General Surgery

Also known as: Surgery / Surgery, General / Operation / Operation NOS / Surgical procedure / Surgical Procedures, Operative

DrugDrug NameDrug Description
DB00673AprepitantAprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV).
DB00612BisoprololBisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only l-bisoprolol exhibits significant β-blocking activity.
DB10771Bovine type I collagenBovine collagen alpha-1 is a naturally occurring extracellular matrix protein which is found in tendons and other connective tissues. It plays a vital role in cell growth, differentiation, attachment, and migration [L2481]. Often combined with other ingredients, such as fibroblasts and keratinocytes, it allows for accelerated and effective wound healing [L2427], [L2450]. Excellagen, a topical gel of bovine type I collagen, is used in the management of wounds including: partial and full- thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/graft, post-Moh’s surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns and skin tears) and draining wounds [L2500]. Bovine type I collagen is also used as a health supplement for bones and joints [A32698]. Interestingly, bovine type I collagen has been studied as a possible endovascular stent material, and has demonstrated promising results in rabbits [A32696].
DB01112CefuroximeBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
DB00475ChlordiazepoxideAn anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
DB00477ChlorpromazineThe prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
DB06779DalteparinDalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000. LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than unfractionated heparin. Dalteparin can also be safely used in most pregnant women. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
DB00303ErtapenemErtapenem is a carbapenem antibiotic marketed by Merck as Invanz. It is structurally very similar to meropenem in that it possess a 1-beta-methyl group.
DB09222Fibrinogen HumanFibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. it is indicated for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
DB10770Foreskin fibroblast (neonatal)Foreskin fibroblast-like stromal cells (FDSCs) are progenitors isolated from human tissue that can differentiate into various cell types [A32660]. Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute. Composed of fibroblasts, extracellular matrix, and a bioabsorbable scaffold, it effectively supports wound healing [L2418]. Dermagraft has only been available in the United States as an investigational device (IDE). Dermagraft for the treatment of diabetic foot ulcers was approved for sale in Canada in 1997. Dermagraft was introduced in the United Kingdom in October 1997, and several other European countries, as well as New Zealand and Australia. The device is available for commercial distribution in Australia, Canada, Finland, France, Hong Kong, Ireland, The Netherlands, New Zealand, Singapore, and The United Kingdom [L2418]. The impact of diabetic foot ulcers (DFU) on individuals and society is devastating. Failure to observe proper wound care in this condition often results in amputation. If wound closure is achieved, it is likely to delay the need for surgical intervention and provide other benefits such as improvements in productivity, mental outlook, social interactions, and time at work, in addition to decreased mortality [L2438]. Interestingly, it has been shown that human foreskin cells possess immunosuppressive properties, which are mediated by other processes than that reported for bone marrow/stromal stem cells [A32655]. Dermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427].
DB10772Foreskin keratinocyte (neonatal)Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a stratified epithelium, with growing basal cells at the innermost layer and the keratinized, and mostly impermeable outer stratum corneum layer on the surface [L2452]. Foreskin keratinocytes are a form of skin cells that are cultured as a skin cell replacement for wounds, to accelerate wound closure and healing [L2434], [L2460]. The defining moment in skin culture was in 1975 when Rheinwald and Green successfully grew human keratinocytes on lethally irradiated murine fibroblasts. In 1981, O’Conner and his group utilized cultured autologous epithelium to coat burn defects for the first time. To construct a "living" alternative, a dermal substitute based on collagen I gel was created with mesenchymal cells such as fibroblasts. When an epidermal layer was added, this approach became known as "skin equivalent", "composite culture" or "organotypical culture" [L2453]. Foreskin keratinocytes are an important ingredient in several skin substitutes [L2460], used for various indications. Keratinocytes are derived from neonatal foreskins and used to create a drug called _Apligraf_, a mixture of [DB10770] and keratinocytes. A gel made of bovine collagen is used as the matrix for cell growth and differentiation. Apligraf has been useful in the treatment of venous leg ulcers and diabetic foot ulcers, by increasing rates of wound healing and decreasing the time required for closure of wounds [L2452]. Orcel, another skin substitute, is similar to Apligraf since it contains both fibroblasts and keratinocytes derived from neonatal foreskin, but in addition, utilizes a type I collagen sponge as its matrix. It is used for grafting onto partial-thickness wounds, where it offers a favorable matrix for host cell migration [L2452].
DB00986GlycopyrroniumGlycopyrronium (as the bromide salt glycopyrrolate) is a synthetic anticholinergic agent with a quaternary ammonium structure. A muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. In October 2015, glycopyrrolate was approved by the FDA for use as a standalone treatment for Chronic obstructive pulmonary disease (COPD), as Seebri Neohaler.
DB00889GranisetronA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients. [PubChem]
DB01109HeparinUnfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate.
DB01137LevofloxacinA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
DB08813NadroparinNadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. The amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons. Low molecular weight heparins are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
DB00085PancrelipasePancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.[L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and [DB13147].
DB06822TinzaparinTinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin III (ATIII). This complex greatly accelerates the inhibition of factor Xa. It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally. LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
DB00662TrimethobenzamideTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
DrugDrug NameTargetType
DB00673AprepitantSubstance-P receptortarget
DB00673AprepitantCytochrome P450 3A4enzyme
DB00673AprepitantCytochrome P450 2C9enzyme
DB00673AprepitantCytochrome P450 3A5enzyme
DB00673AprepitantCytochrome P450 3A7enzyme
DB00673AprepitantCytochrome P450 2C19enzyme
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 2D6enzyme
DB00612BisoprololCytochrome P450 3A4enzyme
DB01112CefuroximePenicillin-binding protein 1Atarget
DB01112CefuroximeSolute carrier family 15 member 1transporter
DB01112CefuroximeSolute carrier family 15 member 2transporter
DB00475ChlordiazepoxideCytochrome P450 3A4enzyme
DB00475ChlordiazepoxideGABA-A receptor (anion channel)target
DB00477ChlorpromazineD(2) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Atarget
DB00477ChlorpromazineCytochrome P450 2D6enzyme
DB00477ChlorpromazineCholinesteraseenzyme
DB00477ChlorpromazineCytochrome P450 1A2enzyme
DB00477ChlorpromazineSerum albumincarrier
DB00477ChlorpromazineMultidrug resistance protein 1transporter
DB00477ChlorpromazineD(1A) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 1Atarget
DB00477ChlorpromazineAlpha-1A adrenergic receptortarget
DB00477ChlorpromazineAlpha-1B adrenergic receptortarget
DB00477ChlorpromazineCytochrome P450 2E1enzyme
DB00477ChlorpromazineCytochrome P450 3A4enzyme
DB00477ChlorpromazineHistamine H1 receptortarget
DB00477ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
DB00477ChlorpromazineD(1) dopamine receptortarget
DB00477ChlorpromazineD(3) dopamine receptortarget
DB00477ChlorpromazineD(4) dopamine receptortarget
DB00477ChlorpromazineD(1B) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
DB00477Chlorpromazine5-hydroxytryptamine 2 receptortarget
DB00477ChlorpromazineAlpha-1 adrenergic receptorstarget
DB00477ChlorpromazineAlpha-2 adrenergic receptorstarget
DB00477ChlorpromazineMuscarinic acetylcholine receptor M1target
DB00477ChlorpromazineMuscarinic acetylcholine receptor M3target
DB00477ChlorpromazineSphingomyelin phosphodiesterasetarget
DB00477ChlorpromazineCalmodulintarget
DB00477Chlorpromazinealpha1-acid glycoproteintarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 6target
DB00477Chlorpromazine5-hydroxytryptamine receptor 7target
DB00477ChlorpromazineHistamine H4 receptortarget
DB00477ChlorpromazineBile salt export pumptransporter
DB06779DalteparinVascular endothelial growth factor Atarget
DB06779DalteparinTissue factor pathway inhibitortarget
DB06779DalteparinHeparanaseenzyme
DB06779DalteparinAntithrombin-IIItarget
DB06779DalteparinP-selectintarget
DB00303ErtapenemPenicillin-binding protein 2target
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 1Atarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00303ErtapenemPenicillin-binding protein 1Btarget
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 2target
DB10770Foreskin fibroblast (neonatal)Interleukin-6target
DB10770Foreskin fibroblast (neonatal)Vascular endothelial growth factor receptor 1target
DB10770Foreskin fibroblast (neonatal)Interleukin-1 receptor type 1target
DB10770Foreskin fibroblast (neonatal)TGF-beta receptor type-2target
DB10770Foreskin fibroblast (neonatal)Fibroblast growth factor 1target
DB10770Foreskin fibroblast (neonatal)Interferon gammatarget
DB10770Foreskin fibroblast (neonatal)Fibroblast growth factor receptor 2target
DB10770Foreskin fibroblast (neonatal)Granulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
DB10770Foreskin fibroblast (neonatal)Platelet-derived growth factor receptor betatarget
DB10770Foreskin fibroblast (neonatal)Transforming growth factor beta-1target
DB10770Foreskin fibroblast (neonatal)Tumor necrosis factortarget
DB10772Foreskin keratinocyte (neonatal)Fibroblast growth factor 1target
DB10772Foreskin keratinocyte (neonatal)Epidermal growth factor receptortarget
DB10772Foreskin keratinocyte (neonatal)Granulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
DB10772Foreskin keratinocyte (neonatal)Interleukin-1 betatarget
DB10772Foreskin keratinocyte (neonatal)Interleukin-6target
DB10772Foreskin keratinocyte (neonatal)Interferon gammatarget
DB10772Foreskin keratinocyte (neonatal)Fibroblast growth factor receptor 2target
DB10772Foreskin keratinocyte (neonatal)Platelet-derived growth factor receptor alphatarget
DB10772Foreskin keratinocyte (neonatal)TGF-beta receptor type-2target
DB10772Foreskin keratinocyte (neonatal)Transforming growth factor beta-1target
DB10772Foreskin keratinocyte (neonatal)Tumor necrosis factortarget
DB10772Foreskin keratinocyte (neonatal)Vascular endothelial growth factor Atarget
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M1target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M3target
DB00986GlycopyrroniumMuscarinic acetylcholine receptor M2target
DB00889Granisetron5-hydroxytryptamine receptor 3Atarget
DB00889GranisetronCytochrome P450 3A4enzyme
DB00889GranisetronCytochrome P450 1A1enzyme
DB01109HeparinAntithrombin-IIItarget
DB01109HeparinCoagulation factor Xtarget
DB01109HeparinP-selectintarget
DB01109HeparinHeparanaseenzyme
DB01109HeparinFibroblast growth factor receptor 4target
DB01109HeparinFibroblast growth factor 4target
DB01109HeparinFibroblast growth factor 19target
DB01109HeparinFibroblast growth factor receptor 1target
DB01109HeparinFibroblast growth factor 1target
DB01109HeparinFibroblast growth factor receptor 2target
DB01109HeparinFibroblast growth factor 2target
DB01109HeparinPlatelet factor 4target
DB01109HeparinHepatocyte growth factortarget
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinMultidrug resistance protein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB08813NadroparinProto-oncogene c-Fostarget
DB08813NadroparinMyc proto-oncogene proteintarget
DB08813NadroparinP-selectintarget
DB08813NadroparinAntithrombin-IIItarget
DB00085PancrelipaseDietary fattarget
DB00085PancrelipaseDietary proteintarget
DB00085PancrelipaseDietary starchtarget
DB06822TinzaparinAntithrombin-IIItarget
DB06822TinzaparinA disintegrin and metalloproteinase with thrombospondin motifs 4enzyme
DB06822TinzaparinIntegrin alpha-4target
DB06822TinzaparinStromal cell-derived factor 1target
DrugDrug NamePhaseStatusCount
DB01240Epoprostenol1Completed1
DB00297Bupivacaine1 / 2Recruiting1
DB01327Cefazolin1 / 2Completed1
DB01234Dexamethasone1 / 2Recruiting1
DB09374Indocyanine green acid form1 / 2Enrolling by Invitation1
DB09287Polyethylene glycol1 / 2Completed1
DB11077Polyethylene glycol 4001 / 2Completed1
DB09153Sodium Chloride1 / 2Recruiting1
DB00316Acetaminophen2Recruiting1
DB00297Bupivacaine2Not Yet Recruiting1
DB01164Calcium Chloride2Completed1
DB11330Factor IX Complex (Human)2Not Yet Recruiting1
DB01050Ibuprofen2Recruiting1
DB01221Ketamine2Completed1
DB04398Lactic Acid2Completed1
DB05313MP42Completed1
DB12583Maltodextrin2Withdrawn1
DB04817Metamizole2Recruiting1
DB00295Morphine2Not Yet Recruiting1
DB00497Oxycodone2Recruiting1
DB00761Potassium Chloride2Completed1
DB09153Sodium Chloride2Completed1
DB00513Aminocaproic Acid2 / 3Completed1
DB06196Icatibant2 / 3Completed1
DB00465Ketorolac2 / 3Completed1
DB00526Oxaliplatin2 / 3Recruiting1
DB01101Capecitabine3Active Not Recruiting1
DB01101Capecitabine3Completed1
DB00878Chlorhexidine3Completed2
DB00515Cisplatin3Completed1
DB09222Fibrinogen Human3Recruiting1
DB00544Fluorouracil3Recruiting1
DB00569Fondaparinux3Completed1
DB11728Fondaparinux3Completed1
DB00986Glycopyrronium3Recruiting1
DB00762Irinotecan3Recruiting1
DB02325Isopropyl Alcohol3Completed1
DB12041Mapracorat3Completed2
DB01400Neostigmine3Recruiting1
DB00526Oxaliplatin3Active Not Recruiting1
DB00296Ropivacaine3Not Yet Recruiting1
DB09153Sodium Chloride3Not Yet Recruiting1
DB09153Sodium Chloride3Recruiting2
DB06206Sugammadex3Recruiting1
DB00302Tranexamic Acid3Completed1
DB00302Tranexamic Acid3Recruiting2
DB00512Vancomycin3Recruiting1
DB00284Acarbose4Completed1
DB00316Acetaminophen4Completed1
DB00335Atenolol4Unknown Status1
DB01076Atorvastatin4Unknown Status1
DB09020Bisacodyl4Completed1
DB00297Bupivacaine4Completed1
DB00921Buprenorphine4Not Yet Recruiting1
DB00286Conjugated estrogens4Withdrawn1
DB01234Dexamethasone4Recruiting1
DB01234Dexamethasone4Terminated1
DB00633Dexmedetomidine4Completed2
DB00633Dexmedetomidine4Recruiting1
DB11089Docusate4Completed1
DB01225Enoxaparin4Recruiting1
DB01225Enoxaparin4Unknown Status1
DB00668Epinephrine4Completed2
DB00783Estradiol4Withdrawn1
DB09106Hydroxyethyl Starch4Completed1
DB01050Ibuprofen4Completed1
DB00047Insulin Glargine4Completed1
DB01592Iron4Recruiting1
DB01221Ketamine4Recruiting1
DB01221Ketamine4Withdrawn1
DB01009Ketoprofen4Completed1
DB04465Lactose4Completed1
DB01002Levobupivacaine4Completed1
DB00281Lidocaine4Completed1
DB06655Liraglutide4Completed1
DB14158Microcrystalline cellulose4Recruiting1
DB00683Midazolam4Recruiting1
DB00295Morphine4Completed1
DB01183Naloxone4Not Yet Recruiting1
DB00184Nicotine4Recruiting1
DB00646Nystatin4Completed1
DB06663Pasireotide4Completed1
DB03088Pidolic Acid4Completed1
DB00818Propofol4Completed3
DB00818Propofol4Recruiting3
DB00899Remifentanil4Recruiting1
DB00728Rocuronium4Completed1
DB00728Rocuronium4Not Yet Recruiting3
DB00296Ropivacaine4Completed1
DB00296Ropivacaine4Recruiting1
DB00296Ropivacaine4Terminated1
DB01236Sevoflurane4Completed2
DB01236Sevoflurane4Recruiting1
DB01261Sitagliptin4Completed1
DB09153Sodium Chloride4Completed2
DB09153Sodium Chloride4Not Yet Recruiting2
DB09153Sodium Chloride4Recruiting2
DB09153Sodium Chloride4Withdrawn1
DB01638Sorbitol4Completed1
DB09422Soybean oil4Recruiting1
DB06206Sugammadex4Enrolling by Invitation1
DB06206Sugammadex4Not Yet Recruiting1
DB00302Tranexamic Acid4Recruiting1
DB00897Triazolam4Recruiting1
DB00661Verapamil4Completed1
DB00316AcetaminophenNot AvailableActive Not Recruiting1
DB00316AcetaminophenNot AvailableEnrolling by Invitation1
DB00316AcetaminophenNot AvailableRecruiting1
DB00479AmikacinNot AvailableRecruiting1
DB13913BelladonnaNot AvailableCompleted1
DB00297BupivacaineNot AvailableCompleted2
DB01190ClindamycinNot AvailableRecruiting1
DB01189DesfluraneNot AvailableCompleted2
DB01234DexamethasoneNot AvailableCompleted1
DB01234DexamethasoneNot AvailableEnrolling by Invitation1
DB00633DexmedetomidineNot AvailableUnknown Status1
DB00514DextromethorphanNot AvailableCompleted1
DB00586DiclofenacNot AvailableActive Not Recruiting1
DB00586DiclofenacNot AvailableRecruiting1
DB01075DiphenhydramineNot AvailableCompleted1
DB00450DroperidolNot AvailableNot Yet Recruiting1
DB01225EnoxaparinNot AvailableUnknown Status1
DB00016ErythropoietinNot AvailableRecruiting1
DB00813FentanylNot AvailableCompleted2
DB00813FentanylNot AvailableRecruiting1
DB13961Fish oilNot AvailableEnrolling by Invitation1
DB00301FlucloxacillinNot AvailableRecruiting1
DB00327HydromorphoneNot AvailableCompleted1
DB01050IbuprofenNot AvailableActive Not Recruiting1
DB01221KetamineNot AvailableRecruiting1
DB00281LidocaineNot AvailableCompleted1
DB00281LidocaineNot AvailableTerminated1
DB00281LidocaineNot AvailableWithdrawn1
DB00760MeropenemNot AvailableRecruiting1
DB00683MidazolamNot AvailableCompleted2
DB00683MidazolamNot AvailableRecruiting1
DB00295MorphineNot AvailableActive Not Recruiting1
DB00844NalbuphineNot AvailableRecruiting3
DB00788NaproxenNot AvailableActive Not Recruiting1
DB00788NaproxenNot AvailableRecruiting1
DB00994NeomycinNot AvailableActive Not Recruiting1
DB00622NicardipineNot AvailableRecruiting1
DB00104OctreotideNot AvailableEnrolling by Invitation1
DB00104OctreotideNot AvailableUnknown Status1
DB00526OxaliplatinNot AvailableCompleted1
DB00497OxycodoneNot AvailableActive Not Recruiting1
DB00497OxycodoneNot AvailableRecruiting1
DB00388PhenylephrineNot AvailableRecruiting1
DB00818PropofolNot AvailableCompleted3
DB00818PropofolNot AvailableNot Yet Recruiting1
DB00818PropofolNot AvailableRecruiting3
DB00899RemifentanilNot AvailableCompleted3
DB00899RemifentanilNot AvailableTerminated1
DB00728RocuroniumNot AvailableNot Yet Recruiting1
DB00728RocuroniumNot AvailableRecruiting1
DB00296RopivacaineNot AvailableCompleted1
DB00296RopivacaineNot AvailableWithdrawn1
DB01236SevofluraneNot AvailableCompleted2
DB01236SevofluraneNot AvailableRecruiting1
DB09153Sodium ChlorideNot AvailableEnrolling by Invitation1
DB09153Sodium ChlorideNot AvailableRecruiting1
DB00202SuccinylcholineNot AvailableRecruiting1
DB00708SufentanilNot AvailableNot Yet Recruiting1
DB00795SulfasalazineNot AvailableEnrolling by Invitation1
DB00193TramadolNot AvailableActive Not Recruiting1
DB00193TramadolNot AvailableRecruiting1
DB00302Tranexamic AcidNot AvailableEnrolling by Invitation1
DB12661UrapidilNot AvailableRecruiting2