Piperidines

A family of hexahydropyridines.
DrugDrug NameDrug Description
DB00278ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00350MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
DB00357AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
DB00376TrihexyphenidylAn antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS).
DB00419MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
DB00422MethylphenidateA stimulant used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
DB00434CyproheptadineA serotonin and histamine antagonist used in the treatment of allergy symptoms and in combination with epinephrine in the treatment of anaphylaxis.
DB00454MeperidineAn opioid agonist with analgesic and sedative properties used to manage severe pain.
DB00455LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
DB00480LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DB00491MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
DB00604CisaprideA medication used to treat heartburn associated with GERD.
DB00708SufentanilAn opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
DB00715ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
DB00719AzatadineAn H1 receptor antagonist used to treat perennial and allergic rhinitis as well as eustachian tube congestion.
DB00802AlfentanilAn opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
DB00810BiperidenA muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs.
DB00813FentanylAn opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
DB00836LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
DB00906TiagabineAn antiepileptic used to treat partial seizures.
DB00913AnileridineAn opioid analgesic used to treat moderate to severe pain.
DB00920KetotifenA histamine H1 receptor blocker used to treat mild asthma and allergic conjunctivitis.
DB00950FexofenadineA selective H1-antagonist for the symptomatic treatment of seasonal allergic rhinitis and chronic idiopathic urticaria.
DB00961MepivacaineA local anesthetic used for local or regional analgesia or anesthesia.
DB00967DesloratadineA second generation tricyclic antihistamine used to treat seasonal and non seasonal allergic rhinitis, pruritus, and urticaria.
DB01041ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
DB01074PerhexilineFor the management of severe angina pectoris.
DB01081DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
DB01107MethyprylonFor the treatment of insomnia.
DB01184DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
DB01195FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
DB01437GlutethimideFor the treatment of insomnia.
DB01478DesmethylprodineDesmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. It has been listed as a Schedule I controlled drug in the United States, and thus...
DB01501DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
DB01520TenocyclidineBecause of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors.
DB01535CarfentanilCarfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals.
DB015391-PiperidinocyclohexanecarbonitrileNot Available
DB01549RolicyclidineRolicyclidine has anesthetic properties and can induce a sedative effect.
DB01557α-Methylfentanylα-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
DB01570OhmefentanylOhmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl...
DB015713-Methylfentanyl3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be...
DB03206DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
DB03575PhencyclidineA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
DB04842FluspirileneAn antipsychotic agent used in the treatment of schizophrenia.
DB05018MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
DB05022AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
DB05137LobelineInvestigated for use/treatment in addictions.
DB06701DexmethylphenidateA norepinephrine-dopamine reuptake inhibitor used in the treatment of ADHD in conjunction with other therapies.
DB06738KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
DB08849Nipecotic acidNot Annotated
DB08910PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
DB08950IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
DB08997DexetimideA muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
DB091693-Allylfentanyl3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. Fentanyl and its analogs have killed thousands of people around the world as drugs of...
DB09172BrifentanilBrifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s. The effects...
DB09174LofentanilLofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more...
DB09175MirfentanilMirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in...
DB09179R-30490R-30490 is an opioid related to carfentanil used as an animal tranquilizer. It was first synthesized by Janssen Pharmaceutica as part of a structure-activity relationship study of fentanly and its...
DB09182BenzylfentanylBenzylfentanyl (R-4129) is a fentanyl analog opioid that was on the list of Schedule I drugs in America in 1985 due to its structural similarity to fentanyl. In 2010 it...
DB11614RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
DB11650HT-0712BLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
DB11702Antineoplaston A10Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
DB12412GemigliptinGemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction.
DB12465KetanserinKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
DB12492PiritramidePiritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
DB12693RitanserinRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
DB13160AlphaprodineNot Annotated
DB13413PhenglutarimideNot Annotated
DB13591MetopimazineNot Annotated
DB13605PhenoperidineNot Annotated
DB13791PenfluridolNot Annotated
DB13792ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
DB14661Loperamide oxideNot Annotated
DB06422TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB14074IcaridinIcaridin is indicated for use to repel insects, such as mosquitoes, biting flies, ticks, chiggers, and fleas, via topical use or over clothing .
DB04545AfegostatNot Available
DB14857AvadomideAvadomide is under investigation in clinical trial NCT02031419 (Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma).
DB15360Carfentanil, C-11Carfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain).
DB00843DonepezilAn acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
DB00899RemifentanilAn opioid analgesic used in anesthesia.
DB06155RimonabantFor use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated...
DB08865CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
DB09173ButyrfentanylA methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug.
DB14872LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
DB15011AvacopanAvacopan is under investigation in clinical trial NCT02994927 (A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis).
DrugDrug NameTargetType
DB00278ArgatrobanProthrombintarget
DB00278ArgatrobanCytochrome P450 3A4enzyme
DB00278ArgatrobanCytochrome P450 3A5enzyme
DB00278ArgatrobanSerum albumincarrier
DB00278Argatrobanalpha1-acid glycoproteincarrier
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineP-glycoprotein 1transporter
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00342TerfenadineBile salt export pumptransporter
DB00350MinoxidilATP-sensitive inward rectifier potassium channel 1target
DB00350MinoxidilProstaglandin G/H synthase 1target
DB00350MinoxidilRenintarget
DB00350MinoxidilUDP-glucuronosyltransferase 1-1enzyme
DB00357AminoglutethimideCytochrome P450 19A1target
DB00357AminoglutethimideCytochrome P450 2C19enzyme
DB00357AminoglutethimideCytochrome P450 3A4enzyme
DB00357AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M1target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M2target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M3target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M4target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M5target
DB00419MiglustatCeramide glucosyltransferasetarget
DB00422MethylphenidateSodium-dependent dopamine transportertarget
DB00422MethylphenidateSodium-dependent noradrenaline transportertarget
DB00422MethylphenidateCarboxylesteraseenzyme
DB00422Methylphenidate5-hydroxytryptamine receptor 1Atarget
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00454MeperidineKappa-type opioid receptortarget
DB00454MeperidineCytochrome P450 2D6enzyme
DB00454MeperidineCytochrome P450 2B6enzyme
DB00454MeperidineGlutamate receptor ionotropic, NMDA 1target
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB00454MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB00454MeperidineCytochrome P450 2C19enzyme
DB00454MeperidineCytochrome P450 3A4enzyme
DB00454MeperidineSerum albumincarrier
DB00454MeperidineAlpha-1-acid glycoprotein 1carrier
DB00454MeperidineMuscarinic acetylcholine receptortarget
DB00454MeperidineMu-type opioid receptortarget
DB00454MeperidineSodium-dependent dopamine transportertarget
DB00454MeperidineSodium-dependent noradrenaline transportertarget
DB00454MeperidineSodium-dependent serotonin transportertarget
DB00454MeperidineLiver carboxylesterase 1target
DB00454MeperidineCytochrome P450 1A2enzyme
DB00455LoratadineHistamine H1 receptortarget
DB00455LoratadineCytochrome P450 3A4enzyme
DB00455LoratadineCytochrome P450 2C19enzyme
DB00455LoratadineCytochrome P450 2D6enzyme
DB00455LoratadineCytochrome P450 2C8enzyme
DB00455LoratadineP-glycoprotein 1transporter
DB00455LoratadinePotassium voltage-gated channel subfamily H member 2target
DB00455LoratadineBile salt export pumptransporter
DB00455LoratadineCytochrome P450 1A1enzyme
DB00455LoratadineCytochrome P450 1A2enzyme
DB00455LoratadineCytochrome P450 2B6enzyme
DB00455LoratadineCytochrome P450 2C9enzyme
DB00455LoratadineCytochrome P450 3A5enzyme
DB00455LoratadineUDP-glucuronosyltransferase 2B10enzyme
DB00455LoratadineUDP-glucuronosyltransferase 1-1enzyme
DB00455LoratadineUDP-glucuronosyltransferase 1-3enzyme
DB00455LoratadineUDP-glucuronosyltransferase 2B15enzyme
DB00480LenalidomideProstaglandin G/H synthase 2target
DB00480LenalidomideTumor necrosis factor ligand superfamily member 11target
DB00480LenalidomideCadherin-5target
DB00480LenalidomideProtein cereblontarget
DB00480LenalidomideP-glycoprotein 1transporter
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00708SufentanilMu-type opioid receptortarget
DB00708SufentanilDelta-type opioid receptortarget
DB00708SufentanilKappa-type opioid receptortarget
DB00708SufentanilCytochrome P450 3A4enzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineP-glycoprotein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00715ParoxetineAlpha-1 adrenergic receptorstarget
DB00715ParoxetineAlpha-2 adrenergic receptorstarget
DB00715ParoxetineBeta adrenergic receptortarget
DB00715ParoxetineDopamine D2 receptortarget
DB00715ParoxetineHistamine H1 receptortarget
DB00715ParoxetineSerotonin Receptorstarget
DB00715ParoxetineMuscarinic acetylcholine receptortarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineD(1) dopamine receptortarget
DB00715ParoxetineCytochrome P450 2C19enzyme
DB00719AzatadineHistamine H1 receptortarget
DB00719AzatadineCytochrome P450 3A4enzyme
DB00802AlfentanilMu-type opioid receptortarget
DB00802AlfentanilCytochrome P450 3A4enzyme
DB00802AlfentanilCytochrome P450 3A5enzyme
DB00802AlfentanilAlpha-1-acid glycoprotein 1carrier
DB00802AlfentanilSerum albumincarrier
DB00802AlfentanilCytochrome P450 3A7enzyme
DB00802AlfentanilP-glycoprotein 1transporter
DB00810BiperidenNeuronal acetylcholine receptor subunit alpha-2target
DB00810BiperidenMuscarinic acetylcholine receptor M1target
DB00810BiperidenCytochrome P450 2D6enzyme
DB00813FentanylMu-type opioid receptortarget
DB00813FentanylDelta-type opioid receptortarget
DB00813FentanylCytochrome P450 3A4enzyme
DB00813FentanylCytochrome P450 3A7enzyme
DB00813FentanylP-glycoprotein 1transporter
DB00813FentanylKappa-type opioid receptortarget
DB00813FentanylP-glycoprotein 1target
DB00813FentanylSerum albumincarrier
DB00813Fentanylalpha1-acid glycoproteincarrier
DB00836LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00836LoperamideMu-type opioid receptortarget
DB00836LoperamideCalmodulintarget
DB00836LoperamidePro-opiomelanocortintarget
DB00836LoperamideDelta-type opioid receptortarget
DB00836LoperamideCytochrome P450 3A4enzyme
DB00836LoperamideP-glycoprotein 1transporter
DB00836LoperamideKappa-type opioid receptortarget
DB00836LoperamideCytochrome P450 2C8enzyme
DB00836LoperamideCytochrome P450 2B6enzyme
DB00836LoperamideCytochrome P450 2D6enzyme
DB00836LoperamideNuclear receptor subfamily 1 group I member 3target
DB00906TiagabineSodium- and chloride-dependent GABA transporter 1target
DB00906TiagabineCytochrome P450 3A4enzyme
DB00906TiagabineUDP-glucuronosyltransferase 1-1enzyme
DB00913AnileridineMu-type opioid receptortarget
DB00920KetotifenHistamine H1 receptortarget
DB00920Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00950FexofenadineHistamine H1 receptortarget
DB00950FexofenadineP-glycoprotein 1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 2B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1A2transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B3transporter
DB00950FexofenadineSolute carrier family 22 member 8transporter
DB00950FexofenadineCanalicular multispecific organic anion transporter 1transporter
DB00950FexofenadineCanalicular multispecific organic anion transporter 2transporter
DB00950FexofenadineSerum albumincarrier
DB00950Fexofenadinealpha1-acid glycoproteincarrier
DB00961MepivacaineSodium channel protein type 10 subunit alphatarget
DB00967DesloratadineHistamine H1 receptortarget
DB00967DesloratadineP-glycoprotein 1transporter
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideDNAtarget
DB01041ThalidomideProtein cereblontarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
DB01074PerhexilineCytochrome P450 2D6enzyme
DB01074PerhexilineCytochrome P450 2B6enzyme
DB01074PerhexilineCytochrome P450 3A4enzyme
DB01074PerhexilinePotassium voltage-gated channel subfamily H member 2target
DB01081DiphenoxylateMu-type opioid receptortarget
DB01081DiphenoxylateDelta-type opioid receptortarget
DB01107MethyprylonGamma-aminobutyric acid receptor subunit alpha-1target
DB01107MethyprylonGABA-A receptor (anion channel)target
DB01184DomperidoneDopamine D2 receptortarget
DB01184DomperidoneCytochrome P450 3A4enzyme
DB01184DomperidoneCytochrome P450 3A5enzyme
DB01184DomperidoneCytochrome P450 3A7enzyme
DB01184DomperidoneP-glycoprotein 1transporter
DB01184DomperidoneCytochrome P450 1A2enzyme
DB01184DomperidoneCytochrome P450 2B6enzyme
DB01184DomperidoneCytochrome P450 2C8enzyme
DB01184DomperidoneCytochrome P450 2D6enzyme
DB01184DomperidoneDopamine D3 receptortarget
DB01195FlecainideSodium channel protein type 5 subunit alphatarget
DB01195FlecainideCytochrome P450 2D6enzyme
DB01195FlecainideSodium channel protein type 4 subunit alphatarget
DB01195FlecainideCytochrome P450 2C9enzyme
DB01195FlecainidePotassium voltage-gated channel subfamily H member 2target
DB01195Flecainidealpha1-acid glycoproteincarrier
DB01195FlecainideSerum albumincarrier
DB01195FlecainideCytochrome P450 1A2enzyme
DB01195FlecainideP-glycoprotein 1transporter
DB01195FlecainideMultidrug and toxin extrusion protein 1transporter
DB01195FlecainideRyanodine receptor 2target
DB01437GlutethimideCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01437GlutethimideGamma-aminobutyric acid receptor subunit alpha-1target
DB01437GlutethimideGABA-A receptor (anion channel)target
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 3Btarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Atarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Btarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01520TenocyclidineAlpha-7 nicotinic cholinergic receptor subunittarget
DB01535CarfentanilMu-type opioid receptortarget
DB01535CarfentanilKappa-type opioid receptortarget
DB01535CarfentanilDelta-type opioid receptortarget
DB01549RolicyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB01549RolicyclidineDopamine D2 receptortarget
DB015713-MethylfentanylMu-type opioid receptortarget
DB015713-MethylfentanylDelta-type opioid receptortarget
DB015713-MethylfentanylKappa-type opioid receptortarget
DB03206DuvoglustatCyclomaltodextrin glucanotransferasetarget
DB03206DuvoglustatBeta-glucosidase Atarget
DB03206DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB03206DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB03206DuvoglustatXylose isomerasetarget
DB03575PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB03575PhencyclidineSigma non-opioid intracellular receptor 1target
DB03575PhencyclidineCytochrome P450 2B6enzyme
DB04842FluspirileneDopamine D2 receptortarget
DB04842Fluspirilene5-hydroxytryptamine receptor 2Atarget
DB04842FluspirileneVoltage-dependent calcium channel gamma-1 subunittarget
DB04842FluspirileneCytochrome P450 3A4enzyme
DB05018MigalastatAlpha-galactosidase Atarget
DB05018MigalastatUDP-glucuronosyltransferase 1-1enzyme
DB05022AmonafideDNA topoisomerase 2-alphatarget
DB05022AmonafideDNA topoisomerase 2-betatarget
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-9target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-10target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-7target
DB06701DexmethylphenidateSodium-dependent dopamine transportertarget
DB06701DexmethylphenidateSodium-dependent noradrenaline transportertarget
DB06701DexmethylphenidateSodium-dependent serotonin transportertarget
DB06701DexmethylphenidateCarboxylesteraseenzyme
DB06738KetobemidoneProstaglandin G/H synthase 1enzyme
DB06738KetobemidoneCytochrome P450 2C9enzyme
DB06738KetobemidoneCytochrome P450 3A4enzyme
DB06738KetobemidoneUDP-glucuronosyltransferase 1-9enzyme
DB06738KetobemidoneCytochrome P450 2B6enzyme
DB06738KetobemidoneCytochrome P450 2C19enzyme
DB06738KetobemidoneCytochrome P450 2C8enzyme
DB06738KetobemidoneMu-type opioid receptortarget
DB06738KetobemidoneKappa-type opioid receptortarget
DB06738KetobemidoneDelta-type opioid receptortarget
DB06738KetobemidoneNMDA receptortarget
DB08849Nipecotic acidProton-coupled amino acid transporter 1transporter
DB08910PomalidomideCytochrome P450 1A2enzyme
DB08910PomalidomideCytochrome P450 3A4enzyme
DB08910PomalidomideP-glycoprotein 1transporter
DB08910PomalidomideProtein cereblontarget
DB08910PomalidomideTumor necrosis factortarget
DB08910PomalidomideProstaglandin G/H synthase 2target
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB11614RupatadineCytochrome P450 3A4enzyme
DB11614RupatadineCytochrome P450 2C9enzyme
DB11614RupatadineCytochrome P450 2C19enzyme
DB11614RupatadineCytochrome P450 2D6enzyme
DB11614RupatadinePlatelet-activating factor receptortarget
DB11614RupatadineHistamine H1 receptortarget
DB12465Ketanserin5-hydroxytryptamine receptor 2Atarget
DB12693Ritanserin5-hydroxytryptamine receptor 2Atarget
DB12693RitanserinCytochrome P450 2D6enzyme
DB13791PenfluridolCytochrome P450 3A4enzyme
DB06422Ticalopride5-hydroxytryptamine receptor 4target
DB06422Ticalopride5-hydroxytryptamine receptor 3Atarget
DB14074IcaridinOdorant binding proteintarget
DB04545AfegostatEndoglucanase 5Atarget
DB04545AfegostatBeta-glucosidase Atarget
DB04545AfegostatPossible cellulase CelA1 (Endoglucanase) (Endo-1,4-beta-glucanase) (FI-cmcase) (Carboxymethyl cellulase)target
DB00843DonepezilAcetylcholinesterasetarget
DB00843Donepezil5-hydroxytryptamine receptor 2Atarget
DB00843DonepezilCytochrome P450 3A4enzyme
DB00843DonepezilCytochrome P450 2D6enzyme
DB00843DonepezilCytochrome P450 2C9enzyme
DB00843DonepezilCholinesterasetarget
DB00843DonepezilNitric oxide synthase, braintarget
DB00843DonepezilTumor necrosis factor-inducible gene 6 proteintarget
DB00843DonepezilInterleukin-1 betatarget
DB00843DonepezilNuclear factor NF-kappa-Btarget
DB00843DonepezilATP-binding cassette sub-family G member 2transporter
DB00843DonepezilP-glycoprotein 1transporter
DB00843DonepezilNMDA receptortarget
DB00899RemifentanilMu-type opioid receptortarget
DB00899RemifentanilDelta-type opioid receptortarget
DB00899RemifentanilKappa-type opioid receptortarget
DB06155RimonabantCannabinoid receptor 1target
DB06155RimonabantCytochrome P450 3A4enzyme
DB06155RimonabantG-protein coupled receptor 55target
DB08865CrizotinibCytochrome P450 3A4enzyme
DB08865CrizotinibCytochrome P450 3A5enzyme
DB08865CrizotinibP-glycoprotein 1transporter
DB08865CrizotinibALK tyrosine kinase receptortarget
DB08865CrizotinibHepatocyte growth factor receptortarget
DB08865CrizotinibCytochrome P450 2B6enzyme
DB08865CrizotinibCytochrome P450 3A Subfamilyenzyme
DB09173ButyrfentanylMu-type opioid receptortarget
DB09173ButyrfentanylKappa-type opioid receptortarget
DB09173ButyrfentanylDelta-type opioid receptortarget
DB09173ButyrfentanylCytochrome P450 3A4enzyme
DB09173ButyrfentanylCytochrome P450 2D6enzyme