders. |
| Valnoctamide | Valnoctamide has been used in trials studying the treatment of Mania and Schizoaffective Disorder, Manic Type. |
| Valerian | A plant used in some non-prescription natural health products. |
| Butaperazine | Butaperazine was approved in 1967 , and possibly discontinued in the 1980s . |
| Medifoxamine | Medifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, and Morrocco in the 1990s but was later withdrawn from the market due to it causing cases... |
| Apronalide | Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura . |
| Dibenzepin | Dibenzepin is approved for use in Europe. |
| Acetylleucine | Used for treating vestibular-related imbalance and vertigo. |
| Enibomal | Not Annotated |
| Alaproclate | Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity... |
| Propanidid | An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918) |
| Quinupramine | Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant . |
| Pramiracetam | Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug... |
| Tropatepine | Tropatepine has been used in France for its antiparkinsons activities . |
| Proxibarbal | Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing... |
| Clothiapine | Clothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients. |
| Ethyl chloride | Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in... |
| Sultopride | Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics . |
| Bucetin | Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication... |
| Rimazolium | Rimazolium is an experimental analgesic drug . |
| Melevodopa | Not Annotated |
| Trichloroethylene | Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of... |
| Butanilicaine | Not Annotated |
| Pyrithyldione | Not Annotated |
| Pinazepam | Not Annotated |
| Fenozolone | Not Annotated |
| Deanol | Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. Deanol has been used in the treatment... |
| Viminol | Not Annotated |
| Pheneturide | Not Annotated |
| Bromisoval | Not Annotated |
| Vinbarbital | Not Annotated |
| Chlorproethazine | Not Annotated |
| Melitracen | Not Annotated |
| Dihydroergocryptine | Not Annotated |
| Neocitrullamon | Not Annotated |
| Acetylglycinamide chloral hydrate | Not Annotated |
| Oxypertine | Not Annotated |
| Lofepramine | Not Annotated |
| Pirisudanol | Not Annotated |
| Phenglutarimide | Not Annotated |
| Medazepam | Not Annotated |
| Prolintane | Not Annotated |
| Mazaticol | Not Annotated |
| Xenon | Not Annotated |
| Nicomorphine | Not Annotated |
| Phenibut | Not Annotated |
| Oxaflozane | Not Annotated |
| Oxetorone | Not Annotated |
| Etybenzatropine | Not Annotated |
| Meptazinol | Not Annotated |
| Iprindole | Not Annotated |
| Budipine | Not Annotated |
| Levomethadone | Not Annotated |
| Mebicar | Not Annotated |
| Veralipride | Not Annotated |
| Propyphenazone | Not Annotated |
| Gedocarnil | Not Annotated |
| Guacetisal | Not Annotated |
| Iprazochrome | Not Annotated |
| Ethenzamide | Not Annotated |
| Nizofenone | Not Annotated |
| Bifemelane | Not Annotated |
| Trifluperidol | Not Annotated |
| Moperone | Not Annotated |
| Thiopropazate | Not Annotated |
| Emylcamate | Not Annotated |
| Allobarbital | Not Annotated |
| Metabutethamine | Not Annotated |
| Diethyl ether | Not Annotated |
| Oxiracetam | Not Annotated |
| Phenoperidine | Not Annotated |
| Phenazocine | Not Annotated |
| Flumedroxone | Not Annotated |
| Carbaspirin calcium | Not Annotated |
| Bornaprine | Not Annotated |
| Fabomotizole | Not Annotated |
| Etanautine | Not Annotated |
| Loprazolam | Loprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent... |
| Benorilate | Not Annotated |
| Hexapropymate | Not Annotated |
| Fluanisone | Not Annotated |
| Ipidacrine | Not Annotated |
| Morpholine | Not Annotated |
| Mosapramine | Not Annotated |
| Niaprazine | Niaprazine is a selective brain catecholamine depletor. |
| Vinyl ether | Not Annotated |
| Distigmine | Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase... |
| Methylpentynol | Not Annotated |
| Cyclobarbital | Not Annotated |
| Mephenoxalone | Not Annotated |
| Meclofenoxate | Not Annotated |
| Vinylbital | Not Annotated |
| Imipramine oxide | Not Annotated |
| Dixyrazine | Not Annotated |
| Tilidine | Not Annotated |
| Fipexide | Not Annotated |
| Penfluridol | Not Annotated |
| Ethadione | Not Annotated |
| Reposal | Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. |
| Linopirdine | Not Annotated |
| Carbromal | Not Annotated |
| Doxefazepam | Not Annotated |
| Dipyrocetyl | Not Annotated |
| Clopenthixol | Clopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. |
| Imidazole salicylate | Not Annotated |
| Lormetazepam | For the treatment of short-term insomnia |
| Choline salicylate | The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... |
| Nordazepam | An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. |
| Cabergoline | A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. |
| Codeine | An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. |
| Carbamoylcholine | A direct acting miotic agent administered ophthalmically to decrease intraocular pressure in glaucoma or after eye surgery, and to induce miosis during surgery. |
| Cinchocaine | An anesthetic used for local or regional anesthesia. |
| Clonidine | An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. |
| Dyclonine | An topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters. |
| Sumatriptan | A serotonin receptor agonist used to treat migraines and cluster headaches. |
| Procaine | A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. |
| Scopolamine | An anticholinergic used to treat excessive salivation, colicky abdominal pain, bradycardia, diverticulitis, IBS, and motion sickness. |
| Disulfiram | A carbamate derivative used to treat alcohol addiction. |
| Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| Benzocaine | A topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations. |
| Orphenadrine | A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. |
| Antipyrine | An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. |
| Fenethylline | Not Available |
| Tetracaine | A local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. |
| Opium | A medication used to treat moderate to severe pain. |
| Nifenazone | Not Annotated |
| Emepronium | Not Annotated |
| Aloxiprin | Not Annotated |
| Eslicarbazepine | Adjunctive Therapy for Adults with Partial-Onset Seizures |
| Eslicarbazepine acetate | An anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy. |
| Citicoline | Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnostic of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar... |
| Chlorhexadol | Chlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate. |
| Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. |
| Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
| Pimavanserin | A second generation atypical antipsychotic used for the treatment of hallucinations and delusions caused by Parkinson's Disease. |
| Safinamide | A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. |
| Cytisine | Indicated for use in smoking cessation. |
| Suvorexant | A orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. |
| Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
| Dexketoprofen | For short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache . |
| Opicapone | A catechol-O-methyltransferase inhibitor used to treat Parkinson's disease in patients currently receiving levodopa and a dopa decarboxylase inhibitor. |
| Valbenazine | A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia. |
| Edaravone | A free radical scavenger used to delay the progression of ALS. |
| Erenumab | A calcitonin-gene related peptide antagonist used to prevent migraines. |
| Galcanezumab | A calcitonin-gene related peptide antagonist used to prevent migraines and treat cluster headaches. |
| Patisiran | A transthyretin-directed small interfering RNA used to treat polyneuropathy of hereditary transthyretin-mediated amyloidosis. |
| Bentazepam | Not Annotated |
| Lithium carbonate | A medication used to treat manic episodes of bipolar disorder. |
| Iproniazid | For the treatment of depression (originally intended to treat tuberculosis). |