Sensory System Agents

Name
Sensory System Agents
Accession Number
DBCAT000042
Description

Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367)

Drugs
DrugDrug Description
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
MorphineAn opioid agonist used for the relief of moderate to severe acute and chronic pain.
RopivacaineAn analgesic drug used for local or regional anesthesia for surgery and short-term management of pain.
BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
HydromorphoneAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
PimecrolimusA topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
CarbamoylcholineA direct acting miotic agent administered ophthalmically to decrease intraocular pressure in glaucoma or after eye surgery, and to induce miosis during surgery.
MeperidineAn opioid agonist with analgesic and sedative properties used to manage severe pain.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
DuloxetineA serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
OxycodoneAn opioid used in the management of moderate to severe pain.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
LevallorphanFor the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids.
CinchocaineAn anesthetic used for local or regional anesthesia.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
ButorphanolAn opioid agonist-antagonist used to treat moderate to severe pain.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
AdenosineA medication used in myocardial perfusion scintigraphy.
DyclonineAn topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters.
DextropropoxypheneAn opioid analgesic used to treat mild to moderate pain.
PentazocineAn analgesic used to treat moderate to severe pain.
Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
ErgotamineA alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
NaltrexoneA narcotic antagonist used in opioid overdose.
SufentanilAn opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
ProcaineA local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
PrilocaineA local anesthetic used in dental procedures.
OlopatadineA histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
SulfasalazineAn anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis.
AlfentanilAn opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
ProparacaineA topical anesthetic used for ophthalmic practice.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
FentanylAn opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
CarprofenFor use as a pain reliever in the treatment of joint pain and post-surgical pain.
NalbuphineAn opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery.
LevorphanolAn opioid analgesic used to treat moderate to severe pain.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
OxybuprocaineA local anesthetic used in ophthalmology.
RemifentanilAn opioid analgesic used in anesthesia.
CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
HydrocodoneAn opioid agonist used as an analgesic and antitussive agent.
MepivacaineA local anesthetic used for local or regional analgesia or anesthesia.
BromfenacAn NSAID used to treat postoperative pain and inflammation of the eye.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
BenzocaineA topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.
NaloxoneAn opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
OxymorphoneAn opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
DezocineIndicated in the treatment of moderate to severe pain.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
Methadyl acetateUsed mainly in the treatment of narcotic dependence.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
DihydroetorphineNot Available
DiamorphineAn opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema.
BezitramideA narcotic analgesic once used for the treatment of severe chronic pain.
EthylmorphineEthylmorphine is an analgesic used for pain relief.
EtorphineEtorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals.
EcgonineNot Available
DextromoramideAn opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
CarfentanilCarfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals.
DrotebanolNot Available
DiprenorphineDiprenorphine is indicated to reverse the effects of powerful opioids including etorphine and carfentanil, often used for tranquilizing large animals. This drug is not approved for use in humans.
DihydrocodeineAn opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
AlphacetylmethadolA narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem]
DihydromorphineDihydromorphine is an opioid analgesic used for moderate to severe pain relief.
OhmefentanylOhmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl...
3-Methylfentanyl3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be...
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
CastanospermineNot Available
7-NitroindazoleNot Available
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
PhenacetinUsed principally as an analgesic.
Niflumic acidUsed in the treatment of rheumatoid arthritis.
MethylecgonineNot Available
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
BenoxaprofenThe use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
MetamizoleUsed in the past as a powerful painkiller and fever reducer.
ZomepiracZomepirac was indicated for the management of mild to severe pain.
VapreotideFor the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
PTC299Investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
Samarium (153Sm) lexidronamA chelated complex of samarium isotope and EDTMP that concentrates in areas with high bone turnover such as sites of metastases to relieve pain associated with osteoblastic metastatic bone lesions.
CanertinibInvestigated for use/treatment in breast cancer and lung cancer.
AndrographolideInvestigated for use/treatment in ulcerative colitis.
PizotifenA serotonin and tryptamine antagonist indicated for migraine prophylaxis.
IcatibantA bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE).
NalmefeneAn opioid antagonist used in conjunction with psychosocial support to help adults with alcohol dependence reduce alcohol consumption.
ExisulindInvestigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
ZiconotideAn N-type calcium channel antagonist used to manage patients with severe chronic pain who cannot tolerate, or who have not responded adequately to other treatments such as intrathecal morphine and systemic analgesics.
GaboxadolInvestigated for use/treatment in sleep disorders and insomnia.
FlupirtineInvestigated for use/treatment in fibromyalgia.
Nitrous oxideAn inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure.
LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
ZaltoprofenA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
SeratrodastSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
DrotaverineUsed in the treatment of functional bowel disorders and alleviating pain in renal colic.
Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
MethylnaltrexoneA μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
AzapropazoneNot Available
FelbinacNot Available
TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
EpibatidineNot Available
Ferulic acidNot Available
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
SalicylamideSalicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....
DPDPEA heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond.
TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
KebuzoneKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
IsoxicamIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EtofenamateEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
EtidocaineEtidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage...
EpirizoleEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
ArticaineA local anesthetic used for inducing local, infiltrative, or conductive anesthesia in both simple and complex dental procedures.
NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
LofentanilLofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more...
PholcodinePholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."...
LoxoprofenLoxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders. In addition to its effects on pain, it is an antipyretic and anti-inflammatory...
DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
ClonixinIndicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and...
PramocaineA local anesthetic and antipruritic agent found in various topical preparations.
OpiumA medication used to treat moderate to severe pain.
ButambenAnesthesia of mucus membranes other than the eyes.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
MedetomidineMedetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist....
TepoxalinTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...
XylazineXylazine is a clonidine analog which acts as an agonist at α2 adrenoceptors. Veterinarians also use xylazine as an emetic, especially in cats.
NalorphineUsed to reverse opioid overdose.
ButacaineNot Annotated
FlunixinFlunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form....
DetomidineUsed as a large animal sedative, primarily in horses.
NormethadoneAn opioid antitussive used to treat a cough associated with inflamed mucosa.
CurcuminNo approved therapeutic indications.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
SemapimodSemapimod has been used in trials studying the treatment of Crohn Disease.
BucillamineBucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
NefopamNefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
LisofyllineLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
PiritramidePiritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
SamidorphanSamidorphan has been used in trials studying the treatment of Schizophrenia, Alcohol Dependence, and Binge Eating Disorder.
IndobufenIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
ApocyninAcetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
SpiradolineSpiradoline has been investigated for the basic science of Bipolar Depression.
HigenamineHigenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).
TinoridineTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
ParthenolideParthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis.
SerrapeptaseSerrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections. Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet)...
AlphaprodineNot Annotated
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
FentiazacNot Annotated
TribenosideAnti-inflammatory agent used in edema of extremities, varicose veins & phlebitis.
SuxibuzoneNot Annotated
Ethyl chlorideEthyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in...
BumadizoneBumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
AlminoprofenAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
FlunoxaprofenNot Annotated
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
FeprazoneNot Annotated
DifenpiramideNot Annotated
NifenazoneNot Annotated
LonazolacNot Annotated
MeptazinolNot Annotated
TenidapNot Annotated
BendazacPrior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the...
PranoprofenNot Annotated
MebicarNot Annotated
PropyphenazoneNot Annotated
ProglumetacinNot Annotated
GuacetisalNot Annotated
BevoniumNot Annotated
EthenzamideNot Annotated
PhenoperidineNot Annotated
PhenazocineNot Annotated
Carbaspirin calciumNot Annotated
MofebutazoneNot Annotated
ProquazoneNot Annotated
BenorilateNot Annotated
QuinisocaineNot Annotated
PirprofenNot Annotated
AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation...
DixyrazineNot Annotated
TilidineNot Annotated
Imidazole salicylateNot Annotated
WIN 55212-2WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
Thiosalicylic acidNot Annotated
PalmidrolA cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food...
SC-236SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
TaxifolinNot Available
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
EbselenEbselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
Human interleukin-2Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Flurbiprofen axetilFlurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).
Carfentanil, C-11Carfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain).
DesomorphineNot Available
LicofeloneFor the management of osteoarthritis.
MilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
EcallantideA kallikrein inhibitor used to prevent and treat acute attacks caused by Hereditary Angioedema (HAE).
RI 624Investigated for use/treatment in pain (acute or chronic).
TapentadolAn opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate.
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
FasinumabFasinumab has been used in trials studying the basic science and treatment of Sciatica, Back Pain, Low Back Pain, Osteoarthritis, Hip, and Abdominal Pain Upper, among others.
TanezumabTanezumab has been investigated for the treatment of Osteoarthritis, Knee and Neuralgia, Postherpetic.
LY-2456302Ly2456302 has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.
NicomorphineNot Annotated
NabiximolsIn Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
ErenumabA calcitonin-gene related peptide antagonist used to prevent migraines.
GalcanezumabA calcitonin-gene related peptide antagonist used to prevent migraines and treat cluster headaches.
DextromethadoneDextromethadone is under investigation in clinical trial NCT00588640 (Study of D-Methadone in Patients With Chronic Pain).
Ursolic acidNot Annotated
KelatorphanNot Available
Drugs & Drug Targets
DrugTargetType
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
TramadolMu-type opioid receptortarget
TramadolSodium-dependent noradrenaline transportertarget
Tramadol5-hydroxytryptamine receptor 2Ctarget
TramadolKappa-type opioid receptortarget
TramadolSodium-dependent serotonin transportertarget
TramadolCytochrome P450 2D6enzyme
TramadolDelta-type opioid receptortarget
TramadolCytochrome P450 3A4enzyme
TramadolCytochrome P450 2B6enzyme
TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
TramadolMuscarinic acetylcholine receptor M3target
TramadolMuscarinic acetylcholine receptor M1target
TramadolUDP-glucuronosyltransferase 1-1enzyme
TramadolNeurokinin 1 receptortarget
TramadolSodium channel protein type 2 subunit alphatarget
TramadolTransient receptor potential cation channel subfamily V member 1target
TramadolNMDA receptortarget
TramadolAdenosine receptor A1target
TramadolAlpha-2 adrenergic receptorstarget
PregabalinExcitatory amino acid transporter 3transporter
PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
PregabalinLarge neutral amino acids transporter small subunit 1transporter
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 1A2enzyme
LidocaineCytochrome P450 2D6enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A7enzyme
LidocaineSolute carrier family 22 member 5transporter
LidocaineP-glycoprotein 1transporter
LidocaineCytochrome P450 2A6enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineAlpha-1-acid glycoprotein 2target
MorphineMu-type opioid receptortarget
MorphineDelta-type opioid receptortarget
MorphineKappa-type opioid receptortarget
MorphineP-glycoprotein 1transporter
MorphineCytochrome P450 2C8enzyme
MorphineCytochrome P450 3A4enzyme
MorphineUDP-glucuronosyltransferase 2B7enzyme
MorphineUDP-glucuronosyltransferase 1-1enzyme
MorphineUDP-glucuronosyltransferase 1-8enzyme
MorphineUDP-glucuronosyltransferase 2B15enzyme
MorphineUDP-glucuronosyltransferase 2B4enzyme
MorphineUDP-glucuronosyltransferase 1-3enzyme
MorphineLymphocyte antigen 96target
MorphineSerum albumincarrier
RopivacaineSodium channel protein type 10 subunit alphatarget
RopivacaineCytochrome P450 1A2enzyme
RopivacaineCytochrome P450 2B6enzyme
RopivacaineCytochrome P450 3A4enzyme
BupivacaineSodium channel protein type 10 subunit alphatarget
BupivacaineProstaglandin E2 receptor EP1 subtypetarget
BupivacaineCytochrome P450 3A4enzyme
BupivacaineCytochrome P450 2C19enzyme
BupivacaineCytochrome P450 2D6enzyme
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenP-glycoprotein 1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3/1A4enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenSerum albumincarrier
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
CodeineMu-type opioid receptortarget
CodeineDelta-type opioid receptortarget
CodeineKappa-type opioid receptortarget
CodeineCytochrome P450 2D6enzyme
CodeineCytochrome P450 3A4enzyme
CodeineSolute carrier family 22 member 1transporter
CodeineUDP-glucuronosyltransferase 2B7enzyme
CodeineUDP-glucuronosyltransferase 2B4enzyme
Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DihydroergotamineCytochrome P450 3A4enzyme
DihydroergotamineAlpha-2A adrenergic receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DihydroergotamineP-glycoprotein 1transporter
AmitriptylineSodium-dependent serotonin transportertarget
AmitriptylineSodium-dependent noradrenaline transportertarget
AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
AmitriptylineAlpha-2A adrenergic receptortarget
AmitriptylineCytochrome P450 1A2enzyme
AmitriptylineCytochrome P450 2C19enzyme
AmitriptylineCytochrome P450 2D6enzyme
AmitriptylineSerum albumincarrier
AmitriptylineAlpha-1-acid glycoprotein 1carrier
AmitriptylineHistamine H1 receptortarget
Amitriptyline5-hydroxytryptamine receptor 2Atarget
Amitriptyline5-hydroxytryptamine receptor 1Atarget
AmitriptylineAlpha-1A adrenergic receptortarget
AmitriptylineCytochrome P450 3A4enzyme
AmitriptylineCytochrome P450 3A5enzyme
AmitriptylinePotassium voltage-gated channel subfamily A member 1target
AmitriptylineAlpha-1D adrenergic receptortarget
AmitriptylineDelta-type opioid receptortarget
AmitriptylineKappa-type opioid receptortarget
AmitriptylineHigh affinity nerve growth factor receptortarget
AmitriptylineBDNF/NT-3 growth factors receptortarget
AmitriptylineCytochrome P450 2C9enzyme
AmitriptylineCytochrome P450 2B6enzyme
AmitriptylineCytochrome P450 2C8enzyme
AmitriptylineHistamine H2 receptortarget
AmitriptylineHistamine H4 receptortarget
AmitriptylineSigma non-opioid intracellular receptor 1target
Amitriptyline5-hydroxytryptamine receptor 2Ctarget
AmitriptylineAlpha-1B adrenergic receptortarget
Amitriptyline5-hydroxytryptamine receptor 7target
Amitriptyline5-hydroxytryptamine receptor 1Dtarget
AmitriptylineMu-type opioid receptortarget
Amitriptyline5-hydroxytryptamine receptor 1Btarget
Amitriptyline5-hydroxytryptamine receptor 6target
AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
Amitriptyline5-hydroxytryptamine receptor 1Ctarget
AmitriptylineMuscarinic acetylcholine receptortarget
AmitriptylineHERG human cardiac K+ channeltarget
AmitriptylineP-glycoprotein 1transporter
AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
HydromorphoneMu-type opioid receptortarget
HydromorphoneDelta-type opioid receptortarget
HydromorphoneKappa-type opioid receptortarget
HydromorphoneCytochrome P450 2C9enzyme
HydromorphoneUDP-glucuronosyltransferase 1-3enzyme
HydromorphoneUDP-glucuronosyltransferase 2B7enzyme
HydromorphoneSerum albumincarrier
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
MethadoneNMDA receptortarget
MethadoneMu-type opioid receptortarget
MethadoneCytochrome P450 2B6enzyme
MethadoneCytochrome P450 3A4enzyme
MethadoneCytochrome P450 2C19enzyme
MethadoneDelta-type opioid receptortarget
MethadoneCytochrome P450 3A7enzyme
MethadoneCytochrome P450 2D6enzyme
MethadoneP-glycoprotein 1transporter
MethadoneCytochrome P450 2C8enzyme
MethadoneCytochrome P450 19A1enzyme
MethadoneCytochrome P450 1A2enzyme
MethadoneCytochrome P450 2C18enzyme
MethadoneCytochrome P450 2C9enzyme
Methadone5-hydroxytryptamine receptor 3Atarget
MethadoneAlpha-1-acid glycoprotein 1carrier
MethadoneSerum albumincarrier
MethadoneNeuronal acetylcholine receptor subunit alpha-7target
MethadoneNeuronal acetylcholine receptor subunit alpha-3target
MethadoneNeuronal acetylcholine receptor subunit alpha-4target
MethadoneNeuronal acetylcholine receptor subunit beta-2target
PimecrolimusPeptidyl-prolyl cis-trans isomerase FKBP1Atarget
PimecrolimusSerine/threonine-protein kinase mTORtarget
PimecrolimusCytochrome P450 3A4enzyme
CarbamoylcholineMuscarinic acetylcholine receptor M1target
CarbamoylcholineMuscarinic acetylcholine receptor M2target
CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
CarbamoylcholineCytosolic phospholipase A2enzyme
CarbamoylcholineAcetylcholinesterasetarget
CarbamoylcholineMuscarinic acetylcholine receptor M3target
CarbamoylcholineMuscarinic acetylcholine receptor M4target
MeperidineKappa-type opioid receptortarget
MeperidineCytochrome P450 2D6enzyme
MeperidineCytochrome P450 2B6enzyme
MeperidineGlutamate receptor ionotropic, NMDA 1target
MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
MeperidineCytochrome P450 2C19enzyme
MeperidineCytochrome P450 3A4enzyme
MeperidineSerum albumincarrier
MeperidineAlpha-1-acid glycoprotein 1carrier
MeperidineMuscarinic acetylcholine receptortarget
MeperidineMu-type opioid receptortarget
MeperidineSodium-dependent dopamine transportertarget
MeperidineSodium-dependent noradrenaline transportertarget
MeperidineSodium-dependent serotonin transportertarget
MeperidineLiver carboxylesterase 1target
MeperidineCytochrome P450 1A2enzyme
MeperidineP-glycoprotein 1transporter
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
DronabinolCannabinoid receptor 1target
DronabinolCytochrome P450 3A4enzyme
DronabinolCytochrome P450 2C9enzyme
DronabinolCannabinoid receptor 2target
DronabinolP-glycoprotein 1transporter
DronabinolATP-binding cassette sub-family G member 2transporter
DronabinolProstaglandin G/H synthase 1enzyme
DuloxetineSodium-dependent serotonin transportertarget
DuloxetineSodium-dependent dopamine transportertarget
DuloxetineSodium-dependent noradrenaline transportertarget
DuloxetineCytochrome P450 1A2enzyme
DuloxetineCytochrome P450 2D6enzyme
DuloxetineCytochrome P450 2C9enzyme
DuloxetineSerum albumincarrier
Duloxetinealpha1-acid glycoproteincarrier
DuloxetineP-glycoprotein 1transporter
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
OxycodoneMu-type opioid receptortarget
OxycodoneKappa-type opioid receptortarget
OxycodoneDelta-type opioid receptortarget
OxycodoneCytochrome P450 2D6enzyme
OxycodoneCytochrome P450 3A4enzyme
OxycodoneCytochrome P450 3A5enzyme
OxycodoneSerum albumincarrier
Oxycodonealpha1-acid glycoproteincarrier
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinSerum albumincarrier
LevallorphanMu-type opioid receptortarget
CinchocaineSodium channel protein type 5 subunit alphatarget
CinchocaineSodium channel protein type 10 subunit alphatarget
CinchocaineCalmodulintarget
CinchocaineCholinesteraseenzyme
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineP-glycoprotein 1transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
SulindacProstaglandin G/H synthase 2target
SulindacAldose reductasetarget
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacSerum albumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
ChloroquineTumor necrosis factortarget
ChloroquineToll-like receptor 9target
ChloroquineGlutathione S-transferase A2target
ChloroquineCytochrome P450 2D6enzyme
ChloroquineCytochrome P450 3A4enzyme
ChloroquineCytochrome P450 1A1enzyme
ChloroquineCytochrome P450 2C8enzyme
ChloroquineCytochrome P450 3A5enzyme
ChloroquineGlutathione S-transferasetarget
ChloroquineP-glycoprotein 1transporter
ChloroquineSerum albumincarrier
Chloroquinealpha1-acid glycoproteincarrier
ChloroquineHigh mobility group protein B1target
ChloroquineGlutathione S-transferase Mu 1target
ChloroquineAngiotensin-converting enzyme 2target
ButorphanolKappa-type opioid receptortarget
ButorphanolMu-type opioid receptortarget
ButorphanolDelta-type opioid receptortarget
DexmedetomidineAlpha-2A adrenergic receptortarget
DexmedetomidineCytochrome P450 2E1enzyme
DexmedetomidineCytochrome P450 1A2enzyme
DexmedetomidineCytochrome P450 1A1enzyme
DexmedetomidineCytochrome P450 2D6enzyme
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
DyclonineSodium channel protein type 10 subunit alphatarget
DextropropoxypheneMu-type opioid receptortarget
DextropropoxypheneDelta-type opioid receptortarget
DextropropoxypheneKappa-type opioid receptortarget
DextropropoxypheneCytochrome P450 2D6enzyme
DextropropoxypheneCytochrome P450 3A4enzyme
DextropropoxypheneLiver carboxylesterase 1target
PentazocineMu-type opioid receptortarget
PentazocineKappa-type opioid receptortarget
PentazocineSigma non-opioid intracellular receptor 1target
PentazocineP-glycoprotein 1transporter
Magnesium sulfateVoltage-dependent L-type calcium channeltarget
ErgotamineAlpha-1A adrenergic receptortarget
Ergotamine5-hydroxytryptamine receptor 1Dtarget
Ergotamine5-hydroxytryptamine receptor 1Btarget
Ergotamine5-hydroxytryptamine receptor 2Atarget
ErgotamineAlpha-2A adrenergic receptortarget
ErgotamineDopamine D2 receptortarget
ErgotamineCytochrome P450 3A4enzyme
ErgotamineAlpha-1B adrenergic receptortarget
ErgotamineAlpha-1D adrenergic receptortarget
ErgotamineP-glycoprotein 1transporter
ErgotamineD(1) dopamine receptortarget
Ergotamine5-hydroxytryptamine receptor 1Atarget
Ergotamine5-hydroxytryptamine receptor 1Ftarget
Ergotamine5-hydroxytryptamine receptor 2Ctarget
Ergotamine5-hydroxytryptamine receptor 2Btarget
ErgotamineAlpha-2C adrenergic receptortarget
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
NaltrexoneMu-type opioid receptortarget
NaltrexoneKappa-type opioid receptortarget
NaltrexoneDelta-type opioid receptortarget
NaltrexoneHCG20471, isoform CRA_ctarget
NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
SufentanilMu-type opioid receptortarget
SufentanilDelta-type opioid receptortarget
SufentanilKappa-type opioid receptortarget
SufentanilCytochrome P450 3A4enzyme
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenSerum albumincarrier
FlurbiprofenMultidrug resistance-associated protein 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
ProcaineSodium channel protein type 10 subunit alphatarget
ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
Procaine5-hydroxytryptamine receptor 3Atarget
ProcaineSodium-dependent dopamine transportertarget
ProcaineNeuronal acetylcholine receptor subunit alpha-2target
ProcaineCholinesteraseenzyme
ProcaineDNA (cytosine-5)-methyltransferase 1target
ProcaineCalcium-activated potassium channeltarget
ProcaineCytosolic phospholipase A2target
Procaine60 kDa lysophospholipasetarget
ProcaineMonoamine oxidasetarget
ProcaineSodium-dependent dopamine transportertransporter
ProcaineSodium-dependent noradrenaline transportertransporter
ProcaineSodium-dependent serotonin transportertransporter
ProcaineDNA (cytosine-5)-methyltransferase 3Atarget
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1-9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacSerum albumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1-3enzyme
EtodolacUDP-glucuronosyltransferase 1-10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
PrilocaineSodium channel protein type 5 subunit alphatarget
OlopatadineHistamine H1 receptortarget
OlopatadineProtein S100-A1target
OlopatadineProtein S100-A12target
OlopatadineProtein S100-Btarget
OlopatadineProtein S100-A13target
OlopatadineProtein S100-A2target
OlopatadineCytochrome P450 3A4enzyme
OlopatadineSerum albumincarrier
OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlopatadineP-glycoprotein 1transporter
OlopatadineHistamine H2 receptortarget
OlopatadineHistamine H3 receptortarget
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
SulfasalazineAcetyl-CoA acetyltransferase, mitochondrialtarget
SulfasalazineCystine/glutamate transportertarget
SulfasalazineATP-binding cassette sub-family G member 2transporter
SulfasalazineCanalicular multispecific organic anion transporter 1transporter
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
SulfasalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
SulfasalazineProstaglandin G/H synthase 2target
SulfasalazinePeroxisome proliferator-activated receptor gammatarget
SulfasalazineProstaglandin G/H synthase 1target
SulfasalazineArachidonate 5-lipoxygenasetarget
SulfasalazineProton-coupled folate transportertransporter
SulfasalazineThromboxane-A synthasetarget
SulfasalazinePhospholipase A2target
SulfasalazineSolute carrier organic anion transporter family member 1B1transporter
SulfasalazineSolute carrier organic anion transporter family member 1B3transporter
SulfasalazineSolute carrier organic anion transporter family member 2B1transporter
AlfentanilMu-type opioid receptortarget
AlfentanilCytochrome P450 3A4enzyme
AlfentanilCytochrome P450 3A5enzyme
AlfentanilAlpha-1-acid glycoprotein 1carrier
AlfentanilSerum albumincarrier
AlfentanilCytochrome P450 3A7enzyme
AlfentanilP-glycoprotein 1transporter
ProparacaineSodium channel protein type 10 subunit alphatarget
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneSolute carrier family 22 member 8transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
FentanylMu-type opioid receptortarget
FentanylDelta-type opioid receptortarget
FentanylCytochrome P450 3A4enzyme
FentanylCytochrome P450 3A7enzyme
FentanylP-glycoprotein 1transporter
FentanylKappa-type opioid receptortarget
FentanylP-glycoprotein 1target
FentanylSerum albumincarrier
Fentanylalpha1-acid glycoproteincarrier
MeloxicamProstaglandin G/H synthase 2target
MeloxicamCytochrome P450 2C9enzyme
MeloxicamProstaglandin G/H synthase 1target
MeloxicamCytochrome P450 3A4enzyme
MeloxicamMultidrug resistance-associated protein 4transporter
Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MeloxicamCytochrome P450 2C8enzyme
MeloxicamSerum albumincarrier
MeloxicamHuman vesicular glutamate transporterstransporter
CarprofenProstaglandin G/H synthase 2target
CarprofenProstaglandin G/H synthase 1target
CarprofenSolute carrier family 22 member 6transporter
NalbuphineKappa-type opioid receptortarget
NalbuphineMu-type opioid receptortarget
NalbuphineDelta-type opioid receptortarget
LevorphanolMu-type opioid receptortarget
LevorphanolDelta-type opioid receptortarget
LevorphanolKappa-type opioid receptortarget
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
OxybuprocaineSodium channel protein type 10 subunit alphatarget
OxybuprocaineCholinesteraseenzyme
RemifentanilMu-type opioid receptortarget
RemifentanilDelta-type opioid receptortarget
RemifentanilKappa-type opioid receptortarget
CocaineSodium-dependent noradrenaline transportertarget
CocaineSodium channel proteintarget
CocaineSodium-dependent serotonin transportertarget
CocaineSodium-dependent dopamine transportertarget
CocaineCytochrome P450 3A4enzyme
CocaineMuscarinic acetylcholine receptor M1target
CocaineMuscarinic acetylcholine receptor M2target
CocaineCytochrome P450 2D6enzyme
CocaineSolute carrier family 22 member 2transporter
CocaineCytochrome P450 2C8enzyme
CocaineSigma non-opioid intracellular receptor 1target
CocaineLiver carboxylesterase 1target
CocaineCholinesteraseenzyme
CocaineSodium-dependent dopamine transportertransporter
Cocainealpha1-acid glycoproteincarrier
CocaineLiver carboxylesterase 1enzyme
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
BuprenorphineKappa-type opioid receptortarget
BuprenorphineMu-type opioid receptortarget
BuprenorphineCytochrome P450 3A4enzyme
BuprenorphineCytochrome P450 2D6enzyme
BuprenorphineP-glycoprotein 1transporter
BuprenorphineATP-binding cassette sub-family G member 2transporter
BuprenorphineCytochrome P450 2C9enzyme
BuprenorphineCytochrome P450 3A5enzyme
BuprenorphineCytochrome P450 2C8enzyme
BuprenorphineCytochrome P450 3A7enzyme
BuprenorphineDelta-type opioid receptortarget
BuprenorphineCytochrome P450 2C18enzyme
BuprenorphineCytochrome P450 2C19enzyme
BuprenorphineNociceptin receptortarget
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
HydrocodoneMu-type opioid receptortarget
HydrocodoneDelta-type opioid receptortarget
HydrocodoneCytochrome P450 3A4enzyme
HydrocodoneCytochrome P450 2D6enzyme
HydrocodoneCytochrome P450 2B6enzyme
HydrocodoneCytochrome P450 2C19enzyme
HydrocodoneSigma non-opioid intracellular receptor 1target
MepivacaineSodium channel protein type 10 subunit alphatarget
BromfenacProstaglandin G/H synthase 1target
BromfenacProstaglandin G/H synthase 2target
BromfenacProstaglandin G/H synthase 2enzyme
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
GabapentinAdenosine receptor A1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
GabapentinLarge neutral amino acids transporter small subunit 1transporter
GabapentinVoltage-dependent N-type calcium channeltarget
GabapentinPotassium voltage-gated channel subfamily KQT member 3target
GabapentinPotassium voltage-gated channel subfamily KQT member 5target
LevobupivacaineSodium channel protein type 10 subunit alphatarget
LevobupivacaineCytochrome P450 3A4enzyme
LevobupivacaineCytochrome P450 1A2enzyme
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
IbuprofenProstaglandin G/H synthase 1target
IbuprofenProstaglandin G/H synthase 2target
IbuprofenCytochrome P450 2C9enzyme
IbuprofenSerum albumincarrier
IbuprofenMultidrug resistance-associated protein 4transporter
IbuprofenMultidrug resistance-associated protein 1transporter
IbuprofenSolute carrier organic anion transporter family member 1A2transporter
IbuprofenSolute carrier family 22 member 6transporter
IbuprofenSolute carrier family 22 member 8transporter
IbuprofenSolute carrier family 22 member 11transporter
IbuprofenSolute carrier organic anion transporter family member 2B1transporter
IbuprofenP-glycoprotein 1transporter
IbuprofenUDP-glucuronosyltransferase 1-3enzyme
IbuprofenUDP-glucuronosyltransferase 1-9enzyme
IbuprofenUDP-glucuronosyltransferase 2B4enzyme
IbuprofenUDP-glucuronosyltransferase 2B7enzyme
IbuprofenCytochrome P450 2C8enzyme
IbuprofenCytochrome P450 2C19enzyme
IbuprofenApoptosis regulator Bcl-2target
IbuprofenThrombomodulintarget
IbuprofenFatty acid-binding protein, intestinaltarget
IbuprofenPeroxisome proliferator-activated receptor gammatarget
IbuprofenCystic fibrosis transmembrane conductance regulatortarget
IbuprofenPeroxisome proliferator-activated receptor alphatarget
IbuprofenPlatelet glycoprotein Ib alpha chaintarget
IbuprofenProtein S100-A7target
IbuprofenAlpha-methylacyl-CoA racemaseenzyme
IbuprofenCytochrome P450 3A4enzyme
DiphenoxylateMu-type opioid receptortarget
DiphenoxylateDelta-type opioid receptortarget
BenzocaineSodium channel protein type 10 subunit alphatarget
BenzocaineP-glycoprotein 1transporter
BenzocaineLiver carboxylesterase 1enzyme
ChloroprocaineSodium channel protein type 10 subunit alphatarget
ChloroprocaineSodium-dependent dopamine transportertarget
ChloroprocaineCholinesteraseenzyme
NaloxoneMu-type opioid receptortarget
NaloxoneEstrogen receptor alphatarget
NaloxoneCyclic AMP-responsive element-binding protein 1target
NaloxoneDelta-type opioid receptortarget
NaloxoneSolute carrier organic anion transporter family member 1A2transporter
NaloxoneP-glycoprotein 1transporter
NaloxoneKappa-type opioid receptortarget
NaloxoneCytochrome P450 3A4enzyme
NaloxoneSerum albumincarrier
NaloxoneToll-like receptor 4target
NaloxoneLiver carboxylesterase 1target
NaloxoneUDP-glucuronosyltransferase 1-1enzyme
OxymorphoneMu-type opioid receptortarget
OxymorphoneCytochrome P450 2D6enzyme
OxymorphoneDelta-type opioid receptortarget
OxymorphoneCytochrome P450 3A4enzyme
MitoxantroneDNA topoisomerase 2-alphatarget
MitoxantroneCytochrome P450 2E1enzyme
MitoxantroneP-glycoprotein 1transporter
MitoxantroneMultidrug resistance-associated protein 1transporter
MitoxantroneATP-binding cassette sub-family G member 2transporter
MitoxantroneDNAtarget
MitoxantroneCytochrome P450 1B1enzyme
MitoxantroneCytochrome P450 3A4enzyme
DezocineMu-type opioid receptortarget
DezocineKappa-type opioid receptortarget
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineCholinesterasetarget
KetamineNitric oxide synthase, braintarget
LevacetylmethadolMu-type opioid receptortarget
LevacetylmethadolCytochrome P450 3A4enzyme
LevacetylmethadolNeuronal acetylcholine receptor subunit beta-4target
LevacetylmethadolNeuronal acetylcholine receptor subunit alpha-3target
LevacetylmethadolCytochrome P450 3A5enzyme
LevacetylmethadolCytochrome P450 3A7enzyme
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
Methadyl acetateMu-type opioid receptortarget
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
DiamorphineMu-type opioid receptortarget
DiamorphineKappa-type opioid receptortarget
DiamorphineDelta-type opioid receptortarget
DiamorphineLiver carboxylesterase 1target
DiamorphineThyroxine-binding globulincarrier
EthylmorphineCytochrome P450 2D6enzyme
EthylmorphineNADPH--cytochrome P450 reductaseenzyme
EthylmorphineMu-type opioid receptortarget
EthylmorphineCytochrome P450 2B6enzyme
EthylmorphineCytochrome P450 3A4enzyme
EtorphineE3 ubiquitin-protein ligase TRIM13target
EtorphinePro-opiomelanocortintarget
EtorphineMu-type opioid receptortarget
EtorphineDelta-type opioid receptortarget
EtorphineKappa-type opioid receptortarget
EtorphineNociceptin receptortarget
CarfentanilMu-type opioid receptortarget
CarfentanilKappa-type opioid receptortarget
CarfentanilDelta-type opioid receptortarget
DiprenorphineE3 ubiquitin-protein ligase TRIM13target
DiprenorphineDelta-type opioid receptortarget
DiprenorphineKappa-type opioid receptortarget
DiprenorphineMu-type opioid receptortarget
DihydrocodeineCytochrome P450 2D6enzyme
DihydrocodeineCytochrome P450 3A4enzyme
DihydromorphineE3 ubiquitin-protein ligase TRIM13target
DihydromorphinePro-opiomelanocortintarget
DihydromorphineMu-type opioid receptortarget
DihydromorphineDelta-type opioid receptortarget
DihydromorphineKappa-type opioid receptortarget
3-MethylfentanylMu-type opioid receptortarget
3-MethylfentanylDelta-type opioid receptortarget
3-MethylfentanylKappa-type opioid receptortarget
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
CastanospermineGlucan 1,3-beta-glucosidasetarget
7-NitroindazoleNitric oxide synthase, endothelialtarget
7-NitroindazoleNitric oxide synthase, inducibletarget
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneSerum albumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
MethylecgonineIg gamma-2 chain C regiontarget
MethylecgonineIg kappa chain C regiontarget
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
MetamizoleProstaglandin G/H synthase 1target
MetamizoleCytochrome P450 2B6enzyme
MetamizoleCytochrome P450 3A4enzyme
ZomepiracProstaglandin D2 receptor 2target
ZomepiracCytochrome P450 3A4enzyme
ZomepiracSerum albumincarrier
VapreotideNeurokinin 1 receptortarget
VapreotideSomatostatin receptor type 2target
VapreotideSomatostatin receptor type 5target
VapreotideCytochrome P450 3A4enzyme
LofexidineAlpha-2A adrenergic receptortarget
LofexidineAlpha-1A adrenergic receptortarget
Lofexidine5-hydroxytryptamine receptor 1Atarget
Lofexidine5-hydroxytryptamine receptor 7target
Lofexidine5-hydroxytryptamine receptor 2Ctarget
Lofexidine5-hydroxytryptamine receptor 1Dtarget
LofexidineCytochrome P450 2D6enzyme
LofexidineCytochrome P450 1A2enzyme
LofexidineCytochrome P450 2C19enzyme
LofexidineATP-binding cassette sub-family B member 5transporter
LofexidineMultidrug and toxin extrusion protein 1transporter
PirfenidoneFurintarget
PirfenidoneCytochrome P450 1A2enzyme
TetrodotoxinSodium channel protein type 1 subunit alphatarget
TetrodotoxinSodium channel protein type 2 subunit alphatarget
TetrodotoxinSodium channel protein type 3 subunit alphatarget
TetrodotoxinSodium channel protein type 8 subunit alphatarget
CanertinibEpidermal growth factor receptortarget
AndrographolideTumor necrosis factortarget
AndrographolideInterleukin-1 betatarget
AndrographolideInterleukin-6target
AndrographolideNuclear factor NF-kappa-B p100 subunittarget
AndrographolideNuclear factor NF-kappa-B p105 subunittarget
PizotifenMuscarinic acetylcholine receptor M2target
PizotifenMuscarinic acetylcholine receptor M1target
PizotifenMuscarinic acetylcholine receptor M3target
Pizotifen5-hydroxytryptamine receptor 2Atarget
Pizotifen5-hydroxytryptamine receptor 2Btarget
Pizotifen5-hydroxytryptamine receptor 2Ctarget
PizotifenHistamine H1 receptortarget
Pizotifen5-hydroxytryptamine receptor 1Atarget
Pizotifen5-hydroxytryptamine receptor 1Btarget
Pizotifen5-hydroxytryptamine receptor 1Dtarget
PizotifenAlpha-1A adrenergic receptortarget
PizotifenAlpha-1B adrenergic receptortarget
PizotifenAlpha-1D adrenergic receptortarget
PizotifenAlpha-2A adrenergic receptortarget
PizotifenAlpha-2B adrenergic receptortarget
PizotifenAlpha-2C adrenergic receptortarget
PizotifenUDP-glucuronosyltransferase 2B10enzyme
IcatibantB2 bradykinin receptortarget
IcatibantAminopeptidase Ntarget
NalmefeneMu-type opioid receptortarget
NalmefeneKappa-type opioid receptortarget
NalmefeneDelta-type opioid receptortarget
NalmefeneUDP-glucuronosyltransferase 2B7enzyme
NalmefeneUDP-glucuronosyltransferase 1-3enzyme
NalmefeneUDP-glucuronosyltransferase 1-8enzyme
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
ExisulindcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
ExisulindcGMP-specific 3',5'-cyclic phosphodiesterasetarget
ExisulindcGMP-dependent 3',5'-cyclic phosphodiesterasetarget
ExisulindGlutathione S-transferase Ptarget
ExisulindAldose reductasetarget
ExisulindAldo-keto reductase family 1 member B10target
ZiconotideVoltage-dependent N-type calcium channel subunit alpha-1Btarget
ZiconotideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
GaboxadolProton-coupled amino acid transporter 1transporter
FlupirtineAlpha-2A adrenergic receptortarget
LornoxicamCytochrome P450 2C9enzyme
LornoxicamProstaglandin G/H synthase 1target
LornoxicamProstaglandin G/H synthase 2target
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
ZaltoprofenUDP-glucuronosyltransferase 2B7enzyme
ZaltoprofenCytochrome P450 2C9enzyme
ZaltoprofenProstaglandin G/H synthase 1enzyme
KetobemidoneProstaglandin G/H synthase 1enzyme
KetobemidoneCytochrome P450 2C9enzyme
KetobemidoneCytochrome P450 3A4enzyme
KetobemidoneUDP-glucuronosyltransferase 1-9enzyme
KetobemidoneCytochrome P450 2B6enzyme
KetobemidoneCytochrome P450 2C19enzyme
KetobemidoneCytochrome P450 2C8enzyme
KetobemidoneMu-type opioid receptortarget
KetobemidoneKappa-type opioid receptortarget
KetobemidoneDelta-type opioid receptortarget
KetobemidoneNMDA receptortarget
SeratrodastCytochrome P450 2C9enzyme
SeratrodastCytochrome P450 3A4enzyme
SeratrodastCytochrome P450 2C8enzyme
SeratrodastCytochrome P450 2C19enzyme
SeratrodastCytochrome P450 2B6enzyme
SeratrodastUDP-glucuronosyltransferase 1-9enzyme
SeratrodastProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2A6enzyme
SeratrodastThromboxane A2 receptortarget
DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DrotaverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
Benzyl alcoholCytochrome P450 2C8enzyme
Benzyl alcoholCytochrome P450 1A1enzyme
Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
Benzyl alcoholCytochrome P450 1A2enzyme
Benzyl alcoholCytochrome P450 2E1enzyme
Benzyl alcoholCytochrome P450 2D6enzyme
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
MethylnaltrexoneMu-type opioid receptortarget
MethylnaltrexoneKappa-type opioid receptortarget
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
AzapropazoneSerum albumincarrier
FelbinacCathepsin L1target
TranilastHematopoietic prostaglandin D synthasetarget
TranilastCytochrome P450 3A4enzyme
TranilastCytochrome P450 2C9enzyme
EpibatidineCHRNA7-FAM7A fusion proteintarget
EpibatidineNeuronal acetylcholine receptor subunit alpha-7target
EpibatidineNeuronal acetylcholine receptor subunit beta-2target
EpibatidineNeuronal acetylcholine receptor subunit alpha-2target
EpibatidineNeuronal acetylcholine receptor subunit alpha-3target
EpibatidineNeuronal acetylcholine receptor subunit alpha-4target
EpibatidineNeuronal acetylcholine receptor subunit beta-4target
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
ParecoxibLactotransferrintarget
ParecoxibProstaglandin G/H synthase 2target
ParecoxibCytochrome P450 3A4enzyme
ParecoxibCytochrome P450 2C9enzyme
DPDPESolute carrier organic anion transporter family member 1B3transporter
TeriflunomideATP-binding cassette sub-family G member 2transporter
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideCytochrome P450 2C8enzyme
TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
TeriflunomideCytochrome P450 1A2enzyme
EtofenamateThyroxine-binding globulincarrier
NaloxegolCytochrome P450 3A4enzyme
NaloxegolCytochrome P450 2D6enzyme
NaloxegolCytochrome P450 2C19enzyme
NaloxegolMu-type opioid receptortarget
TetracaineRyanodine receptor 1target
TetracaineRyanodine receptor 2target
TetracaineVoltage-gated sodium channel alpha subunittarget
PholcodineMu-type opioid receptortarget
PholcodineKappa-type opioid receptortarget
PholcodineDelta-type opioid receptortarget
LoxoprofenProstaglandin G/H synthase 2target
LoxoprofenProstaglandin G/H synthase 1target
LoxoprofenCarbonyl reductase [NADPH] 1enzyme
LoxoprofenCytochrome P450 3A Subfamilyenzyme
LoxoprofenUDP-glucuronosyltransferase 2B7enzyme
DroxicamProstaglandin G/H synthase 1target
DroxicamProstaglandin G/H synthase 2target
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
PropoxycaineLiver carboxylesterase 1enzyme
PropoxycaineVoltage-gated sodium channel alpha subunittarget
PramocaineVoltage-gated sodium channel alpha subunittarget
OpiumDelta-type opioid receptortarget
OpiumKappa-type opioid receptortarget
OpiumMu-type opioid receptortarget
OpiumSerum albumincarrier
OpiumBeta-2-microglobulincarrier
OpiumCytochrome P450 2D6enzyme
OpiumCytochrome P450 3A4enzyme
ButambenVoltage-dependent calcium channeltarget
ButambenCholinesteraseenzyme
ButambenAlpha-1-acid glycoprotein 1carrier
ButambenSerum albumincarrier
ButambenATP-sensitive potassium channeltarget
ButambenTransient receptor potential cation channel subfamily A member 1target
ButambenTransient receptor potential cation channel subfamily V member 4target
NonivamideTransient receptor potential cation channel subfamily V member 1target
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
XylazineAlpha-2 adrenergic receptorstarget
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
AnisodamineCytochrome P450 2D6enzyme
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
LisofyllineCytochrome P450 1A2enzyme
NitroaspirinProstaglandin G/H synthase 1target
NafamostatIntercellular adhesion molecule 1target
NafamostatTrypsin-1target
NafamostatKallikrein-1target
NafamostatProthrombintarget
NafamostatCoagulation factor Xtarget
NafamostatCoagulation factor XIItarget
NafamostatSolute carrier family 22 member 1transporter
NafamostatSolute carrier family 22 member 2transporter
AlclofenacProstaglandin G/H synthase 2target
BamifyllineCytochrome P450 1A2enzyme
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
WIN 55212-2Cytochrome P450 3A4enzyme
SC-236Cyclooxygenase 2target
SC-236Nuclear factor NF-kappa-B complextarget
NS-398Cyclooxygenase 2target
EbselenBifunctional epoxide hydrolase 2target
LicofeloneArachidonate 5-lipoxygenasetarget
LicofeloneProstaglandin G/H synthase 2target
LicofeloneGroup IIE secretory phospholipase A2target
LicofeloneCytochrome P450 2C9enzyme
LicofeloneCytochrome P450 2C8enzyme
LicofeloneCytochrome P450 2J2enzyme
LicofeloneUDP-glucuronosyltransferase 1-3enzyme
MilnacipranSodium-dependent serotonin transportertarget
MilnacipranSodium-dependent noradrenaline transportertarget
MilnacipranNMDA receptortarget
MilnacipranCytochrome P450 3A4enzyme
EcallantidePlasma kallikreintarget
RI 624Beta-nerve growth factortarget
TapentadolMu-type opioid receptortarget
TapentadolKappa-type opioid receptortarget
TapentadolDelta-type opioid receptortarget
TapentadolSodium-dependent noradrenaline transportertarget
Tapentadol5-hydroxytryptamine receptor 3Atarget
TapentadolUDP-glucuronosyltransferase 1-9enzyme
TapentadolUDP-glucuronosyltransferase 2B7enzyme
TapentadolCytochrome P450 2D6enzyme
TapentadolCytochrome P450 2C9enzyme
TapentadolCytochrome P450 2C19enzyme
TapentadolSodium-dependent serotonin transportertarget
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
NabiximolsCannabinoid receptor 1target
NabiximolsCannabinoid receptor 2target
NabiximolsG-protein coupled receptor 12target
NabiximolsCytochrome P450 2C9enzyme
NabiximolsCytochrome P450 2C19enzyme
NabiximolsCytochrome P450 2D6enzyme
NabiximolsCytochrome P450 3A4enzyme
NabiximolsGlycine receptor subunit alpha-1target
NabiximolsGlycine receptor (alpha-1/beta)target
NabiximolsGlycine receptor subunit alpha-3target
NabiximolsN-arachidonyl glycine receptortarget
NabiximolsG-protein coupled receptor 55target
Nabiximols5-hydroxytryptamine receptor 1Atarget
Nabiximols5-hydroxytryptamine receptor 2Atarget
NabiximolsNeuronal acetylcholine receptor subunit alpha-7target
NabiximolsDelta-type opioid receptortarget
NabiximolsMu-type opioid receptortarget
NabiximolsPeroxisome proliferator-activated receptor gammatarget
NabiximolsCytochrome P450 3A5enzyme
NabiximolsArachidonate 5-lipoxygenaseenzyme
NabiximolsArachidonate 15-lipoxygenaseenzyme
NabiximolsMultidrug resistance-associated protein 1transporter
NabiximolsATP-binding cassette sub-family G member 2transporter
NabiximolsEquilibrative nucleoside transporter 1transporter
NabiximolsTransient receptor potential cation channel subfamily V member 1target
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NabiximolsVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NabiximolsTransient receptor potential cation channel subfamily A member 1target
NabiximolsTransient receptor potential cation channel subfamily M member 8target
NabiximolsTransient receptor potential cation channel subfamily V member 2target
NabiximolsTransient receptor potential cation channel subfamily V member 3target
NabiximolsTransient receptor potential cation channel subfamily V member 4target
NabiximolsVoltage-dependent anion-selective channel protein 1target
NabiximolsProstaglandin G/H synthase 1target
NabiximolsProstaglandin G/H synthase 2target
NabiximolsAcetyl-CoA acetyltransferase, mitochondrialtarget
NabiximolsSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Nabiximols3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
NabiximolsGlutathione reductase, mitochondrialtarget
NabiximolsGlutathione peroxidase 1target
NabiximolsIndoleamine 2,3-dioxygenase 1target
NabiximolsArylalkylamine N-acetyltransferasetarget
NabiximolsCytochrome P450 1B1target
NabiximolsCytochrome P450 3A5target
NabiximolsCytochrome P450 2D6target
NabiximolsCytochrome P450 1A2target
NabiximolsCytochrome P450 1A1target
NabiximolsCytochrome P450 3A7target
NabiximolsQuinone oxidoreductasetarget
NabiximolsCatalasetarget
NabiximolsFatty-acid amide hydrolase 1target
NabiximolsSuperoxide dismutase [Cu-Zn]target
NabiximolsN-acylethanolamine-hydrolyzing acid amidasetarget
ErenumabCalcitonin gene-related peptide type 1 receptortarget
GalcanezumabCalcitonin gene-related peptide 1target
GalcanezumabCalcitonin gene-related peptide 2target
KelatorphanLeukotriene A-4 hydrolasetarget