Piperidines

A family of hexahydropyridines.
DrugDrug NameDrug Indication
DB00278ArgatrobanArgatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention.
DB00297BupivacaineFor the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.
DB00342TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DB00350MinoxidilFor the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia.
DB00357AminoglutethimideFor the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast.
DB00376TrihexyphenidylIndicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs.
DB00419MiglustatFor the treatment of adult patients with mild to moderate type 1 (nonneuropathic) Gaucher's disease for whom enzyme replacement therapy is not a therapeutic option (e.g. due to constraints such as allergy, hypersensitivity, or poor venous access). Now approved in some countries for the treatment of progressive neurological symptoms in adult and pediatric patients with Niemann-Pick disease type C (NP-C).
DB00422MethylphenidateFor use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
DB00434CyproheptadineFor treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.
DB00454PethidineUsed to control moderate to severe pain.
DB00455LoratadineA self-medication that is used alone or in combination with pseudoephedrine sulfate for the symptomatic relief of seasonal allergic rhinitis. Also used for the symptomatic relief of pruritus, erythema, and urticaria associated with chronic idiopathic urticaria in patients (not for children under 6 unless directed by a clincian).
DB00480LenalidomideLenalidomide is indicated for the treatment of multiple myeloma in combination with dexamethasone. It is also indicated for the treatment of patients with transfusion-dependent anemia due to low- or intermediate- risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities.
DB00491MiglitolFor use as an adjunct to diet to improve glycemic control in patients with non-insulin-dependent diabetes mellitus (NIDDM) whose hyperglycemia cannot be managed with diet alone.
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00708SufentanilUsed as an analgesic adjunct in anesthesia and as a primary anesthetic drug in procedures requiring assisted ventilation and in the relief of pain.
DB00715ParoxetineLabeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause.
DB00719AzatadineFor the relief of the symptoms of upper respiratory mucosal congestion in perennial and allergic rhinitis, and for the relief of nasal congestion and eustachian t.b. congestion.
DB00802AlfentanilFor the management of postoperative pain and the maintenance of general anesthesia.
DB00810BiperidenFor use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.
DB00813FentanylFor the treatment of cancer patients with severe pain that breaks through their regular narcotic therapy.
DB00836LoperamideFor the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies.
DB00906TiagabineFor the treatment of partial seizures
DB00913AnileridineFor treatment and management of pain (systemic) and for use as an anesthesia adjunct.
DB00920KetotifenIndicated as an add-on or prophylactic oral medication in the chronic treatment of mild atopic asthmatic children. Also used as self-medication for the temporary relief of itching of the eye due to allergic conjunctivitis (ophthalmic).
DB00950FexofenadineFor management of Seasonal allergic rhinitis
DB00961MepivacaineFor production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
DB00967DesloratadineFor the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
DB01002LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
DB01041ThalidomideFor the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence.
DB01074PerhexilineFor the management of severe angina pectoris.
DB01081DiphenoxylateFor as adjunctive therapy in the management of diarrhea
DB01107MethyprylonFor the treatment of insomnia.
DB01184DomperidoneFor management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
DB01195FlecainideFlecainide is is a class Ic antiarrhythmic agent and as such, it is used for the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin.
DB01437GlutethimideFor the treatment of insomnia.
DB01478desmethylprodineNot Available
DB01501DifenoxinMotofen(R) is a combination of atropine, an anticholinergic drug, and difenoxin, an antidiarrheal drug. It has been used in many countries for many years as a second line opioid-agonist antidiarrheal, which exists an intermediate between loperamide and paragoric. [2] Diarrhea which is a result of cyclic or diarrhea predominant Inflammatory Bowel Syndrome may not be treated effectively with difenoxin, diphenoxylate, or loperamide. As such, diarrhea and cramping which does not respond to non-centrally acting derivatives or belladonna derivatives such as atropine are often treated with conservative doses of codeine. In patients with acute ulcerative colitis, as induction of toxic megacolon is possible, and thus use of Motofen(R) is cautioned. Motofen(R) has been assigned pregnancy category C by the FDA, and is to be used only when the potential benefits outweigh the potential risk to the fetus. The safety of use during lactation is unknown and thus not recommended.
DB01520TenocyclidineBecause of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors.
DB01535CarfentanilCarfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals.
DB015391-PiperidinocyclohexanecarbonitrileNot Available
DB01549RolicyclidineRolicyclidine has anesthetic properties and can induce a sedative effect.
DB01557α-MethylfentanylNot Available
DB01570OhmefentanylNot Available
DB015713-MethylfentanylNot Available
DB03206DuvoglustatNot Available
DB03575PhencyclidineNot Available
DB039551-deoxymannojirimycinNot Available
DB04842FluspirileneUsed for the treatment of schizophrenia.
DB05018MigalastatInvestigated for use/treatment in fabry disease.
DB05022AmonafideInvestigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
DB05137LobelineInvestigated for use/treatment in addictions.
DB05676ApremilastInvestigated for use/treatment in psoriasis and psoriatic disorders.
DB06701DexmethylphenidateDexmethylphenidate is used as a treatment for ADHD, ideally in conjunction with psychological, educational, behavioral or other forms of treatment.
DB06738KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
DB08910PomalidomidePomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
DB08950IndoraminNot Available
DB08997DexetimideNot Available
DB091693-AllylfentanylNot Available
DB09172BrifentanilNot Available
DB09174LofentanilNot Available
DB09175MirfentanilNot Available
DB09179R-30490Not Available
DB09182BenzylfentanylNot Available
DB11614RupatadineFor the symptomatic relief of nasal and non-nasal symptoms of seasonal allergic rhinitis and perennial allergic rhinitis in patients 2 years of age and older [FDA Label]. Also used for the symptomatic relief of chronic spontaneous urticaria in patients 2 years of age and older.
DB11650HT-0712Not Available
DB11702Antineoplaston A10Not Available
DB12412GemigliptinNot Available
DB12465KetanserinNot Available
DB12492PiritramideNot Available
DB12693RitanserinNot Available
DB13160AlphaprodineNot Available
DB13792ClopamideNot Available
DrugDrug NameTargetType
DB00278ArgatrobanProthrombintarget
DB00278ArgatrobanCytochrome P450 3A4enzyme
DB00278ArgatrobanCytochrome P450 3A5enzyme
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 1A2enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB00342TerfenadineHistamine H1 receptortarget
DB00342TerfenadinePotassium voltage-gated channel subfamily H member 2target
DB00342TerfenadineCytochrome P450 3A4enzyme
DB00342TerfenadineCytochrome P450 2C9enzyme
DB00342TerfenadineCytochrome P450 2D6enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M3target
DB00342TerfenadineCytochrome P450 3A5enzyme
DB00342TerfenadineCytochrome P450 3A7enzyme
DB00342TerfenadineMultidrug resistance protein 1transporter
DB00342TerfenadineCytochrome P450 2C8enzyme
DB00342TerfenadineCytochrome P450 2J2enzyme
DB00342TerfenadineMuscarinic acetylcholine receptor M1target
DB00342TerfenadineMuscarinic acetylcholine receptor M5target
DB00342TerfenadineMuscarinic acetylcholine receptor M4target
DB00342TerfenadineMuscarinic acetylcholine receptor M2target
DB00350MinoxidilATP-sensitive inward rectifier potassium channel 1target
DB00350MinoxidilProstaglandin G/H synthase 1target
DB00350MinoxidilRenintarget
DB00357AminoglutethimideCytochrome P450 19A1target
DB00357AminoglutethimideCytochrome P450 1A2enzyme
DB00357AminoglutethimideCytochrome P450 2C19enzyme
DB00357AminoglutethimideCytochrome P450 3A4enzyme
DB00357AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M1target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M2target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M3target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M4target
DB00376TrihexyphenidylMuscarinic acetylcholine receptor M5target
DB00419MiglustatCeramide glucosyltransferasetarget
DB00422MethylphenidateSodium-dependent dopamine transportertarget
DB00422MethylphenidateSodium-dependent noradrenaline transportertarget
DB00422MethylphenidateSodium-dependent serotonin transportertarget
DB00422MethylphenidateCytochrome P450 2D6enzyme
DB00422MethylphenidateCarboxylesteraseenzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Atarget
DB00434CyproheptadineHistamine H1 receptortarget
DB00434CyproheptadineMuscarinic acetylcholine receptor M1target
DB00434CyproheptadineMuscarinic acetylcholine receptor M2target
DB00434CyproheptadineMuscarinic acetylcholine receptor M3target
DB00434Cyproheptadine5-hydroxytryptamine receptor 2Ctarget
DB00434CyproheptadineUDP-glucuronosyltransferase 1-3enzyme
DB00434Cyproheptadine5-hydroxytryptamine receptor 7target
DB00454PethidineKappa-type opioid receptortarget
DB00454PethidineCytochrome P450 2D6enzyme
DB00454PethidineCytochrome P450 2B6enzyme
DB00454PethidineGlutamate receptor ionotropic, NMDA 1target
DB00454PethidineGlutamate receptor ionotropic, NMDA 2Btarget
DB00454PethidineGlutamate receptor ionotropic, NMDA 2Atarget
DB00454PethidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB00454PethidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB00454PethidineCytochrome P450 2C19enzyme
DB00454PethidineCytochrome P450 3A4enzyme
DB00454PethidineSerum albumincarrier
DB00454PethidineAlpha-1-acid glycoprotein 1carrier
DB00454PethidineMuscarinic acetylcholine receptortarget
DB00454PethidineMu-type opioid receptortarget
DB00454PethidineSodium-dependent dopamine transportertarget
DB00454PethidineSodium-dependent noradrenaline transportertarget
DB00454PethidineSodium-dependent serotonin transportertarget
DB00454PethidineLiver carboxylesterase 1target
DB00455LoratadineHistamine H1 receptortarget
DB00455LoratadineCytochrome P450 3A4enzyme
DB00455LoratadineCytochrome P450 2C19enzyme
DB00455LoratadineCytochrome P450 2D6enzyme
DB00455LoratadineCytochrome P450 2C8enzyme
DB00455LoratadineMultidrug resistance protein 1transporter
DB00455LoratadineCytochrome P450 2C9enzyme
DB00455LoratadinePotassium voltage-gated channel subfamily H member 2target
DB00480LenalidomideProstaglandin G/H synthase 2target
DB00480LenalidomideTumor necrosis factor ligand superfamily member 11target
DB00480LenalidomideCadherin-5target
DB00480LenalidomideProtein cereblontarget
DB00480LenalidomideMultidrug resistance protein 1transporter
DB00491MiglitolMaltase-glucoamylase, intestinaltarget
DB00491MiglitolPancreatic alpha-amylaseenzyme
DB00491MiglitolLysosomal alpha-glucosidasetarget
DB00491MiglitolNeutral alpha-glucosidase ABtarget
DB00491MiglitolNeutral alpha-glucosidase Ctarget
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 1A2enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00708SufentanilMu-type opioid receptortarget
DB00708SufentanilDelta-type opioid receptortarget
DB00708SufentanilKappa-type opioid receptortarget
DB00708SufentanilCytochrome P450 3A4enzyme
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineMuscarinic acetylcholine receptor M1target
DB00715ParoxetineMuscarinic acetylcholine receptor M2target
DB00715ParoxetineMuscarinic acetylcholine receptor M3target
DB00715ParoxetineMuscarinic acetylcholine receptor M4target
DB00715ParoxetineMuscarinic acetylcholine receptor M5target
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineMultidrug resistance protein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 2C8enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00719AzatadineHistamine H1 receptortarget
DB00719AzatadineCytochrome P450 3A4enzyme
DB00802AlfentanilMu-type opioid receptortarget
DB00802AlfentanilCytochrome P450 3A4enzyme
DB00802AlfentanilCytochrome P450 3A5enzyme
DB00802AlfentanilAlpha-1-acid glycoprotein 1carrier
DB00802AlfentanilSerum albumincarrier
DB00802AlfentanilCytochrome P450 3A7enzyme
DB00802AlfentanilMultidrug resistance protein 1transporter
DB00810BiperidenNeuronal acetylcholine receptor subunit alpha-2target
DB00810BiperidenMuscarinic acetylcholine receptor M1target
DB00810BiperidenMultidrug resistance protein 1transporter
DB00810BiperidenCytochrome P450 2D6enzyme
DB00813FentanylMu-type opioid receptortarget
DB00813FentanylDelta-type opioid receptortarget
DB00813FentanylCytochrome P450 3A4enzyme
DB00813FentanylCytochrome P450 3A5enzyme
DB00813FentanylCytochrome P450 3A7enzyme
DB00813FentanylMultidrug resistance protein 1transporter
DB00813FentanylKappa-type opioid receptortarget
DB00836LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00836LoperamideMu-type opioid receptortarget
DB00836LoperamideCalmodulintarget
DB00836LoperamidePro-opiomelanocortintarget
DB00836LoperamideDelta-type opioid receptortarget
DB00836LoperamideCytochrome P450 3A4enzyme
DB00836LoperamideMultidrug resistance protein 1transporter
DB00836LoperamideKappa-type opioid receptortarget
DB00836LoperamideCytochrome P450 2C8enzyme
DB00836LoperamideCytochrome P450 2B6enzyme
DB00836LoperamideCytochrome P450 2D6enzyme
DB00836LoperamideNuclear receptor subfamily 1 group I member 3target
DB00906TiagabineSodium- and chloride-dependent GABA transporter 1target
DB00906TiagabineCytochrome P450 3A4enzyme
DB00913AnileridineMu-type opioid receptortarget
DB00920KetotifenHistamine H1 receptortarget
DB00920Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB00950FexofenadineHistamine H1 receptortarget
DB00950FexofenadineMultidrug resistance protein 1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 2B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1A2transporter
DB00950FexofenadineCytochrome P450 2D6enzyme
DB00950FexofenadineSolute carrier organic anion transporter family member 1B1transporter
DB00950FexofenadineSolute carrier organic anion transporter family member 1B3transporter
DB00961MepivacaineSodium channel protein type 10 subunit alphatarget
DB00967DesloratadineHistamine H1 receptortarget
DB00967DesloratadineCytochrome P450 2C9enzyme
DB00967DesloratadineCytochrome P450 2C19enzyme
DB00967DesloratadineCytochrome P450 1A2enzyme
DB00967DesloratadineCytochrome P450 2D6enzyme
DB00967DesloratadineMultidrug resistance protein 1transporter
DB01002LevobupivacaineSodium channel protein type 10 subunit alphatarget
DB01002LevobupivacaineCytochrome P450 3A4enzyme
DB01002LevobupivacaineCytochrome P450 1A2enzyme
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A2enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideDNAtarget
DB01041ThalidomideProtein cereblontarget
DB01041ThalidomideNuclear factor kappa-light-chain-enhancer of activated B cellstarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
DB01074PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
DB01074PerhexilineCytochrome P450 2D6enzyme
DB01074PerhexilineCytochrome P450 2B6enzyme
DB01074PerhexilineCytochrome P450 3A4enzyme
DB01074PerhexilinePotassium voltage-gated channel subfamily H member 2target
DB01081DiphenoxylateMu-type opioid receptortarget
DB01081DiphenoxylateDelta-type opioid receptortarget
DB01107MethyprylonGamma-aminobutyric acid receptor subunit alpha-1target
DB01107MethyprylonCytochrome P450 2D6enzyme
DB01107MethyprylonGABA-A receptor (anion channel)target
DB01184DomperidoneD(2) dopamine receptortarget
DB01184DomperidoneCytochrome P450 3A4enzyme
DB01184DomperidoneCytochrome P450 3A5enzyme
DB01184DomperidoneCytochrome P450 3A7enzyme
DB01184DomperidoneMultidrug resistance protein 1transporter
DB01184DomperidoneCytochrome P450 1A2enzyme
DB01184DomperidoneCytochrome P450 2B6enzyme
DB01184DomperidoneCytochrome P450 2C8enzyme
DB01184DomperidoneCytochrome P450 2D6enzyme
DB01184DomperidoneD(3) dopamine receptortarget
DB01195FlecainideSodium channel protein type 5 subunit alphatarget
DB01195FlecainideCytochrome P450 2D6enzyme
DB01195FlecainideSodium channel protein type 4 subunit alphatarget
DB01195FlecainideCytochrome P450 2C9enzyme
DB01195FlecainidePotassium voltage-gated channel subfamily H member 2target
DB01437GlutethimideCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01437GlutethimideCytochrome P450 2D6enzyme
DB01437GlutethimideGamma-aminobutyric acid receptor subunit alpha-1target
DB01437GlutethimideGABA-A receptor (anion channel)target
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 3Btarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Atarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Ctarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Btarget
DB01520TenocyclidineGlutamate receptor ionotropic, NMDA 2Dtarget
DB01520TenocyclidineAlpha-7 nicotinic cholinergic receptor subunittarget
DB01535CarfentanilMu-type opioid receptortarget
DB01535CarfentanilKappa-type opioid receptortarget
DB01535CarfentanilDelta-type opioid receptortarget
DB01549RolicyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB01549RolicyclidineD(2) dopamine receptortarget
DB015713-MethylfentanylMu-type opioid receptortarget
DB015713-MethylfentanylDelta-type opioid receptortarget
DB015713-MethylfentanylKappa-type opioid receptortarget
DB03206DuvoglustatCyclomaltodextrin glucanotransferasetarget
DB03206DuvoglustatBeta-glucosidase Atarget
DB03206DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DB03206DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DB03206DuvoglustatXylose isomerasetarget
DB03575PhencyclidineGlutamate receptor ionotropic, NMDA 3Atarget
DB03575PhencyclidineSigma non-opioid intracellular receptor 1target
DB03575PhencyclidineCytochrome P450 2B6enzyme
DB039551-deoxymannojirimycinAlpha-mannosidase 2target
DB04842FluspirileneD(2) dopamine receptortarget
DB04842Fluspirilene5-hydroxytryptamine receptor 2Atarget
DB04842FluspirileneVoltage-dependent calcium channel gamma-1 subunittarget
DB05018MigalastatAlpha-galactosidase Atarget
DB05022AmonafideDNA topoisomerase 2-alphatarget
DB05022AmonafideDNA topoisomerase 2-betatarget
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-9target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-10target
DB05137LobelineNeuronal acetylcholine receptor subunit alpha-7target
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB05676ApremilastTumor necrosis factortarget
DB05676ApremilastInterleukin-2target
DB05676ApremilastInterferon gammatarget
DB05676ApremilastNitric oxide synthase, endothelialtarget
DB05676ApremilastCytochrome P450 3A4enzyme
DB06701DexmethylphenidateSodium-dependent dopamine transportertarget
DB06701DexmethylphenidateSodium-dependent noradrenaline transportertarget
DB06701DexmethylphenidateSodium-dependent serotonin transportertarget
DB06701DexmethylphenidateCytochrome P450 2D6enzyme
DB06738KetobemidoneProstaglandin G/H synthase 1enzyme
DB06738KetobemidoneCytochrome P450 2C9enzyme
DB06738KetobemidoneCytochrome P450 3A4enzyme
DB06738KetobemidoneUDP-glucuronosyltransferase 1-9enzyme
DB06738KetobemidoneCytochrome P450 2B6enzyme
DB06738KetobemidoneCytochrome P450 2C19enzyme
DB06738KetobemidoneCytochrome P450 2C8enzyme
DB06738KetobemidoneMu-type opioid receptortarget
DB06738KetobemidoneKappa-type opioid receptortarget
DB06738KetobemidoneDelta-type opioid receptortarget
DB06738KetobemidoneNMDA receptortarget
DB08910PomalidomideCytochrome P450 1A2enzyme
DB08910PomalidomideCytochrome P450 3A4enzyme
DB08910PomalidomideMultidrug resistance protein 1transporter
DB08910PomalidomideProtein cereblontarget
DB08910PomalidomideTumor necrosis factortarget
DB08910PomalidomideProstaglandin G/H synthase 2target
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB11614RupatadineCytochrome P450 3A4enzyme
DB11614RupatadineCytochrome P450 2C9enzyme
DB11614RupatadineCytochrome P450 2C19enzyme
DB11614RupatadineCytochrome P450 2D6enzyme
DB11614RupatadinePlatelet-activating factor receptortarget
DB11614RupatadineHistamine H1 receptortarget
DB12465Ketanserin5-hydroxytryptamine receptor 2Atarget
DB12693Ritanserin5-hydroxytryptamine receptor 2Atarget